Published in Mol Cell Biochem on February 11, 2010
Sirtuins as regulators of metabolism and healthspan. Nat Rev Mol Cell Biol (2012) 4.86
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab (2012) 1.93
Targeting sirtuin 1 to improve metabolism: all you need is NAD(+)? Pharmacol Rev (2011) 1.85
The dynamic regulation of NAD metabolism in mitochondria. Trends Endocrinol Metab (2012) 1.55
Resveratrol increases AdipoR1 and AdipoR2 expression in type 2 diabetic nephropathy. J Transl Med (2016) 1.38
SIRT1 and energy metabolism. Acta Biochim Biophys Sin (Shanghai) (2013) 1.25
The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity. Handb Exp Pharmacol (2011) 1.16
Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning. PLoS One (2011) 1.10
The ways and means that fine tune Sirt1 activity. Trends Biochem Sci (2013) 1.07
Fluoride induces oxidative damage and SIRT1/autophagy through ROS-mediated JNK signaling. Free Radic Biol Med (2015) 0.93
Mitochondrial sirtuins and metabolic homeostasis. Best Pract Res Clin Endocrinol Metab (2012) 0.92
A time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiology. J Mol Cell Cardiol (2014) 0.89
Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer. Genes Cancer (2013) 0.83
Mitochondrial matrix Ca²⁺ accumulation regulates cytosolic NAD⁺/NADH metabolism, protein acetylation, and sirtuin expression. Mol Cell Biol (2014) 0.83
Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human. Antioxid Redox Signal (2013) 0.81
Impact of metabolic regulators on the expression of the obesity associated genes FTO and NAMPT in human preadipocytes and adipocytes. PLoS One (2011) 0.80
Interferon regulatory factor 9 is critical for neointima formation following vascular injury. Nat Commun (2014) 0.79
Hepatic sirtuin 1 is dispensable for fibrate-induced peroxisome proliferator-activated receptor-α function in vivo. Am J Physiol Endocrinol Metab (2014) 0.78
An acetylation rheostat for the control of muscle energy homeostasis. J Mol Endocrinol (2013) 0.78
The reversal effects of 3-bromopyruvate on multidrug resistance in vitro and in vivo derived from human breast MCF-7/ADR cells. PLoS One (2014) 0.78
Sirtuin 1: A Target for Kidney Diseases. Mol Med (2015) 0.77
Enhancement of NAD+-dependent SIRT1 deacetylase activity by methylselenocysteine resets the circadian clock in carcinogen-treated mammary epithelial cells. Oncotarget (2015) 0.77
Can short-term fasting protect against doxorubicin-induced cardiotoxicity? World J Biol Chem (2014) 0.76
Vascular Smooth Muscle Sirtuin-1 Protects Against Diet-Induced Aortic Stiffness. Hypertension (2016) 0.75
PPARα Agonist WY-14643 Induces SIRT1 Activity in Rat Fatty Liver Ischemia-Reperfusion Injury. Biomed Res Int (2015) 0.75
Effects of acute doxorubicin treatment on hepatic proteome lysine acetylation status and the apoptotic environment. World J Biol Chem (2014) 0.75
Metabolic control by sirtuins and other enzymes that sense NAD(+), NADH, or their ratio. Biochim Biophys Acta (2017) 0.75
The androgen receptor governs the execution, but not programming, of male sexual and territorial behaviors. Neuron (2010) 2.26
Estrogen masculinizes neural pathways and sex-specific behaviors. Cell (2009) 2.15
Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112). Int Immunol (2004) 1.92
CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. J Exp Med (2003) 1.82
Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model. Proc Natl Acad Sci U S A (2005) 1.67
Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities. Biochem Pharmacol (2003) 1.61
The aromatase knock-out mouse provides new evidence that estradiol is required during development in the female for the expression of sociosexual behaviors in adulthood. J Neurosci (2002) 1.42
Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization. J Physiol (2008) 1.28
A molecular mechanism regulating circadian expression of vascular endothelial growth factor in tumor cells. Cancer Res (2003) 1.26
Protective effects of carotenoids from saffron on neuronal injury in vitro and in vivo. Biochim Biophys Acta (2006) 1.26
Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation. J Exp Med (2003) 1.21
Crocin prevents the death of rat pheochromyctoma (PC-12) cells by its antioxidant effects stronger than those of alpha-tocopherol. Neurosci Lett (2004) 1.04
Chronic treatment with prednisolone represses the circadian oscillation of clock gene expression in mouse peripheral tissues. Mol Endocrinol (2005) 1.01
Anti-apoptotic roles of plasminogen activator inhibitor-1 as a neurotrophic factor in the central nervous system. Thromb Haemost (2008) 0.98
Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment. J Neurosci (2010) 0.98
High expression of the longevity gene product SIRT1 and apoptosis induction by sirtinol in adult T-cell leukemia cells. Int J Cancer (2012) 0.98
Dual assemblies of an activating immune receptor, MAIR-II, with ITAM-bearing adapters DAP12 and FcRgamma chain on peritoneal macrophages. J Immunol (2007) 0.93
Molecular and functional characteristics of the Fcalpha/muR, a novel Fc receptor for IgM and IgA. Springer Semin Immunopathol (2006) 0.91
Inhibition of lipopolysaccharide-induced release of interleukin-8 from intestinal epithelial cells by SMA, a novel inhibitor of sphingomyelinase and its therapeutic effect on dextran sulphate sodium-induced colitis in mice. Cell Immunol (2007) 0.89
Inhibition of sphingomyelinase activity helps to prevent neuron death caused by ischemic stress. Neurochem Int (2004) 0.89
An attempt to promote neo-vascularization by employing a newly synthesized inhibitor of protein tyrosine phosphatase. FEBS Lett (2002) 0.88
Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis. Neurochem Int (2004) 0.86
Lack of estrogen increases pain in the trigeminal formalin model: a behavioural and immunocytochemical study of transgenic ArKO mice. Pain (2005) 0.85
Synthesis of non-competitive inhibitors of sphingomyelinases with significant activity. Bioorg Med Chem Lett (2003) 0.85
HTLV-1 provirus load in peripheral blood lymphocytes of HTLV-1 carriers is diminished by green tea drinking. Cancer Sci (2004) 0.85
Anti-HTLV-1 tax antibody and tax-specific cytotoxic T lymphocyte are associated with a reduction in HTLV-1 proviral load in asymptomatic carriers. J Med Virol (2007) 0.84
Liposomes and nanotechnology in drug development: focus on oncotargets. Int J Nanomedicine (2012) 0.83
Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. Int J Cancer (2003) 0.82
Estrogen receptor-independent catechol estrogen binding activity: protein binding studies in wild-type, Estrogen receptor-alpha KO, and aromatase KO mice tissues. Biochemistry (2004) 0.82
Proxisome proliferator-activated receptor-α mediates high-fat, diet-enhanced daily oscillation of plasminogen activator inhibitor-1 activity in mice. Chronobiol Int (2010) 0.82
Impairment of spatial learning by estradiol treatment in female mice is attenuated by estradiol exposure during development. Horm Behav (2006) 0.81
Molecular mechanism for neuro-protective effect of prosaposin against oxidative stress: its regulation of dimeric transcription factor formation. Biochim Biophys Acta (2008) 0.81
Oligomannose-coated liposomes efficiently induce human T-cell leukemia virus-1-specific cytotoxic T lymphocytes without adjuvant. FEBS J (2011) 0.80
Molecular characteristics of IgA and IgM Fc binding to the Fcalpha/muR. Biochem Biophys Res Commun (2006) 0.80
Vasohibin induces prolyl hydroxylase-mediated degradation of hypoxia-inducible factor-1α in human umbilical vein endothelial cells. FEBS Lett (2012) 0.80
Target epitopes of HTLV-1 recognized by class I MHC-restricted cytotoxic T lymphocytes in patients with myelopathy and spastic paraparesis and infected patients with autoimmune disorders. J Med Virol (2011) 0.80
Efficient induction of human T-cell leukemia virus-1-specific CTL by chimeric particle without adjuvant as a prophylactic for adult T-cell leukemia. Mol Immunol (2009) 0.79
Modulation of circadian rhythm of DNA synthesis in tumor cells by inhibiting platelet-derived growth factor signaling. J Pharmacol Sci (2008) 0.79
[Investigation of the combination of aspirin with non-steroidal anti-inflammatory drugs]. Yakugaku Zasshi (2011) 0.79
Identification of the Fcalpha/muR isoform specifically expressed in the kidney tubules. Mol Immunol (2008) 0.79
Covalent binding of nitroso-sulfonamides to glutathione S-transferase in guinea pigs with delayed type hypersensitivity. Int Immunopharmacol (2012) 0.79
Biochemistry and neurobiology of prosaposin: a potential therapeutic neuro-effector. Cent Nerv Syst Agents Med Chem (2009) 0.78
Assessment of peripheral blood CD4+ adenosine triphosphate activity in patients with rheumatoid arthritis. Mod Rheumatol (2012) 0.78
24-hour oscillation of mouse methionine aminopeptidase2, a regulator of tumor progression, is regulated by clock gene proteins. Cancer Res (2004) 0.77
The stimulatory effects of caffeine with oseltamivir (Tamiflu) on light-dark behavior and open-field behavior in mice. Neurosci Lett (2009) 0.77
Bezafibrate induces plasminogen activator inhibitor-1 gene expression in a CLOCK-dependent circadian manner. Mol Pharmacol (2010) 0.77
Circadian regulation of mouse topoisomerase I gene expression by glucocorticoid hormones. Biochem Pharmacol (2006) 0.77
Novel cytotoxic isolated from Jamaican Hyptis verticillata jacq induces apoptosis and overcomes multidrug resistance. Anticancer Res (2011) 0.76
Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors. Bioorg Med Chem (2005) 0.76
Optimizing the dosing schedule of TNP-470 [O-(chloroacetyl-carbamoyl) fumagillol] enhances its antitumor and antiangiogenic efficacies. J Pharmacol Exp Ther (2003) 0.76
Effects of exogenous interleukin-7 on CD8(+) T-cell survival and function in human T-cell lymphotropic virus type 1 infection. Leuk Lymphoma (2013) 0.76
[The role of pharmacist on coordinating CAPD operation]. Gan To Kagaku Ryoho (2008) 0.75
Diastereoselective synthesis of gamma-amino-delta-hydroxy-alpha,alpha-difluorophosphonates: a vehicle for structure-activity relationship studies on SMA-7, a potent sphingomyelinase inhibitor. J Org Chem (2009) 0.75
Effects of experimental diabetes on hepatic drug metabolism in rats: the activities of flavin-containing monooxygenase, the phase II conjugation reactions and glutathione related enzymes. Res Commun Mol Pathol Pharmacol (2005) 0.75
Prediction of antiplatelet effects of aspirin in vivo based on in vitro results. Clin Appl Thromb Hemost (2013) 0.75
Glucocorticoid regulation of 24-hour oscillation in interferon receptor gene expression in mouse liver. Endocrinology (2006) 0.75