Published in Hypertension on July 18, 2016
Sirtuins, a promising target in slowing down the ageing process. Biogerontology (2017) 0.80
Resveratrol improves health and survival of mice on a high-calorie diet. Nature (2006) 20.91
Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov (2006) 11.77
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science (2004) 11.39
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J (2004) 11.00
Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association. Circulation (2015) 10.14
Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation (2010) 9.09
Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol (2010) 8.55
Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation (2006) 8.18
Prognostic value of aortic pulse wave velocity as index of arterial stiffness in the general population. Circulation (2006) 7.01
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation (2005) 6.89
Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol (2005) 6.34
Aortic stiffness, blood pressure progression, and incident hypertension. JAMA (2012) 6.01
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases. Cell (2012) 5.71
Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol (2005) 5.39
Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci U S A (2008) 5.21
Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study. Nature (2012) 5.00
SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab (2008) 4.89
Prediction of cardiovascular events and all-cause mortality with central haemodynamics: a systematic review and meta-analysis. Eur Heart J (2010) 4.69
Pulse wave velocity is an independent predictor of the longitudinal increase in systolic blood pressure and of incident hypertension in the Baltimore Longitudinal Study of Aging. J Am Coll Cardiol (2008) 2.75
Aortic stiffness is associated with visceral adiposity in older adults enrolled in the study of health, aging, and body composition. Hypertension (2001) 2.46
Modulation of vascular smooth muscle signaling by reactive oxygen species. Physiology (Bethesda) (2006) 2.24
Longitudinal trajectories of arterial stiffness and the role of blood pressure: the Baltimore Longitudinal Study of Aging. Hypertension (2013) 2.15
Calorie restriction and SIR2 genes--towards a mechanism. Mech Ageing Dev (2005) 1.79
Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin. J Biol Chem (2000) 1.67
Arterial stiffening precedes systolic hypertension in diet-induced obesity. Hypertension (2013) 1.65
Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. Hypertension (2016) 1.60
Short communication: vascular smooth muscle cell stiffness as a mechanism for increased aortic stiffness with aging. Circ Res (2010) 1.56
Biochemical effects of SIRT1 activators. Biochim Biophys Acta (2009) 1.16
Reduced vascular nitric oxide-cGMP signaling contributes to adipose tissue inflammation during high-fat feeding. Arterioscler Thromb Vasc Biol (2011) 1.11
Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell (2013) 1.11
Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice. Mol Cell Biochem (2010) 1.10
Sirtuin-1 regulation of mammalian metabolism. Trends Mol Med (2011) 1.07
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metab (2014) 1.02
Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells. Free Radic Biol Med (2013) 0.96
Central Arterial Aging and Angiotensin II Signaling. Curr Hypertens Rev (2010) 0.95
Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice. Free Radic Res (2003) 0.93
"Smooth Muscle Cell Stiffness Syndrome"-Revisiting the Structural Basis of Arterial Stiffness. Front Physiol (2015) 0.88
Relation of Central Arterial Stiffness to Incident Heart Failure in the Community. J Am Heart Assoc (2015) 0.87
Aging impairs smooth muscle-mediated regulation of aortic stiffness: a defect in shock absorption function? Am J Physiol Heart Circ Physiol (2014) 0.86
Resveratrol attenuates high glucose-induced oxidative stress and cardiomyocyte apoptosis through AMPK. Mol Cell Endocrinol (2015) 0.85
Association of arterial stiffness with progression of subclinical brain and cognitive disease. Neurology (2016) 0.84
Vascular Smooth Muscle Sirtuin-1 Protects Against Aortic Dissection During Angiotensin II-Induced Hypertension. J Am Heart Assoc (2015) 0.83
Nox2 mediates high fat high sucrose diet-induced nitric oxide dysfunction and inflammation in aortic smooth muscle cells. J Mol Cell Cardiol (2014) 0.82
Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human. Antioxid Redox Signal (2013) 0.81
Aortic stiffness and kidney disease in an elderly population. Am J Nephrol (2015) 0.79
Carotid arterial stiffness and risk of incident cerebral microbleeds in older people: the Age, Gene/Environment Susceptibility (AGES)-Reykjavik study. Arterioscler Thromb Vasc Biol (2015) 0.78
Sirtuins 1 and 2 Are Universal Histone Deacetylases. ACS Chem Biol (2016) 0.76