X Edward Guo

Author PubWeight™ 112.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure. Cell 2009 3.28
2 Engineering anatomically shaped human bone grafts. Proc Natl Acad Sci U S A 2009 2.37
3 Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nat Med 2010 2.32
4 Quantification of the roles of trabecular microarchitecture and trabecular type in determining the elastic modulus of human trabecular bone. J Bone Miner Res 2006 2.21
5 miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol 2012 2.15
6 Mechano-electrochemical properties of articular cartilage: their inhomogeneities and anisotropies. Annu Rev Biomed Eng 2002 2.04
7 High-resolution peripheral quantitative computed tomography can assess microstructural and mechanical properties of human distal tibial bone. J Bone Miner Res 2010 2.01
8 Complete volumetric decomposition of individual trabecular plates and rods and its morphological correlations with anisotropic elastic moduli in human trabecular bone. J Bone Miner Res 2008 1.89
9 Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study. J Clin Endocrinol Metab 2013 1.88
10 Differences in bone microarchitecture between postmenopausal Chinese-American and white women. J Bone Miner Res 2011 1.86
11 Efficacy of serotonin inhibition in mouse models of bone loss. J Bone Miner Res 2011 1.84
12 Abnormal microarchitecture and reduced stiffness at the radius and tibia in postmenopausal women with fractures. J Bone Miner Res 2010 1.78
13 Anatomically shaped osteochondral constructs for articular cartilage repair. J Biomech 2003 1.64
14 Bone microarchitecture and stiffness in premenopausal women with idiopathic osteoporosis. J Clin Endocrinol Metab 2009 1.61
15 The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin. Bone 2011 1.51
16 Bone density, geometry, microstructure, and stiffness: Relationships between peripheral and central skeletal sites assessed by DXA, HR-pQCT, and cQCT in premenopausal women. J Bone Miner Res 2010 1.50
17 Individual trabeculae segmentation (ITS)-based morphological analysis of high-resolution peripheral quantitative computed tomography images detects abnormal trabecular plate and rod microarchitecture in premenopausal women with idiopathic osteoporosis. J Bone Miner Res 2010 1.46
18 Osteoblast elastic modulus measured by atomic force microscopy is substrate dependent. Ann Biomed Eng 2005 1.43
19 Advanced tools for tissue engineering: scaffolds, bioreactors, and signaling. Tissue Eng 2006 1.41
20 In vivo microMRI-based finite element and morphological analyses of tibial trabecular bone in eugonadal and hypogonadal men before and after testosterone treatment. J Bone Miner Res 2008 1.40
21 Individual trabecula segmentation (ITS)-based morphological analyses and microfinite element analysis of HR-pQCT images discriminate postmenopausal fragility fractures independent of DXA measurements. J Bone Miner Res 2012 1.40
22 Dissociation of the neuronal regulation of bone mass and energy metabolism by leptin in vivo. Proc Natl Acad Sci U S A 2008 1.34
23 Better skeletal microstructure confers greater mechanical advantages in Chinese-American women versus white women. J Bone Miner Res 2011 1.34
24 An application of nanoindentation technique to measure bone tissue Lamellae properties. J Biomech Eng 2005 1.32
25 Optimizing the medium perfusion rate in bone tissue engineering bioreactors. Biotechnol Bioeng 2010 1.28
26 Micromechanical analyses of vertebral trabecular bone based on individual trabeculae segmentation of plates and rods. J Biomech 2008 1.25
27 Indentation determined mechanoelectrochemical properties and fixed charge density of articular cartilage. Ann Biomed Eng 2004 1.25
28 Individual trabecula segmentation (ITS)-based morphological analysis of microscale images of human tibial trabecular bone at limited spatial resolution. J Bone Miner Res 2011 1.24
29 Adiponectin regulates bone mass via opposite central and peripheral mechanisms through FoxO1. Cell Metab 2013 1.19
30 Primary hyperparathyroidism is associated with abnormal cortical and trabecular microstructure and reduced bone stiffness in postmenopausal women. J Bone Miner Res 2013 1.17
31 Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual. J Exp Med 2011 1.16
32 In vivo evaluation of a multiphased scaffold designed for orthopaedic interface tissue engineering and soft tissue-to-bone integration. J Biomed Mater Res A 2008 1.15
33 Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment. J Bone Miner Res 2003 1.12
34 Abnormal microarchitecture and stiffness in postmenopausal women with ankle fractures. J Clin Endocrinol Metab 2011 1.12
35 Calcium response in osteocytic networks under steady and oscillatory fluid flow. Bone 2012 1.11
36 Effects of trabecular type and orientation on microdamage susceptibility in trabecular bone. Bone 2010 1.11
37 CREB mediates brain serotonin regulation of bone mass through its expression in ventromedial hypothalamic neurons. Genes Dev 2010 1.09
38 Osteocytic network is more responsive in calcium signaling than osteoblastic network under fluid flow. J Bone Miner Res 2012 1.08
39 The dependence of transversely isotropic elasticity of human femoral cortical bone on porosity. J Biomech 2004 1.08
40 In vitro model of vascularized bone: synergizing vascular development and osteogenesis. PLoS One 2011 1.06
41 Computational biomechanics of the distal tibia from high-resolution MR and micro-CT images. Bone 2010 1.04
42 An ATP-dependent mechanism mediates intercellular calcium signaling in bone cell network under single cell nanoindentation. Cell Calcium 2010 1.03
43 Transgenic complementation of leptin receptor deficiency. II. Increased leptin receptor transgene dose effects on obesity/diabetes and fertility/lactation in lepr-db/db mice. Am J Physiol Endocrinol Metab 2003 1.03
44 The functional environment of chondrocytes within cartilage subjected to compressive loading: a theoretical and experimental approach. Biorheology 2002 1.03
45 Osteocyte viability and regulation of osteoblast function in a 3D trabecular bone explant under dynamic hydrostatic pressure. J Bone Miner Res 2004 1.01
46 Influence of vertical trabeculae on the compressive strength of the human vertebra. J Bone Miner Res 2011 1.01
47 In situ intracellular calcium oscillations in osteocytes in intact mouse long bones under dynamic mechanical loading. FASEB J 2013 1.00
48 Premenopausal and postmenopausal differences in bone microstructure and mechanical competence in Chinese-American and white women. J Bone Miner Res 2013 1.00
49 The generalized triphasic correspondence principle for simultaneous determination of the mechanical properties and proteoglycan content of articular cartilage by indentation. J Biomech 2007 0.99
50 Accuracy of high-resolution in vivo micro magnetic resonance imaging for measurements of microstructural and mechanical properties of human distal tibial bone. J Bone Miner Res 2010 0.99
51 Skeletal structure in postmenopausal women with osteopenia and fractures is characterized by abnormal trabecular plates and cortical thinning. J Bone Miner Res 2014 0.98
52 Bariatric surgery results in cortical bone loss. J Clin Endocrinol Metab 2013 0.98
53 Implications of resolution and noise for in vivo micro-MRI of trabecular bone. Med Phys 2008 0.97
54 Quasi-3D cytoskeletal dynamics of osteocytes under fluid flow. Biophys J 2010 0.97
55 Signaling through the M(3) muscarinic receptor favors bone mass accrual by decreasing sympathetic activity. Cell Metab 2010 0.96
56 Fluid Flow Induced Calcium Response in Bone Cell Network. Cell Mol Bioeng 2008 0.95
57 Teriparatide increases strength of the peripheral skeleton in premenopausal women with idiopathic osteoporosis: a pilot HR-pQCT study. J Clin Endocrinol Metab 2014 0.94
58 Geometric control of human stem cell morphology and differentiation. Integr Biol (Camb) 2010 0.94
59 Implications of noise and resolution on mechanical properties of trabecular bone estimated by image-based finite-element analysis. J Orthop Res 2009 0.94
60 Effects of thresholding techniques on microCT-based finite element models of trabecular bone. J Biomech Eng 2007 0.93
61 Abnormalities in cortical bone, trabecular plates, and stiffness in postmenopausal women treated with glucocorticoids. J Clin Endocrinol Metab 2014 0.93
62 Microarchitectural abnormalities are more severe in postmenopausal women with vertebral compared to nonvertebral fractures. J Clin Endocrinol Metab 2012 0.93
63 Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss. Curr Osteoporos Rep 2009 0.91
64 Matrix deposition modulates the viscoelastic shear properties of hydrogel-based cartilage grafts. Tissue Eng Part A 2011 0.90
65 The effect of matrix tension-compression nonlinearity and fixed negative charges on chondrocyte responses in cartilage. Mol Cell Biomech 2005 0.90
66 Contributions of trabecular rods of various orientations in determining the elastic properties of human vertebral trabecular bone. Bone 2009 0.88
67 FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin. J Clin Invest 2012 0.88
68 Spatiotemporal properties of intracellular calcium signaling in osteocytic and osteoblastic cell networks under fluid flow. Bone 2013 0.88
69 A Trabecular Bone Explant Model of Osteocyte-Osteoblast Co-Culture for Bone Mechanobiology. Cell Mol Bioeng 2009 0.88
70 Calcium Concentration Effects on the Mechanical and Biochemical Properties of Chondrocyte-Alginate Constructs. Cell Mol Bioeng 2008 0.87
71 Immune response and effect of adenovirus-mediated human BMP-2 gene transfer on the repair of segmental tibial bone defects in goats. Acta Orthop 2005 0.87
72 Skeletal microstructural abnormalities in postmenopausal women with chronic obstructive pulmonary disease. J Bone Miner Res 2010 0.86
73 Type and orientation of yielded trabeculae during overloading of trabecular bone along orthogonal directions. J Biomech 2010 0.86
74 Central QCT reveals lower volumetric BMD and stiffness in premenopausal women with idiopathic osteoporosis, regardless of fracture history. J Clin Endocrinol Metab 2012 0.85
75 Dynamic simulation of three dimensional architectural and mechanical alterations in human trabecular bone during menopause. Bone 2008 0.85
76 Bioactive stratified polymer ceramic-hydrogel scaffold for integrative osteochondral repair. Ann Biomed Eng 2010 0.84
77 In vivo evaluation of a tri-phasic composite scaffold for anterior cruciate ligament-to-bone integration. Conf Proc IEEE Eng Med Biol Soc 2006 0.84
78 Fast trabecular bone strength predictions of HR-pQCT and individual trabeculae segmentation-based plate and rod finite element model discriminate postmenopausal vertebral fractures. J Bone Miner Res 2013 0.84
79 Fixed electrical charges and mobile ions affect the measurable mechano-electrochemical properties of charged-hydrated biological tissues: the articular cartilage paradigm. Mech Chem Biosyst 2004 0.84
80 The impact of biomechanics in tissue engineering and regenerative medicine. Tissue Eng Part B Rev 2009 0.84
81 Simultaneous tracking of 3D actin and microtubule strains in individual MLO-Y4 osteocytes under oscillatory flow. Biochem Biophys Res Commun 2013 0.83
82 Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption. J Bone Miner Res 2011 0.83
83 A linearized formulation of triphasic mixture theory for articular cartilage, and its application to indentation analysis. J Biomech 2009 0.83
84 Interfacial strength of cement lines in human cortical bone. Mech Chem Biosyst 2005 0.83
85 Intercellular calcium wave propagation in linear and circuit-like bone cell networks. Philos Trans A Math Phys Eng Sci 2010 0.82
86 Lower cortical porosity and higher tissue mineral density in Chinese American versus white women. J Bone Miner Res 2014 0.82
87 Accuracy of individual trabecula segmentation based plate and rod finite element models in idealized trabecular bone microstructure. J Biomech Eng 2013 0.81
88 Analysis of microstructural and mechanical alterations of trabecular bone in a simulated three-dimensional remodeling process. J Biomech 2012 0.81
89 Quantification of trabecular bone microdamage using the virtual internal bond model and the individual trabeculae segmentation technique. Comput Methods Biomech Biomed Engin 2010 0.80
90 Spatially varying material properties of the rat caudal intervertebral disc. Spine (Phila Pa 1976) 2006 0.79
91 Spreading area and shape regulate apoptosis and differentiation of osteoblasts. Biomed Mater 2013 0.79
92 Localization and distribution of cartilage oligomeric matrix protein in the rat intervertebral disc. Spine (Phila Pa 1976) 2006 0.79
93 A triphasic orthotropic laminate model for cartilage curling behavior: fixed charge density versus mechanical properties inhomogeneity. J Biomech Eng 2010 0.78
94 Intervention timing of strontium treatment on estrogen depletion-induced osteoporosis in rats: bone microstructure and mechanics. J Orthop Res 2013 0.78
95 Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease. J Clin Invest 2016 0.78
96 Prediction of cortical bone elastic constants by a two-level micromechanical model using a generalized self-consistent method. J Biomech Eng 2006 0.77
97 Theoretical Analysis of Novel Quasi-3D Microscopy of Cell Deformation. Cell Mol Bioeng 2011 0.77
98 Osteocyte-viability-based simulations of trabecular bone loss and recovery in disuse and reloading. Biomech Model Mechanobiol 2013 0.76
99 A new fracture assessment approach coupling HR-pQCT imaging and fracture mechanics-based finite element modeling. J Biomech 2013 0.76
100 Cellular and Molecular Bioengineering: A Tipping Point. Cell Mol Bioeng 2012 0.75
101 Tissue Engineered Bone Differentiated From Human Adipose Derived Stem Cells Inhibit Posterolateral Fusion in an Athymic Rat Model. Spine (Phila Pa 1976) 2017 0.75
102 Multi-scale biothermal and biomechanical behaviours of biological materials. Philos Trans A Math Phys Eng Sci 2010 0.75
103 Geometric determinants to cement line debonding and osteonal lamellae failure in osteon pushout tests. J Biomech Eng 2004 0.75