PubRank

Erminio Costa

Author PubWeight™ 50.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Reelin promoter hypermethylation in schizophrenia. Proc Natl Acad Sci U S A 2005 3.12
2 Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis. Proc Natl Acad Sci U S A 2006 2.01
3 DNA methyltransferase inhibitors coordinately induce expression of the human reelin and glutamic acid decarboxylase 67 genes. Mol Pharmacol 2006 1.95
4 GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology (Berl) 2005 1.82
5 Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol Psychiatry 2005 1.74
6 In psychosis, cortical interneurons overexpress DNA-methyltransferase 1. Proc Natl Acad Sci U S A 2005 1.72
7 On the epigenetic regulation of the human reelin promoter. Nucleic Acids Res 2002 1.69
8 Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake. Psychopharmacology (Berl) 2006 1.48
9 A reelin-integrin receptor interaction regulates Arc mRNA translation in synaptoneurosomes. Proc Natl Acad Sci U S A 2003 1.38
10 Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophr Res 2007 1.34
11 The human reelin gene: transcription factors (+), repressors (-) and the methylation switch (+/-) in schizophrenia. Pharmacol Ther 2006 1.32
12 DNA methyltransferase 1 regulates reelin mRNA expression in mouse primary cortical cultures. Proc Natl Acad Sci U S A 2005 1.26
13 Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice. Proc Natl Acad Sci U S A 2007 1.23
14 Decreased corticolimbic allopregnanolone expression during social isolation enhances contextual fear: A model relevant for posttraumatic stress disorder. Proc Natl Acad Sci U S A 2008 1.22
15 Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population. Schizophr Res 2006 1.18
16 Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends Pharmacol Sci 2008 1.17
17 S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. Neuroreport 2007 1.17
18 Histone deacetylase inhibitors decrease reelin promoter methylation in vitro. J Neurochem 2005 1.16
19 SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake. Curr Opin Pharmacol 2009 1.15
20 In socially isolated mice, the reversal of brain allopregnanolone down-regulation mediates the anti-aggressive action of fluoxetine. Proc Natl Acad Sci U S A 2003 1.14
21 In Patas monkey, glutamic acid decarboxylase-67 and reelin mRNA coexpression varies in a manner dependent on layers and cortical areas. J Comp Neurol 2002 1.07
22 Neurosteroid biosynthesis regulates sexually dimorphic fear and aggressive behavior in mice. Neurochem Res 2008 1.03
23 Reelin down-regulation in mice and psychosis endophenotypes. Neurosci Biobehav Rev 2006 0.99
24 Social isolation stress-induced aggression in mice: a model to study the pharmacology of neurosteroidogenesis. Stress 2005 0.98
25 Olfactory discrimination learning deficit in heterozygous reeler mice. Brain Res 2003 0.98
26 Lower number of cerebellar Purkinje neurons in psychosis is associated with reduced reelin expression. Proc Natl Acad Sci U S A 2010 0.97
27 Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids. Proc Natl Acad Sci U S A 2004 0.95
28 Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior. Proc Natl Acad Sci U S A 2005 0.95
29 Chromatin, DNA methylation and neuron gene regulation--the purpose of the package. J Psychiatry Neurosci 2005 0.91
30 Imidazenil and diazepam increase locomotor activity in mice exposed to protracted social isolation. Proc Natl Acad Sci U S A 2006 0.91
31 Imidazenil, a non-sedating anticonvulsant benzodiazepine, is more potent than diazepam in protecting against DFP-induced seizures and neuronal damage. Toxicology 2008 0.88
32 Imidazenil: a low efficacy agonist at alpha1- but high efficacy at alpha5-GABAA receptors fail to show anticonvulsant cross tolerance to diazepam or zolpidem. Neuropharmacology 2008 0.87
33 Antipsychotic subtypes can be characterized by differences in their ability to modify GABAergic promoter methylation. Epigenomics 2009 0.84
34 The combination of huperzine A and imidazenil is an effective strategy to prevent diisopropyl fluorophosphate toxicity in mice. Proc Natl Acad Sci U S A 2008 0.84
35 Imidazenil: a potent and safe protective agent against diisopropyl fluorophosphate toxicity. Neuropharmacology 2004 0.83
36 Brain neurosteroids in gender-related aggression induced by social isolation. Crit Rev Neurobiol 2004 0.83
37 L-methionine decreases dendritic spine density in mouse frontal cortex. Neuroreport 2010 0.80
38 Acute imidazenil treatment after the onset of DFP-induced seizure is more effective and longer lasting than midazolam at preventing seizure activity and brain neuropathology. Toxicol Sci 2010 0.80
39 Should allosteric positive modulators of GABA(A) receptors be tested in the treatment of schizophrenia? Schizophr Res 2005 0.79
40 Anticonvulsant, anxiolytic, and non-sedating actions of imidazenil and other imidazo-benzodiazepine carboxamide derivatives. Pharmacol Biochem Behav 2010 0.79
41 Varenicline treatment decreases DNMT1 mRNA expression in lymphocytes of schizophrenic patients who are cigarette smokers. Schizophr Res 2010 0.77
42 Imidazenil: an antagonist of the sedative but not the anticonvulsant action of diazepam. Neuropharmacology 2005 0.76
43 [Stress and sleep/emotional disorder: possible involvement of neurosteroid allopregnanolone]. Nihon Yakurigaku Zasshi 2005 0.76