N Ratner

Author PubWeight™ 59.05‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Dev 1994 3.40
2 Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell 1992 3.30
3 The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling. Dev Cell 2001 2.89
4 Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes. Oncogene 1995 1.78
5 Epidermal growth factor receptor expression in neurofibromatosis type 1-related tumors and NF1 animal models. J Clin Invest 2000 1.56
6 Cognitive function and academic performance in neurofibromatosis. 1: consensus statement from the NF1 Cognitive Disorders Task Force. Neurology 1997 1.52
7 The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes. Neuron 1992 1.39
8 Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells. Oncogene 1998 1.38
9 CD44 enhances neuregulin signaling by Schwann cells. J Cell Biol 2000 1.38
10 Nf1-deficient mouse Schwann cells are angiogenic and invasive and can be induced to hyperproliferate: reversion of some phenotypes by an inhibitor of farnesyl protein transferase. Mol Cell Biol 1997 1.33
11 Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. J Biol Chem 2000 1.32
12 Angiogenic and invasive properties of neurofibroma Schwann cells. J Cell Biol 1990 1.28
13 A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation. J Cell Biol 1985 1.25
14 Schwann cell proliferative responses to cAMP and Nf1 are mediated by cyclin D1. J Neurosci 2001 1.24
15 cAMP-dependent protein kinase A is required for Schwann cell growth: interactions between the cAMP and neuregulin/tyrosine kinase pathways. J Neurosci Res 1997 1.18
16 The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells. Oncogene 2001 1.13
17 S100 is present in developing chicken neurons and Schwann cells and promotes motor neuron survival in vivo. J Neurobiol 1992 1.11
18 Inhibition of Eyes Absent Homolog 4 expression induces malignant peripheral nerve sheath tumor necrosis. Oncogene 2009 1.10
19 Neurofibromin, a predominantly neuronal GTPase activating protein in the adult, is ubiquitously expressed during development. Dev Dyn 1992 1.08
20 The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts. J Invest Dermatol 1999 1.06
21 PC12 cells as a source of neurite-derived cell surface mitogen, which stimulates Schwann cell division. J Cell Biol 1984 1.05
22 P0 is an early marker of the Schwann cell lineage in chickens. Neuron 1991 1.04
23 Games, social exchange and the acquisition of language. J Child Lang 1978 1.03
24 Hepatocyte growth factor is a mitogen for Schwann cells and is present in neurofibromas. J Neurosci 1994 1.02
25 Neurofibromin expression and astrogliosis in neurofibromatosis (type 1) brains. J Neuropathol Exp Neurol 1995 0.97
26 NF2-deficient cells depend on the Rac1-canonical Wnt signaling pathway to promote the loss of contact inhibition of proliferation. Oncogene 2010 0.97
27 Neurofibromin-deficient fibroblasts fail to form perineurium in vitro. Development 1995 0.97
28 Specific asparagine-linked oligosaccharides are not required for certain neuron-neuron and neuron-Schwann cell interactions. J Cell Biol 1986 0.96
29 Neurofibromin is enriched in the endoplasmic reticulum of CNS neurons. J Neurosci 1993 0.95
30 Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin. J Neurosci Res 2000 0.94
31 Schwann cells express NDF and SMDF/n-ARIA mRNAs, secrete neuregulin, and show constitutive activation of erbB3 receptors: evidence for a neuregulin autocrine loop. Exp Neurol 1997 0.93
32 Rubella virus: growth characteristics and stability of infectious virus and complement-fixing antigen. Proc Soc Exp Biol Med 1966 0.93
33 Region-specific astrogliosis in brains of mice heterozygous for mutations in the neurofibromatosis type 1 (Nf1) tumor suppressor. Brain Res 1999 0.89
34 The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice. J Invest Dermatol 2000 0.87
35 Neurofibromin, the neurofibromatosis type 1 Ras-GAP, is required for appropriate P0 expression and myelination. Ann N Y Acad Sci 1999 0.85
36 Structural organization of filamentous proteins in postsynaptic density. Biochemistry 1983 0.84
37 Localization of neurofibromin to keratinocytes and melanocytes in developing rat and human skin. J Invest Dermatol 1994 0.84
38 The NF2 tumor suppressor regulates microtubule-based vesicle trafficking via a novel Rac, MLK and p38(SAPK) pathway. Oncogene 2012 0.83
39 Identification and topography of synaptic phosphoproteins. Prog Brain Res 1982 0.82
40 Development of olfactory nerve glia defined by a monoclonal antibody specific for Schwann cells. Dev Dyn 1992 0.82
41 Axons arrest the migration of Schwann cell precursors. Development 1994 0.82
42 Expression of P30, a protein with adhesive properties, in Schwann cells and neurons of the developing and regenerating peripheral nerve. J Cell Biol 1991 0.81
43 Schwann cell proliferation in vitro. An overview. Ann N Y Acad Sci 1986 0.81
44 Advances in neurofibromatosis 2 (NF2): a workshop report. J Neurogenet 2000 0.80
45 Myelin glycoprotein P0 is expressed at early stages of chicken and rat embryogenesis. J Neurosci Res 1995 0.79
46 Amphoterin (P30, HMG-1) and RIP are early markers of oligodendrocytes in the developing rat spinal cord. J Neurocytol 1994 0.78
47 Immunocytochemical assay for Ras activity. Methods Enzymol 2001 0.77
48 Neuron-Schwann cell signals are conserved across species: purification and characterization of embryonic chicken Schwann cells. J Neurosci Res 1993 0.77
49 Schwann cells and cells in the oligodendrocyte lineage proliferate in response to a 50,000 dalton membrane-associated mitogen present in developing brain. Glia 1992 0.77
50 Regulation of neurofibromin expression in rat sciatic nerve and cultured Schwann cells. Glia 1995 0.77
51 Isolation of postsynaptic densities retaining their membrane attachment. Neuroscience 1983 0.77
52 Effect of transforming growth factor-beta 1 and -beta 2 on Schwann cell proliferation on neurites. Glia 1995 0.77
53 Ovarian hemangioma with acute abdominal pain. Mt Sinai J Med 1982 0.75
54 Overexpression of activated neu/erbB2 initiates immortalization and malignant transformation of immature Schwann cells in vitro. Oncogene 1999 0.75
55 Child care dilemma. Science 1988 0.75
56 A distinct splice form of APC is highly expressed in neurones but not commonly mutated in neuroepithelial tumours. J Med Genet 2001 0.75
57 [The importance of isotope nephrography and vasography in the diagnosis of renal hypertension]. Z Gesamte Inn Med 1966 0.75