Published in Structure on February 10, 2010
Spacer-length dependence of programmed -1 or -2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting. Nucleic Acids Res (2012) 0.94
Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use. Nucleic Acids Res (2016) 0.82
Human DNA tumor viruses generate alternative reading frame proteins through repeat sequence recoding. Proc Natl Acad Sci U S A (2014) 0.79
Structural Basis for Plexin Activation and Regulation. Neuron (2016) 0.75
Model of the pathway of -1 frameshifting: Long pausing. Biochem Biophys Rep (2016) 0.75
Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Crystallogr A (1991) 119.63
EMAN: semiautomated software for high-resolution single-particle reconstructions. J Struct Biol (1999) 27.52
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Structure of the 70S ribosome complexed with mRNA and tRNA. Science (2006) 12.25
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopy. J Mol Biol (2003) 12.04
Intermediate states in the movement of transfer RNA in the ribosome. Nature (1989) 7.30
Signals for ribosomal frameshifting in the Rous sarcoma virus gag-pol region. Cell (1988) 7.14
Characterization of an efficient coronavirus ribosomal frameshifting signal: requirement for an RNA pseudoknot. Cell (1989) 6.62
A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature (2000) 6.29
tRNA dynamics on the ribosome during translation. Proc Natl Acad Sci U S A (2004) 5.38
Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature (1997) 5.04
Crystal structure of a 70S ribosome-tRNA complex reveals functional interactions and rearrangements. Cell (2006) 4.90
mRNA helicase activity of the ribosome. Cell (2005) 4.72
Following translation by single ribosomes one codon at a time. Nature (2008) 4.14
Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. EMBO J (2004) 3.69
Dynamic reorganization of the functionally active ribosome explored by normal mode analysis and cryo-electron microscopy. Proc Natl Acad Sci U S A (2003) 3.64
Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J (2002) 3.57
The cryo-EM structure of a translation initiation complex from Escherichia coli. Cell (2005) 2.91
Translation elongation after assembly of ribosomes on the Cricket paralysis virus internal ribosomal entry site without initiation factors or initiator tRNA. Genes Dev (2003) 2.89
Kinetically competent intermediates in the translocation step of protein synthesis. Mol Cell (2007) 2.89
Architecture of the protein-conducting channel associated with the translating 80S ribosome. Cell (2001) 2.84
Ribosomal pausing during translation of an RNA pseudoknot. Mol Cell Biol (1993) 2.81
Normal mode based flexible fitting of high-resolution structure into low-resolution experimental data from cryo-EM. J Struct Biol (2004) 2.78
Structure of ratcheted ribosomes with tRNAs in hybrid states. Proc Natl Acad Sci U S A (2008) 2.77
Mutational analysis of the "slippery-sequence" component of a coronavirus ribosomal frameshifting signal. J Mol Biol (1992) 2.64
On the fitting of model electron densities into EM reconstructions: a reciprocal-space formulation. Acta Crystallogr D Biol Crystallogr (2002) 2.53
Structures of modified eEF2 80S ribosome complexes reveal the role of GTP hydrolysis in translocation. EMBO J (2007) 2.48
Enhanced translation of chimaeric messenger RNAs containing a plant viral untranslated leader sequence. Nature (1987) 2.47
A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting. Nature (2006) 2.41
The hybrid state of tRNA binding is an authentic translation elongation intermediate. Nat Struct Mol Biol (2006) 2.32
Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM. Nat Struct Mol Biol (2004) 2.27
Structure of the mammalian 80S ribosome at 8.7 A resolution. Structure (2008) 2.11
Viral RNA pseudoknots: versatile motifs in gene expression and replication. Nat Rev Microbiol (2007) 2.04
Ribosomal pausing at a frameshifter RNA pseudoknot is sensitive to reading phase but shows little correlation with frameshift efficiency. Mol Cell Biol (2001) 1.93
Translocation of tRNA during protein synthesis. FEBS Lett (2002) 1.85
Role and timing of GTP binding and hydrolysis during EF-G-dependent tRNA translocation on the ribosome. Proc Natl Acad Sci U S A (2006) 1.73
Two crystal structures demonstrate large conformational changes in the eukaryotic ribosomal translocase. Nat Struct Biol (2003) 1.69
Maintaining the ribosomal reading frame: the influence of the E site during translational regulation of release factor 2. Cell (2004) 1.68
Reverse translocation of tRNA in the ribosome. Mol Cell (2006) 1.59
Spontaneous reverse movement of mRNA-bound tRNA through the ribosome. Nat Struct Mol Biol (2007) 1.51
The A-site finger in 23 S rRNA acts as a functional attenuator for translocation. J Biol Chem (2006) 1.41
Characterization of the mechanical unfolding of RNA pseudoknots. J Mol Biol (2007) 1.20
The mechanics of translocation: a molecular "spring-and-ratchet" system. Structure (2008) 0.95
Reconfiguration of yeast 40S ribosomal subunit domains by the translation initiation multifactor complex. Proc Natl Acad Sci U S A (2007) 0.91
Hepatitis B small surface antigen particles are octahedral. Proc Natl Acad Sci U S A (2005) 1.25