ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain.

PubWeight™: 1.31‹?› | Rank: Top 10%

🔗 View Article (PMID 20159591)

Published in Dev Cell on February 16, 2010

Authors

Kristin D Kernohan1, Yan Jiang, Deanna C Tremblay, Anne C Bonvissuto, James H Eubanks, Mellissa R W Mann, Nathalie G Bérubé

Author Affiliations

1: Department of Paediatrics, 800 Commissioners Road East, London, ON N6C 2V5, Canada.

Articles citing this

Histone turnover and chromatin accessibility: Critical mediators of neurological development, plasticity, and disease. Bioessays (2016) 1.40

Genome-wide analysis reveals methyl-CpG-binding protein 2-dependent regulation of microRNAs in a mouse model of Rett syndrome. Proc Natl Acad Sci U S A (2010) 1.33

Phosphorylation of distinct sites in MeCP2 modifies cofactor associations and the dynamics of transcriptional regulation. Mol Cell Biol (2012) 1.20

Calcium-dependent dephosphorylation of the histone chaperone DAXX regulates H3.3 loading and transcription upon neuronal activation. Neuron (2012) 1.18

Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One (2011) 1.06

ATRX: the case of a peculiar chromatin remodeler. Epigenetics (2012) 1.03

The human imprintome: regulatory mechanisms, methods of ascertainment, and roles in disease susceptibility. ILAR J (2012) 0.99

ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes. Cell Rep (2015) 0.99

Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest (2013) 0.98

Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies. Biochim Biophys Acta (2013) 0.97

Nonallelic transcriptional roles of CTCF and cohesins at imprinted loci. Mol Cell Biol (2011) 0.96

In vitro assembly of physiological cohesin/DNA complexes. Proc Natl Acad Sci U S A (2011) 0.96

Atrx promotes heterochromatin formation at retrotransposons. EMBO Rep (2015) 0.94

The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture. Front Oncol (2013) 0.91

Epigenetic layers and players underlying neurodevelopment. Trends Neurosci (2013) 0.88

Alcohol and NMDA receptor: current research and future direction. Front Mol Neurosci (2013) 0.87

Improved transcription and translation with L-leucine stimulation of mTORC1 in Roberts syndrome. BMC Genomics (2016) 0.86

Role of ATRX in chromatin structure and function: implications for chromosome instability and human disease. Reproduction (2011) 0.86

ATRX tolerates activity-dependent histone H3 methyl/phos switching to maintain repetitive element silencing in neurons. Proc Natl Acad Sci U S A (2014) 0.85

XNP/dATRX interacts with DREF in the chromatin to regulate gene expression. Nucleic Acids Res (2011) 0.85

The CENP-A nucleosome: a battle between Dr Jekyll and Mr Hyde. Nucleus (2013) 0.85

Cohesin: a critical chromatin organizer in mammalian gene regulation. Biochem Cell Biol (2011) 0.84

Autism genes keep turning up chromatin. OA Autism (2013) 0.84

How hard is the CNS hardware? Nat Neurosci (2010) 0.83

Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping. Nucleic Acids Res (2014) 0.83

Viral reprogramming of the Daxx histone H3.3 chaperone during early Epstein-Barr virus infection. J Virol (2014) 0.83

The roles of cohesins in mitosis, meiosis, and human health and disease. Methods Mol Biol (2014) 0.82

Genetic Inactivation of ATRX Leads to a Decrease in the Amount of Telomeric Cohesin and Level of Telomere Transcription in Human Glioma Cells. Mol Cell Biol (2015) 0.80

The epigenetics of stroke recovery and rehabilitation: from polycomb to histone deacetylases. Neurotherapeutics (2013) 0.80

Role of mecp2 in experience-dependent epigenetic programming. Genes (Basel) (2015) 0.79

Matters of life and death: the role of chromatin remodeling proteins in retinal neuron survival. J Ocul Biol Dis Infor (2012) 0.79

Chromatin modifiers, cognitive disorders, and imprinted genes. Dev Cell (2010) 0.78

Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors. Horm Cancer (2013) 0.77

A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement. PLoS One (2013) 0.76

Imprinted Zac1 in neural stem cells. World J Stem Cells (2015) 0.76

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome. PLoS Genet (2016) 0.76

Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome. Epigenetics Chromatin (2017) 0.75

MeCP2-Related Diseases and Animal Models. Diseases (2014) 0.75

Structural maintenance of chromosome complexes and bone development: the beginning of a wonderful relationship? Bonekey Rep (2013) 0.75

ERCC1-XPF cooperates with CTCF and cohesin to facilitate the developmental silencing of imprinted genes. Nat Cell Biol (2017) 0.75

Structural Variant Detection by Large-scale Sequencing Reveals New Evolutionary Evidence on Breed Divergence between Chinese and European Pigs. Sci Rep (2016) 0.75

MECP2 expression in gastric cancer and its correlation with clinical pathological parameters. Medicine (Baltimore) (2017) 0.75

Articles by these authors

Genome dynamics and diversity of Shigella species, the etiologic agents of bacillary dysentery. Nucleic Acids Res (2005) 3.56

The changing face of HIV in China. Nature (2008) 3.39

Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity (2012) 2.47

Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis (2005) 2.44

Emergence of NDM-1-producing Acinetobacter baumannii in China. J Antimicrob Chemother (2011) 2.39

Co-infection with HIV and hepatitis C virus in former plasma/blood donors: challenge for patient care in rural China. AIDS (2006) 2.36

Novel genetic environment of the carbapenem-hydrolyzing beta-lactamase KPC-2 among Enterobacteriaceae in China. Antimicrob Agents Chemother (2009) 2.33

Genomic imprinting: intricacies of epigenetic regulation in clusters. Annu Rev Cell Dev Biol (2003) 2.26

Gene-specific timing and epigenetic memory in oocyte imprinting. Hum Mol Genet (2004) 2.25

HIV and syphilis prevalence among men who have sex with men: a cross-sectional survey of 61 cities in China. Clin Infect Dis (2013) 2.24

The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol (2012) 2.11

DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages. Development (2006) 2.08

Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc Natl Acad Sci U S A (2010) 2.06

Loss of ATRX leads to chromosome cohesion and congression defects. J Cell Biol (2008) 1.79

Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning. Proc Natl Acad Sci U S A (2003) 1.73

The retinoblastoma protein regulates pericentric heterochromatin. Mol Cell Biol (2006) 1.68

Preclinical research in Rett syndrome: setting the foundation for translational success. Dis Model Mech (2012) 1.66

Dual effects of superovulation: loss of maternal and paternal imprinted methylation in a dose-dependent manner. Hum Mol Genet (2010) 1.59

Characterization of ST-4821 complex, a unique Neisseria meningitidis clone. Genomics (2007) 1.59

The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells. J Neurobiol (2003) 1.58

Quantum teleportation and entanglement distribution over 100-kilometre free-space channels. Nature (2012) 1.56

The MeCP2-null mouse hippocampus displays altered basal inhibitory rhythms and is prone to hyperexcitability. Hippocampus (2008) 1.53

Tetraethyl 2,2'-(2,3,5,6-tetrafluoro-p-phenylenedimethylene)dipropanoate. Acta Crystallogr Sect E Struct Rep Online (2008) 1.53

Loss of genomic imprinting in mouse embryos with fast rates of preimplantation development in culture. Biol Reprod (2012) 1.50

Complete genome sequence of bacteriophage T5. Virology (2005) 1.48

Intrinsic left atrial histoanatomy as the basis for reentrant excitation causing atrial fibrillation/flutter in rats. Heart Rhythm (2013) 1.46

Chromatin immunoprecipitation in postmortem brain. J Neurosci Methods (2006) 1.43

Deficiency of PPARbeta/delta in the epidermis results in defective cutaneous permeability barrier homeostasis and increased inflammation. J Invest Dermatol (2007) 1.41

1,1,3-Trimethyl-3-phenyl-indane. Acta Crystallogr Sect E Struct Rep Online (2008) 1.41

Hypoxia induces epithelial-mesenchymal transition via activation of SNAI1 by hypoxia-inducible factor -1α in hepatocellular carcinoma. BMC Cancer (2013) 1.40

Complete nucleotide sequence of pKP96, a 67 850 bp multiresistance plasmid encoding qnrA1, aac(6')-Ib-cr and blaCTX-M-24 from Klebsiella pneumoniae. J Antimicrob Chemother (2008) 1.40

Analysis of homeostasis model assessment-insulin resistance HOMA-IR in healthy young Chinese adults. Saudi Med J (2010) 1.38

Epidemiological characteristics and genetic structure of blaNDM-1 in non-baumannii Acinetobacter spp. in China. J Antimicrob Chemother (2012) 1.36

X chromosome reactivation and regulation in cloned embryos. Dev Biol (2005) 1.34

Rapidly increasing rates of hip fracture in Beijing, China. J Bone Miner Res (2012) 1.30

Estimation of HIV-1 incidence among five focal populations in Dehong, Yunnan: a hard hit area along a major drug trafficking route. BMC Public Health (2010) 1.23

AtECB2, a pentatricopeptide repeat protein, is required for chloroplast transcript accD RNA editing and early chloroplast biogenesis in Arabidopsis thaliana. Plant J (2009) 1.22

Cell cycle- and apoptosis-regulatory protein-1 is involved in apoptosis signaling by epidermal growth factor receptor. J Biol Chem (2006) 1.22

Suspended moxibustion relieves chronic visceral hyperalgesia via serotonin pathway in the colon. Neurosci Lett (2008) 1.21

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice. Hum Mol Genet (2008) 1.19

Analysis of sequence upstream of the endogenous H19 gene reveals elements both essential and dispensable for imprinting. Mol Cell Biol (2002) 1.19

Increased dendritic complexity and axonal length in cultured mouse cortical neurons overexpressing methyl-CpG-binding protein MeCP2. Neurobiol Dis (2005) 1.19

1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes. J Steroid Biochem Mol Biol (2008) 1.19

Quantitative detection of HIV-1 RNA using NucliSens EasyQ HIV-1 assay. J Virol Methods (2005) 1.16

Early infant human immunodeficiency virus type 1 detection suitable for resource-limited settings with multiple circulating subtypes by use of nested three-monoplex DNA PCR and dried blood spots. J Clin Microbiol (2007) 1.16

The PcG gene Sfmbt2 is paternally expressed in extraembryonic tissues. Gene Expr Patterns (2007) 1.14

Repeated exposure to propofol potentiates neuroapoptosis and long-term behavioral deficits in neonatal rats. Neurosci Lett (2013) 1.13

HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China. Int J Infect Dis (2007) 1.13

Wide distribution of CC92 carbapenem-resistant and OXA-23-producing Acinetobacter baumannii in multiple provinces of China. Int J Antimicrob Agents (2013) 1.12

Multiple epigenetic modifiers induce aggressive viral extinction in extraembryonic endoderm stem cells. Cell Stem Cell (2010) 1.11

Breeding and maintenance of an Mecp2-deficient mouse model of Rett syndrome. J Neurosci Methods (2006) 1.10

High-average-power 2-kHz laser for generation of ultrashort x-ray pulses. Opt Lett (2002) 1.09

Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids. Nature (2012) 1.09

Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter. Am J Physiol Gastrointest Liver Physiol (2002) 1.08

Alterations of cortical and hippocampal EEG activity in MeCP2-deficient mice. Neurobiol Dis (2010) 1.08

The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome. Hum Mol Genet (2012) 1.06

Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver. Drug Metab Dispos (2009) 1.06

Seroincidence of recent human immunodeficiency virus type 1 infections in China. Clin Vaccine Immunol (2007) 1.06

Domain-specific response of imprinted genes to reduced DNMT1. Mol Cell Biol (2010) 1.05

Effect of transglutaminase treatment on the properties of cast films of soy protein isolates. J Biotechnol (2005) 1.05

Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cells. Hum Reprod Update (2010) 1.04

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Mol Syst Biol (2013) 1.03

An analysis of high glucose and glucosamine-induced gene expression and oxidative stress in renal mesangial cells. Arch Physiol Biochem (2006) 1.02

A noninterference polypyrrole glucose biosensor. Biosens Bioelectron (2006) 1.01

Transcriptional regulators of chondrocyte hypertrophy. Birth Defects Res C Embryo Today (2008) 1.01

Down-regulation of CD9 expression during prostate carcinoma progression is associated with CD9 mRNA modifications. Clin Cancer Res (2007) 1.01

A novel cost-effective technology to convert sucrose and homocelluloses in sweet sorghum stalks into ethanol. Biotechnol Biofuels (2013) 1.01

Human immunodeficiency virus-1 genotypic drug resistance among volunteer blood donors in Yunnan, China. Transfusion (2009) 1.00

Identification of KPC-2-producing Pseudomonas aeruginosa isolates in China. J Antimicrob Chemother (2011) 1.00

Embryonic imprinting perturbations do not originate from superovulation-induced defects in DNA methylation acquisition. Fertil Steril (2011) 0.99

Increased osteopontin contributes to inhibition of bone mineralization in FGF23-deficient mice. J Bone Miner Res (2014) 0.99

Demographic characteristics and risk behaviors associated with HIV positive injecting drug users in Xinjiang, China. J Infect (2006) 0.99

Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest (2013) 0.98

Cx43 contributes to TGF-beta signaling to regulate differentiation of cardiac fibroblasts into myofibroblasts. Exp Cell Res (2009) 0.98

Child body mass index in four cities of East China compared to Western references. Ann Hum Biol (2008) 0.98

Drug use and sex work: competing risk factors for newly acquired HIV in Yunnan, China. PLoS One (2013) 0.96

Genomic imprints as a model for the analysis of epigenetic stability during assisted reproductive technologies. Reproduction (2012) 0.96

Cloning and functional identification of two members of the ZIP (Zrt, Irt-like protein) gene family in rice (Oryza sativa L.). Mol Biol Rep (2007) 0.96

Complete genome sequence of the extremophilic Bacillus cereus strain Q1 with industrial applications. J Bacteriol (2008) 0.96

Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci (2008) 0.96

Aminoglycoside-mediated partial suppression of MECP2 nonsense mutations responsible for Rett syndrome in vitro. J Neurosci Res (2010) 0.95

The levels of bone turnover markers in Chinese postmenopausal women: Peking Vertebral Fracture study. Menopause (2011) 0.94

Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells. Development (2011) 0.94

Polyacrylamide hydrogel injection for breast augmentation: another injectable failure. Med Sci Monit (2012) 0.94

Probing single biomolecules in solution using the anti-Brownian electrokinetic (ABEL) trap. Acc Chem Res (2012) 0.94

Risk factors for development of new-onset diabetes mellitus in adult heart transplant recipients. Transplantation (2010) 0.93

Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic kappa1 immunoglobulin light chains. Biochemistry (2007) 0.93

LPS-induced epithelial-mesenchymal transition of intrahepatic biliary epithelial cells. J Surg Res (2010) 0.92

Body mass index, waist circumference, and cardiometabolic risk factors in young and middle-aged Chinese women. J Zhejiang Univ Sci B (2010) 0.92

Roles of Fyn in pancreatic cancer metastasis. J Gastroenterol Hepatol (2009) 0.92

Blocking effects of siRNA on VEGF expression in human colorectal cancer cells. World J Gastroenterol (2010) 0.92

YY1 associates with the macrosatellite DXZ4 on the inactive X chromosome and binds with CTCF to a hypomethylated form in some male carcinomas. Nucleic Acids Res (2011) 0.92

[Surveillance on HIV-1 incidence among men who have sex with men in Chongqing, China, 2006 - 2008]. Zhonghua Liu Xing Bing Xue Za Zhi (2009) 0.92

Expression analysis of rice A20/AN1-type zinc finger genes and characterization of ZFP177 that contributes to temperature stress tolerance. Gene (2008) 0.91

Cloud point extraction for high-performance liquid chromatographic speciation of Cr(III) and Cr(VI) in aqueous solutions. J Chromatogr A (2004) 0.91

Nuclear-cytoplasmic "tug of war" during cloning: effects of somatic cell nuclei on culture medium preferences of preimplantation cloned mouse embryos. Biol Reprod (2002) 0.91

Photokilling cancer cells using highly cell-specific antibody-TiO(2) bioconjugates and electroporation. Bioelectrochemistry (2007) 0.91