Published in Nucleic Acids Res on July 02, 2014
Histone turnover and chromatin accessibility: Critical mediators of neurological development, plasticity, and disease. Bioessays (2016) 1.40
MECP2 disorders: from the clinic to mice and back. J Clin Invest (2015) 1.02
ATRX Plays a Key Role in Maintaining Silencing at Interstitial Heterochromatic Loci and Imprinted Genes. Cell Rep (2015) 0.99
Spatial genome organization and cognition. Nat Rev Neurosci (2016) 0.78
A novel MeCP2 acetylation site regulates interaction with ATRX and HDAC1. Genes Cancer (2015) 0.78
Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome. Epigenetics Chromatin (2017) 0.75
82-kDa choline acetyltransferase and SATB1 localize to β-amyloid induced matrix attachment regions. Sci Rep (2016) 0.75
MeCP2, a key contributor to neurological disease, activates and represses transcription. Science (2008) 10.11
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet (2006) 8.99
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79
MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell (1997) 6.45
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2. Proc Natl Acad Sci U S A (2006) 5.95
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome. Nat Genet (2004) 5.64
The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome. PLoS Genet (2008) 4.91
CTCF physically links cohesin to chromatin. Proc Natl Acad Sci U S A (2008) 4.89
Single-cell Hi-C reveals cell-to-cell variability in chromosome structure. Nature (2013) 4.47
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell (2010) 4.34
Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc Natl Acad Sci U S A (2007) 4.00
Zac1 regulates an imprinted gene network critically involved in the control of embryonic growth. Dev Cell (2006) 3.67
The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies. Proc Natl Acad Sci U S A (2003) 3.52
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res (2010) 3.46
Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus. PLoS Genet (2009) 3.25
Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome). Cell (1995) 3.09
Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression. EMBO J (2007) 2.99
PcG proteins, DNA methylation, and gene repression by chromatin looping. PLoS Biol (2008) 2.85
The role of MeCP2 in the brain. Annu Rev Cell Dev Biol (2011) 2.84
CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loop. Mol Cell Biol (2008) 2.24
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. J Biol Chem (2004) 1.98
Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules. Genome Res (2012) 1.95
Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation. Proc Natl Acad Sci U S A (2007) 1.84
The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription. Mol Cell (2008) 1.81
CTCF binding and higher order chromatin structure of the H19 locus are maintained in mitotic chromatin. EMBO J (2005) 1.81
Loss of ATRX leads to chromosome cohesion and congression defects. J Cell Biol (2008) 1.79
The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis. J Clin Invest (2005) 1.74
X-linked alpha-thalassemia/mental retardation (ATR-X) syndrome: localization to Xq12-q21.31 by X inactivation and linkage analysis. Am J Hum Genet (1992) 1.72
Nonallelic transvection of multiple imprinted loci is organized by the H19 imprinting control region during germline development. Genes Dev (2009) 1.68
The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9. Hum Mol Genet (2011) 1.67
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. Dev Biol (2004) 1.60
An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs. Am J Physiol Regul Integr Comp Physiol (2008) 1.56
Multiple nucleosome positioning sites regulate the CTCF-mediated insulator function of the H19 imprinting control region. Mol Cell Biol (2002) 1.49
An AT-hook domain in MeCP2 determines the clinical course of Rett syndrome and related disorders. Cell (2013) 1.49
Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX. Proc Natl Acad Sci U S A (2007) 1.45
CTCF is the master organizer of domain-wide allele-specific chromatin at the H19/Igf2 imprinted region. Mol Cell Biol (2007) 1.38
ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain. Dev Cell (2010) 1.31
Tandem repeats in the CpG islands of imprinted genes. Genomics (2006) 1.31
Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences. Nucleic Acids Res (2006) 1.26
Methods for identifying higher-order chromatin structure. Annu Rev Genomics Hum Genet (2012) 1.15
Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains. Mamm Genome (1998) 1.13
DLX5 and DLX6 expression is biallelic and not modulated by MeCP2 deficiency. Am J Hum Genet (2007) 1.13
A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele. Mol Endocrinol (2008) 1.12
ATR-X mutations cause impaired nuclear location and altered DNA binding properties of the XNP/ATR-X protein. J Med Genet (2000) 1.07
ATRX: the case of a peculiar chromatin remodeler. Epigenetics (2012) 1.03
De novo mutations in the genome organizer CTCF cause intellectual disability. Am J Hum Genet (2013) 1.01
ANOVA-like differential expression (ALDEx) analysis for mixed population RNA-Seq. PLoS One (2013) 0.99
Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress. J Biol Chem (2013) 0.98
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest (2013) 0.98
Functional significance of mutations in the Snf2 domain of ATRX. Hum Mol Genet (2011) 0.96
Detecting long-range chromatin interactions using the chromosome conformation capture sequencing (4C-seq) method. Methods Mol Biol (2012) 0.93
Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet (2011) 0.92
Compromised genomic integrity impedes muscle growth after Atrx inactivation. J Clin Invest (2012) 0.92
Expression analysis and mutation detection of DLX5 and DLX6 in autism. Brain Dev (2009) 0.92
Genomic matrix attachment region and chromosome conformation capture quantitative real time PCR assays identify novel putative regulatory elements at the imprinted Dlk1/Gtl2 locus. J Biol Chem (2008) 0.91
Syndromal mental retardation due to mutations in a regulator of gene expression. Hum Mol Genet (1995) 0.89
Genetic and epigenetic dysregulation of imprinted genes in the brain. Epigenomics (2010) 0.88
ATRX in chromatin assembly and genome architecture during development and disease. Biochem Cell Biol (2011) 0.86
DLX5 expression is monoallelic and Dlx5 is up-regulated in the Mecp2-null frontal cortex. J Cell Mol Med (2008) 0.84
CTCF-binding sites within the H19 ICR differentially regulate local chromatin structures and cis-acting functions. Epigenetics (2012) 0.82
Temporal and spatial expression of a growth-regulated network of imprinted genes in growth plate. Pediatr Nephrol (2009) 0.80
The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in the mouse genome. BMC Genomics (2008) 0.77