Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate.

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Published in J Clin Oncol on February 16, 2010

Authors

Alison H M Reid1, Gerhardt Attard, Daniel C Danila, Nikhil Babu Oommen, David Olmos, Peter C Fong, L Rhoda Molife, Joanne Hunt, Christina Messiou, Christopher Parker, David Dearnaley, Joost F Swennenhuis, Leon W M M Terstappen, Gloria Lee, Thian Kheoh, Arturo Molina, Charles J Ryan, Eric Small, Howard I Scher, Johann S de Bono

Author Affiliations

1: The Institute of Cancer Research, The Royal Marsden NHS Foundation Trust, Sutton, Surrey, UK. johann.de-bono@icr.ac.uk

Associated clinical trials:

Abiraterone Acetate in Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy | NCT00638690

An Safety and Efficacy Study of Abiraterone Acetate in Participants With Advanced Prostate Cancer Who Failed Androgen Deprivation and Docetaxel-Based Chemotherapy | NCT00474383

Study of Abiraterone Acetate Plus ADT Versus APALUTAMIDE Versus Abiraterone and APALUTAMIDE in Patients With Advanced Prostate Cancer With Non-castrate Testosterone Levels | NCT02867020

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