Published in J Clin Pharmacol on February 16, 2010
Pharmacokinetics, metabolism and excretion of [(14)C]-lenalidomide following oral administration in healthy male subjects. Cancer Chemother Pharmacol (2011) 1.06
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Lenalidomide at therapeutic and supratherapeutic doses does not prolong QTc intervals in the thorough QTc study conducted in healthy men. Basic Clin Pharmacol Toxicol (2013) 0.83
Pharmacokinetics and tissue disposition of lenalidomide in mice. AAPS J (2012) 0.80
Use of lenalidomide in the management of relapsed or refractory multiple myeloma: expert recommendations in Korea. Blood Res (2015) 0.79
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An energy-aware routing protocol in wireless sensor networks. Sensors (Basel) (2009) 11.25
Pharmacokinetics of lenalidomide in subjects with various degrees of renal impairment and in subjects on hemodialysis. J Clin Pharmacol (2007) 1.89
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Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation (2009) 1.71
Lenalidomide plus dexamethasone treatment in Japanese patients with relapsed/refractory multiple myeloma. Int J Hematol (2010) 1.63
Randomized phase II trial of lyophilized strawberries in patients with dysplastic precancerous lesions of the esophagus. Cancer Prev Res (Phila) (2011) 1.53
Cutaneous ciliated cyst of the abdominal wall: a case report with a review of the literature and discussion of pathogenesis. Am J Dermatopathol (2002) 1.52
Prevalence of porcine circovirus-like agent P1 in Jiangsu, China. Virol J (2011) 1.35
Evaluation of the developmental toxicity of lenalidomide in rabbits. Birth Defects Res B Dev Reprod Toxicol (2007) 1.22
Preclinical pharmacokinetic/pharmacodynamic models of gefitinib and the design of equivalent dosing regimens in EGFR wild-type and mutant tumor models. Mol Cancer Ther (2008) 1.20
Syk associates with clathrin and mediates phosphatidylinositol 3-kinase activation during human rhinovirus internalization. J Immunol (2008) 1.14
Mechanisms of signal transduction by ethylene: overlapping and non-overlapping signalling roles in a receptor family. AoB Plants (2013) 1.14
Stem cells from human-exfoliated deciduous teeth can differentiate into dopaminergic neuron-like cells. Stem Cells Dev (2010) 1.13
Cardiac-targeted RNA interference mediated by an AAV9 vector improves cardiac function in coxsackievirus B3 cardiomyopathy. J Mol Med (Berl) (2008) 1.13
Complete genome sequence of a recombinant porcine epidemic diarrhea virus strain from eastern china. Genome Announc (2013) 1.12
TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation. J Immunol (2013) 1.11
Complete genome sequence of the rearranged porcine circovirus type 2. J Virol (2012) 1.10
Predicting human tumor drug concentrations from a preclinical pharmacokinetic model of temozolomide brain disposition. Clin Cancer Res (2007) 1.10
Dedifferentiation of adult human myoblasts induced by ciliary neurotrophic factor in vitro. Mol Biol Cell (2005) 1.09
Triptolide inhibits COX-2 expression and PGE2 release by suppressing the activity of NF-kappaB and JNK in LPS-treated microglia. J Neurochem (2008) 1.09
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Development of a highly metastatic model that reveals a crucial role of fibronectin in lung cancer cell migration and invasion. BMC Cancer (2010) 1.07
Pharmacokinetics, metabolism and excretion of [(14)C]-lenalidomide following oral administration in healthy male subjects. Cancer Chemother Pharmacol (2011) 1.06
CalS7 encodes a callose synthase responsible for callose deposition in the phloem. Plant J (2010) 1.04
Leukocyte elastase induces epithelial apoptosis: role of mitochondial permeability changes and Akt. Am J Physiol Gastrointest Liver Physiol (2004) 1.03
Activated hepatic stellate cells promote hepatocellular carcinoma development in immunocompetent mice. Int J Cancer (2011) 1.03
Changes in the solubility and phosphorylation of α-synuclein over the course of Parkinson's disease. Acta Neuropathol (2011) 1.03
CD44 is a phagocytic receptor. Blood (2006) 1.03
Minimum expected delay-based routing protocol (MEDR) for Delay Tolerant Mobile Sensor Networks. Sensors (Basel) (2010) 1.02
A novel porcine circovirus-like agent P1 is associated with wasting syndromes in pigs. PLoS One (2012) 1.02
The antioxidative effect of electro-acupuncture in a mouse model of Parkinson's disease. PLoS One (2011) 1.02
A multiphase model of the dynamics of HBV infection in HBeAg-negative patients during pegylated interferon-alpha2a, lamivudine and combination therapy. Antivir Ther (2006) 1.01
Triptolide inhibits amyloid-beta1-42-induced TNF-alpha and IL-1beta production in cultured rat microglia. J Neuroimmunol (2008) 1.00
Ethylene and nitric oxide are involved in maintaining ion homeostasis in Arabidopsis callus under salt stress. Planta (2009) 0.99
Safety, pharmacokinetics, and immunomodulatory effects of lenalidomide in children and adolescents with relapsed/refractory solid tumors or myelodysplastic syndrome: a Children's Oncology Group Phase I Consortium report. J Clin Oncol (2010) 0.99
Fucoidan protects against dopaminergic neuron death in vivo and in vitro. Eur J Pharmacol (2009) 0.99
Prevention of cardiac dysfunction in acute coxsackievirus B3 cardiomyopathy by inducible expression of a soluble coxsackievirus-adenovirus receptor. Circulation (2009) 0.98
Enteric-coated mycophenolate sodium delivers bioequivalent MPA exposure compared with mycophenolate mofetil. Clin Transplant (2005) 0.98
Lenalidomide: in vitro evaluation of the metabolism and assessment of cytochrome P450 inhibition and induction. Cancer Chemother Pharmacol (2008) 0.97
Amyloid-β induces caspase-dependent loss of PSD-95 and synaptophysin through NMDA receptors. J Alzheimers Dis (2010) 0.97
Induction of coxsackievirus-adenovirus-receptor expression during myocardial tissue formation and remodeling: identification of a cell-to-cell contact-dependent regulatory mechanism. Circulation (2003) 0.97
Neferine, a bisbenzylisoquinline alkaloid attenuates bleomycin-induced pulmonary fibrosis. Eur J Pharmacol (2009) 0.95
A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells. Oncol Rep (2011) 0.95
Autoimmune hepatitis following infliximab therapy for ankylosing spondylitis. Med J Aust (2007) 0.95
In vitro intragenomic rearrangement of porcine circovirus type 2. J Virol (2012) 0.95
A distance-aware replica adaptive data gathering protocol for Delay Tolerant Mobile Sensor Networks. Sensors (Basel) (2011) 0.95
Preclinical pharmacokinetic and pharmacodynamic evaluation of metronomic and conventional temozolomide dosing regimens. J Pharmacol Exp Ther (2007) 0.94
Effects of interleukin-6, leukemia inhibitory factor, and ciliary neurotrophic factor on the proliferation and differentiation of adult human myoblasts. Cell Mol Neurobiol (2008) 0.93
Serum levels of variants of transthyretin down-regulation in cholangiocarcinoma. J Cell Biochem (2008) 0.93
Precise and long-term tracking of adipose-derived stem cells and their regenerative capacity via superb bright and stable organic nanodots. ACS Nano (2014) 0.93
Gadd45a regulates hematopoietic stem cell stress responses in mice. Blood (2013) 0.92
Transdermal delivery of nonsteroidal anti-inflammatory drugs mediated by polyamidoamine (PAMAM) dendrimers. J Pharm Sci (2007) 0.92
Determination of methotrexate and its major metabolite 7-hydroxymethotrexate in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal (2007) 0.92
18β-glycyrrhetinic acid inhibits hepatocellular carcinoma development by reversing hepatic stellate cell-mediated immunosuppression in mice. Int J Cancer (2012) 0.92
Reduced transthyretin expression in sera of lung cancer. Cancer Sci (2007) 0.91
Complete genome sequence of a highly prevalent porcine circovirus 2 isolated from piglet stool samples in China. J Virol (2012) 0.91
Silica-based monolithic sensing plates for waveguide-mode sensors. Opt Express (2008) 0.91
Matricellular signaling molecule CCN1 attenuates experimental autoimmune myocarditis by acting as a novel immune cell migration modulator. Circulation (2010) 0.91
Sema4C participates in myogenic differentiation in vivo and in vitro through the p38 MAPK pathway. Eur J Cell Biol (2007) 0.90
Engineered iron-oxide-based nanoparticles as enhanced T1 contrast agents for efficient tumor imaging. ACS Nano (2013) 0.89
Leptin induces cell proliferation and reduces cell apoptosis by activating c-myc in cervical cancer. Oncol Rep (2013) 0.89
Precocious pollen germination in Arabidopsis plants with altered callose deposition during microsporogenesis. Planta (2009) 0.89
Development of a novel TaqMan-based real-time PCR assay for the detection of porcine boca-like virus (Pbo-likeV). Virol J (2011) 0.89
Detection of colored nanomaterials using evanescent field-based waveguide sensors. Opt Express (2010) 0.89
Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats. Brain Res Bull (2011) 0.89
Attenuation of streptozotocin-induced diabetic retinopathy with low molecular weight fucoidan via inhibition of vascular endothelial growth factor. Exp Eye Res (2013) 0.89
AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model. Exp Neurol (2013) 0.88
Distinct efficacy of pre-differentiated versus intact fetal mesencephalon-derived human neural progenitor cells in alleviating rat model of Parkinson's disease. Int J Dev Neurosci (2004) 0.88
HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells. Neurosci Lett (2009) 0.88
In vitro and in vivo isolation of a novel rearranged porcine circovirus type 2. J Virol (2012) 0.88
Glucose-6-phosphate dehydrogenase plays a pivotal role in tolerance to drought stress in soybean roots. Plant Cell Rep (2012) 0.88
cGMP regulates hydrogen peroxide accumulation in calcium-dependent salt resistance pathway in Arabidopsis thaliana roots. Planta (2011) 0.87
Porcine reproductive and respiratory syndrome virus ORF5a protein is essential for virus viability. Virus Res (2012) 0.87
Retargeting NK-92 for anti-melanoma activity by a TCR-like single-domain antibody. Immunol Cell Biol (2013) 0.87
Nitric oxide enhances aluminum tolerance by affecting cell wall polysaccharides in rice roots. Plant Cell Rep (2011) 0.86
Involvement of receptor tyrosine kinase Tyro3 in amyloidogenic APP processing and β-amyloid deposition in Alzheimer's disease models. PLoS One (2012) 0.86
Effect of honghua (Flos Carthami) on nitric oxide production in RAW 264.7 cells and alpha-glucosidase activity. J Tradit Chin Med (2014) 0.86
Hypoxia promotes dopaminergic differentiation of mesenchymal stem cells and shows benefits for transplantation in a rat model of Parkinson's disease. PLoS One (2013) 0.86
Novel anti-inflammatory and neuroprotective agents for Parkinson's disease. CNS Neurol Disord Drug Targets (2010) 0.86
Viral and nonviral factors causing nonspecific replication of tumor- and tissue-specific promoter-dependent oncolytic adenoviruses. Mol Ther (2005) 0.85
Electro-acupuncture stimulation improves spontaneous locomotor hyperactivity in MPTP intoxicated mice. PLoS One (2013) 0.85
Tunable T1 and T2 contrast abilities of manganese-engineered iron oxide nanoparticles through size control. Nanoscale (2014) 0.85
Activations of nPKCepsilon and ERK1/2 were involved in oxygen-glucose deprivation-induced neuroprotection via NMDA receptors in hippocampal slices of mice. J Neurosurg Anesthesiol (2007) 0.85
Doxorubicin augments rAAV-2 transduction in rat neuronal cells. Neurochem Int (2009) 0.85
Small kernel 1 encodes a pentatricopeptide repeat protein required for mitochondrial nad7 transcript editing and seed development in maize (Zea mays) and rice (Oryza sativa). Plant J (2014) 0.85
An improved Tet-On regulatable FasL-adenovirus vector system for lung cancer therapy. J Mol Med (Berl) (2005) 0.85
Critical role of L-type voltage-dependent Ca2+ channels in neural progenitor cell proliferation induced by hypoxia. Neurosci Lett (2010) 0.85
Nitric oxide protects against polyethylene glycol-induced oxidative damage in two ecotypes of reed suspension cultures. J Plant Physiol (2007) 0.85
Metastatic splenic α-fetoprotein-producing adenocarcinoma: report of a case. Surg Today (2011) 0.84
Inhibition of adenovirus infections by siRNA-mediated silencing of early and late adenoviral gene functions. Antiviral Res (2010) 0.84
NGF-induced Tyro3 and Axl function as survival factors for differentiating PC12 cells. Biochem Biophys Res Commun (2008) 0.84
Parkin mutations reduce the complexity of neuronal processes in iPSC-derived human neurons. Stem Cells (2015) 0.84
Pomalidomide: evaluation of cytochrome P450 and transporter-mediated drug-drug interaction potential in vitro and in healthy subjects. J Clin Pharmacol (2014) 0.83
A bidirectional Tet-dependent promotor construct regulating the expression of E1A for tight control of oncolytic adenovirus replication. J Biotechnol (2006) 0.83
Clinical pharmacokinetics of thalidomide. Clin Pharmacokinet (2004) 0.83
Self-assembled biodegradable protein-polymer vesicle as a tumor-targeted nanocarrier. ACS Appl Mater Interfaces (2014) 0.83
Preparation of gelatin microspheres encapsulated with bFGF for therapeutic angiogenesis in a canine ischemic hind limb. J Biomater Sci Polym Ed (2010) 0.82