PubRank

Mary C Dinauer

Author PubWeight™ 88.17‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases. Cell Signal 2005 4.74
2 Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A 2009 3.87
3 A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. Blood 2009 2.35
4 The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis. J Exp Med 2006 2.03
5 Neutrophil caveolin-1 expression contributes to mechanism of lung inflammation and injury. Am J Physiol Lung Cell Mol Physiol 2007 1.97
6 Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. Blood 2007 1.92
7 Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat Immunol 2011 1.76
8 Role of NADPH oxidase in the mechanism of lung neutrophil sequestration and microvessel injury induced by Gram-negative sepsis: studies in p47phox-/- and gp91phox-/- mice. J Immunol 2002 1.60
9 Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol 2007 1.56
10 Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles. J Immunol 2004 1.55
11 Creation of a genetic system for analysis of the phagocyte respiratory burst: high-level reconstitution of the NADPH oxidase in a nonhematopoietic system. Blood 2002 1.54
12 Autophagy proteins control goblet cell function by potentiating reactive oxygen species production. EMBO J 2013 1.47
13 Rac2 concentrations in umbilical cord neutrophils. Biol Neonate 2006 1.39
14 Chemoattractant-stimulated Rac activation in wild-type and Rac2-deficient murine neutrophils: preferential activation of Rac2 and Rac2 gene dosage effect on neutrophil functions. J Immunol 2002 1.37
15 Mutational analysis reveals distinct features of the Nox4-p22 phox complex. J Biol Chem 2008 1.34
16 Gene therapy of chronic granulomatous disease: the engraftment dilemma. Mol Ther 2010 1.34
17 Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase. Proc Natl Acad Sci U S A 2011 1.30
18 Interferon-γ production by neutrophils during bacterial pneumonia in mice. Am J Respir Crit Care Med 2010 1.29
19 Fc gamma R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome. Blood 2008 1.27
20 Rac2 is critical for neutrophil primary granule exocytosis. Blood 2004 1.26
21 Absence of proton channels in COS-7 cells expressing functional NADPH oxidase components. J Gen Physiol 2002 1.23
22 Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner. J Immunol 2010 1.21
23 Deletion mutagenesis of p22phox subunit of flavocytochrome b558: identification of regions critical for gp91phox maturation and NADPH oxidase activity. J Biol Chem 2006 1.19
24 Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3. Biochem J 2007 1.17
25 Macrophage NADPH oxidase flavocytochrome B localizes to the plasma membrane and Rab11-positive recycling endosomes. J Immunol 2009 1.17
26 Critical role of myeloperoxidase and nicotinamide adenine dinucleotide phosphate-oxidase in high-burden systemic infection of mice with Candida albicans. J Infect Dis 2002 1.16
27 Rac2 regulates neutrophil chemotaxis, superoxide production, and myeloid colony formation through multiple distinct effector pathways. J Immunol 2005 1.15
28 The Rac effector p67phox regulates phagocyte NADPH oxidase by stimulating Vav1 guanine nucleotide exchange activity. Mol Cell Biol 2006 1.13
29 Rac activation induces NADPH oxidase activity in transgenic COSphox cells, and the level of superoxide production is exchange factor-dependent. J Biol Chem 2002 1.12
30 Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species. J Biol Chem 2004 1.09
31 Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans. J Clin Invest 2010 1.09
32 A critical role of protein kinase C delta activation loop phosphorylation in formyl-methionyl-leucyl-phenylalanine-induced phosphorylation of p47(phox) and rapid activation of nicotinamide adenine dinucleotide phosphate oxidase. J Immunol 2007 1.06
33 The hemopoietic Rho/Rac guanine nucleotide exchange factor Vav1 regulates N-formyl-methionyl-leucyl-phenylalanine-activated neutrophil functions. J Immunol 2003 1.05
34 Cupric yersiniabactin is a virulence-associated superoxide dismutase mimic. ACS Chem Biol 2013 1.01
35 Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain. J Biol Chem 2004 1.00
36 Reconstitution of chemotactic peptide-induced nicotinamide adenine dinucleotide phosphate (reduced) oxidase activation in transgenic COS-phox cells. J Immunol 2004 0.99
37 Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2. J Biol Chem 2011 0.98
38 Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2. Proc Natl Acad Sci U S A 2011 0.98
39 p21-activated kinase (Pak) regulates NADPH oxidase activation in human neutrophils. Blood 2005 0.97
40 Site-specific inhibitors of NADPH oxidase activity and structural probes of flavocytochrome b: characterization of six monoclonal antibodies to the p22phox subunit. J Immunol 2004 0.96
41 Regulation of the NADPH oxidase and associated ion fluxes during phagocytosis. Traffic 2013 0.95
42 Newly diagnosed chronic granulomatous disease in a 53-year-old woman with Crohn disease. Ann Allergy Asthma Immunol 2005 0.95
43 Gene therapy for chronic granulomatous disease. Expert Opin Biol Ther 2004 0.94
44 p40phox: the last NADPH oxidase subunit. Blood Cells Mol Dis 2005 0.94
45 Suppressed hindlimb perfusion in Rac2-/- and Nox2-/- mice does not result from impaired collateral growth. Am J Physiol Heart Circ Physiol 2009 0.94
46 Effects of IFN-γ on intracellular trafficking and activity of macrophage NADPH oxidase flavocytochrome b558. J Leukoc Biol 2012 0.93
47 Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice. Mol Cell Biol 2007 0.93
48 The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis. Mol Cell Biol 2011 0.93
49 Impaired NADPH oxidase activity in Rac2-deficient murine neutrophils does not result from defective translocation of p47phox and p67phox and can be rescued by exogenous arachidonic acid. J Leukoc Biol 2005 0.92
50 An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD. Blood 2013 0.92
51 Mutagenesis of p22(phox) histidine 94. A histidine in this position is not required for flavocytochrome b558 function. J Biol Chem 2002 0.91
52 Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease. J Invest Dermatol 2002 0.90
53 p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation. J Biol Chem 2010 0.90
54 Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production. J Biol Chem 2007 0.89
55 Granulocyte colony-stimulating factor prior to nonmyeloablative irradiation decreases murine host hematopoietic stem cell function and increases engraftment of donor marrow cells. Stem Cells 2007 0.89
56 Gene therapy for chronic granulomatous disease. Acta Haematol 2003 0.87
57 Donor chimerism and stem cell function in a murine congenic transplantation model after low-dose radiation conditioning: effects of a retroviral-mediated gene transfer protocol and implications for gene therapy. Exp Hematol 2002 0.87
58 A fluorescently tagged C-terminal fragment of p47phox detects NADPH oxidase dynamics during phagocytosis. Mol Biol Cell 2009 0.87
59 Antibody targeting KIT as pretransplantation conditioning in immunocompetent mice. Blood 2010 0.86
60 The role of nicotinamide adenine dinucleotide phosphate oxidase-derived reactive oxygen species in the acquisition of metastatic ability of tumor cells. Am J Pathol 2006 0.85
61 Long-term high-level reconstitution of NADPH oxidase activity in murine X-linked chronic granulomatous disease using a bicistronic vector expressing gp91phox and a Delta LNGFR cell surface marker. Hum Gene Ther 2003 0.85
62 From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease. Hum Gene Ther Clin Dev 2013 0.84
63 Phosphorylation of p22phox on threonine 147 enhances NADPH oxidase activity by promoting p47phox binding. J Biol Chem 2009 0.84
64 The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts. Am J Pathol 2008 0.82
65 Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells. J Immunol 2012 0.81
66 A murine model of antimetabolite-based, submyeloablative conditioning for bone marrow transplantation: biologic insights and potential applications. Exp Hematol 2004 0.80
67 Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. Am J Respir Cell Mol Biol 2015 0.80
68 Characterization of P-Rex1 for its role in fMet-Leu-Phe-induced superoxide production in reconstituted COS(phox) cells. Cell Signal 2010 0.80
69 Retroviral-mediated gene transfer and nonmyeloablative conditioning: studies in a murine X-linked chronic granulomatous disease model. J Pediatr Hematol Oncol 2002 0.79
70 Stable long-term gene correction with low-dose radiation conditioning in murine X-linked chronic granulomatous disease. Blood Cells Mol Dis 2004 0.78
71 In vivo role of myeloperoxidase for the host defense. Jpn J Infect Dis 2004 0.78
72 Gene correction reduces cutaneous inflammation and granuloma formation in murine X-linked chronic granulomatous disease. J Invest Dermatol 2005 0.78
73 Activation of neutrophil respiratory burst by fungal particles requires phosphatidylinositol 3-phosphate binding to p40(phox) in humans but not in mice. Blood 2012 0.77
74 The C-terminal flavin domain of gp91phox bound to plasma membranes of granulocyte-like X-CGD PLB-985 cells is sufficient to anchor cytosolic oxidase components and support NADPH oxidase-associated diaphorase activity independent of cytosolic phospholipase A2 regulation. J Leukoc Biol 2006 0.76
75 Unusual polyclonal anti-gp91 peptide antibody interactions with X-linked chronic granulomatous disease-derived human neutrophils are not from compensatory expression of Nox proteins 1, 3, or 4. Eur J Haematol 2005 0.76
76 Mitochondrial transmembrane potential is diminished in phorbol myristate acetate-stimulated peritoneal resident macrophages isolated from wild-type mice, but not in those from gp91-phox-deficient mice. Histochem Cell Biol 2004 0.76
77 Aspergillus fumigatus Copper Export Machinery and Reactive Oxygen Intermediate Defense Counter Host Copper-Mediated Oxidative Antimicrobial Offense. Cell Rep 2017 0.75
78 Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. Eur J Haematol 2005 0.75
79 [Expression and activity of polymorphisms in the 67-kDa protein of the NADPH oxidase system]. Biomedica 2004 0.75