PubRank

Shinsuke Ishigaki

Author PubWeight™ 34.32‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Regulation of insulin biosynthesis in pancreatic beta cells by an endoplasmic reticulum-resident protein kinase IRE1. Cell Metab 2006 4.11
2 Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome. Cell Metab 2012 2.39
3 Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells. J Clin Invest 2010 2.22
4 Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis. J Neurochem 2002 1.63
5 Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis. Ann Neurol 2005 1.59
6 Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1. J Biol Chem 2007 1.57
7 Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity. J Biol Chem 2002 1.19
8 Loss of TDP-43 causes age-dependent progressive motor neuron degeneration. Brain 2013 1.05
9 Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis. J Biol Chem 2002 1.03
10 Oxidative stress induced by glutathione depletion reproduces pathological modifications of TDP-43 linked to TDP-43 proteinopathies. Neurobiol Dis 2011 0.99
11 FUS/TLS assembles into stress granules and is a prosurvival factor during hyperosmolar stress. J Cell Physiol 2013 0.96
12 Dorfin localizes to Lewy bodies and ubiquitylates synphilin-1. J Biol Chem 2003 0.95
13 Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract. Nat Med 2012 0.91
14 Disruption of axonal transport in motor neuron diseases. Int J Mol Sci 2012 0.89
15 Amyotrophic lateral sclerosis: an update on recent genetic insights. J Neurol 2013 0.89
16 Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration. Nat Commun 2013 0.88
17 Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94. PLoS One 2009 0.88
18 Dorfin prevents cell death by reducing mitochondrial localizing mutant superoxide dismutase 1 in a neuronal cell model of familial amyotrophic lateral sclerosis. J Neurochem 2004 0.86
19 FUS-regulated region- and cell-type-specific transcriptome is associated with cell selectivity in ALS/FTLD. Sci Rep 2013 0.85
20 Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis. J Neuropathol Exp Neurol 2007 0.84
21 The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons. FEBS Open Bio 2013 0.83
22 Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci Res 2010 0.82
23 Dorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosis. Am J Pathol 2003 0.81
24 Gene expression profiling toward understanding of ALS pathogenesis. Ann N Y Acad Sci 2006 0.81
25 The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons. Genes Cells 2013 0.80
26 Establishment of a system for monitoring endoplasmic reticulum redox state in mammalian cells. Lab Invest 2013 0.79
27 c-Abl inhibition delays motor neuron degeneration in the G93A mouse, an animal model of amyotrophic lateral sclerosis. PLoS One 2012 0.79
28 RNP2 of RNA recognition motif 1 plays a central role in the aberrant modification of TDP-43. PLoS One 2013 0.79
29 Caspase-1 and -3 mRNAs are differentially upregulated in motor neurons and glial cells in mutant SOD1 transgenic mouse spinal cord: a study using laser microdissection and real-time RT-PCR. Neurochem Res 2003 0.77
30 Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells. J Biol Chem 2006 0.75
31 Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis. J Biol Chem 2016 0.75
32 Gene Expression Profile of Inflammatory Myopathy with Malignancy is Similar to that of Dermatomyositis rather than Polymyositis. Intern Med 2016 0.75
33 [Motor neuron disease up-to date]. No To Shinkei 2005 0.75
34 Transcriptional and post-transcriptional regulation of transmembrane protein 132A. Mol Cell Biochem 2015 0.75