Published in Cell Cycle on March 03, 2010
The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer? EMBO Rep (2010) 4.05
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response. Oncotarget (2012) 1.85
MiR-200, a new star miRNA in human cancer. Cancer Lett (2013) 1.50
The F-box protein Ppa is a common regulator of core EMT factors Twist, Snail, Slug, and Sip1. J Cell Biol (2011) 1.40
Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases. Am J Pathol (2011) 1.33
The metastatic niche and stromal progression. Cancer Metastasis Rev (2012) 1.30
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression. J Clin Invest (2012) 1.29
Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2. Cancer Res (2013) 1.27
MicroRNA-708 induces apoptosis and suppresses tumorigenicity in renal cancer cells. Cancer Res (2011) 1.21
ZEB2 mediates multiple pathways regulating cell proliferation, migration, invasion, and apoptosis in glioma. PLoS One (2012) 1.21
Molecular pathways: linking tumor microenvironment to epithelial-mesenchymal transition in metastasis. Clin Cancer Res (2014) 1.17
Inducible expression of TGFβ, snail and Zeb1 recapitulates EMT in vitro and in vivo in a NSCLC model. Clin Exp Metastasis (2011) 1.14
Mesenchymal traits are selected along with stem features in breast cancer cells grown as mammospheres. Cell Cycle (2012) 1.14
Coupled reversible and irreversible bistable switches underlying TGFβ-induced epithelial to mesenchymal transition. Biophys J (2013) 1.12
Epithelial-mesenchymal transition in ovarian carcinoma. Front Oncol (2012) 1.07
MicroRNA Control of Invasion and Metastasis Pathways. Front Genet (2011) 1.02
The miR-200 family and the miR-183~96~182 cluster target Foxf2 to inhibit invasion and metastasis in lung cancers. Oncogene (2015) 1.01
MiR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma. Oncol Rep (2014) 0.98
Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells. Breast Cancer Res (2013) 0.96
Cooperative effects of Akt-1 and Raf-1 on the induction of cellular senescence in doxorubicin or tamoxifen treated breast cancer cells. Oncotarget (2011) 0.89
MicroRNA-19 triggers epithelial-mesenchymal transition of lung cancer cells accompanied by growth inhibition. Lab Invest (2015) 0.87
Emerging role for epithelial polarity proteins of the Crumbs family as potential tumor suppressors. J Biomed Biotechnol (2011) 0.87
FOXL1, a novel candidate tumor suppressor, inhibits tumor aggressiveness and predicts outcome in human pancreatic cancer. Cancer Res (2013) 0.85
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy. Oncotarget (2015) 0.84
Heterozygous deletions at the ZEB1 locus verify haploinsufficiency as the mechanism of disease for posterior polymorphous corneal dystrophy type 3. Eur J Hum Genet (2015) 0.83
The transcription factor Zeb2 regulates signaling in mast cells. J Immunol (2012) 0.79
Lethal (2) giant larvae: an indispensable regulator of cell polarity and cancer development. Int J Biol Sci (2015) 0.77
Mesenchymal marker expression is elevated in Müller cells exposed to high glucose and in animal models of diabetic retinopathy. Oncotarget (2017) 0.75
RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC. Sci Rep (2017) 0.75
Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells. Cell Death Dis (2017) 0.75
Members of the microRNA-200 family are promising therapeutic targets in cancer. Exp Ther Med (2017) 0.75
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions. Nucleic Acids Res (2005) 3.41
A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma. Cancer Cell (2013) 2.46
Direct repression of cyclin D1 by SIP1 attenuates cell cycle progression in cells undergoing an epithelial mesenchymal transition. Mol Biol Cell (2007) 1.71
SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer. Proc Natl Acad Sci U S A (2009) 1.56
Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity. Oncogene (2004) 1.44
ZEB/miR-200 feedback loop: at the crossroads of signal transduction in cancer. Int J Cancer (2012) 1.43
p73 induces apoptosis by different mechanisms. Biochem Biophys Res Commun (2005) 1.42
Liprin beta 1, a member of the family of LAR transmembrane tyrosine phosphatase-interacting proteins, is a new target for the metastasis-associated protein S100A4 (Mts1). J Biol Chem (2001) 1.34
p53 is cleaved by caspases generating fragments localizing to mitochondria. J Biol Chem (2006) 1.30
Immediate and delayed effects of E-cadherin inhibition on gene regulation and cell motility in human epidermoid carcinoma cells. Mol Cell Biol (2005) 1.15
Genetic and epigenetic alterations of the APC gene in malignant melanoma. Oncogene (2004) 1.05
MicroRNA Control of Invasion and Metastasis Pathways. Front Genet (2011) 1.02
Calpain cleavage regulates the protein stability of p73. Biochem Biophys Res Commun (2005) 0.99
The ability of Fos family members to produce phenotypic changes in epithelioid cells is not directly linked to their transactivation potentials. Oncogene (2002) 0.98
Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21. J Biol Chem (2012) 0.98
Role of the Fos family members, c-Fos, Fra-1 and Fra-2, in the regulation of cell motility. Oncogene (2003) 0.94
Mechanism of induction of apoptosis by p73 and its relevance to neuroblastoma biology. Ann N Y Acad Sci (2004) 0.93
Cleavage of the transactivation-inhibitory domain of p63 by caspases enhances apoptosis. Proc Natl Acad Sci U S A (2007) 0.92
Novel monoclonal antibodies detect Smad-interacting protein 1 (SIP1) in the cytoplasm of human cells from multiple tumor tissue arrays. Exp Mol Pathol (2010) 0.90
Lapatinib, a dual inhibitor of ErbB-1/-2 receptors, enhances effects of combination chemotherapy in bladder cancer cells. Int J Oncol (2009) 0.90
Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB. Oncotarget (2013) 0.79
Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function. J Pathol (2014) 0.76