Published in PLoS One on February 09, 2010
Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut. Cell Host Microbe (2013) 3.05
Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice. PLoS One (2012) 1.63
Microbial ecology of the murine gut associated with the development of dextran sodium sulfate-induced colitis. Inflamm Bowel Dis (2010) 1.44
Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-γ-dependent elimination of Paneth cells. Nat Immunol (2012) 1.41
Small intestinal nematode infection of mice is associated with increased enterobacterial loads alongside the intestinal tract. PLoS One (2013) 1.23
Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling. Schizophr Res (2014) 1.10
Role of commensal gut bacteria in inflammatory bowel diseases. Gut Microbes (2012) 1.08
Insights into inflammatory bowel disease using Toxoplasma gondii as an infectious trigger. Immunol Cell Biol (2011) 1.07
Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery. ISME J (2014) 1.06
Blockade of Toll-like receptor 2 prevents spontaneous cytokine release from rheumatoid arthritis ex vivo synovial explant cultures. Arthritis Res Ther (2011) 1.03
Impact of lipoteichoic acid modification on the performance of the probiotic Lactobacillus rhamnosus GG in experimental colitis. Clin Exp Immunol (2010) 0.96
The Role of Toll-Like Receptors in Diabetes-Induced Inflammation: Implications for Vascular Complications. Curr Diab Rep (2012) 0.96
Campylobacter jejuni induces extra-intestinal immune responses via Toll-like-receptor-4 signaling in conventional IL-10 deficient mice with chronic colitis. Eur J Microbiol Immunol (Bp) (2012) 0.96
The distinct roles of MMP-2 and MMP-9 in acute DSS colitis. Eur J Microbiol Immunol (Bp) (2011) 0.93
Can microbiota transplantation abrogate murine colonization resistance against Campylobacter jejuni? Eur J Microbiol Immunol (Bp) (2013) 0.93
Paeoniflorin abrogates DSS-induced colitis via a TLR4-dependent pathway. Am J Physiol Gastrointest Liver Physiol (2013) 0.92
Comprehensive postmortem analyses of intestinal microbiota changes and bacterial translocation in human flora associated mice. PLoS One (2012) 0.91
The impact of Toll-like-receptor-9 on intestinal microbiota composition and extra-intestinal sequelae in experimental Toxoplasma gondii induced ileitis. Gut Pathog (2014) 0.90
Composition of intestinal microbiota in immune-deficient mice kept in three different housing conditions. PLoS One (2014) 0.89
Nucleotide-oligomerization-domain-2 affects commensal gut microbiota composition and intracerebral immunopathology in acute Toxoplasma gondii induced murine ileitis. PLoS One (2014) 0.88
The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice. Mucosal Immunol (2013) 0.88
Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans. PLoS One (2013) 0.87
Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice. PLoS Pathog (2013) 0.87
Selective gelatinase blockage ameliorates acute DSS colitis. Eur J Microbiol Immunol (Bp) (2011) 0.86
Lysozyme promotes the release of Toll-like receptor-2 stimulants from gram-positive but not gram-negative intestinal bacteria. Gut Microbes (2011) 0.86
Anti-gluten immune response following Toxoplasma gondii infection in mice. PLoS One (2012) 0.86
Seroreactive marker for inflammatory bowel disease and associations with antibodies to dietary proteins in bipolar disorder. Bipolar Disord (2013) 0.85
Pituitary adenylate cyclase-activating polypeptide ameliorates experimental acute ileitis and extra-intestinal sequelae. PLoS One (2014) 0.84
Helicobacter pylori induced gastric immunopathology is associated with distinct microbiota changes in the large intestines of long-term infected Mongolian gerbils. PLoS One (2014) 0.83
Maternal and congenital toxoplasmosis, currently available and novel therapies in horizon. Front Microbiol (2014) 0.83
Chemokine CXCL11 links microbial stimuli to intestinal inflammation. Clin Exp Immunol (2011) 0.83
Faecalibacterium prausnitzii A2-165 has a high capacity to induce IL-10 in human and murine dendritic cells and modulates T cell responses. Sci Rep (2016) 0.83
Innate immune sensors and gastrointestinal bacterial infections. Clin Dev Immunol (2011) 0.81
Pro-inflammatory potential of Escherichia coli strains K12 and Nissle 1917 in a murine model of acute ileitis. Eur J Microbiol Immunol (Bp) (2013) 0.81
Endotoxemia-menace, marker, or mistake? J Leukoc Biol (2016) 0.80
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeruginosa in human microbiota-associated mice. Gut Pathog (2017) 0.79
MAP kinase phosphatase-2 plays a key role in the control of infection with Toxoplasma gondii by modulating iNOS and arginase-1 activities in mice. PLoS Pathog (2013) 0.79
Expression of Toll-like receptors in the mucosa of patients with ulcerative colitis. Exp Ther Med (2015) 0.77
Colonization resistance against genetically modified Escherichia coli K12 (W3110) strains is abrogated following broad-spectrum antibiotic treatment and acute ileitis. Eur J Microbiol Immunol (Bp) (2013) 0.77
Cardiolipins Act as a Selective Barrier to Toll-Like Receptor 4 Activation in the Intestine. Appl Environ Microbiol (2016) 0.75
Intestinal, extra-intestinal and systemic sequelae of Toxoplasma gondii induced acute ileitis in mice harboring a human gut microbiota. PLoS One (2017) 0.75
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell (2004) 29.32
Toll-like receptors in the induction of the innate immune response. Nature (2000) 12.23
Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science (2006) 9.95
Mucosal flora in inflammatory bowel disease. Gastroenterology (2002) 8.42
Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol (2000) 6.68
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide. Cell (2007) 6.55
High prevalence of adherent-invasive Escherichia coli associated with ileal mucosa in Crohn's disease. Gastroenterology (2004) 5.94
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 5.78
Spatial organization and composition of the mucosal flora in patients with inflammatory bowel disease. J Clin Microbiol (2005) 5.62
Bacterial flagellin is a dominant antigen in Crohn disease. J Clin Invest (2004) 5.39
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut (2004) 5.32
Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon. Gut (2003) 5.19
Deletion of TLR5 results in spontaneous colitis in mice. J Clin Invest (2007) 4.18
Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity (2006) 3.98
Endogenous ligands of Toll-like receptors. J Leukoc Biol (2004) 3.53
Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii. J Immunol (2006) 3.24
MyD88-deficient mice develop severe intestinal inflammation in dextran sodium sulfate colitis. J Gastroenterol (2005) 3.02
Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut. J Immunol (2003) 2.96
Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep (2004) 2.64
Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation. Proc Natl Acad Sci U S A (2005) 2.08
Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4. PLoS One (2007) 2.05
Exacerbation of murine ileitis by Toll-like receptor 4 mediated sensing of lipopolysaccharide from commensal Escherichia coli. Gut (2007) 1.85
Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. Am J Physiol Gastrointest Liver Physiol (2006) 1.83
Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. Am J Pathol (2006) 1.77
A synthetic TLR4 antagonist has anti-inflammatory effects in two murine models of inflammatory bowel disease. J Immunol (2005) 1.70
Lipopolysaccharides of Bacteroides fragilis, Chlamydia trachomatis and Pseudomonas aeruginosa signal via toll-like receptor 2. J Med Microbiol (2004) 1.63
Genetically related Escherichia coli strains associated with Crohn's disease. Gut (2001) 1.61
Humoral immune response to flagellin requires T cells and activation of innate immunity. J Immunol (2006) 1.45
CpG motifs of bacterial DNA exacerbate colitis of dextran sulfate sodium-treated mice. Eur J Immunol (2002) 1.30
CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation. Gastroenterology (2005) 1.25
The role of the Lps gene in experimental ulcerative colitis in mice. APMIS (1996) 1.18
Lipopolysaccharide-induced colitis in rabbits. Res Exp Med (Berl) (1986) 1.11
Definition of structural prerequisites for lipoteichoic acid-inducible cytokine induction by synthetic derivatives. J Immunol (2003) 1.10
Evidence of immunostimulating lipoprotein existing in the natural lipoteichoic acid fraction. Infect Immun (2007) 0.95
Modulation of cytokine release from colonic explants by bacterial antigens in inflammatory bowel disease. Clin Exp Immunol (2003) 0.92
Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression. Atherosclerosis (2006) 0.90
Vascular cell responsiveness to Toll-like receptor ligands in carotid atheroma. Eur J Clin Invest (2008) 0.90
Tumor necrosis factor induction by an aqueous phenol-extracted lipopolysaccharide complex from Bacteroides species. Infect Immun (1995) 0.88
Toll-like receptors in inflammatory bowel disease-stepping into uncharted territory. World J Gastroenterol (2008) 0.86
The microbiology of butyrate formation in the human colon. FEMS Microbiol Lett (2002) 7.29
Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J (2010) 5.43
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. PLoS Pathog (2012) 3.81
Interactions and competition within the microbial community of the human colon: links between diet and health. Environ Microbiol (2007) 3.29
Gram-negative bacteria aggravate murine small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii. J Immunol (2006) 3.24
The role of the gut microbiota in nutrition and health. Nat Rev Gastroenterol Hepatol (2012) 2.60
Microbial degradation of complex carbohydrates in the gut. Gut Microbes (2012) 2.51
Two routes of metabolic cross-feeding between Bifidobacterium adolescentis and butyrate-producing anaerobes from the human gut. Appl Environ Microbiol (2006) 2.43
Preventive antibacterial therapy in acute ischemic stroke: a randomized controlled trial. PLoS One (2008) 2.39
Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17. J Exp Med (2009) 2.28
High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health. Am J Clin Nutr (2011) 2.26
Novel murine infection models provide deep insights into the "ménage à trois" of Campylobacter jejuni, microbiota and host innate immunity. PLoS One (2011) 2.20
pH and peptide supply can radically alter bacterial populations and short-chain fatty acid ratios within microbial communities from the human colon. Appl Environ Microbiol (2005) 2.19
Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers. J Clin Endocrinol Metab (2002) 2.18
Restricted distribution of the butyrate kinase pathway among butyrate-producing bacteria from the human colon. J Bacteriol (2004) 2.09
Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4. PLoS One (2007) 2.05
Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon. ISME J (2012) 2.02
Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils. Gastroenterology (2007) 1.98
MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease. Gut (2010) 1.93
Transcriptional profiling of Helicobacter pylori Fur- and iron-regulated gene expression. Microbiology (2005) 1.85
Translocation of Crohn's disease Escherichia coli across M-cells: contrasting effects of soluble plant fibres and emulsifiers. Gut (2010) 1.77
The influence of diet on the gut microbiota. Pharmacol Res (2012) 1.74
Immunology of Toxoplasma gondii. Immunol Rev (2011) 1.66
The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistance. Infect Immun (2002) 1.65
Selective colonization of insoluble substrates by human faecal bacteria. Environ Microbiol (2007) 1.63
Intestinal microbiota shifts towards elevated commensal Escherichia coli loads abrogate colonization resistance against Campylobacter jejuni in mice. PLoS One (2012) 1.63
Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity. J Exp Med (2008) 1.61
Cultured representatives of two major phylogroups of human colonic Faecalibacterium prausnitzii can utilize pectin, uronic acids, and host-derived substrates for growth. Appl Environ Microbiol (2011) 1.60
The NLRP3 inflammasome is differentially activated by pneumolysin variants and contributes to host defense in pneumococcal pneumonia. J Immunol (2011) 1.54
Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonization. Infect Immun (2002) 1.43
Campylobacter jejuni induces acute enterocolitis in gnotobiotic IL-10-/- mice via Toll-like-receptor-2 and -4 signaling. PLoS One (2012) 1.42
Iron-responsive regulation of the Helicobacter pylori iron-cofactored superoxide dismutase SodB is mediated by Fur. J Bacteriol (2005) 1.40
Molecular diversity, cultivation, and improved detection by fluorescent in situ hybridization of a dominant group of human gut bacteria related to Roseburia spp. or Eubacterium rectale. Appl Environ Microbiol (2006) 1.38
NikR mediates nickel-responsive transcriptional induction of urease expression in Helicobacter pylori. Infect Immun (2002) 1.37
Differential regulation of amidase- and formamidase-mediated ammonia production by the Helicobacter pylori fur repressor. J Biol Chem (2002) 1.33
Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice. J Immunol (2008) 1.31
Oxalobacter formigenes and its role in oxalate metabolism in the human gut. FEMS Microbiol Lett (2004) 1.31
The novel Helicobacter pylori CznABC metal efflux pump is required for cadmium, zinc, and nickel resistance, urease modulation, and gastric colonization. Infect Immun (2006) 1.31
Anti-inflammatory effects of resveratrol, curcumin and simvastatin in acute small intestinal inflammation. PLoS One (2010) 1.30
Modification of intestinal microbiota and its consequences for innate immune response in the pathogenesis of campylobacteriosis. Clin Dev Immunol (2013) 1.29
The role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake. Helicobacter (2002) 1.29
The species composition of the human intestinal microbiota differs between particle-associated and liquid phase communities. Environ Microbiol (2008) 1.28
The gut anaerobe Faecalibacterium prausnitzii uses an extracellular electron shuttle to grow at oxic-anoxic interphases. ISME J (2012) 1.24
Small intestinal nematode infection of mice is associated with increased enterobacterial loads alongside the intestinal tract. PLoS One (2013) 1.23
The Helicobacter pylori CrdRS two-component regulation system (HP1364/HP1365) is required for copper-mediated induction of the copper resistance determinant CrdA. J Bacteriol (2005) 1.20
Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces. Syst Appl Microbiol (2002) 1.17
Metabolism of linoleic acid by human gut bacteria: different routes for biosynthesis of conjugated linoleic acid. J Bacteriol (2007) 1.14
Distribution of beta-glucosidase and beta-glucuronidase activity and of beta-glucuronidase gene gus in human colonic bacteria. FEMS Microbiol Ecol (2008) 1.13
Vaccination prevents Helicobacter pylori-induced alterations of the gastric flora in mice. FEMS Immunol Med Microbiol (2006) 1.13
Major phenylpropanoid-derived metabolites in the human gut can arise from microbial fermentation of protein. Mol Nutr Food Res (2013) 1.12
Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro. FEMS Microbiol Ecol (2013) 1.11
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice. Eur J Heart Fail (2008) 1.10
Magnesium uptake by CorA is essential for viability of the gastric pathogen Helicobacter pylori. Infect Immun (2002) 1.10
Impact of pH on lactate formation and utilization by human fecal microbial communities. Appl Environ Microbiol (2007) 1.06
Lactate has the potential to promote hydrogen sulphide formation in the human colon. FEMS Microbiol Lett (2009) 1.04
TRIF is a critical survival factor in viral cardiomyopathy. J Immunol (2011) 1.03
Reduced degradation of the chemokine MCP-3 by matrix metalloproteinase-2 exacerbates myocardial inflammation in experimental viral cardiomyopathy. Circulation (2011) 1.03
Atovaquone maintenance therapy prevents reactivation of toxoplasmic encephalitis in a murine model of reactivated toxoplasmosis. Antimicrob Agents Chemother (2004) 1.01
Survey of extra-intestinal immune responses in asymptomatic long-term Campylobacter jejuni-infected mice. Eur J Microbiol Immunol (Bp) (2013) 1.01
Application of 16S rRNA gene-targetted fluorescence in situ hybridization and restriction fragment length polymorphism to study porcine microbiota along the gastrointestinal tract in response to different sources of dietary fibre. FEMS Microbiol Ecol (2006) 0.99
CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity. Blood (2006) 0.99
Some are more equal than others: the role of "keystone" species in the degradation of recalcitrant substrates. Gut Microbes (2013) 0.97
Molecular monitoring of the intestinal flora by denaturing high performance liquid chromatography. J Microbiol Methods (2006) 0.97
Alterations in microbiota and fermentation products in equine large intestine in response to dietary variation and intestinal disease. Br J Nutr (2011) 0.97
Complete genome of a new Firmicutes species belonging to the dominant human colonic microbiota ('Ruminococcus bicirculans') reveals two chromosomes and a selective capacity to utilize plant glucans. Environ Microbiol (2013) 0.95
Pathogenesis of Helicobacter pylori infection. Helicobacter (2004) 0.93
Identification by RNA profiling and mutational analysis of the novel copper resistance determinants CrdA (HP1326), CrdB (HP1327), and CzcB (HP1328) in Helicobacter pylori. J Bacteriol (2002) 0.93
Expression of Toll-like receptors in the developing brain. PLoS One (2012) 0.93
Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism. BMC Genomics (2014) 0.93
Nucleotide oligomerization domains 1 and 2: regulation of expression and function in preadipocytes. J Immunol (2008) 0.92
Comprehensive postmortem analyses of intestinal microbiota changes and bacterial translocation in human flora associated mice. PLoS One (2012) 0.91
Murine infection models for the investigation of Campylobacter jejuni--host interactions and pathogenicity. Berl Munch Tierarztl Wochenschr (2015) 0.91
Interleukin-7 links T lymphocyte and intestinal epithelial cell homeostasis. PLoS One (2012) 0.89
Modelling the emergent dynamics and major metabolites of the human colonic microbiota. Environ Microbiol (2014) 0.88
Anaerostipes hadrus comb. nov., a dominant species within the human colonic microbiota; reclassification of Eubacterium hadrum Moore et al. 1976. Anaerobe (2012) 0.87
Pro-inflammatory flagellin proteins of prevalent motile commensal bacteria are variably abundant in the intestinal microbiome of elderly humans. PLoS One (2013) 0.87
Nutritional influences on the gut microbiota and the consequences for gastrointestinal health. Biochem Soc Trans (2011) 0.87
Kinetic modelling of lactate utilization and butyrate production by key human colonic bacterial species. FEMS Microbiol Ecol (2011) 0.86
Ten years after the first Helicobacter pylori genome: comparative and functional genomics provide new insights in the variability and adaptability of a persistent pathogen. FEMS Immunol Med Microbiol (2007) 0.86
Rates of production and utilization of lactate by microbial communities from the human colon. FEMS Microbiol Ecol (2011) 0.86
Expression of cellulosome components and type IV pili within the extracellular proteome of Ruminococcus flavefaciens 007. PLoS One (2013) 0.85
Mutational analysis of the Helicobacter pylori carbonic anhydrases. FEMS Immunol Med Microbiol (2005) 0.85
Small intestinal permeability in older adults. Physiol Rep (2014) 0.84
Loss of Toll-like receptor 2 and 4 leads to differential induction of endoplasmic reticulum stress and proapoptotic responses in the intestinal epithelium under conditions of chronic inflammation. J Proteome Res (2009) 0.83