PubRank

Helmut Kettenmann

Author PubWeight™ 128.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007 11.11
2 Neuronal or glial progeny: regional differences in radial glia fate. Neuron 2003 3.68
3 Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J Neurosci 2003 2.29
4 The brain tumor microenvironment. Glia 2011 2.13
5 Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Mol Cell Neurosci 2003 1.94
6 Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis. Glia 2006 1.90
7 Neurotransmitter receptors on microglia. Trends Neurosci 2007 1.84
8 Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J Neuropathol Exp Neurol 2005 1.76
9 Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci 2007 1.74
10 Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia. Am J Physiol Cell Physiol 2003 1.69
11 The brain tumor microenvironment. Glia 2012 1.66
12 Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival. J Neurosci 2005 1.65
13 The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. J Mol Med (Berl) 2013 1.64
14 How does intracellular Ca2+ oscillate: by chance or by the clock? Biophys J 2007 1.60
15 Heterogeneity in astrocyte morphology and physiology. Brain Res Rev 2009 1.59
16 A subpopulation of precursor cells in the mouse dentate gyrus receives synaptic GABAergic input. Mol Cell Neurosci 2005 1.59
17 CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. J Neurosci 2004 1.57
18 Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology. PLoS One 2013 1.48
19 Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PLoS One 2007 1.45
20 Consensus document on European brain research. Eur J Neurosci 2011 1.45
21 Physiology of microglial cells. Brain Res Brain Res Rev 2005 1.30
22 Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function. J Neurosci 2003 1.29
23 Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro. Eur J Neurosci 2003 1.28
24 Astrocyte Ca2+ waves trigger responses in microglial cells in brain slices. FASEB J 2001 1.27
25 Different mechanisms promote astrocyte Ca2+ waves and spreading depression in the mouse neocortex. J Neurosci 2003 1.27
26 The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A. Brain 2006 1.27
27 Dopamine and noradrenaline control distinct functions in rodent microglial cells. Mol Cell Neurosci 2005 1.24
28 Synaptic transmission onto hippocampal glial cells with hGFAP promoter activity. J Cell Sci 2005 1.23
29 Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells. Brain 2010 1.23
30 Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves. Cereb Cortex 2005 1.20
31 Bergmann glial cells form distinct morphological structures to interact with cerebellar neurons. J Neurosci Res 2002 1.19
32 Astrocyte responses to neuronal activity. Glia 2004 1.19
33 Calcium signals driven by single channel noise. PLoS Comput Biol 2010 1.18
34 Purinergic signaling and microglia. Pflugers Arch 2006 1.17
35 Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice. PLoS One 2011 1.17
36 Pharmacological "cross-inhibition" of connexin hemichannels and swelling activated anion channels. Glia 2009 1.16
37 Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1. Nat Med 2012 1.15
38 Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia. J Immunol 2002 1.15
39 Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response. J Pathol 2013 1.10
40 C1q, the recognition subcomponent of the classical pathway of complement, drives microglial activation. J Neurosci Res 2009 1.10
41 Oligodendrocytes in mouse corpus callosum are coupled via gap junction channels formed by connexin47 and connexin32. Glia 2010 1.10
42 Interferon-gamma differentially modulates the release of cytokines and chemokines in lipopolysaccharide- and pneumococcal cell wall-stimulated mouse microglia and macrophages. Eur J Neurosci 2002 1.09
43 Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia. Glia 2012 1.08
44 The ectonucleotidase cd39/ENTPDase1 modulates purinergic-mediated microglial migration. Glia 2008 1.08
45 Neuroscience: the brain's garbage men. Nature 2007 1.07
46 Localization of SNARE proteins and secretory organelle proteins in astrocytes in vitro and in situ. Neurosci Res 2004 1.07
47 Toll-like receptor 2 mediates microglia/brain macrophage MT1-MMP expression and glioma expansion. Neuro Oncol 2013 1.05
48 Modulation of fate determinants Olig2 and Pax6 in resident glia evokes spiking neuroblasts in a model of mild brain ischemia. Stroke 2010 1.04
49 Functional role of calcium signals for microglial function. Glia 2006 1.02
50 Neuroprotective role of bradykinin because of the attenuation of pro-inflammatory cytokine release from activated microglia. J Neurochem 2007 1.01
51 The potassium channels Kv1.5 and Kv1.3 modulate distinct functions of microglia. Mol Cell Neurosci 2006 1.00
52 Microglia express GABA(B) receptors to modulate interleukin release. Mol Cell Neurosci 2004 0.99
53 A1 adenosine receptors in microglia control glioblastoma-host interaction. Cancer Res 2006 0.99
54 Impact of actin filament stabilization on adult hippocampal and olfactory bulb neurogenesis. J Neurosci 2010 0.99
55 Enriched environment and physical activity reduce microglia and influence the fate of NG2 cells in the amygdala of adult mice. Cell Tissue Res 2011 0.99
56 Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. J Neurochem 2005 0.98
57 Astrocytes discriminate and selectively respond to the activity of a subpopulation of neurons within the barrel cortex. Cereb Cortex 2008 0.98
58 An alpha5beta1 integrin inhibitor attenuates glioma growth. Mol Cell Neurosci 2008 0.97
59 Activation of serotonin receptors promotes microglial injury-induced motility but attenuates phagocytic activity. Brain Behav Immun 2011 0.97
60 The microglia-activating potential of thrombin: the protease is not involved in the induction of proinflammatory cytokines and chemokines. J Biol Chem 2004 0.97
61 Glioma-associated microglial MMP9 expression is upregulated by TLR2 signaling and sensitive to minocycline. Int J Cancer 2014 0.96
62 Bone marrow-derived cells expressing green fluorescent protein under the control of the glial fibrillary acidic protein promoter do not differentiate into astrocytes in vitro and in vivo. J Neurosci 2003 0.96
63 Impacting our young. Proc Natl Acad Sci U S A 2010 0.96
64 Temperature and nitric oxide control spontaneous calcium transients in astrocytes. Cell Calcium 2007 0.96
65 Requirement of functional ryanodine receptor type 3 for astrocyte migration. FASEB J 2001 0.96
66 TRPM3 is expressed in sphingosine-responsive myelinating oligodendrocytes. J Neurochem 2010 0.96
67 Acute neuroprotection by pioglitazone after mild brain ischemia without effect on long-term outcome. Exp Neurol 2008 0.95
68 The subpopulation of microglia sensitive to neurotransmitters/neurohormones is modulated by stimulation with LPS, interferon-γ, and IL-4. Glia 2014 0.94
69 Functional expression of the ecto-ATPase NTPDase2 and of nucleotide receptors by neuronal progenitor cells in the adult murine hippocampus. J Neurosci Res 2005 0.94
70 Membrane currents and cytoplasmic sodium transients generated by glutamate transport in Bergmann glial cells. Pflugers Arch 2007 0.93
71 Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH. J Biol Chem 2005 0.92
72 GABA Triggers a [Ca2+]i Increase in Murine Precursor Cells of the Oligodendrocyte Lineage. Eur J Neurosci 1992 0.91
73 Mitochondrial exchanger NCLX plays a major role in the intracellular Ca2+ signaling, gliotransmission, and proliferation of astrocytes. J Neurosci 2013 0.91
74 Store-operated Ca2+ entry in astrocytes: different spatial arrangement of endoplasmic reticulum explains functional diversity in vitro and in situ. Cell Calcium 2007 0.91
75 The principal neurons of the medial nucleus of the trapezoid body and NG2(+) glial cells receive coordinated excitatory synaptic input. J Gen Physiol 2009 0.90
76 The antitumorigenic response of neural precursors depends on subventricular proliferation and age. Stem Cells 2008 0.90
77 Astrocyte function is modified by Alzheimer's disease-like pathology in aged mice. J Alzheimers Dis 2009 0.90
78 Astrocytes from mouse brain slices express ClC-2-mediated Cl- currents regulated during development and after injury. Mol Cell Neurosci 2003 0.90
79 GDNF mediates glioblastoma-induced microglia attraction but not astrogliosis. Acta Neuropathol 2013 0.90
80 Inhibition of Rho-dependent pathways by Clostridium botulinum C3 protein induces a proinflammatory profile in microglia. Glia 2008 0.90
81 Extracellular application of nicotinic acid adenine dinucleotide phosphate induces Ca2+ signaling in astrocytes in situ. J Biol Chem 2005 0.89
82 ZnT-1 expression in astroglial cells protects against zinc toxicity and slows the accumulation of intracellular zinc. Glia 2004 0.89
83 Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans. PLoS Genet 2011 0.89
84 DMACM-caged adenosine nucleotides: ultrafast phototriggers for ATP, ADP, and AMP activated by long-wavelength irradiation. Chembiochem 2003 0.87
85 Ca2+ Channel Expression in the Oligodendrocyte Lineage. Eur J Neurosci 1992 0.87
86 A novel glycine receptor beta subunit splice variant predicts an unorthodox transmembrane topology. Assembly into heteromeric receptor complexes. J Biol Chem 2006 0.87
87 Neuron-astrocyte interactions in the medial nucleus of the trapezoid body. J Gen Physiol 2010 0.86
88 Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor. Cell Calcium 2011 0.86
89 Panglial gap junctional communication is essential for maintenance of myelin in the CNS. J Neurosci 2012 0.86
90 Nestin-expressing cells divide and adopt a complex electrophysiologic phenotype after transient brain ischemia. J Cereb Blood Flow Metab 2005 0.86
91 Generation of neuronal progenitor cells in response to tumors in the human brain. Stem Cells 2014 0.86
92 GABAergic activities enhance macrophage inflammatory protein-1alpha release from microglia (brain macrophages) in postnatal mouse brain. J Physiol 2008 0.86
93 Altered microglial phagocytosis in GPR34-deficient mice. Glia 2014 0.86
94 Brain slice invasion model reveals genes differentially regulated in glioma invasion. Biochem Biophys Res Commun 2005 0.85
95 Sodium and Calcium Currents in Glial Cells of the Mouse Corpus Callosum Slice. Eur J Neurosci 1992 0.84
96 Local origin and activity-dependent generation of nestin-expressing protoplasmic astrocytes in CA1. Brain Struct Funct 2007 0.83
97 Calcitonin gene-related peptide (CGRP) triggers Ca2+ responses in cultured astrocytes and in Bergmann glial cells from cerebellar slices. Eur J Neurosci 2008 0.82
98 Mild brain ischemia induces unique physiological properties in striatal astrocytes. Glia 2008 0.82
99 Tumor Young Investigator Award: tropism and antitumorigenic effect of endogenous neural precursors for gliomas. Clin Neurosurg 2006 0.81
100 Zinc ions are endogenous modulators of neurotransmitter-stimulated capacitative Ca2+ entry in both cultured and in situ mouse astrocytes. Eur J Neurosci 2005 0.80
101 NTPDase1 activity attenuates microglial phagocytosis. Purinergic Signal 2012 0.80
102 Single Channel Recording from Glial Cells on the Untreated Surface of the Frog Optic Nerve. Eur J Neurosci 1991 0.79
103 γ-Aminobutyric acid-ρ expression in ependymal glial cells of the mouse cerebellum. J Neurosci Res 2013 0.79
104 GABAA receptor-expressing astrocytes in the supraoptic nucleus lack glutamate uptake and receptor currents. Glia 2003 0.79
105 The tyrosine kinase inhibitor AG126 restores receptor signaling and blocks release functions in activated microglia (brain macrophages) by preventing a chronic rise in the intracellular calcium level. J Neurochem 2004 0.77
106 Membrane-type 1 metalloproteinase is upregulated in microglia/brain macrophages in neurodegenerative and neuroinflammatory diseases. J Neurosci Res 2013 0.77
107 Anti-inflammatory effects of kinins via microglia in the central nervous system. Biol Chem 2006 0.77
108 Characterization of a mouse tet-on glia precursor cell line in vitro and in vivo using the electrophysiological measurement. J Physiol Paris 2002 0.76
109 The capsaicin receptor TRPV1 as a novel modulator of neural precursor cell proliferation. Stem Cells 2014 0.76
110 Introduction. Brain Res Brain Res Rev 2005 0.76
111 Tyrosine kinase inhibition reduces inflammation in the acute stage of experimental pneumococcal meningitis. Infect Immun 2004 0.75
112 842 Glioblastoma-induced Neurogenesis. Neurosurgery 2005 0.75
113 Functional importance of inositol-1,4,5-triphosphate-induced intracellular Ca2+ mobilization in galanin-induced microglial migration. J Neurochem 2011 0.75
114 Tyrphostin AG126 exerts neuroprotection in CNS inflammation by a dual mechanism. Glia 2015 0.75
115 In memoriam: an appreciation of Richard Orkand: 1936-2002. Glia 2002 0.75
116 Retracted: The ANP-cGMP-protein kinase G pathway induces a phagocytic phenotype but decreases inflammatory gene expression in microglial cells. Glia 2008 0.75
117 Glioma Induce and Exploit Microglial Membrane Type 1 Metalloprotease Expression for Tumor Expansion: 974. Neurosurgery 2009 0.75