Published in Glia on March 01, 2012
In vivo models of primary brain tumors: pitfalls and perspectives. Neuro Oncol (2012) 1.21
KCa3.1 channels are involved in the infiltrative behavior of glioblastoma in vivo. Cell Death Dis (2013) 1.10
Bringing the heavy: carbon ion therapy in the radiobiological and clinical context. Radiat Oncol (2014) 1.03
Intratumoral heterogeneity in glioblastoma: don't forget the peritumoral brain zone. Neuro Oncol (2015) 0.95
CSF1 overexpression has pleiotropic effects on microglia in vivo. Glia (2014) 0.93
Gap junctions modulate glioma invasion by direct transfer of microRNA. Oncotarget (2015) 0.91
Recapitulation of tumor heterogeneity and molecular signatures in a 3D brain cancer model with decreased sensitivity to histone deacetylase inhibition. PLoS One (2012) 0.90
Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis. Oncotarget (2015) 0.89
Cancer stem cell-specific scavenger receptor 36 drives glioblastoma progression. Stem Cells (2014) 0.89
Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype. Nat Immunol (2016) 0.89
Glioma-derived versican promotes tumor expansion via glioma-associated microglial/macrophages Toll-like receptor 2 signaling. Neuro Oncol (2014) 0.88
Cancer Stem Cell Hierarchy in Glioblastoma Multiforme. Front Surg (2016) 0.87
Innate and adaptive immune responses in neurodegeneration and repair. Immunology (2014) 0.87
Endothelial secreted factors suppress mitogen deprivation-induced autophagy and apoptosis in glioblastoma stem-like cells. PLoS One (2014) 0.86
Identification of differentially expressed genes regulated by transcription factors in glioblastomas by bioinformatics analysis. Mol Med Rep (2014) 0.84
Proinflammatory-activated glioma cells induce a switch in microglial polarization and activation status, from a predominant M2b phenotype to a mixture of M1 and M2a/B polarized cells. ASN Neuro (2014) 0.81
Mir-21-Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact. J Neurosci (2015) 0.81
Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR. Oncotarget (2016) 0.81
Glioma revisited: from neurogenesis and cancer stem cells to the epigenetic regulation of the niche. J Oncol (2012) 0.80
Synergistic inhibition of angiogenesis and glioma cell-induced angiogenesis by the combination of temozolomide and enediyne antibiotic lidamycin. Cancer Biol Ther (2014) 0.79
Inflammation and Gliomagenesis: Bi-Directional Communication at Early and Late Stages of Tumor Progression. Curr Pathobiol Rep (2013) 0.79
Differential propagation of stroma and cancer stem cells dictates tumorigenesis and multipotency. Oncogene (2016) 0.79
Detection of primary cilia in human glioblastoma. J Neurooncol (2014) 0.79
Macrophage Ablation Reduces M2-Like Populations and Jeopardizes Tumor Growth in a MAFIA-Based Glioma Model. Neoplasia (2015) 0.79
COL3A1 and SNAP91: novel glioblastoma markers with diagnostic and prognostic value. Oncotarget (2016) 0.79
Magnetic Resonance Imaging-Based Radiomic Profiles Predict Patient Prognosis in Newly Diagnosed Glioblastoma Before Therapy. Tomography (2016) 0.79
Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia. J Transl Med (2015) 0.78
Glioblastoma: Defining Tumor Niches. Trends Cancer (2015) 0.78
Role of AHR and HIF-1α in Glioblastoma Metabolism. Trends Endocrinol Metab (2017) 0.78
Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme. Oncotarget (2016) 0.78
Brevican knockdown reduces late-stage glioma tumor aggressiveness. J Neurooncol (2014) 0.77
EGF as a New Therapeutic Target for Medulloblastoma Metastasis. Cell Mol Bioeng (2015) 0.77
Semapimod sensitizes glioblastoma tumors to ionizing radiation by targeting microglia. PLoS One (2014) 0.77
Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy. Oncogenesis (2014) 0.77
KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages. Cell Death Dis (2016) 0.77
Percentage of mesenchymal stem cells in high-grade glioma tumor samples correlates with patient survival. Neuro Oncol (2017) 0.76
Hormones and immunity in cancer: are thyroid hormones endocrine players in the microglia/glioma cross-talk? Front Cell Neurosci (2015) 0.76
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination. J Exp Med (2016) 0.76
Mechanical confinement triggers glioma linear migration dependent on formin FHOD3. Mol Biol Cell (2016) 0.76
Galunisertib inhibits glioma vasculogenic mimicry formation induced by astrocytes. Sci Rep (2016) 0.76
IQGAP1 in Podosomes/Invadosomes Is Involved in the Progression of Glioblastoma Multiforme Depending on the Tumor Status. Int J Mol Sci (2017) 0.76
Ephs and Ephrins in malignant gliomas. Growth Factors (2014) 0.76
Regulation of microglial survival and proliferation in health and diseases. Semin Immunol (2016) 0.76
Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis. Oncotarget (2016) 0.76
Extracellular Vesicles in Brain Tumor Progression. Cell Mol Neurobiol (2016) 0.76
Adult neurogenesis and glial oncogenesis: when the process fails. Biomed Res Int (2014) 0.75
Antitumor activity of combined endostatin and thymidine kinase gene therapy in C6 glioma models. Cancer Med (2016) 0.75
PPIC, EMP3 and CHI3L1 Are Novel Prognostic Markers for High Grade Glioma. Int J Mol Sci (2016) 0.75
Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14. Oncotarget (2016) 0.75
Astroblastoma: beside being a tumor entity, an occasional phenotype of astrocytic gliomas? Onco Targets Ther (2015) 0.75
Immunological Evasion in Glioblastoma. Biomed Res Int (2016) 0.75
Tumor cohesion and glioblastoma cell dispersal. Future Oncol (2013) 0.75
γ-H2AX as a marker for dose deposition in the brain of wistar rats after synchrotron microbeam radiation. PLoS One (2015) 0.75
Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice. Sci Rep (2016) 0.75
Advantages of a dual-color fluorescence-tracing glioma orthotopic implantation model: Detecting tumor location, angiogenesis, cellular fusion and the tumor microenvironment. Exp Ther Med (2015) 0.75
Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling. J Neuropathol Exp Neurol (2016) 0.75
Using the neurofibromatosis tumor predisposition syndromes to understand normal nervous system development. Scientifica (Cairo) (2014) 0.75
Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells. Cell Commun Signal (2017) 0.75
A comprehensive view of tumor stem cells and their regulation by the microenvironment in glioblastoma. Neurol Sci (2016) 0.75
Remodeling the blood-brain barrier microenvironment by natural products for brain tumor therapy. Acta Pharm Sin B (2017) 0.75
Tumour exosomes from cells harbouring PTPRZ1-MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma. Oncogene (2017) 0.75
Crosstalk between M2 macrophages and glioma stem cells. Cell Oncol (Dordr) (2017) 0.75
Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci (2007) 11.11
CSF-1R inhibition alters macrophage polarization and blocks glioma progression. Nat Med (2013) 5.04
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell (2009) 4.94
A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle. Nat Med (2012) 4.64
Differential exoprotease activities confer tumor-specific serum peptidome patterns. J Clin Invest (2006) 4.37
The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev (2009) 4.15
Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma. Nat Rev Cancer (2010) 4.10
Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes. Mol Cell (2003) 3.68
Neuronal or glial progeny: regional differences in radial glia fate. Neuron (2003) 3.68
PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev (2008) 3.50
Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science (2013) 3.45
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell (2010) 3.34
Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response. Proc Natl Acad Sci U S A (2012) 3.12
Mouse models of brain tumors and their applications in preclinical trials. Clin Cancer Res (2006) 2.68
Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies. Nat Genet (2009) 2.51
Self-renewal does not predict tumor growth potential in mouse models of high-grade glioma. Cancer Cell (2012) 2.50
Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01. Clin Cancer Res (2005) 2.46
Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt. Cancer Res (2002) 2.45
Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res (2004) 2.36
Segregated expression of AMPA-type glutamate receptors and glutamate transporters defines distinct astrocyte populations in the mouse hippocampus. J Neurosci (2003) 2.29
The brain tumor microenvironment. Glia (2011) 2.13
Serum peptide profiling by magnetic particle-assisted, automated sample processing and MALDI-TOF mass spectrometry. Anal Chem (2004) 2.07
mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma. Neoplasia (2005) 2.04
Genetically engineered models have advantages over xenografts for preclinical studies. Cancer Res (2006) 2.01
Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma. Cancer Res (2010) 1.97
Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice. Oncogene (2004) 1.96
Subpopulation of nestin-expressing progenitor cells in the adult murine hippocampus shows electrophysiological and morphological characteristics of astrocytes. Mol Cell Neurosci (2003) 1.94
Type-2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis. Glia (2006) 1.90
Modeling Adult Gliomas Using RCAS/t-va Technology. Transl Oncol (2009) 1.89
Molecular characterization of the pediatric preclinical testing panel. Clin Cancer Res (2008) 1.84
Neurotransmitter receptors on microglia. Trends Neurosci (2007) 1.84
PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas. Genes Dev (2010) 1.82
Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma. Cancer Res (2002) 1.82
Microglia stimulate the invasiveness of glioma cells by increasing the activity of metalloprotease-2. J Neuropathol Exp Neurol (2005) 1.76
Dissecting tumor maintenance requirements using bioluminescence imaging of cell proliferation in a mouse glioma model. Nat Med (2004) 1.76
Siah regulation of Pard3A controls neuronal cell adhesion during germinal zone exit. Science (2010) 1.74
Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci (2007) 1.74
Notch signaling enhances nestin expression in gliomas. Neoplasia (2006) 1.73
Radiation resistance and stem-like cells in brain tumors. Cancer Cell (2006) 1.70
Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia. Am J Physiol Cell Physiol (2003) 1.69
Molecular imaging of Akt kinase activity. Nat Med (2007) 1.68
Loss of ATM/Chk2/p53 pathway components accelerates tumor development and contributes to radiation resistance in gliomas. Cancer Cell (2010) 1.68
The role of radiotherapy following gross-total resection of atypical meningiomas. J Neurosurg (2012) 1.67
Cancer stem cells and survival pathways. Cell Cycle (2008) 1.66
Genetically engineered mouse models of brain cancer and the promise of preclinical testing. Brain Pathol (2009) 1.66
Allelic losses at 1p36 and 19q13 in gliomas: correlation with histologic classification, definition of a 150-kb minimal deleted region on 1p36, and evaluation of CAMTA1 as a candidate tumor suppressor gene. Clin Cancer Res (2005) 1.65
Glioblastoma-induced attraction of endogenous neural precursor cells is associated with improved survival. J Neurosci (2005) 1.65
The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. J Mol Med (Berl) (2013) 1.64
Insulin-like growth factor binding protein 2 promotes glioma development and progression. Proc Natl Acad Sci U S A (2007) 1.61
Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas. Cancer Res (2008) 1.60
How does intracellular Ca2+ oscillate: by chance or by the clock? Biophys J (2007) 1.60
p27 deficiency is associated with migration defects in PDGF-expressing gliomas in vivo. Cell Cycle (2010) 1.59
Heterogeneity in astrocyte morphology and physiology. Brain Res Rev (2009) 1.59
A subpopulation of precursor cells in the mouse dentate gyrus receives synaptic GABAergic input. Mol Cell Neurosci (2005) 1.59
Postgenomic global analysis of translational control induced by oncogenic signaling. Oncogene (2004) 1.58
CXCR3-dependent microglial recruitment is essential for dendrite loss after brain lesion. J Neurosci (2004) 1.57
YKL-40 and matrix metalloproteinase-9 as potential serum biomarkers for patients with high-grade gliomas. Clin Cancer Res (2006) 1.53
Platelet-derived growth factor (PDGF) and glial tumorigenesis. Cancer Lett (2005) 1.53
Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas. EMBO J (2011) 1.49
Magnetic resonance imaging determination of tumor grade and early response to temozolomide in a genetically engineered mouse model of glioma. Clin Cancer Res (2007) 1.48
Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology. PLoS One (2013) 1.48
Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis. Cancer Res (2005) 1.47
Perifosine inhibits multiple signaling pathways in glial progenitors and cooperates with temozolomide to arrest cell proliferation in gliomas in vivo. Cancer Res (2005) 1.46
Defining future directions in spinal cord tumor research: proceedings from the National Institutes of Health workshop. J Neurosurg Spine (2010) 1.45
Consensus document on European brain research. Eur J Neurosci (2011) 1.45
Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PLoS One (2007) 1.45
A prognostic gene expression signature in infratentorial ependymoma. Acta Neuropathol (2012) 1.44
miR-34a repression in proneural malignant gliomas upregulates expression of its target PDGFRA and promotes tumorigenesis. PLoS One (2012) 1.44
Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. Cancer Res (2004) 1.41
c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. Neoplasia (2003) 1.40
Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation. J Neurosci (2009) 1.38
Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression. PLoS One (2011) 1.37
Constitutive activation of Raf-1 induces glioma formation in mice. Neoplasia (2008) 1.36
Inferring transcriptional and microRNA-mediated regulatory programs in glioblastoma. Mol Syst Biol (2012) 1.36
DNA damage response and growth factor signaling pathways in gliomagenesis and therapeutic resistance. Cancer Res (2011) 1.33
A physical sciences network characterization of non-tumorigenic and metastatic cells. Sci Rep (2013) 1.33
The perivascular niche microenvironment in brain tumor progression. Cell Cycle (2010) 1.30
Physiology of microglial cells. Brain Res Brain Res Rev (2005) 1.30
Glioma formation, cancer stem cells, and akt signaling. Stem Cell Rev (2008) 1.30
Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control of release function. J Neurosci (2003) 1.29
Genetic modeling of gliomas in mice: new tools to tackle old problems. Glia (2011) 1.28
Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro. Eur J Neurosci (2003) 1.28
Astrocyte Ca2+ waves trigger responses in microglial cells in brain slices. FASEB J (2001) 1.27
Different mechanisms promote astrocyte Ca2+ waves and spreading depression in the mouse neocortex. J Neurosci (2003) 1.27
The invasion promoting effect of microglia on glioblastoma cells is inhibited by cyclosporin A. Brain (2006) 1.27
Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer. Proc Natl Acad Sci U S A (2002) 1.26
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice. J Clin Invest (2011) 1.25
The ABCG2 resistance network of glioblastoma. Cell Cycle (2009) 1.24
Dopamine and noradrenaline control distinct functions in rodent microglial cells. Mol Cell Neurosci (2005) 1.24
Synaptic transmission onto hippocampal glial cells with hGFAP promoter activity. J Cell Sci (2005) 1.23
Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells. Brain (2010) 1.23
Activity-dependent ATP-waves in the mouse neocortex are independent from astrocytic calcium waves. Cereb Cortex (2005) 1.20
Bergmann glial cells form distinct morphological structures to interact with cerebellar neurons. J Neurosci Res (2002) 1.19