PubRank

J E Groopman

Author PubWeight™ 240.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987 13.84
2 Molecular characterization of human T-cell leukemia (lymphotropic) virus type III in the acquired immune deficiency syndrome. Science 1984 10.40
3 The toxicity of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987 8.52
4 HTLV-III infection in brains of children and adults with AIDS encephalopathy. Science 1985 7.70
5 Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome. N Engl J Med 1985 6.54
6 Neutralization of the AIDS retrovirus by antibodies to a recombinant envelope glycoprotein. Science 1986 5.25
7 Blocking of HIV-1 infectivity by a soluble, secreted form of the CD4 antigen. Science 1987 4.31
8 Designing CD4 immunoadhesins for AIDS therapy. Nature 1989 4.00
9 Virus envelope protein of HTLV-III represents major target antigen for antibodies in AIDS patients. Science 1985 3.81
10 Seroepidemiological studies of human T-lymphotropic retrovirus type III in acquired immunodeficiency syndrome. Lancet 1984 3.77
11 Human T lymphotropic virus type III infection of human alveolar macrophages. Blood 1986 3.66
12 Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition. Oncologist 2000 3.62
13 HTLV-III in saliva of people with AIDS-related complex and healthy homosexual men at risk for AIDS. Science 1984 3.50
14 The acquired immunodeficiency syndrome. Ann Intern Med 1983 3.49
15 HTLV-III in cells cultured from semen of two patients with AIDS. Science 1984 3.47
16 Patient, caregiver, and oncologist perceptions of cancer-related fatigue: results of a tripart assessment survey. The Fatigue Coalition. Semin Hematol 1997 3.27
17 A new HTLV-III/LAV protein encoded by a gene found in cytopathic retroviruses. Science 1986 3.20
18 A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients. Science 1985 3.05
19 A human serum mannose-binding protein inhibits in vitro infection by the human immunodeficiency virus. J Exp Med 1989 2.95
20 The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem 1998 2.88
21 HTLV-III in symptom-free seronegative persons. Lancet 1984 2.71
22 Human immunodeficiency virus type 1 challenge of chimpanzees immunized with recombinant envelope glycoprotein gp120. Proc Natl Acad Sci U S A 1988 2.34
23 Association of human T lymphotropic virus type III antibodies with sexual and other behaviors in a cohort of homosexual men from Boston with and without generalized lymphadenopathy. Am J Med 1986 2.33
24 Effect of recombinant human granulocyte-macrophage colony-stimulating factor on myelopoiesis in the acquired immunodeficiency syndrome. N Engl J Med 1987 2.31
25 Intra-blood-brain-barrier synthesis of HTLV-III-specific IgG in patients with neurologic symptoms associated with AIDS or AIDS-related complex. N Engl J Med 1985 2.20
26 Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J Biol Chem 1995 2.17
27 Biological properties of a CD4 immunoadhesin. Nature 1990 2.05
28 Suppression of in vitro haematopoiesis following human immunodeficiency virus infection. Nature 1987 1.91
29 Recombinant human erythropoietin for patients with AIDS treated with zidovudine. N Engl J Med 1990 1.89
30 Seroepidemiology of human T-lymphotropic virus type III among homosexual men with the acquired immunodeficiency syndrome or generalized lymphadenopathy and among asymptomatic controls in Boston. Ann Intern Med 1985 1.89
31 Human T-lymphotropic virus type III in high-risk, antibody-negative homosexual men. Ann Intern Med 1986 1.88
32 Prolonged zidovudine therapy in patients with AIDS and advanced AIDS-related complex. AZT Collaborative Working Group. JAMA 1989 1.84
33 Haematologic manifestations of the human immune deficiency virus (HIV). Br J Haematol 1987 1.83
34 The safety and pharmacokinetics of recombinant soluble CD4 (rCD4) in subjects with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. A phase 1 study. Ann Intern Med 1990 1.82
35 CD4+ lymphocyte function with early human immunodeficiency virus infection. Proc Natl Acad Sci U S A 1989 1.78
36 Characterization of serum neutralization response to the human immunodeficiency virus (HIV). AIDS Res Hum Retroviruses 1987 1.65
37 Production of tumor necrosis factor alpha and interleukin 1 beta by monocytic cells infected with human immunodeficiency virus. J Clin Invest 1989 1.61
38 The histiocytic disorders: a pathophysiologic analysis. Ann Intern Med 1981 1.50
39 Serological characterization of HTLV-III infection in AIDS and related disorders. J Infect Dis 1986 1.47
40 Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells. J Biol Chem 2000 1.46
41 Immune (gamma) interferon produced by a human T-lymphoblast cell line. Nature 1981 1.45
42 Quantitation of plasma human immunodeficiency virus type 1 RNA by competitive polymerase chain reaction. J Infect Dis 1992 1.44
43 Granulocyte-macrophage colony-stimulating factor mitigates the neutropenia of combined interferon alfa and zidovudine treatment of acquired immune deficiency syndrome-associated Kaposi's sarcoma. J Clin Oncol 1991 1.41
44 HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes. Blood 2001 1.40
45 Characterization of in vitro inhibition of human immunodeficiency virus by purified recombinant CD4. J Virol 1989 1.38
46 Behavioral risk factors for HIV infection among homosexual men at a Boston community health center. Am J Public Health 1988 1.37
47 Low sensitivity of ELISA testing in early HIV infection. N Engl J Med 1986 1.37
48 In vitro modification of human immunodeficiency virus infection by granulocyte-macrophage colony-stimulating factor and gamma interferon. Proc Natl Acad Sci U S A 1986 1.35
49 Styryl sulfonyl compounds inhibit translation of cyclin D1 in mantle cell lymphoma cells. Oncogene 2009 1.35
50 Hematologic manifestations of the human immune deficiency virus (HIV). Semin Hematol 1988 1.34
51 Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood 2000 1.32
52 HTLV-III infection among health care workers. Association with needle-stick injuries. JAMA 1985 1.31
53 The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood 1998 1.30
54 Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood 2001 1.30
55 Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells. J Virol 1998 1.28
56 Human immunodeficiency virus does not induce interleukin-1, interleukin-6, or tumor necrosis factor in mononuclear cells. J Virol 1990 1.28
57 Targeting of human immunodeficiency virus-infected cells by CD8+ T lymphocytes armed with universal T-cell receptors. Blood 1994 1.26
58 Epidemic of the acquired immunodeficiency syndrome: a need for economic and social planning. Ann Intern Med 1983 1.24
59 Salivary antibodies as a means of detecting human T cell lymphotropic virus type III/lymphadenopathy-associated virus infection. J Clin Microbiol 1986 1.22
60 Pathophysiology and management of HIV-associated hematologic disorders. Blood 1989 1.20
61 CD4 immunoadhesin, but not recombinant soluble CD4, blocks syncytium formation by human immunodeficiency virus type 2-infected lymphoid cells. J Virol 1990 1.20
62 Stromal cell-derived factor-1 alpha and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis. J Immunol 1998 1.18
63 Pathogenesis of B cell lymphoma in a patient with AIDS. Blood 1986 1.18
64 Anticardiolipin antibodies associated with HTLV-III infection. Br J Haematol 1987 1.18
65 Antibodies to human T-lymphotropic virus type III (HTLV-III) in saliva of acquired immunodeficiency syndrome (AIDS) patients and in persons at risk for AIDS. Blood 1986 1.17
66 Immunogenic nature of a Pol gene product of HTLV-III/LAV. Blood 1987 1.17
67 Correlation of enzyme-linked immunosorbent assays for serum human immunodeficiency virus antigen and antibodies to recombinant viral proteins with subsequent clinical outcomes in a cohort of asymptomatic homosexual men. Am J Med 1987 1.12
68 HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases. Blood 2000 1.12
69 Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells. Blood 1992 1.11
70 Production of cytokines by peripheral blood monocytes/macrophages infected with human immunodeficiency virus type 1 (HIV-1). J Infect Dis 1990 1.11
71 Endocannabinoid-like N-arachidonoyl serine is a novel pro-angiogenic mediator. Br J Pharmacol 2010 1.10
72 Antibody seronegative human T-lymphotropic virus type III (HTLV-III)-infected patients with acquired immunodeficiency syndrome or related disorders. Blood 1985 1.07
73 Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily. J Biol Chem 1994 1.06
74 Human immunodeficiency virus infection of human bone marrow stromal fibroblasts. Blood 1990 1.05
75 RAFTK, a novel member of the focal adhesion kinase family, is phosphorylated and associates with signaling molecules upon activation of mature T lymphocytes. J Exp Med 1997 1.04
76 Recombinant alpha-2 interferon therapy for Kaposi's sarcoma associated with the acquired immunodeficiency syndrome. Ann Intern Med 1984 1.04
77 Bacterial expression of the acquired immunodeficiency syndrome retrovirus p24 gag protein and its use as a diagnostic reagent. Proc Natl Acad Sci U S A 1985 1.04
78 Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene 2007 1.03
79 Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration. J Biol Chem 2001 1.03
80 Cytokine signaling through the novel tyrosine kinase RAFTK in Kaposi's sarcoma cells. J Clin Invest 1997 1.02
81 Identification and characterization of a novel tyrosine kinase from megakaryocytes. J Biol Chem 1994 1.02
82 Lack of evidence for infection of or effect on growth of hematopoietic progenitor cells after in vivo or in vitro exposure to human immunodeficiency virus. Blood 1990 1.01
83 Alternative pathway for induction of human immunodeficiency virus gene expression: involvement of the general transcription machinery. J Virol 1991 1.00
84 Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk. J Biol Chem 2000 0.99
85 Characterization of adhesive interactions between human endothelial cells and megakaryocytes. J Clin Invest 1993 0.98
86 Inhibition of serum-enhanced HIV-1 infection of U937 monocytoid cells by recombinant soluble CD4 and anti-CD4 monoclonal antibody. AIDS Res Hum Retroviruses 1990 0.97
87 Transfusion-acquired human immunodeficiency virus infection among immunocompromised persons. Ann Intern Med 1986 0.97
88 Natural and biosynthetic insulin stimulates the growth of human erythroid progenitors in vitro. J Clin Endocrinol Metab 1982 0.96
89 Virologic studies in a case of transfusion-associated AIDS. N Engl J Med 1984 0.95
90 Association of csk-homologous kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in breast cancer cells. J Biol Chem 1997 0.94
91 Causation of AIDS revealed. Nature 1984 0.93
92 Lymphokines secreted by an established lymphocyte line modulate receptor-mediated endocytosis in macrophages derived from human monocytes. J Immunol 1983 0.93
93 Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand. Blood 1992 0.93
94 Incidence and clinical significance of neutralizing antibodies in patients receiving recombinant interferon alfa-2a by intramuscular injection. Cancer 1987 0.92
95 The ultrastructural and immunohistochemical demonstration of viral particles in lymph nodes from human immunodeficiency virus-related and non-human immunodeficiency virus-related lymphadenopathy syndromes. Hum Pathol 1988 0.92
96 Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK. Blood 1998 0.91
97 Infection of nonlymphoid cells by human immunodeficiency virus type 1 or type 2. J Virol 1990 0.91
98 The pathogenesis of myelofibrosis in myeloproliferative disorders. Ann Intern Med 1980 0.91
99 Human immunodeficiency virus infection of megakaryocytic cells. Blood 1991 0.90
100 Modulation of megakaryocytopoiesis by human basic fibroblast growth factor. Blood 1994 0.90
101 Characterization of signal transduction pathways in human bone marrow endothelial cells. Blood 1997 0.90
102 Isolation and functional analysis of human B cell populations. I. Characterization of the B1+B2+ and B1+B2- subsets. J Immunol 1985 0.90
103 Regulation of platelet activation in vitro by the c-Mpl ligand, thrombopoietin. Blood 1995 0.90
104 Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2. J Biol Chem 1999 0.90
105 CD4 receptor-dependent entry of human immunodeficiency virus type-1 env-pseudotypes into CCR5-, CCR3-, and CXCR4-expressing human alveolar macrophages is preferentially mediated by the CCR5 coreceptor. Am J Respir Cell Mol Biol 1999 0.88
106 Phase 1 study of recombinant human CD4-immunoglobulin G therapy of patients with AIDS and AIDS-related complex. Antimicrob Agents Chemother 1991 0.88
107 HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation. J Immunol 2001 0.88
108 Biology and therapy of Kaposi's sarcoma. Semin Oncol 1984 0.86
109 Differential effects of interleukin-13 on cytomegalovirus and human immunodeficiency virus infection in human alveolar macrophages. Blood 1997 0.86
110 Acquired immune deficiency syndrome. AIDS: the widening gyre. Nature 1983 0.86
111 Phase I study of 2'-3'-dideoxyinosine administered orally twice daily to patients with AIDS or AIDS-related complex and hematologic intolerance to zidovudine. Am J Med 1991 0.86
112 Kaposi's sarcoma: an oncologic looking glass. Nature 1982 0.85
113 The regulation of HIV by retinoic acid correlates with cellular expression of the retinoic acid receptors. AIDS 1994 0.85
114 Cytokine production by primary bone marrow megakaryocytes. Blood 1994 0.85
115 Suramin therapy in AIDS and related disorders. Report of the US Suramin Working Group. JAMA 1987 0.84
116 The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages. Blood 1998 0.84
117 Modulation of megakaryocytopoiesis by thrombopoietin: the c-Mpl ligand. Blood 1995 0.84
118 c-Src mediates mitogenic signals and associates with cytoskeletal proteins upon vascular endothelial growth factor stimulation in Kaposi's sarcoma cells. J Immunol 2000 0.83
119 Growth factors. Ann Intern Med 1980 0.83
120 Potent inhibition of human immunodeficiency virus type 1 in primary T cells and alveolar macrophages by a combination anti-Rev strategy delivered in an adeno-associated virus vector. J Virol 1997 0.82
121 HTLV-III/LAV infection in kidney and liver transplantation. Transplant Proc 1987 0.82
122 Bone marrow toxicity of dideoxyinosine. N Engl J Med 1989 0.82
123 Hemophilus parainfluenzae prostatitis in a homosexual man with chronic lymphadenopathy syndrome and HTLV-III infection. Am J Med 1987 0.82
124 Interferon-alpha 2a in the treatment of acquired immunodeficiency syndrome-related Kaposi's sarcoma. J Immunother (1991) 1991 0.81
125 Nucleoside therapy for HIV infection--some answers, many questions. N Engl J Med 1992 0.81
126 The regulation of megakaryocytopoiesis. Blood Rev 1995 0.80
127 Hairy cell leukemia. Disease pattern and prognosis. Cancer 1984 0.79
128 Weekly doxorubicin in the treatment of patients with AIDS-related Kaposi's sarcoma. AIDS Clinical Trials Group. J Acquir Immune Defic Syndr 1993 0.78
129 HTLV-I-specific antibody in AIDS patients and others at risk. Lancet 1984 0.78
130 Surgical approach to generalized lymphadenopathy in homosexual men. J Surg Oncol 1987 0.78
131 Cytokine gene expression and synthesis by human megakaryocytic cells. Int J Cell Cloning 1992 0.78
132 Increased suppressor T cells in probable transmitters of human immunodeficiency virus infection. Am J Public Health 1989 0.78
133 Identification of a novel human immunodeficiency virus strain cytopathic to megakaryocytic cells. Blood 1993 0.78
134 Human kit ligand (stem cell factor) modulates platelet activation in vitro. J Biol Chem 1994 0.78
135 Long-term follow-up of didanosine administered orally twice daily to patients with advanced human immunodeficiency virus infection and hematologic intolerance of zidovudine. Clin Infect Dis 1993 0.78
136 Tumor infiltrates in acquired immunodeficiency syndrome patients with Kaposi's sarcoma. Lancet 1983 0.77
137 Effects of transforming growth factor beta on megakaryocytic cell fusion and endomitosis. Int J Cell Cloning 1992 0.77
138 Expression and utilization of co-receptors in HIV and simian immunodeficiency virus infection of megakaryocytes. AIDS 1999 0.77
139 Evaluation of novel cell cycle inhibitors in mantle cell lymphoma. Oncogene 2007 0.76
140 Effect of intravenous recombinant gamma-interferon on the respiratory burst of blood monocytes from patients with AIDS. J Infect Dis 1986 0.76
141 Recombinant human granulocyte-macrophage colony-stimulating factor ameliorates zidovudine-induced neutropenia in patients with acquired immunodeficiency syndrome (AIDS)/AIDS-related complex. Blood 1991 0.76
142 Signal transduction in human hematopoietic cells by vascular endothelial growth factor related protein, a novel ligand for the FLT4 receptor. Blood 1997 0.75
143 Stimulation of human immunodeficiency virus type 1 expression by ceramide. AIDS Res Hum Retroviruses 1994 0.75
144 Hepatitis from isoniazid and rifampin. N Engl J Med 1978 0.75
145 Production of gamma (immune) interferon by a permanent human T-lymphocyte cell line. Adv Exp Med Biol 1984 0.75
146 In vitro effects of stem-cell factor or interleukin-3 on myelosuppression associated with AIDS. AIDS 1994 0.75
147 Human T-lymphotropic virus type III infection in previously immunocompromised hosts. J Clin Oncol 1986 0.75
148 Isolation of human immunodeficiency virus and serum neutralising antibody. Lancet 1986 0.75
149 Retroviral vaccines. How close is C to D? Nature 1986 0.75
150 Pulmonary hypertrophic osteoarthropathy as the initial manifestation of interstitial fibrosis. N Y State J Med 1989 0.75
151 IgA deficiency and salivary transmission of human immunodeficiency virus. Lancet 1986 0.75
152 Beta-chemokine induction of activation protein-1 and cyclic AMP responsive element activation in human myeloid cells. Cell Growth Differ 2001 0.75
153 AIDS. Of mice, monkeys and men. Nature 1991 0.75
154 Acquired immunodeficiency syndrome. Introduction. Semin Oncol 1984 0.75
155 Purified recombinant CD4 inhibits HIV-1 infection of peripheral blood macrophages. Pathol Biol (Paris) 1991 0.75
156 The AIDS epidemic: continental drift. Nature 1984 0.75
157 Clinical symptomatology of the acquired immunodeficiency syndrome (AIDS) and related disorders. Prog Allergy 1986 0.75
158 Therapeutic options in hairy-cell leukemia. Semin Oncol 1985 0.75
159 Apparent transmission of human T-cell leukemia virus type III to a heterosexual woman with the acquired immunodeficiency syndrome. Ann Intern Med 1985 0.75
160 Scratching the surface. Curr Biol 1991 0.75
161 Clinical spectrum of HTLV-III in humans. Cancer Res 1985 0.75
162 GM-CSF as an alternative to dose modification of the combination zidovudine and interferon-alpha in the treatment of AIDS-associated Kaposi's sarcoma. Am J Clin Oncol 1991 0.75
163 Viruses and human neoplasia. Approaching etiology. Am J Med 1983 0.75
164 Effect of recombinant soluble CD4 on the in vitro growth of hematopoietic progenitor cells from AIDS patients. Blood 1990 0.75
165 Laying the groundwork for neutralizing AIDS-linked virus. Nature 1985 0.75
166 Transfusion in HIV disease. Curr Opin Hematol 1997 0.75
167 Therapy of epidemic Kaposi's sarcoma. Semin Hematol 1986 0.75
168 Neoplasms in the acquired immune deficiency syndrome: the multidisciplinary approach to treatment. Semin Oncol 1987 0.75
169 Transfusion associated AIDS. Transfus Med Rev 1988 0.75