Published in J Med Chem on March 25, 2010
Glycotherapy: new advances inspire a reemergence of glycans in medicine. Chem Biol (2013) 1.04
A fluorous phosphate protecting group with applications to carbohydrate synthesis. Org Lett (2011) 0.84
Corrosion inhibition of mild steel in 1M HCl by D-glucose derivatives of dihydropyrido [2,3-d:6,5-d'] dipyrimidine-2, 4, 6, 8(1H,3H, 5H,7H)-tetraone. Sci Rep (2017) 0.81
Binding mode analyses and pharmacophore model development for stilbene derivatives as a novel and competitive class of α-glucosidase inhibitors. PLoS One (2014) 0.78
Synthesis of alpha-tetrasubstituted triazoles by copper-catalyzed silyl deprotection/azide cycloaddition. Beilstein J Org Chem (2015) 0.75
Hypoglycaemic activity of ethanolic extract of Garcinia mangostana Linn. in normoglycaemic and streptozotocin-induced diabetic rats. BMC Complement Altern Med (2016) 0.75
Synthesis and biological evaluation of novel ursolic acid analogues as potential α-glucosidase inhibitors. Sci Rep (2017) 0.75
α-Glucosidase Inhibitory Activity of Selected Malaysian Plants. J Pharm Bioallied Sci (2017) 0.75
7-Chloro-4-[(E)-2-(2-methoxy-benzyl-idene)hydrazin-1-yl]quinoline monohydrate. Acta Crystallogr Sect E Struct Rep Online (2010) 1.98
Novel 1,2,3-triazole derivatives for use against Mycobacterium tuberculosis H37Rv (ATCC 27294) strain. J Med Chem (2011) 1.57
Synthesis and antitubercular activity of 7-chloro-4-quinolinylhydrazones derivatives. Bioorg Med Chem Lett (2009) 1.39
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives. Bioorg Med Chem (2009) 1.38
Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents. Eur J Med Chem (2007) 1.38
Synthesis and antitubercular activity of new mefloquine-oxazolidine derivatives. Eur J Med Chem (2010) 1.16
Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1,2,3-triazole derivatives. Bioorg Med Chem (2006) 1.13
Synthesis and anti-HSV-1 activity of new 1,2,3-triazole derivatives. Bioorg Med Chem (2011) 1.03
The antileishmanial activity assessment of unusual flavonoids from Kalanchoe pinnata. Phytochemistry (2006) 1.01
C-glycosylflavones from the aerial parts of Eleusine indica inhibit LPS-induced mouse lung inflammation. Planta Med (2005) 0.98
A chitin-like component in Aedes aegypti eggshells, eggs and ovaries. Insect Biochem Mol Biol (2007) 0.98
Vitamin C and vitamin E in prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in choline deficient diet fed rats. Nutr J (2003) 0.98
Identification of a potential lead structure for designing new antimicrobials to treat infections caused by Staphylococcus epidermidis-resistant strains. Curr Microbiol (2008) 0.97
Quercitrin: an antileishmanial flavonoid glycoside from Kalanchoe pinnata. Planta Med (2006) 0.95
Synthesis and antitubercular activity of novel Schiff bases derived from d-mannitol. Carbohydr Res (2009) 0.94
Antiviral evaluation of N-amino-1,2,3-triazoles against Cantagalo virus replication in cell culture. Eur J Med Chem (2009) 0.91
Antiplatelet properties of novel N-substituted-phenyl-1,2,3-triazole-4-acylhydrazone derivatives. Bioorg Med Chem (2003) 0.91
Molecular characterization of an acidic phospholipase A(2) from Bothrops pirajai snake venom: synthetic C-terminal peptide identifies its antiplatelet region. Arch Toxicol (2011) 0.90
2-{1-[2,8-Bis(trifluoro-meth-yl)quinolin-4-yl]-3,5,6,7,8,8a-hexa-hydro-1H-1,3-oxazolo[3,4-a]pyridin-3-yl}phenol. Acta Crystallogr Sect E Struct Rep Online (2011) 0.90
Synthesis and anti-HSV-1 activity of quinolonic acyclovir analogues. Bioorg Med Chem Lett (2006) 0.90
Enzymatic and structural characterization of a basic phospholipase A(2) from the sea anemone Condylactis gigantea. Biochimie (2010) 0.89
Synthesis, antiplatelet and in silico evaluations of novel N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides. Bioorg Med Chem (2009) 0.87
Biological evaluation of hydroxynaphthoquinones as anti-malarials. Malar J (2013) 0.87
Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones. Bioorg Med Chem (2008) 0.87
Mefloquine-oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113. Bioorg Med Chem (2011) 0.86
The role of platelet and plasma markers of antioxidant status and oxidative stress in thrombocytopenia among patients with vivax malaria. Mem Inst Oswaldo Cruz (2008) 0.85
Synthesis, antitubercular activity, and SAR study of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides. Bioorg Med Chem (2011) 0.84
Lipid peroxidation and antioxidant enzymes activity in Plasmodium vivax malaria patients evolving with cholestatic jaundice. Malar J (2013) 0.84
Synthesis and potent antitumor activity of new arylamino derivatives of nor-beta-lapachone and nor-alpha-lapachone. Bioorg Med Chem (2007) 0.84
Isolation and expression of a hypotensive and anti-platelet acidic phospholipase A2 from Bothrops moojeni snake venom. J Pharm Biomed Anal (2012) 0.84
Addition of thiols to o-quinone methide: new 2-hydroxy-3-phenylsulfanylmethyl[1,4]naphthoquinones and their activity against the human malaria parasite Plasmodium falciparum (3D7). Eur J Med Chem (2012) 0.83
The compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase. Curr HIV Res (2008) 0.83
Inhibition of HSV-1 replication and HSV DNA polymerase by the chloroxoquinolinic ribonucleoside 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid and its aglycone. Antiviral Res (2007) 0.83
Quantitative structure-activity relationship in aziridinyl-1,4-naphthoquinone antimalarials: study of theoretical correlations by the PM3 method. Bioorg Med Chem (2004) 0.83
Synthesis using microwave irradiation and antibacterial evaluation of new N,O-acetals and N,S-acetals derived from 2-amino-1,4-naphthoquinones. Eur J Med Chem (2013) 0.82
Identification of nor-β-lapachone derivatives as potential antibacterial compounds against Enterococcus faecalis clinical strain. Curr Microbiol (2010) 0.81
Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives. Bioorg Med Chem (2009) 0.81
New oxirane derivatives of 1,4-naphthoquinones and their evaluation against T. cruzi epimastigote forms. Bioorg Med Chem (2012) 0.81
New hemiketal steroid from the introduced soft coral Chromonephthea braziliensis is a chemical defense against predatory fishes. J Chem Ecol (2008) 0.81
ProtozoaDB: dynamic visualization and exploration of protozoan genomes. Nucleic Acids Res (2007) 0.80
Malondialdehyde and sulfhydryl groups as biomarkers of oxidative stress in patients with systemic lupus erythematosus. Rev Bras Reumatol (2012) 0.80
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition. Eur J Med Chem (2013) 0.80
7-Chloro-4-quinolinyl hydrazones: a promising and potent class of antileishmanial compounds. Chem Biol Drug Des (2013) 0.80
Antinociceptive and anti-inflammatory kaempferol glycosides from Sedum dendroideum. J Ethnopharmacol (2009) 0.80
Nitroxides attenuate carrageenan-induced inflammation in rat paws by reducing neutrophil infiltration and the resulting myeloperoxidase-mediated damage. Free Radic Biol Med (2012) 0.80
Synthesis and antimycobacterial activity of N'-[(E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives. Eur J Med Chem (2009) 0.79
Synthesis and antitubercular activity of heteroaromatic isonicotinoyl and 7-chloro-4-quinolinyl hydrazone derivatives. ScientificWorldJournal (2010) 0.79
Synthesis, HIV-RT inhibitory activity and SAR of 1-benzyl-1H-1,2,3-triazole derivatives of carbohydrates. Eur J Med Chem (2008) 0.79
Anti-tuberculosis evaluation and conformational study of N-acylhydrazones containing the thiophene nucleus. Arch Pharm (Weinheim) (2014) 0.79
Synthesis of new 9-hydroxy-α- and 7-hydroxy-β-pyran naphthoquinones and cytotoxicity against cancer cell lines. Org Biomol Chem (2011) 0.79
Synthesis, biological, and theoretical evaluations of new 1,2,3-triazoles against the hemolytic profile of the Lachesis muta snake venom. Bioorg Med Chem (2009) 0.79
Molecular design, synthesis and biological evaluation of 1,4-dihydro-4-oxoquinoline ribonucleosides as TcGAPDH inhibitors with trypanocidal activity. Bioorg Med Chem Lett (2013) 0.79
Naphthoquinoidal [1,2,3]-triazole, a new structural moiety active against Trypanosoma cruzi. Eur J Med Chem (2007) 0.79
Syntheses and antimycobacterial activities of [(2S,3R)-2-(amino)-4-(arenesulfonamido)-3-hydroxy-1-phenylbutane derivatives. Med Chem (2014) 0.78
Structural characterization and low-resolution model of BJ-48, a thrombin-like enzyme from Bothrops jararacussu venom. Biophys Chem (2007) 0.78
Flowers from Kalanchoe pinnata are a rich source of T cell-suppressive flavonoids. Nat Prod Commun (2012) 0.78
Antitubercular activity of new coumarins. Chem Biol Drug Des (2011) 0.78
Effects of diet supplementation with Camu-camu (Myrciaria dubia HBK McVaugh) fruit in a rat model of diet-induced obesity. An Acad Bras Cienc (2013) 0.78
Oxyrane derivative of alpha-lapachone is potent growth inhibitor of Trypanosoma cruzi epimastigote forms. Parasitol Res (2006) 0.78
3-arylamino and 3-alkoxy-nor-beta-lapachone derivatives: synthesis and cytotoxicity against cancer cell lines. J Med Chem (2010) 0.78
Synthesis of alpha- and beta-pyran naphthoquinones as a new class of antitubercular agents. Arch Pharm (Weinheim) (2010) 0.78
Sequence analysis of NAT2 gene in Brazilians: identification of undescribed single nucleotide polymorphisms and molecular modeling of the N-acetyltransferase 2 protein structure. Mutat Res (2010) 0.77
Singlet oxygen production by pyrano and furano 1,4-naphthoquinones in non-aqueous medium. Photochem Photobiol Sci (2012) 0.77
Phytochemical and pharmacological study of Sedum dendroideum leaf juice. J Ethnopharmacol (2005) 0.77
In vitro and in vivo anti-malarial activity of limonoids isolated from the residual seed biomass from Carapa guianensis (andiroba) oil production. Malar J (2014) 0.76
Synthesis of new chlorin e6 trimethyl and protoporphyrin IX dimethyl ester derivatives and their photophysical and electrochemical characterizations. Chemistry (2014) 0.76
Synthesis of 1H-1,2,3-triazoles and study of their antifungal and cytotoxicity activities. Med Chem (2013) 0.76
Characterization of HIV-1 enzyme reverse transcriptase inhibition by the compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid through kinetic and in silico studies. Curr HIV Res (2009) 0.76
Trypanosoma cruzi: insights into naphthoquinone effects on growth and proteinase activity. Exp Parasitol (2010) 0.76
Effects of Passiflora nitida Kunth leaf extract on digestive enzymes and high caloric diet in rats. J Nat Med (2014) 0.76
Structure-activity relationships of novel inhibitors of glyceraldehyde-3-phosphate dehydrogenase. Bioorg Med Chem Lett (2004) 0.76
One-pot preparation of substituted pyrroles from alpha-diazocarbonyl compounds. Beilstein J Org Chem (2008) 0.75
Antivenom effects of 1,2,3-triazoles against Bothrops jararaca and Lachesis muta snakes. Biomed Res Int (2013) 0.75
Correction: Aureonitol, a Fungi-Derived Tetrahydrofuran, Inhibits Influenza Replication by Targeting Its Surface Glycoprotein Hemagglutinin. PLoS One (2015) 0.75
Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety. Bioorg Med Chem (2013) 0.75
4-[(E)-2-(2-Chloro-benzyl-idene)hydrazin-1-yl]quinolin-1-ium chloride dihydrate. Acta Crystallogr Sect E Struct Rep Online (2012) 0.75
Complete and unambiguous assignments of 1H and 13C chemical shifts of new arylamino derivatives of ortho-naphthofuranquinones. Magn Reson Chem (2008) 0.75
Synthesis and antiviral activities of new pyrazolo[4,3-c]quinolin-3-ones and their ribonucleoside derivatives. Nucleosides Nucleotides Nucleic Acids (2004) 0.75
Recent advances in the synthesis of new antimycobacterial agents based on the 1H-1,2,3-triazoles. Curr Top Med Chem (2013) 0.75
Synthesis and evaluation of D-gluconamides as green mineral scales. Carbohydr Res (2012) 0.75
Oxoquinoline derivatives: identification and structure-activity relationship (SAR) analysis of new anti-HSV-1 agents. Curr Microbiol (2011) 0.75
Synthesis, Anticlotting and Antiplatelet Effects of 1,2,3-Triazoles Derivatives. Med Chem (2016) 0.75
pi-Stacked dimers in 6-methoxy-3,3-dimethyl-3H-benzo[f]chromene, and centrosymmetric dimers containing C-H...pi(arene) hydrogen bonds in racemic 3-bromo-2,2,6,6-tetramethyl-3,4-dihydro-2H,6H-1,5-dioxatriphenylene. Acta Crystallogr C (2007) 0.75
Synthesis and antiviral evaluation of isatin ribonucleosides. Nucleosides Nucleotides Nucleic Acids (2003) 0.75
Anisotropic and hydrogen bonding effects in phenylglyoxamides and mandelamides: theoretical and NMR conformational evaluation. Magn Reson Chem (2008) 0.75
Inner reorganization during the radical-biradical transition in a nor-beta-lapachone derivative possessing two redox centers. Org Biomol Chem (2008) 0.75
New families of hetero-tri-spin 2p-3d-4f complexes: synthesis, crystal structures, and magnetic properties. Inorg Chem (2014) 0.75
Synthesis of 1,2,3-triazole glycoconjugates as inhibitors of α-glucosidases. Carbohydr Res (2012) 0.75
Three ethyl 5-amino-1-aryl-1H-imidazole-4-carboxylates: hydrogen-bonded supramolecular structures in one, two and three dimensions. Acta Crystallogr C (2006) 0.75
Optimization of sample preparation from skin mucus of a neotropical fish for two-dimensional substrate gel electrophoresis. Anal Biochem (2006) 0.75
Transfer of lipids to high-density lipoprotein (HDL) is altered in patients with familial hypercholesterolemia. Metabolism (2013) 0.75
Tuberculosis: finding a new potential antimycobacterium derivative in a aldehyde-arylhydrazone-oxoquinoline series. Curr Microbiol (2012) 0.75
First isolation of a symmetrical glycosylated methylene bisflavonoid. Planta Med (2003) 0.75