PubRank

Young S Hahn

Author PubWeight™ 36.91‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-induced mouse model through tumor necrosis factor-α production. J Biol Chem 2012 1.75
2 Myeloid suppressor cells induced by hepatitis C virus suppress T-cell responses through the production of reactive oxygen species. Hepatology 2012 1.36
3 Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt. J Virol 2004 1.34
4 The role of macrophage polarization in infectious and inflammatory diseases. Mol Cells 2014 1.28
5 Blockade of PD-1/B7-H1 interaction restores effector CD8+ T cell responses in a hepatitis C virus core murine model. J Immunol 2008 1.27
6 Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation. J Biol Chem 2004 1.25
7 Intrahepatic IL-10 maintains NKG2A+Ly49- liver NK cells in a functionally hyporesponsive state. J Immunol 2010 1.22
8 Extracellular hepatitis C virus core protein activates STAT3 in human monocytes/macrophages/dendritic cells via an IL-6 autocrine pathway. J Biol Chem 2011 1.22
9 HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production. J Leukoc Biol 2007 1.17
10 Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. J Virol 2005 1.16
11 gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway. J Immunol 2005 1.15
12 Chronically inflamed livers up-regulate expression of inhibitory B7 family members. Hepatology 2009 1.15
13 Host and viral factors in the immunopathogenesis of primary hepatitis C virus infection. Immunol Cell Biol 2006 1.14
14 HCV core/gC1qR interaction arrests T cell cycle progression through stabilization of the cell cycle inhibitor p27Kip1. Virology 2003 1.10
15 Myeloid-derived suppressor cells: the dark knight or the joker in viral infections? Immunol Rev 2013 1.05
16 Group 2 innate lymphoid cell production of IL-5 is regulated by NKT cells during influenza virus infection. PLoS Pathog 2013 1.05
17 Hepatitis C virus core protein leads to immune suppression and liver damage in a transgenic murine model. J Virol 2002 1.05
18 HCV+ hepatocytes induce human regulatory CD4+ T cells through the production of TGF-beta. PLoS One 2010 1.01
19 Role of complement in immune regulation and its exploitation by virus. Viral Immunol 2007 0.95
20 Hepatitis C virus promotes T-helper (Th)17 responses through thymic stromal lymphopoietin production by infected hepatocytes. Hepatology 2013 0.95
21 Retracted SOCS1 and SOCS3 are targeted by hepatitis C virus core/gC1qR ligation to inhibit T-cell function. J Virol 2005 0.94
22 Regulation of NK cell repertoire and function in the liver. Crit Rev Immunol 2011 0.93
23 Increased Fas ligand expression of CD4+ T cells by HCV core induces T cell-dependent hepatic inflammation. J Leukoc Biol 2005 0.89
24 Fas ligand is responsible for CXCR3 chemokine induction in CD4+ T cell-dependent liver damage. J Immunol 2006 0.88
25 Transcriptional regulation of IFN-λ genes in hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex. J Biol Chem 2014 0.88
26 The molecular basis of HCV-mediated immune dysregulation. Clin Immunol 2004 0.86
27 The C-terminal region of hepatitis C core protein is required for Fas-ligand independent apoptosis in Jurkat cells by facilitating Fas oligomerization. Virology 2003 0.86
28 Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice. Hepatology 2014 0.86
29 Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system. PLoS One 2009 0.86
30 Frequency of gC1qR+CD4+ T cells increases during acute hepatitis C virus infection and remains elevated in patients with chronic infection. Clin Immunol 2009 0.83
31 Lipidoid Nanoparticles Containing PD-L1 siRNA Delivered In Vivo Enter Kupffer Cells and Enhance NK and CD8(+) T Cell-mediated Hepatic Antiviral Immunity. Mol Ther Nucleic Acids 2013 0.82
32 Retracted gC1qR expression in chimpanzees with resolved and chronic infection: potential role of HCV core/gC1qR-mediated T cell suppression in the outcome of HCV infection. Virology 2005 0.79
33 Immunity to viruses. Immunol Rev 2013 0.78
34 Site-specific fatty acid-conjugation to prolong protein half-life in vivo. J Control Release 2013 0.77
35 The strange and critical intersection of hepatitis C and lipoprotein metabolism: "C-zing" the oil. Hepatology 2012 0.77
36 Functional characterization of core genes from patients with acute hepatitis C virus infection. J Infect Dis 2010 0.76
37 SOCS1 and SOCS3 are targeted by hepatitis C virus core/gC1qR ligation to inhibit T-cell function. J Virol 2006 0.75