Published in Mol Gen Genet on March 01, 1991
An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell death. Proc Natl Acad Sci U S A (1996) 5.25
Toxin-antitoxin modules may regulate synthesis of macromolecules during nutritional stress. J Bacteriol (2000) 3.05
Corepression of the P1 addiction operon by Phd and Doc. J Bacteriol (1998) 1.62
The solution structure of ParD, the antidote of the ParDE toxin antitoxin module, provides the structural basis for DNA and toxin binding. Protein Sci (2007) 1.14
Modular organization of the Phd repressor/antitoxin protein. J Bacteriol (2004) 1.09
The anti-toxin ParD of plasmid RK2 consists of two structurally distinct moieties and belongs to the ribbon-helix-helix family of DNA-binding proteins. Biochem J (2002) 1.06
A common origin for the bacterial toxin-antitoxin systems parD and ccd, suggested by analyses of toxin/target and toxin/antitoxin interactions. PLoS One (2012) 0.80
Replication and control of circular bacterial plasmids. Microbiol Mol Biol Rev (1998) 4.89
Pure brain-derived acidic fibroblast growth factor is a potent angiogenic vascular endothelial cell mitogen with sequence homology to interleukin 1. Proc Natl Acad Sci U S A (1985) 2.50
Identification of components of a new stability system of plasmid R1, ParD, that is close to the origin of replication of this plasmid. Mol Gen Genet (1987) 1.88
A novel solenoid fold in the cell wall anchoring domain of the pneumococcal virulence factor LytA. Nat Struct Biol (2001) 1.82
Sequence analysis of heparan sulfate epitopes with graded affinities for fibroblast growth factors 1 and 2. J Biol Chem (2001) 1.68
Comparison of ccd of F, parDE of RP4, and parD of R1 using a novel conditional replication control system of plasmid R1. Mol Microbiol (1995) 1.53
Regulation of the enzymes of the beta-ketoadipate pathway in Moraxella. Control of quinate oxidation by protocatechuate. Eur J Biochem (1970) 1.44
Purification and amino acid composition of peptide antibiotic AS-48 produced by Streptococcus (Enterococcus) faecalis subsp. liquefaciens S-48. Antimicrob Agents Chemother (1989) 1.32
Hypotensive activity of fibroblast growth factor. Science (1991) 1.32
Killing of Escherichia coli cells modulated by components of the stability system ParD of plasmid R1. Mol Gen Genet (1988) 1.31
Kid, a small protein of the parD stability system of plasmid R1, is an inhibitor of DNA replication acting at the initiation of DNA synthesis. J Mol Biol (1995) 1.26
The kis and kid genes of the parD maintenance system of plasmid R1 form an operon that is autoregulated at the level of transcription by the co-ordinated action of the Kis and Kid proteins. Mol Microbiol (1991) 1.25
Translational coupling and limited degradation of a polycistronic messenger modulate differential gene expression in the parD stability system of plasmid R1. Mol Gen Genet (1995) 1.17
Protein domains and conformational changes in the activation of RepA, a DNA replication initiator. EMBO J (1998) 1.17
Dihydroxy-2,5 benzenesulphonate (dobesilate) elicits growth arrest and apoptosis in glioma cells. Neurol Res (2005) 1.03
Broad-host-range plasmid replication: an open question. Mol Microbiol (1996) 1.03
Host growth temperature and a conservative amino acid substitution in the replication protein of pPS10 influence plasmid host range. J Bacteriol (1995) 1.00
Supra-operonic clustering of genes specifying glucose dissimilation in Pseudomonas putida. Mol Gen Genet (1976) 1.00
Control of replication of plasmid R1: the intergenic region between copA and repA modulates the level of expression of repA. Mol Microbiol (1991) 0.99
Transcription of repA, the gene of the initiation protein of the Pseudomonas plasmid pPS10, is autoregulated by interactions of the RepA protein at a symmetrical operator. J Mol Biol (1995) 0.99
Fibroblast growth factor-1 prevents myocardial apoptosis triggered by ischemia reperfusion injury. Eur J Med Res (1997) 0.96
The activation of fibroblast growth factors by heparin: synthesis, structure, and biological activity of heparin-like oligosaccharides. Chembiochem (2001) 0.96
Inhibition of yeast pyruvate carboxylase by L-aspartate and oxaloacetate. Biochem Biophys Res Commun (1966) 0.96
Common binding sites for beta-amyloid fibrils and fibroblast growth factor-2 in heparan sulfate from human cerebral cortex. J Biol Chem (1999) 0.95
Three-dimensional solution structure and stability of phage 434 Cro protein. Biochemistry (1997) 0.92
Correction of hypertension by normalization of endothelial levels of fibroblast growth factor and nitric oxide synthase in spontaneously hypertensive rats. Proc Natl Acad Sci U S A (1996) 0.90
Protection of rat myocardium by mitogenic and non-mitogenic fibroblast growth factor during post-ischemic reperfusion. Growth Factors (1997) 0.90
Cardioprotection from ischemia by fibroblast growth factor: role of inducible nitric oxide synthase. Eur J Med Res (1999) 0.87
A partly folded state of acidic fibroblast growth factor at low pH. Eur J Biochem (1997) 0.87
Solution structure of acidic fibroblast growth factor bound to 1,3, 6-naphthalenetrisulfonate: a minimal model for the anti-tumoral action of suramins and suradistas. J Mol Biol (1998) 0.87
A mutation that decreases the efficiency of plasmid R1 replication leads to the activation of parD, a killer stability system of the plasmid. FEMS Microbiol Lett (1995) 0.87
Fibroblast growth factor cardioprotection against ischemia-reperfusion injury may involve K+ ATP channels. Eur J Med Res (2000) 0.86
DnaA dependent replication of plasmid R1 occurs in the presence of point mutations that disrupt the dnaA box of oriR. Nucleic Acids Res (1992) 0.86
Dobesilate inhibits the activation of signal transducer and activator of transcription 3, and the expression of cyclin D1 and bcl-XL in glioma cells. Neurol Res (2006) 0.85
Treatment of dry age-related macular degeneration with dobesilate. BMJ Case Rep (2012) 0.85
The heat-shock DnaK protein is required for plasmid R1 replication and it is dispensable for plasmid ColE1 replication. Nucleic Acids Res (1993) 0.84
X-ray structure of native full-length human fibroblast-growth factor at 0.25-nm resolution. Eur J Biochem (1996) 0.84
Specific binding of the replication protein of plasmid pPS10 to direct and inverted repeats is mediated by an HTH motif. Nucleic Acids Res (1995) 0.83
Purification of a light-harvesting B880 complex from wild-type Rhodospirillum rubrum. Anal Biochem (1986) 0.83
Processing of yeast exoglucanase (beta-glucosidase) in a KEX2-dependent manner. FEBS Lett (1990) 0.82
A possible physiological function of the oxygen-photoreducing system of Rhodospirillum rubrum. Arch Microbiol (1976) 0.82
Solution structure and interaction with basic and acidic fibroblast growth factor of a 3-kDa human platelet factor-4 fragment with antiangiogenic activity. J Biol Chem (2001) 0.82
Three-dimensional structure of acidic fibroblast growth factor in solution: effects of binding to a heparin functional analog. J Mol Biol (1996) 0.82
1H NMR structural characterization of a nonmitogenic, vasodilatory, ischemia-protector and neuromodulatory acidic fibroblast growth factor. Biochemistry (2000) 0.82
Partial IGF affinity of circulating N- and C-terminal fragments of human insulin-like growth factor binding protein-4 (IGFBP-4) and the disulfide bonding pattern of the C-terminal IGFBP-4 domain. Biochemistry (2000) 0.81
Dobesilate diminishes activation of the mitogen-activated protein kinase ERK1/2 in glioma cells. J Cell Mol Med (2006) 0.81
Systemic administration of acidic fibroblast growth factor ameliorates the ischemic injury of the retina in rats. Neurosci Lett (1998) 0.81
1H-NMR assignment and solution structure of human acidic fibroblast growth factor activated by inositol hexasulfate. J Mol Biol (1994) 0.81
Isolation and characterization of a conditional replication mutant of the antibiotic resistance factor R1 affected in the gene of the replication protein repA. Mol Gen Genet (1989) 0.81
Functional interactions between homologous conditional killer systems of plasmid and chromosomal origin. FEMS Microbiol Lett (1997) 0.81
Acidic fibroblast growth factor prevents post-axotomy neuronal death of the newborn rat facial nerve. Neurosci Lett (1995) 0.81
Antiepileptic effects of acidic fibroblast growth factor examined in kainic acid-mediated seizures in the rat. Neurosci Lett (1996) 0.81
Single-step purification on DEAE-sephacel of recombinant polypeptides produced in Escherichia coli. Biotechnology (N Y) (1992) 0.81
Light-dependent ATP formation in a non-phototrophic mutant of Rhodospirillum rubrum deficient in oxygen photoreduction. Biochem Biophys Res Commun (1975) 0.81
Central nervous system distribution of fibroblast growth factor injected into the blood stream. Neurol Res (1996) 0.81
Two glycosylation patterns for a single protein (exoglucanase) in Saccharomyces cerevisiae. FEMS Microbiol Lett (1990) 0.80
Energetics of myo-inositol hexasulfate binding to human acidic fibroblast growth factor effect of ionic strength and temperature. Eur J Biochem (2000) 0.80
Immunohistochemical localization of basic fibroblast growth factor in choroid plexus of the rat. Neurol Res (1994) 0.80
Mechanism-based inactivation of alanine racemase by 3-halovinylglycines. J Biol Chem (1991) 0.80
Osteopromotion for cranioplasty: an experimental study in rats using acidic fibroblast growth factor. Surg Neurol (1997) 0.79
Effect of low pH and heparin on the structure of acidic fibroblast growth factor. Eur J Biochem (1994) 0.79
Fibroblast growth factors in myocardial ischemia / reperfusion injury and ischemic preconditioning. J Cell Mol Med (2002) 0.79
Acidic fibroblast growth factor inhibits junctional communication of Schwann cells in culture. Neurol Res (2000) 0.78
Intravenous fibroblast growth factor penetrates the blood-brain barrier and protects hippocampal neurons against ischemia-reperfusion injury. Surg Neurol (1998) 0.78
Spasmolytic effect of acidic fibroblast growth factor in early cerebral vasospasm in the rat. Surg Neurol (1998) 0.78
Abolished angiogenicity and tumorigenicity of rat glioma by 1-naphthalenemonosulfonate. Neurosci Lett (2001) 0.78
Coupling between reduced nicotinamide adenine dinucleotide oxidation and metabolite transport in renal brush border membrane vesicles. Biochemistry (1980) 0.78
A non-mitogenic form of acidic fibroblast growth factor reduces neutrophil infiltration in rat ischemic reperfused heart. Eur J Med Res (1997) 0.78
Destabilization, oligomerization and inhibition of the mitogenic activity of acidic fibroblast-growth factor by aurintricarboxylic acid. Eur J Biochem (1997) 0.78
Apoptosis of glioma cells induced by the fibroblast growth factor inhibitor 1,3,6-naphthalenetrisulfonate. Neurosci Lett (1999) 0.77
Role of fibroblast growth factors in neural trauma. Neurol Res (1997) 0.77
Acidic fibroblast growth factor rescues gerbil hippocampal neurons from ischemic apoptotic death. Neurol Res (1998) 0.77
Loss of basic fibroblast growth factor in the subcommissural organ of old spontaneously hypertensive rats. Neurosci Lett (1996) 0.77
Fibroblast growth factor protects the kidney against ischemia-reperfusion injury. Eur J Med Res (1999) 0.77
Single topical application of human recombinant basic fibroblast growth factor (rbFGF) promotes neovascularization in rat cerebral cortex. Surg Neurol (1993) 0.77
Occurrence of a reduced nicotinamide adenine dinucleotide oxidase activity linked to a cytochrome system in renal brush border membranes. Biochemistry (1980) 0.77
Inhibition of intra-tumoral angiogenesis and glioma growth by the fibroblast growth factor inhibitor 1,3,6-naphthalenetrisulfonate. Neurol Res (1999) 0.77
Fibroblast growth factor and hydrocephalus. Neurol Res (2000) 0.76
Neuroprotective effect of acidic fibroblast growth factor on seizure-associated brain damage. Neurol Res (1994) 0.76
Acidic fibroblast growth factor prevents death of spinal cord motoneurons in newborn rats after nerve section. Neurol Res (1995) 0.76
Kinins are implicated of the hypotensive effect of acidic fibroblast growth factor. Eur J Med Res (1997) 0.76
Synthesis of proteins with disulfide bonds in E. coli using defined culture media. Biotechniques (2002) 0.76
Sleep promoting effects of intravenously administered acidic fibroblast growth factor. Neurol Res (1996) 0.76
Suppression of acidic fibroblast growth factor-dependent angiogenesis by the antigrowth activity of 1,3,6-naphthalenetrisulfonate. Neurol Res (1999) 0.76
Topical treatment of actinic keratoses with potassium dobesilate 5% cream. a preliminary open-label study. Eur J Med Res (2011) 0.75
Durable recovery of the macular architecture and functionality of a diagnosed age-related macular degeneration 1 year after a single intravitreal injection of dobesilate. BMJ Case Rep (2013) 0.75
Serum levels of basic fibroblast growth factor in acute myocardial infarction. Eur J Med Res (1997) 0.75
Myo-inositol hexasulphate and low molecular weight heparin binding to human acidic fibroblast growth factor: a calorimetric and FTIR study. Int J Biol Macromol (2001) 0.75
Nitrergic innervation of rat brain vasculature. Neurol Res (1994) 0.75
Fibroblast growth factor and cerebral ischaemia. Neurol Res (1994) 0.75
Fibroblast growth factor decreases locomotor activity in rats. Neuroscience (1996) 0.75
Assignment of 1H and 15N resonances and secondary structure of the recombinant RicC3 of 2S albumin storage protein from Ricinus communis. J Biomol NMR (2002) 0.75
Cytochromes in the rat kidney brush border membrane. Biochem Biophys Res Commun (1978) 0.75
Analgesic effects of fibroblast growth factor in the rat. Neurosci Lett (1996) 0.75
Protective effects of acidic fibroblast growth factor against cardiac arrhythmias induced by ischemia and reperfusion in rats. Eur J Med Res (1997) 0.75