F Gisou van der Goot

Author PubWeight™ 78.79‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival. Cell 2006 4.63
2 Anthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent process. J Cell Biol 2003 3.97
3 Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins. Proc Natl Acad Sci U S A 2004 2.93
4 Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy. Cell Host Microbe 2009 2.52
5 Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol 2004 2.31
6 Mechanisms of pathogen entry through the endosomal compartments. Nat Rev Mol Cell Biol 2006 2.16
7 Activation of the unfolded protein response is required for defenses against bacterial pore-forming toxin in vivo. PLoS Pathog 2008 2.16
8 Differential sorting and fate of endocytosed GPI-anchored proteins. EMBO J 2002 2.15
9 Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis. J Cell Biol 2006 2.15
10 Initial steps of Shigella infection depend on the cholesterol/sphingolipid raft-mediated CD44-IpaB interaction. EMBO J 2002 1.99
11 Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies. PLoS Biol 2008 1.85
12 Anthrax toxin: the long and winding road that leads to the kill. Trends Microbiol 2005 1.68
13 Palmitoylation and ubiquitination regulate exit of the Wnt signaling protein LRP6 from the endoplasmic reticulum. Proc Natl Acad Sci U S A 2008 1.64
14 Pore formation: an ancient yet complex form of attack. Biochim Biophys Acta 2008 1.58
15 Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS One 2007 1.50
16 In-depth analysis of hyaline fibromatosis syndrome frameshift mutations at the same site reveal the necessity of personalized therapy. Hum Mutat 2013 1.45
17 Bacterial invasion via lipid rafts. Cell Microbiol 2005 1.42
18 Association of Helicobacter pylori vacuolating toxin (VacA) with lipid rafts. J Biol Chem 2002 1.41
19 Structure and assembly of pore-forming proteins. Curr Opin Struct Biol 2010 1.40
20 Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization. PLoS One 2008 1.38
21 Membrane injury by pore-forming proteins. Curr Opin Cell Biol 2009 1.36
22 Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptors. PLoS Pathog 2010 1.35
23 Requirement of N-glycan on GPI-anchored proteins for efficient binding of aerolysin but not Clostridium septicum alpha-toxin. EMBO J 2002 1.33
24 Pathogenic pore-forming proteins: function and host response. Cell Host Microbe 2012 1.31
25 A rivet model for channel formation by aerolysin-like pore-forming toxins. EMBO J 2006 1.28
26 Pore-forming toxins induce multiple cellular responses promoting survival. Cell Microbiol 2011 1.28
27 Molecular assembly of the aerolysin pore reveals a swirling membrane-insertion mechanism. Nat Chem Biol 2013 1.26
28 The role of the inflammasome in cellular responses to toxins and bacterial effectors. Semin Immunopathol 2007 1.25
29 What does S-palmitoylation do to membrane proteins? FEBS J 2013 1.23
30 Bacterial subversion of lipid rafts. Curr Opin Microbiol 2004 1.17
31 Extending the aerolysin family: from bacteria to vertebrates. PLoS One 2011 1.09
32 The dark sides of capillary morphogenesis gene 2. EMBO J 2011 1.08
33 Functional interactions between anthrax toxin receptors and the WNT signalling protein LRP6. Cell Microbiol 2008 1.06
34 Elastic membrane heterogeneity of living cells revealed by stiff nanoscale membrane domains. Biophys J 2007 1.05
35 Diversity of raft-like domains in late endosomes. PLoS One 2007 1.05
36 Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake. Proc Natl Acad Sci U S A 2010 1.03
37 Biochemical membrane lipidomics during Drosophila development. Dev Cell 2012 1.02
38 Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin. Cell Rep 2013 1.01
39 Caspase-2 is an initiator caspase responsible for pore-forming toxin-mediated apoptosis. EMBO J 2012 1.01
40 Dual chaperone role of the C-terminal propeptide in folding and oligomerization of the pore-forming toxin aerolysin. PLoS Pathog 2011 1.00
41 Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxin. Cell Microbiol 2008 0.95
42 The 2DX robot: a membrane protein 2D crystallization Swiss Army knife. J Struct Biol 2009 0.95
43 Sensitivity of polarized epithelial cells to the pore-forming toxin aerolysin. Infect Immun 2003 0.93
44 Novel ubiquitin-dependent quality control in the endoplasmic reticulum. Trends Cell Biol 2009 0.92
45 Dynamics of GPI-anchored proteins on the surface of living cells. Nanomedicine 2006 0.91
46 Systemic hyalinosis mutations in the CMG2 ectodomain leading to loss of function through retention in the endoplasmic reticulum. Hum Mutat 2009 0.88
47 About lipids and toxins. FEBS Lett 2006 0.83
48 Oiling the key hole. Mol Microbiol 2005 0.83
49 Calnexin controls the STAT3-mediated transcriptional response to EGF. Mol Cell 2013 0.82
50 Palmitoylation, pathogens and their host. Biochem Soc Trans 2013 0.81
51 Preliminary crystallographic analysis of two oligomerization-deficient mutants of the aerolysin toxin, H132D and H132N, in their proteolyzed forms. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.81
52 Eukaryotic cells and microbial pathogens: a familiar couple take centre stage. Nat Cell Biol 2003 0.77
53 Exotoxin secretion: getting out to find the way in. Cell Host Microbe 2008 0.76
54 A bacterial big-MAC attack. Nat Struct Mol Biol 2004 0.75
55 Toxoplasma: guess who's coming to dinner. Cell 2006 0.75
56 Did cholera toxin finally get caught? Cell Host Microbe 2013 0.75
57 When cells and microbes meet in Krakow. EMBO Rep 2011 0.75
58 Getting the Opportunity to Fly on your own. Chimia (Aarau) 2009 0.75