Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways.
|
Cell
|
2002
|
4.35
|
2
|
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload.
|
Circulation
|
2004
|
3.35
|
3
|
Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy.
|
Proc Natl Acad Sci U S A
|
2003
|
2.90
|
4
|
The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway.
|
J Biol Chem
|
2003
|
2.28
|
5
|
Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy.
|
Proc Natl Acad Sci U S A
|
2007
|
1.82
|
6
|
Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism.
|
Cardiovasc Res
|
2008
|
1.70
|
7
|
Analysis of liver metabolism in a rat model of heart failure.
|
Int J Cardiol
|
2011
|
1.68
|
8
|
Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy.
|
Mol Cell Biol
|
2004
|
1.43
|
9
|
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.
|
Cell Metab
|
2007
|
1.42
|
10
|
Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure.
|
Circ Heart Fail
|
2010
|
1.35
|
11
|
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance.
|
Mol Cell Biol
|
2008
|
1.33
|
12
|
PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.24
|
13
|
Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo.
|
Free Radic Biol Med
|
2005
|
1.17
|
14
|
Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice.
|
Circulation
|
2009
|
1.16
|
15
|
Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation.
|
Am J Pathol
|
2009
|
1.07
|
16
|
Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice.
|
J Mol Cell Cardiol
|
2011
|
1.03
|
17
|
Resistin, an adipocytokine, offers protection against acute myocardial infarction.
|
J Mol Cell Cardiol
|
2007
|
0.91
|
18
|
Resveratrol ameliorates experimental autoimmune myocarditis.
|
Circ J
|
2007
|
0.90
|
19
|
Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts.
|
J Mol Cell Cardiol
|
2013
|
0.90
|
20
|
Angiotensin II receptor antagonist attenuates expression of aging markers in diabetic mouse heart.
|
Circ J
|
2006
|
0.89
|
21
|
Attenuation of virus-induced myocardial injury by inhibition of the angiotensin II type 1 receptor signal and decreased nuclear factor-kappa B activation in knockout mice.
|
J Am Coll Cardiol
|
2003
|
0.89
|
22
|
Carvedilol increases the production of interleukin-12 and interferon-gamma and improves the survival of mice infected with the encephalomyocarditis virus.
|
J Am Coll Cardiol
|
2003
|
0.86
|
23
|
Phosphoinositide 3-kinase Akt signaling pathway interacts with protein kinase Cbeta2 in the regulation of physiologic developmental hypertrophy and heart function.
|
Am J Physiol Heart Circ Physiol
|
2009
|
0.86
|
24
|
Persistent overexpression of phosphoglycerate mutase, a glycolytic enzyme, modifies energy metabolism and reduces stress resistance of heart in mice.
|
PLoS One
|
2013
|
0.84
|
25
|
Rapamycin ameliorates experimental autoimmune myocarditis.
|
Int Heart J
|
2005
|
0.83
|
26
|
Percutaneous balloon valvuloplasty for bioprosthetic mitral valve stenosis.
|
Heart Vessels
|
2012
|
0.82
|
27
|
Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure.
|
Intern Med
|
2006
|
0.80
|
28
|
Inter- and intra-observer variability for assessment of the synergy between percutaneous coronary intervention with TAXUS and cardiac surgery (SYNTAX) score and association of the SYNTAX score with clinical outcome in patients undergoing unprotected left main stenting in the real world.
|
Circ J
|
2011
|
0.79
|
29
|
MicroRNA, emerging role as a biomarker of heart failure.
|
Circ J
|
2010
|
0.78
|
30
|
Impact of diabetes on cardiovascular outcomes in hemodialysis patients undergoing coronary revascularization.
|
Circ J
|
2011
|
0.76
|
31
|
Effect of persistent activation of phosphoinositide 3-kinase on heart.
|
Life Sci
|
2012
|
0.75
|
32
|
Long-term clinical outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease.
|
Cardiovasc Interv Ther
|
2014
|
0.75
|
33
|
Effects of machine-assisted cycling on exercise capacity and endothelial function in elderly patients with heart failure.
|
Circ J
|
2012
|
0.75
|