Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer.

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Published in Cell Div on January 17, 2010

Authors

C Elizabeth Caldon1, Elizabeth A Musgrove

Author Affiliations

1: Cancer Research Program, Garvan Institute of Medical Research, Sydney, NSW 2010, Australia. l.musgrove@garvan.org.au.

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res (1994) 392.47

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TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci (1996) 56.57

Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet (2005) 29.45

A microRNA component of the p53 tumour suppressor network. Nature (2007) 19.25

Rapid and sensitive sequence comparison with FASTP and FASTA. Methods Enzymol (1990) 17.64

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst (2006) 14.60

Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell (2009) 11.10

Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (1998) 8.75

Widespread occurrence of antisense transcription in the human genome. Nat Biotechnol (2003) 8.54

Rb targets histone H3 methylation and HP1 to promoters. Nature (2001) 8.26

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation. Nat Rev Cancer (2008) 7.93

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome. Genome Res (2006) 6.54

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes Dev (2001) 6.13

Cyclin E ablation in the mouse. Cell (2003) 5.58

Mammalian cyclin-dependent kinases. Trends Biochem Sci (2005) 5.54

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell (1991) 4.88

Deregulated cyclin E induces chromosome instability. Nature (1999) 4.75

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF. Cell (2000) 4.48

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell (1994) 4.07

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes. Mol Cell Biol (2004) 3.90

Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol (2005) 3.65

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miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res (2008) 3.19

Cyclin E in normal and neoplastic cell cycles. Oncogene (2005) 3.16

Kinase-independent function of cyclin E. Mol Cell (2007) 3.03

Cyclin E-induced S phase without activation of the pRb/E2F pathway. Genes Dev (1997) 3.02

Replication licensing and cancer--a fatal entanglement? Nat Rev Cancer (2008) 2.86

Endoreplication: polyploidy with purpose. Genes Dev (2009) 2.78

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MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma. Br J Cancer (2009) 2.57

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Androgens induce prostate cancer cell proliferation through mammalian target of rapamycin activation and post-transcriptional increases in cyclin D proteins. Cancer Res (2006) 2.46

ACTR/AIB1 functions as an E2F1 coactivator to promote breast cancer cell proliferation and antiestrogen resistance. Mol Cell Biol (2004) 2.46

Negative regulation of transcription by the type II arginine methyltransferase PRMT5. EMBO Rep (2002) 2.38

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