Published in Am J Clin Nutr on February 24, 2010
Muscle wasting in disease: molecular mechanisms and promising therapies. Nat Rev Drug Discov (2015) 1.90
Melanocortin antagonism ameliorates muscle wasting and inflammation in chronic kidney disease. Am J Physiol Renal Physiol (2012) 1.58
Functional Status, Time to Transplantation, and Survival Benefit of Kidney Transplantation Among Wait-Listed Candidates. Am J Kidney Dis (2015) 1.47
Physical performance and frailty in chronic kidney disease. Am J Nephrol (2013) 1.16
Baseline physical performance, health, and functioning of participants in the Frequent Hemodialysis Network (FHN) trial. Am J Kidney Dis (2011) 1.10
Exploring metabolic dysfunction in chronic kidney disease. Nutr Metab (Lond) (2012) 1.04
Calcineurin: a poorly understood regulator of muscle mass. Int J Biochem Cell Biol (2013) 0.99
Estimated net endogenous acid production and serum bicarbonate in African Americans with chronic kidney disease. Clin J Am Soc Nephrol (2011) 0.98
Aerobic training during hemodialysis improves body composition, muscle function, physical performance, and quality of life in chronic kidney disease patients. J Phys Ther Sci (2015) 0.93
Angiotensin II upregulates protein phosphatase 2Cα and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting. Hypertension (2011) 0.90
Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs. Am J Physiol Regul Integr Comp Physiol (2012) 0.89
Functional status and survival after kidney transplantation. Transplantation (2014) 0.89
Physical Activity in the Prevention of Chronic Kidney Disease. Cardiorenal Med (2011) 0.87
Decrease in urinary creatinine excretion in early stage chronic kidney disease. PLoS One (2014) 0.87
Akt1-mediated fast/glycolytic skeletal muscle growth attenuates renal damage in experimental kidney disease. J Am Soc Nephrol (2014) 0.87
Anabolic exercise in haemodialysis patients: a randomised controlled pilot study. J Cachexia Sarcopenia Muscle (2014) 0.86
Muscle torque relative to cross-sectional area and the functional muscle-bone unit in children and adolescents with chronic disease. J Bone Miner Res (2015) 0.85
Low-protein diets for chronic kidney disease patients: the Italian experience. BMC Nephrol (2016) 0.85
Sarcopenia: a major challenge in elderly patients with end-stage renal disease. J Aging Res (2012) 0.85
A higher alkaline dietary load is associated with greater indexes of skeletal muscle mass in women. Osteoporos Int (2012) 0.84
Early-stage chronic kidney disease, insulin resistance, and osteoporosis as risk factors of sarcopenia in aged population: the fourth Korea National Health and Nutrition Examination Survey (KNHANES IV), 2008-2009. Osteoporos Int (2014) 0.84
Uremic osteoporosis. Kidney Int Suppl (2011) (2013) 0.83
Estimating glomerular filtration rate in older people. Biomed Res Int (2014) 0.83
Connecting Myokines and Metabolism. Endocrinol Metab (Seoul) (2015) 0.82
Creatinine index as a surrogate of lean body mass derived from urea Kt/V, pre-dialysis serum levels and anthropometric characteristics of haemodialysis patients. PLoS One (2014) 0.82
Reduction in pulmonary function after CABG surgery is related to postoperative inflammation and hypercortisolemia. Int J Clin Exp Med (2015) 0.81
Transthyretin predicts cardiovascular outcome in hemodialysis patients with type 2 diabetes. Diabetes Care (2012) 0.81
Progressive inflammation and wasting in patients with ESRD. Clin J Am Soc Nephrol (2014) 0.80
Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function. Skelet Muscle (2014) 0.80
Dietary micronutrient intake in peritoneal dialysis patients: relationship with nutrition and inflammation status. Perit Dial Int (2011) 0.80
Low plasma α-tocopherol concentrations and adverse clinical outcomes in diabetic hemodialysis patients. Clin J Am Soc Nephrol (2013) 0.80
Cardiac function and tolerance to ischemia-reperfusion injury in chronic kidney disease. Nephrol Dial Transplant (2013) 0.80
Sarcopenia, obesity, and mortality in US adults with and without chronic kidney disease. KI Rep (2016) 0.80
Novel TAZ modulators enhance myogenic differentiation and muscle regeneration. Br J Pharmacol (2014) 0.79
Association of serum bicarbonate with incident functional limitation in older adults. Clin J Am Soc Nephrol (2014) 0.79
Natural history of skeletal muscle mass changes in chronic kidney disease stage 4 and 5 patients: an observational study. PLoS One (2013) 0.79
Skeletal muscle mitochondrial depletion and dysfunction in chronic kidney disease. Int J Clin Exp Med (2013) 0.78
Reduced skeletal muscle function is associated with decreased fiber cross-sectional area in the Cy/+ rat model of progressive kidney disease. Nephrol Dial Transplant (2015) 0.78
Muscle wasting in hemodialysis patients: new therapeutic strategies for resolving an old problem. ScientificWorldJournal (2013) 0.78
Dietary Intake of Proteins and Calories Is Inversely Associated With The Oxidation State of Plasma Thiols in End-Stage Renal Disease Patients. J Ren Nutr (2015) 0.77
Serum Glucocorticoid-Regulated Kinase 1 Blocks CKD-Induced Muscle Wasting Via Inactivation of FoxO3a and Smad2/3. J Am Soc Nephrol (2016) 0.77
Pulmonary function and exercise tolerance are related to disease severity in pre-dialytic patients with chronic kidney disease: a cross-sectional study. BMC Nephrol (2013) 0.76
Physical inactivity: a risk factor and target for intervention in renal care. Nat Rev Nephrol (2017) 0.75
Changes in Body Composition in the Two Years after Initiation of Haemodialysis: A Retrospective Cohort Study. Nutrients (2016) 0.75
Skeletal Muscle Regeneration and Oxidative Stress Are Altered in Chronic Kidney Disease. PLoS One (2016) 0.75
The role of bicarbonate in CKD: evidence bulks up. Clin J Am Soc Nephrol (2013) 0.75
Prevalence and predictors of low muscle mass in HIV/viral hepatitis coinfection. AIDS (2016) 0.75
Six-Minute Walk Test in Renal Failure Patients: Representative Results, Performance Analysis and Perceived Dyspnea Predictors. PLoS One (2016) 0.75
Acid-base balance and physical function. Clin J Am Soc Nephrol (2014) 0.75
Gender-specific association between dietary acid load and total lean body mass and its dependency on protein intake in seniors. Osteoporos Int (2017) 0.75
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J (2004) 7.02
Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension. J Clin Invest (2003) 6.30
Cachexia: a new definition. Clin Nutr (2008) 5.49
Proteinuria, a target for renoprotection in patients with type 2 diabetic nephropathy: lessons from RENAAL. Kidney Int (2004) 4.51
Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol (2006) 4.01
Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation (2004) 3.78
Activation of caspase-3 is an initial step triggering accelerated muscle proteolysis in catabolic conditions. J Clin Invest (2004) 2.98
Insulin resistance accelerates muscle protein degradation: Activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology (2006) 2.62
The risk of developing end-stage renal disease in patients with type 2 diabetes and nephropathy: the RENAAL study. Kidney Int (2003) 2.43
Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study. Clin J Am Soc Nephrol (2006) 2.37
Relationships among inflammation nutrition and physiologic mechanisms establishing albumin levels in hemodialysis patients. Kidney Int (2002) 2.27
Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. J Clin Invest (2005) 2.24
Regulation of muscle protein degradation: coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. J Am Soc Nephrol (2004) 2.13
IL-6 and serum amyloid A synergy mediates angiotensin II-induced muscle wasting. J Am Soc Nephrol (2009) 1.88
Etiology of the protein-energy wasting syndrome in chronic kidney disease: a consensus statement from the International Society of Renal Nutrition and Metabolism (ISRNM). J Ren Nutr (2013) 1.85
Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: implications for muscle atrophy. J Am Soc Nephrol (2006) 1.82
The precision of estimating protein intake of patients with chronic renal failure. Kidney Int (2002) 1.81
Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. J Am Soc Nephrol (2010) 1.77
Pharmacological inhibition of myostatin suppresses systemic inflammation and muscle atrophy in mice with chronic kidney disease. FASEB J (2011) 1.67
Requirement of argininosuccinate lyase for systemic nitric oxide production. Nat Med (2011) 1.54
Endogenous glucocorticoids and impaired insulin signaling are both required to stimulate muscle wasting under pathophysiological conditions in mice. J Clin Invest (2009) 1.51
Stat3 activation links a C/EBPδ to myostatin pathway to stimulate loss of muscle mass. Cell Metab (2013) 1.49
OPPORTUNITY™: a large-scale randomized clinical trial of growth hormone in hemodialysis patients. Nephrol Dial Transplant (2011) 1.44
Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients. Kidney Int (2004) 1.40
Myostatin/activin pathway antagonism: molecular basis and therapeutic potential. Int J Biochem Cell Biol (2013) 1.32
Nutrition in CAPD: serum bicarbonate and the ubiquitin-proteasome system in muscle. Kidney Int (2002) 1.31
Chemokine CXCL16 regulates neutrophil and macrophage infiltration into injured muscle, promoting muscle regeneration. Am J Pathol (2009) 1.30
Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile. Endocrinology (2007) 1.23
Exercise ameliorates chronic kidney disease-induced defects in muscle protein metabolism and progenitor cell function. Kidney Int (2009) 1.17
Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions. J Am Soc Nephrol (2006) 1.15
Decreased miR-29 suppresses myogenesis in CKD. J Am Soc Nephrol (2011) 1.15
Caspase-3 cleaves specific 19 S proteasome subunits in skeletal muscle stimulating proteasome activity. J Biol Chem (2010) 1.14
PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes (2007) 1.12
Ubiquitin (UbC) expression in muscle cells is increased by glucocorticoids through a mechanism involving Sp1 and MEK1. J Biol Chem (2002) 1.07
PTEN inhibition improves muscle regeneration in mice fed a high-fat diet. Diabetes (2010) 1.07
Blocking Notch in endothelial cells prevents arteriovenous fistula failure despite CKD. J Am Soc Nephrol (2014) 1.04
Muscle wasting from kidney failure-a model for catabolic conditions. Int J Biochem Cell Biol (2013) 1.00
Signal regulatory protein-α interacts with the insulin receptor contributing to muscle wasting in chronic kidney disease. Kidney Int (2013) 0.98
Effect of bicarbonate on muscle protein in patients receiving hemodialysis. Am J Kidney Dis (2006) 0.97
Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia. Int J Biochem Cell Biol (2013) 0.97
Targeting the myostatin signaling pathway to treat muscle wasting diseases. Curr Opin Support Palliat Care (2011) 0.96
Keto acid therapy in predialysis chronic kidney disease patients: final consensus. J Ren Nutr (2012) 0.95
Proteolysis by the ubiquitin-proteasome system and kidney disease. J Am Soc Nephrol (2011) 0.93
Angiotensin II upregulates protein phosphatase 2Cα and inhibits AMP-activated protein kinase signaling and energy balance leading to skeletal muscle wasting. Hypertension (2011) 0.90
Protein-restricted diets plus keto/amino acids--a valid therapeutic approach for chronic kidney disease patients. J Ren Nutr (2012) 0.90
Muscle wasting in chronic kidney disease: the role of the ubiquitin proteasome system and its clinical impact. Pediatr Nephrol (2007) 0.90
Dietary protein restriction benefits patients with chronic kidney disease. Nephrology (Carlton) (2006) 0.90
MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways. Aging (Albany NY) (2014) 0.89
The mean dietary protein intake at different stages of chronic kidney disease is higher than current guidelines. Kidney Int (2013) 0.87
Ubiquitin, proteasomes and proteolytic mechanisms activated by kidney disease. Biochim Biophys Acta (2008) 0.87
A report with consensus statements of the International Society of Nephrology 2004 Consensus Workshop on Prevention of Progression of Renal Disease, Hong Kong, June 29, 2004. Kidney Int Suppl (2005) 0.87
Tissue-specific regulation of ubiquitin (UbC) transcription by glucocorticoids: in vivo and in vitro analyses. Am J Physiol Renal Physiol (2006) 0.86
Cellular signals activating muscle proteolysis in chronic kidney disease: a two-stage process. Int J Biochem Cell Biol (2005) 0.84
Loss of glutathione S-transferase A4 accelerates obstruction-induced tubule damage and renal fibrosis. J Pathol (2012) 0.83
Mechanisms stimulating muscle wasting in chronic kidney disease: the roles of the ubiquitin-proteasome system and myostatin. Clin Exp Nephrol (2013) 0.82
Navigating between the Scylla and Charybdis of prescribing dietary protein for chronic kidney diseases. Annu Rev Nutr (2009) 0.80
Impact of albumin synthesis rate and the acute phase response in the dual regulation of fibrinogen levels in hemodialysis patients. Kidney Int (2003) 0.80
Influence of renal function and diet on acid-base status in chronic kidney disease patients. J Ren Nutr (2009) 0.80
The evidence against malnutrition as a prominent problem for chronic dialysis patients. Semin Dial (2005) 0.79
Identification of pathways controlling muscle protein metabolism in uremia and other catabolic conditions. Curr Opin Nephrol Hypertens (2005) 0.79
OPPORTUNITY: a randomized clinical trial of growth hormone on outcome in hemodialysis patients. Clin J Am Soc Nephrol (2008) 0.78
Proteins and renal fibrosis: low-protein diets induce Kruppel-like factor-15, limiting renal fibrosis. Kidney Int (2011) 0.78
Evidence that C-reactive protein or IL-6 are not surrogates for all inflammatory cardiovascular risk factors in hemodialysis patients. Blood Purif (2006) 0.77
The dilemma of diagnosing the cause of hypernatraemia: drinking habits vs diabetes insipidus. Nephrol Dial Transplant (2004) 0.77
FSP-1 Impairs the Function of Endothelium Leading to Failure of Arteriovenous Grafts in Diabetic Mice. Endocrinology (2015) 0.75
Is cystatin C more effective than creatinine in predicting adverse cardiovascular outcomes in elderly people? Nat Clin Pract Nephrol (2005) 0.75
High-protein diet in diabetic nephropathy: what is really safe? Am J Clin Nutr (2013) 0.75
Getting beyond cross-sectional studies of abnormal nutritional indexes in dialysis patients. Am J Clin Nutr (2003) 0.75
Adverse Effects of Sporadic Dialysis on Body Composition. Nephron (2015) 0.75
Protein catabolism in chronic uremia: is it due to malnutrition? Arch Immunol Ther Exp (Warsz) (2004) 0.75
Prevention Conference VI: Diabetes and Cardiovascular Disease: Writing Group V: management of cardiovascular-renal complications. Circulation (2002) 0.75
Parathyroid hormone stimulates adipose tissue browning: a pathway to muscle wasting. Curr Opin Clin Nutr Metab Care (2017) 0.75
A dedication to Alfred L. Goldberg. Int J Biochem Cell Biol (2013) 0.75