Published in J Biol Chem on February 24, 2010
Force fluctuations within focal adhesions mediate ECM-rigidity sensing to guide directed cell migration. Cell (2012) 2.87
Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth. J Cell Biol (2013) 1.63
Dimensions in cell migration. Curr Opin Cell Biol (2013) 1.36
Fibroblasts and the ground they walk on. Physiology (Bethesda) (2013) 1.34
Force engages vinculin and promotes tumor progression by enhancing PI3K activation of phosphatidylinositol (3,4,5)-triphosphate. Cancer Res (2014) 1.21
Patterned differentiation of individual embryoid bodies in spatially organized 3D hybrid microgels. Adv Mater (2010) 1.18
Delayed wound closure in fibromodulin-deficient mice is associated with increased TGF-β3 signaling. J Invest Dermatol (2010) 1.07
In situ mechanotransduction via vinculin regulates stem cell differentiation. Stem Cells (2013) 1.05
Paxillin and Hic-5 interaction with vinculin is differentially regulated by Rac1 and RhoA. PLoS One (2012) 1.00
Proteomic patterns of cervical cancer cell lines, a network perspective. BMC Syst Biol (2011) 0.96
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS One (2012) 0.93
Myosin II activity dependent and independent vinculin recruitment to the sites of E-cadherin-mediated cell-cell adhesion. BMC Cell Biol (2011) 0.93
What is vinculin needed for in platelets? J Thromb Haemost (2010) 0.90
The difference of fibroblast behavior on titanium substrata with different surface characteristics. Odontology (2011) 0.89
The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin. PLoS One (2010) 0.87
Binding of the WASP/N-WASP-interacting protein WIP to actin regulates focal adhesion assembly and adhesion. Mol Cell Biol (2014) 0.87
CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics. Cell Mol Life Sci (2013) 0.86
Extracellular matrix collagen alters cell proliferation and cell cycle progression of human uterine leiomyoma smooth muscle cells. PLoS One (2013) 0.85
Vinculin phosphorylation at residues Y100 and Y1065 is required for cellular force transmission. J Cell Sci (2015) 0.84
Migration in Confined 3D Environments Is Determined by a Combination of Adhesiveness, Nuclear Volume, Contractility, and Cell Stiffness. Biophys J (2015) 0.84
Vinculin is required for cell polarization, migration, and extracellular matrix remodeling in 3D collagen. FASEB J (2015) 0.84
Monomeric and dimeric conformation of the vinculin tail five-helix bundle in solution studied by EPR spectroscopy. Biophys J (2011) 0.83
Occupy tissue: the movement in cancer metastasis. Cell Adh Migr (2012) 0.83
Taking a deep look: modern microscopy technologies to optimize the design and functionality of biocompatible scaffolds for tissue engineering in regenerative medicine. J R Soc Interface (2013) 0.83
Biomembrane-mimicking lipid bilayer system as a mechanically tunable cell substrate. Biomaterials (2014) 0.83
Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancer. Mol Cancer (2014) 0.81
Investigating lasp-2 in cell adhesion: new binding partners and roles in motility. Mol Biol Cell (2013) 0.80
HAb18G/CD147 regulates vinculin-mediated focal adhesion and cytoskeleton organization in cultured human hepatocellular carcinoma cells. PLoS One (2014) 0.80
Drosophila integrin adhesion complexes are essential for hemocyte migration in vivo. Biol Open (2013) 0.80
Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks. J Cell Sci (2015) 0.78
Physical view on migration modes. Cell Adh Migr (2015) 0.77
Porous three-dimensional carbon nanotube scaffolds for tissue engineering. J Biomed Mater Res A (2015) 0.77
Vinculin Regulates Directionality and Cell Polarity in 2D, 3D Matrix and 3D Microtrack Migration. Mol Biol Cell (2016) 0.77
Mechanosensing via cell-matrix adhesions in 3D microenvironments. Exp Cell Res (2015) 0.77
Integrin-mediated internalization of Staphylococcus aureus does not require vinculin. BMC Cell Biol (2013) 0.76
Boyden chamber-based method for characterizing the distribution of adhesions and cytoskeletal structure in HT1080 fibrosarcoma cells. Cell Adh Migr (2014) 0.76
Bacillus cereus Certhrax ADP-ribosylates vinculin to disrupt focal adhesion complexes and cell adhesion. J Biol Chem (2014) 0.76
Slow cryopreservation is not superior to vitrification in human spermatozoa; an experimental controlled study. Iran J Reprod Med (2015) 0.75
Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior. PLoS One (2017) 0.75
Focal adhesion kinase activity is required for actomyosin contractility-based invasion of cells into dense 3D matrices. Sci Rep (2017) 0.75
GAR22β regulates cell migration, sperm motility, and axoneme structure. Mol Biol Cell (2015) 0.75
Effect of laser-dimpled titanium surfaces on attachment of epithelial-like cells and fibroblasts. J Adv Prosthodont (2015) 0.75
Inherent aggressive character of invasive and non-invasive cells dictates the in vitro migration pattern of multicellular spheroid. Sci Rep (2017) 0.75
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Role of vinculin in regulating focal adhesion turnover. Eur J Cell Biol (2006) 2.03
Mechano-coupling and regulation of contractility by the vinculin tail domain. Biophys J (2007) 1.92
Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility. J Cell Biol (2004) 1.83
Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. Proc Natl Acad Sci U S A (1995) 1.82
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Breakdown of the endothelial barrier function in tumor cell transmigration. Biophys J (2007) 1.39
Illuminating adhesion complexes in migrating cells: moving toward a bright future. Curr Opin Cell Biol (2003) 1.39
Contractile forces in tumor cell migration. Eur J Cell Biol (2008) 1.31
High-force magnetic tweezers with force feedback for biological applications. Rev Sci Instrum (2007) 1.29
Becoming stable and strong: the interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation. Cell Motil Cytoskeleton (2009) 1.14
Membrane type-1 matrix metalloproteinase (MT1-MMP) processing of pro-alphav integrin regulates cross-talk between alphavbeta3 and alpha2beta1 integrins in breast carcinoma cells. Exp Cell Res (2003) 1.13
Remodeling of the airway smooth muscle cell: are we built of glass? Respir Physiol Neurobiol (2003) 1.12
Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus. Clin Orthop Relat Res (2008) 1.11
Motility of vinculin-deficient F9 embryonic carcinoma cells analyzed by video, laser confocal, and reflection interference contrast microscopy. Exp Cell Res (1995) 1.10
Traction fields, moments, and strain energy that cells exert on their surroundings. Am J Physiol Cell Physiol (2002) 6.39
Microrheology of human lung epithelial cells measured by atomic force microscopy. Biophys J (2003) 3.46
Cytoskeletal remodelling and slow dynamics in the living cell. Nat Mater (2005) 3.42
Single-cell response to stiffness exhibits muscle-like behavior. Proc Natl Acad Sci U S A (2009) 2.11
Intracellular stress tomography reveals stress focusing and structural anisotropy in cytoskeleton of living cells. Am J Physiol Cell Physiol (2003) 2.09
Robust pore size analysis of filamentous networks from three-dimensional confocal microscopy. Biophys J (2008) 2.03
Mechano-coupling and regulation of contractility by the vinculin tail domain. Biophys J (2007) 1.92
Do biophysical properties of the airway smooth muscle in culture predict airway hyperresponsiveness? Am J Respir Cell Mol Biol (2006) 1.78
Rheology of airway smooth muscle cells is associated with cytoskeletal contractile stress. J Appl Physiol (1985) (2004) 1.77
3D Traction forces in cancer cell invasion. PLoS One (2012) 1.76
Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle. EMBO J (2004) 1.73
Mapping and consensus sequence identification for multiple vinculin binding sites within the talin rod. J Biol Chem (2005) 1.68
A finite element model of cell deformation during magnetic bead twisting. J Appl Physiol (1985) (2002) 1.68
Vinculin acts as a sensor in lipid regulation of adhesion-site turnover. J Cell Sci (2005) 1.66
Integrin α5β1 facilitates cancer cell invasion through enhanced contractile forces. J Cell Sci (2011) 1.59
Neutrophil morphology and migration are affected by substrate elasticity. Blood (2009) 1.53
Cytoskeleton dynamics: fluctuations within the network. Biochem Biophys Res Commun (2007) 1.50
Structural and dynamic characterization of a vinculin binding site in the talin rod. Biochemistry (2006) 1.40
Breakdown of the endothelial barrier function in tumor cell transmigration. Biophys J (2007) 1.39
Airway hyperresponsiveness, remodeling, and smooth muscle mass: right answer, wrong reason? Am J Respir Cell Mol Biol (2007) 1.39
Molecular pathophysiology of mucolipidosis type IV: pH dysregulation of the mucolipin-1 cation channel. Hum Mol Genet (2004) 1.37
Cytoskeletal mechanics in adherent human airway smooth muscle cells: probe specificity and scaling of protein-protein dynamics. Am J Physiol Cell Physiol (2004) 1.36
Strain history dependence of the nonlinear stress response of fibrin and collagen networks. Proc Natl Acad Sci U S A (2013) 1.35
Structural determinants of integrin binding to the talin rod. J Biol Chem (2009) 1.35
Contractile forces in tumor cell migration. Eur J Cell Biol (2008) 1.31
High-force magnetic tweezers with force feedback for biological applications. Rev Sci Instrum (2007) 1.29
Stress fluctuations and motion of cytoskeletal-bound markers. Phys Rev E Stat Nonlin Soft Matter Phys (2007) 1.28
The role of the tissue microenvironment in the regulation of cancer cell motility and invasion. Cell Commun Signal (2010) 1.27
Rat airway smooth muscle cell during actin modulation: rheology and glassy dynamics. Am J Physiol Cell Physiol (2005) 1.25
Feeling the forces: atomic force microscopy in cell biology. Life Sci (2003) 1.23
Huntingtin associates with acidic phospholipids at the plasma membrane. J Biol Chem (2005) 1.22
Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell. J Appl Physiol (1985) (2004) 1.22
The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha. J Biol Chem (2003) 1.20
The multimeric structure of polycystin-2 (TRPP2): structural-functional correlates of homo- and hetero-multimers with TRPC1. Hum Mol Genet (2009) 1.17
Dynamic equilibration of airway smooth muscle contraction during physiological loading. J Appl Physiol (1985) (2002) 1.16
Architecture of the osteocyte network correlates with bone material quality. J Bone Miner Res (2013) 1.15
Localized mechanical stress induces time-dependent actin cytoskeletal remodeling and stiffening in cultured airway smooth muscle cells. Am J Physiol Cell Physiol (2004) 1.14
Up-regulation of Rho/ROCK signaling in sarcoma cells drives invasion and increased generation of protrusive forces. Mol Cancer Res (2008) 1.14
Becoming stable and strong: the interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation. Cell Motil Cytoskeleton (2009) 1.14
A blind spot in confocal reflection microscopy: the dependence of fiber brightness on fiber orientation in imaging biopolymer networks. Biophys J (2010) 1.13
Integrin adhesion and force coupling are independently regulated by localized PtdIns(4,5)2 synthesis. EMBO J (2011) 1.12
On the terminology for describing the length-force relationship and its changes in airway smooth muscle. J Appl Physiol (1985) (2004) 1.12
CD24 induces localization of beta1 integrin to lipid raft domains. Biochem Biophys Res Commun (2007) 1.08
Cation channel activity of mucolipin-1: the effect of calcium. Pflugers Arch (2005) 1.04
Focal adhesion kinase stabilizes the cytoskeleton. Biophys J (2011) 1.04
Geometry as a factor for tissue growth: towards shape optimization of tissue engineering scaffolds. Adv Healthc Mater (2012) 1.02
Coordinated movements prevent jamming in an Emperor penguin huddle. PLoS One (2011) 1.01
Evidence for direct interaction between actin and the cystic fibrosis transmembrane conductance regulator. Eur Biophys J (2002) 1.00
Cell and tissue mechanics in cell migration. Exp Cell Res (2013) 1.00
Vinculin, cell mechanics and tumour cell invasion. Cell Biol Int (2013) 1.00
Control of high affinity interactions in the talin C terminus: how talin domains coordinate protein dynamics in cell adhesions. J Biol Chem (2009) 0.99
Anchorage of vinculin to lipid membranes influences cell mechanical properties. Biophys J (2009) 0.99
Fractional derivatives embody essential features of cell rheological behavior. Ann Biomed Eng (2003) 0.97
Biomechanical characterization of a desminopathy in primary human myoblasts. Biochem Biophys Res Commun (2012) 0.95
A simplified implementation of the bubble analysis of biopolymer network pores. Biophys J (2013) 0.95
Acquisition of paclitaxel resistance is associated with a more aggressive and invasive phenotype in prostate cancer. J Cell Biochem (2013) 0.94
NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration. PLoS One (2012) 0.93
How linear tension converts to curvature: geometric control of bone tissue growth. PLoS One (2012) 0.92
Mineralization kinetics in murine trabecular bone quantified by time-lapsed in vivo micro-computed tomography. Bone (2013) 0.91
Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle. J Clin Invest (2014) 0.91
Estimating the 3D pore size distribution of biopolymer networks from directionally biased data. Biophys J (2013) 0.91
Quantifying cell-to-cell variation in power-law rheology. Biophys J (2013) 0.90
Head/tail interaction of vinculin influences cell mechanical behavior. Biochem Biophys Res Commun (2011) 0.90
Phosphorylation of actin-binding protein (ABP-280; filamin) by tyrosine kinase p56lck modulates actin filament cross-linking. Cell Biol Int (2004) 0.89
Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001. Biochem Pharmacol (2011) 0.88
The vinculin-DeltaIn20/21 mouse: characteristics of a constitutive, actin-binding deficient splice variant of vinculin. PLoS One (2010) 0.87
Control of magnesium corrosion and biocompatibility with biomimetic coatings. J Biomed Mater Res B Appl Biomater (2011) 0.87
CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics. Cell Mol Life Sci (2013) 0.86
Parameter-free binarization and skeletonization of fiber networks from confocal image stacks. PLoS One (2012) 0.86
Protein-lipid interactions: correlation of a predictive algorithm for lipid-binding sites with three-dimensional structural data. Theor Biol Med Model (2006) 0.86
Direct evidence of vinculin tail-lipid membrane interaction in beta-sheet conformation. Biochem Biophys Res Commun (2008) 0.85
Binding Affinity of Metal Ions to the CD11b A-domain Is Regulated by Integrin Activation and Ligands. J Biol Chem (2004) 0.85
Effect of surface pre-treatments on biocompatibility of magnesium. Acta Biomater (2009) 0.85
Tyrosine phosphorylation of vinculin at position 1065 modifies focal adhesion dynamics and cell tractions. Biochem Biophys Res Commun (2010) 0.84
Comparing the mechanical influence of vinculin, focal adhesion kinase and p53 in mouse embryonic fibroblasts. Biochem Biophys Res Commun (2009) 0.84
Identification of DAPK as a scaffold protein for the LIMK/cofilin complex in TNF-induced apoptosis. Int J Biochem Cell Biol (2013) 0.84
Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers. Biochem Biophys Res Commun (2009) 0.83
Monomeric and dimeric conformation of the vinculin tail five-helix bundle in solution studied by EPR spectroscopy. Biophys J (2011) 0.83
Anodic mesoporous TiO2 layer on Ti for enhanced formation of biomimetic hydroxyapatite. Acta Biomater (2010) 0.83
Occupy tissue: the movement in cancer metastasis. Cell Adh Migr (2012) 0.83
Thermodynamic evidence of non-muscle myosin II-lipid-membrane interaction. Biochem Biophys Res Commun (2007) 0.82
Vinculin's C-terminal region facilitates phospholipid membrane insertion. Biochem Biophys Res Commun (2010) 0.82