Published in Stroke on February 25, 2010
Study of Tenecteplase (TNK) in Acute Ischemic Stroke (TNK-S2B) | NCT00252239
Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) (TALISMAN) | NCT02180204
Low-Dose Tenecteplase in Covid-19 Diagnosed With Pulmonary Embolism | NCT04558125
The Norwegian tenecteplase stroke trial (NOR-TEST): randomised controlled trial of tenecteplase vs. alteplase in acute ischaemic stroke. BMC Neurol (2014) 1.02
Adjunctive and alternative approaches to current reperfusion therapy. Stroke (2012) 1.00
Review of stroke thrombolytics. J Stroke (2013) 0.98
A fibrin-specific thrombolytic nanomedicine approach to acute ischemic stroke. Nanomedicine (Lond) (2011) 0.90
Rationale for a nanomedicine approach to thrombolytic therapy. Stroke (2010) 0.84
Effect of waivers of consent on recruitment in acute stroke trials: A systematic review. Neurology (2016) 0.83
Fast neuroprotection (fast-NPRX) for acute ischemic stroke victims: the time for treatment is now. Transl Stroke Res (2013) 0.82
Reperfusion therapies of acute ischemic stroke: potentials and failures. Front Neurol (2014) 0.81
Intravenous thrombolytics for ischemic stroke. Neurotherapeutics (2011) 0.81
Intra-arterial therapy for acute ischemic stroke. Neurotherapeutics (2011) 0.81
A pragmatic approach to sonothrombolysis in acute ischaemic stroke: the Norwegian randomised controlled sonothrombolysis in acute stroke study (NOR-SASS). BMC Neurol (2015) 0.81
Neuroimaging as a Selection Tool and Endpoint in Clinical and Pre-clinical Trials. Transl Stroke Res (2016) 0.80
Drug treatment of acute ischemic stroke. Am J Cardiovasc Drugs (2013) 0.80
Reperfusion therapies for acute ischemic stroke: an update. Curr Cardiol Rev (2014) 0.79
Intra-arterial therapy for acute ischemic stroke. Interv Neurol (2013) 0.79
Intravenous tenecteplase in acute ischemic stroke: an updated review. J Neurol (2013) 0.78
What is the Role for Intra-Arterial Therapy in Acute Stroke Intervention? Neurohospitalist (2015) 0.78
Statistical aspects of the TNK-S2B trial of tenecteplase versus alteplase in acute ischemic stroke: an efficient, dose-adaptive, seamless phase II/III design. Clin Trials (2011) 0.77
Quantification of errors in ordinal outcome scales using shannon entropy: effect on sample size calculations. PLoS One (2013) 0.77
Advances in medical revascularisation treatments in acute ischemic stroke. Thrombosis (2014) 0.76
Fibrinolysis and Beyond: Bridging the Gap between Local and Systemic Clot Removal. Front Neurol (2011) 0.75
Efficiency of enrollment in a successful phase II acute stroke clinical trial. J Stroke Cerebrovasc Dis (2011) 0.75
Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke (1993) 29.81
Interobserver agreement for the assessment of handicap in stroke patients. Stroke (1988) 20.14
Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial. Lancet (1999) 4.36
Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic stroke. Ann Emerg Med (2005) 4.04
A pilot dose-escalation safety study of tenecteplase in acute ischemic stroke. Stroke (2005) 1.83
NIHSS training and certification using a new digital video disk is reliable. Stroke (2005) 1.53
Predicting major neurological improvement with intravenous recombinant tissue plasminogen activator treatment of stroke. Stroke (2003) 1.21
Acute ischemic stroke: imaging-guided tenecteplase treatment in an extended time window. Neurology (2009) 1.14
Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet (2004) 12.92
Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet (2010) 12.21
Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med (2005) 7.92
Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2010) 6.93
Warfarin and aspirin in patients with heart failure and sinus rhythm. N Engl J Med (2012) 6.60
Selecting the right tool for the job. Am J Bioeth (2015) 6.11
Ultrasound-enhanced systemic thrombolysis for acute ischemic stroke. N Engl J Med (2004) 5.32
Relapse risk after discontinuation of risperidone in Alzheimer's disease. N Engl J Med (2012) 4.22
Predictors of ischemic stroke in the territory of a symptomatic intracranial arterial stenosis. Circulation (2006) 4.21
Guidelines for the early management of patients with ischemic stroke: A scientific statement from the Stroke Council of the American Stroke Association. Stroke (2003) 4.13
Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoS Biol (2006) 3.77
Excess stroke in Mexican Americans compared with non-Hispanic Whites: the Brain Attack Surveillance in Corpus Christi Project. Am J Epidemiol (2004) 3.69
"Fundamental causes" of social inequalities in mortality: a test of the theory. J Health Soc Behav (2004) 3.67
Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke. JAMA (2004) 3.51
Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nat Methods (2006) 3.28
Efficacy of site-independent telemedicine in the STRokE DOC trial: a randomised, blinded, prospective study. Lancet Neurol (2008) 3.18
Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels. J Neurosci (2009) 3.10
Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts. Cancer Epidemiol Biomarkers Prev (2002) 2.83
National Stroke Association guidelines for the management of transient ischemic attacks. Ann Neurol (2006) 2.82
A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke (2009) 2.74
Stroke among patients with dizziness, vertigo, and imbalance in the emergency department: a population-based study. Stroke (2006) 2.73
Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. Circulation (2002) 2.71
The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer. Breast Cancer Res Treat (2002) 2.71
Penetrating arterioles are a bottleneck in the perfusion of neocortex. Proc Natl Acad Sci U S A (2006) 2.71
Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet (2009) 2.50
Neurological, functional, and cognitive stroke outcomes in Mexican Americans. Stroke (2014) 2.48
IV magnesium sulfate in the treatment of acute severe asthma: a multicenter randomized controlled trial. Chest (2002) 2.38
Variants at APOE influence risk of deep and lobar intracerebral hemorrhage. Ann Neurol (2010) 2.31
Intravenous thrombolysis plus hypothermia for acute treatment of ischemic stroke (ICTuS-L): final results. Stroke (2010) 2.29
A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotroph Lateral Scler (2008) 2.28
Recommendations for the implementation of telemedicine within stroke systems of care: a policy statement from the American Heart Association. Stroke (2009) 2.26
Comparison of warfarin versus aspirin for the prevention of recurrent stroke or death: subgroup analyses from the Warfarin-Aspirin Recurrent Stroke Study. Cerebrovasc Dis (2006) 2.19
Arterial reocclusion in stroke patients treated with intravenous tissue plasminogen activator. Neurology (2002) 2.18
Use of a rapid HIV home test to screen sexual partners: an evaluation of its possible use and relative risk. AIDS Behav (2009) 2.12
Houston paramedic and emergency stroke treatment and outcomes study (HoPSTO). Stroke (2005) 2.12
Hematoma resolution as a target for intracerebral hemorrhage treatment: role for peroxisome proliferator-activated receptor gamma in microglia/macrophages. Ann Neurol (2007) 2.05
Superficial siderosis: a case report and review of the literature. Nat Clin Pract Neurol (2007) 2.05
Stroke risk after nonstroke emergency department dizziness presentations: a population-based cohort study. Ann Neurol (2014) 2.02
Improving delivery of acute stroke therapy: The TLL Temple Foundation Stroke Project. Stroke (2002) 1.97
Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model. J Neurosci Res (2010) 1.89
Applying a phase II futility study design to therapeutic stroke trials. Stroke (2005) 1.89
Stroke risk after transient ischemic attack in a population-based setting. Stroke (2004) 1.88
A pilot dose-escalation safety study of tenecteplase in acute ischemic stroke. Stroke (2005) 1.83
Is it time for a large, collaborative study of pediatric stroke? Stroke (2005) 1.83
Induced hypothermia for acute stroke. Stroke (2007) 1.82
Selecting promising ALS therapies in clinical trials. Neurology (2006) 1.80
Autologous bone marrow mononuclear cells enhance recovery after acute ischemic stroke in young and middle-aged rats. J Cereb Blood Flow Metab (2009) 1.80
Persistent ischemic stroke disparities despite declining incidence in Mexican Americans. Ann Neurol (2013) 1.79
Anticoagulation after cardioembolic stroke: to bridge or not to bridge? Arch Neurol (2008) 1.79
The combined approach to lysis utilizing eptifibatide and rt-PA in acute ischemic stroke: the CLEAR stroke trial. Stroke (2008) 1.79
Ambient air pollution and risk for ischemic stroke and transient ischemic attack. Ann Neurol (2008) 1.77
Determining intravenous rt-PA eligibility in the Emergency Department. Neurocrit Care (2007) 1.75
Safety and tolerability of NXY-059 for acute intracerebral hemorrhage: the CHANT Trial. Stroke (2007) 1.75
The IVH score: a novel tool for estimating intraventricular hemorrhage volume: clinical and research implications. Crit Care Med (2009) 1.73
Is intra-arterial thrombolysis safe after full-dose intravenous recombinant tissue plasminogen activator for acute ischemic stroke? Stroke (2006) 1.70
The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nat Neurosci (2012) 1.70
Ultrasound-enhanced thrombolysis for acute ischemic stroke: phase I. Findings of the CLOTBUST trial. J Neuroimaging (2004) 1.69
Streamlining of prehospital stroke management: the golden hour. Lancet Neurol (2013) 1.69
The argatroban and tissue-type plasminogen activator stroke study: final results of a pilot safety study. Stroke (2012) 1.68
Identification of nonischemic stroke mimics among 411 code strokes at the University of California, San Diego, Stroke Center. J Stroke Cerebrovasc Dis (2008) 1.67
Changes in spleen size in patients with acute ischemic stroke: a pilot observational study. Int J Stroke (2012) 1.66
Problems in comprehension of informed consent in rural and peri-urban Mali, West Africa. Clin Trials (2006) 1.65
Intravenous autologous bone marrow mononuclear cells for ischemic stroke. Ann Neurol (2011) 1.64
Microvascular brain pathology and late-life motor impairment. Neurology (2013) 1.64
LOAD: a pilot study of the safety of loading of aspirin and clopidogrel in acute ischemic stroke and transient ischemic attack. J Stroke Cerebrovasc Dis (2008) 1.62
Acetaminophen for altering body temperature in acute stroke: a randomized clinical trial. Stroke (2002) 1.62
Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. Stroke (2007) 1.61
Aggressive mechanical clot disruption: a safe adjunct to thrombolytic therapy in acute stroke? Stroke (2004) 1.59
Aggressive blood pressure-lowering treatment before intravenous tissue plasminogen activator therapy in acute ischemic stroke. Arch Neurol (2008) 1.59
Accuracy of serial National Institutes of Health Stroke Scale scores to identify artery status in acute ischemic stroke. Circulation (2007) 1.58
An expedited code stroke protocol is feasible and safe. Stroke (2006) 1.57
Clinical and vascular outcome in internal carotid artery versus middle cerebral artery occlusions after intravenous tissue plasminogen activator. Stroke (2002) 1.57
Age at natural menopause and risk of ischemic stroke: the Framingham heart study. Stroke (2009) 1.57
Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. J Cereb Blood Flow Metab (2009) 1.55
Frequent early cardiac complications contribute to worse stroke outcome in atrial fibrillation. Cerebrovasc Dis (2011) 1.53
Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA). Stroke (2010) 1.53
Determining stroke's rank as a cause of death using multicause mortality data. Stroke (2012) 1.53
Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial. Ann Neurol (2009) 1.52
Emotional neglect in childhood and cerebral infarction in older age. Neurology (2012) 1.50
Yield and accuracy of urgent combined carotid/transcranial ultrasound testing in acute cerebral ischemia. Stroke (2004) 1.50
Environmental toxins and breast cancer on Long Island. II. Organochlorine compound levels in blood. Cancer Epidemiol Biomarkers Prev (2002) 1.50
Importance of early ischemic computed tomography changes using ASPECTS in NINDS rtPA Stroke Study. Stroke (2005) 1.48
Sustained benefit of a community and professional intervention to increase acute stroke therapy. Arch Intern Med (2003) 1.48
Significance of early CT signs in acute stroke. A CT scan-diffusion MRI study. Cerebrovasc Dis (2002) 1.48
Stroke Therapy Academic Industry Roundtable (STAIR) recommendations for extended window acute stroke therapy trials. Stroke (2009) 1.48
Acute Stroke Imaging Research Roadmap II. Stroke (2013) 1.47
APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study. Lancet Neurol (2011) 1.47
A prospective, multicenter pilot study to evaluate the feasibility and safety of using the CoolGard System and Icy catheter following cardiac arrest. Resuscitation (2004) 1.46
Ethnic disparities in stroke and hypertension among women: the BASIC project. Am J Hypertens (2008) 1.46
Toward more efficient clinical trials for amyotrophic lateral sclerosis. Amyotroph Lateral Scler (2010) 1.45
The impact of imbalances in baseline stroke severity on outcome in the National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study. Ann Emerg Med (2005) 1.44