Published in Neurology on January 30, 2013
A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Ann Neurol (2015) 2.16
Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology (2015) 1.53
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease. Acta Neuropathol (2013) 1.41
What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function. J Gerontol A Biol Sci Med Sci (2013) 1.05
Association of Parkinson disease risk loci with mild parkinsonian signs in older persons. JAMA Neurol (2014) 1.04
Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study. Lancet Neurol (2016) 1.02
Building a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease. Biochem Pharmacol (2014) 0.96
Brain pathology contributes to simultaneous change in physical frailty and cognition in old age. J Gerontol A Biol Sci Med Sci (2014) 0.94
Preludes to brain failure: executive dysfunction and gait disturbances. Neurol Sci (2013) 0.90
Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals. J Cereb Blood Flow Metab (2016) 0.88
The Relationship of Cerebral Vessel Pathology to Brain Microinfarcts. Brain Pathol (2016) 0.83
Microvascular disease and motoric dysfunction. Neurology (2013) 0.75
Motor Function Is Associated With Incident Disability in Older African Americans. J Gerontol A Biol Sci Med Sci (2015) 0.75
Change in motor function and adverse health outcomes in older African-Americans. Exp Gerontol (2015) 0.75
Neuropsychological Profile of "Cognitive Frailty" Subjects in MAPT Study. J Prev Alzheimers Dis (2016) 0.75
Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci (2001) 42.21
Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol (1998) 10.23
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ (2010) 7.93
Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol (2010) 5.76
Overview and findings from the rush Memory and Aging Project. Curr Alzheimer Res (2012) 4.91
Overview and findings from the religious orders study. Curr Alzheimer Res (2012) 3.46
Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr (2009) 3.44
Kidney function is related to cerebral small vessel disease. Stroke (2007) 2.77
Microinfarct pathology, dementia, and cognitive systems. Stroke (2011) 2.61
Relation of cerebral infarctions to dementia and cognitive function in older persons. Neurology (2003) 2.60
Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol (2012) 2.52
Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations. J Neurol Neurosurg Psychiatry (2010) 2.44
Association of gait and balance disorders with age-related white matter changes: the LADIS study. Neurology (2008) 2.41
Cerebral microinfarcts: the invisible lesions. Lancet Neurol (2012) 2.31
Cerebral amyloid angiopathy pathology and cognitive domains in older persons. Ann Neurol (2010) 1.96
Retinal microvascular abnormalities and subclinical magnetic resonance imaging brain infarct: a prospective study. Brain (2010) 1.73
Mild Parkinsonian signs: An overview of an emerging concept. Mov Disord (2007) 1.66
Physical frailty in older persons is associated with Alzheimer disease pathology. Neurology (2008) 1.59
The apolipoprotein E epsilon4 allele increases the odds of chronic cerebral infarction [corrected] detected at autopsy in older persons. Stroke (2005) 1.55
Hypertension, white matter hyperintensities, and concurrent impairments in mobility, cognition, and mood: the Cardiovascular Health Study. Circulation (2011) 1.51
Retinal arterial changes correlate with cerebral small-vessel disease. Neurology (2002) 1.44
Knee extensor strength, activation, and size in very elderly people following strength training. Muscle Nerve (1999) 1.41
Functional impact of white matter hyperintensities in cognitively normal elderly subjects. Arch Neurol (2010) 1.36
Combinations of motor measures more strongly predict adverse health outcomes in old age: the rush memory and aging project, a community-based cohort study. BMC Med (2011) 1.33
Impact of white matter lesions on physical functioning and fall risk in older people: a systematic review. Stroke (2011) 1.25
Sublingual microvascular changes in patients with cerebral small vessel disease. Stroke (2011) 0.84
Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement (2011) 24.02
Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol (2003) 14.87
Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials. Lancet (2004) 12.92
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet (2011) 10.07
Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology (2007) 9.27
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol (2007) 8.10
Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med (2005) 7.92
Guidelines for the primary prevention of stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke (2010) 6.93
Use of florbetapir-PET for imaging beta-amyloid pathology. JAMA (2011) 6.92
Individual differences in rates of change in cognitive abilities of older persons. Psychol Aging (2002) 6.18
Participation in cognitively stimulating activities and risk of incident Alzheimer disease. JAMA (2002) 6.18
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach. Acta Neuropathol (2011) 6.00
Charting a dynamic DNA methylation landscape of the human genome. Nature (2013) 5.80
The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort. Neuroepidemiology (2005) 5.64
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nat Genet (2010) 5.52
Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol (2004) 5.11
National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease. Alzheimers Dement (2012) 5.10
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions. Am J Pathol (2007) 5.02
The neuropathology of probable Alzheimer disease and mild cognitive impairment. Ann Neurol (2009) 4.96
Overview and findings from the rush Memory and Aging Project. Curr Alzheimer Res (2012) 4.91
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment. Science (2013) 4.71
Mild cognitive impairment can be distinguished from Alzheimer disease and normal aging for clinical trials. Arch Neurol (2004) 4.66
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease. Cell (2013) 4.45
Incidence of Alzheimer disease in a biracial urban community: relation to apolipoprotein E allele status. Arch Neurol (2003) 4.37
Predictors of ischemic stroke in the territory of a symptomatic intracranial arterial stenosis. Circulation (2006) 4.21
Upregulation of choline acetyltransferase activity in hippocampus and frontal cortex of elderly subjects with mild cognitive impairment. Ann Neurol (2002) 3.84
Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell (2013) 3.83
Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol (2011) 3.80
Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature. J Neuropathol Exp Neurol (2012) 3.77
Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol (2014) 3.75
Early and late life cognitive activity and cognitive systems in old age. J Int Neuropsychol Soc (2005) 3.68
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. Lancet Neurol (2012) 3.66
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline. J Clin Invest (2012) 3.65
Consumption of fish and n-3 fatty acids and risk of incident Alzheimer disease. Arch Neurol (2003) 3.56
Overview and findings from the religious orders study. Curr Alzheimer Res (2012) 3.46
Loneliness and risk of Alzheimer disease. Arch Gen Psychiatry (2007) 3.44
Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function. Arch Neurol (2004) 3.39
The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study. Lancet Neurol (2006) 3.38
Design of the Chicago Health and Aging Project (CHAP). J Alzheimers Dis (2003) 3.36
Dietary intake of antioxidant nutrients and the risk of incident Alzheimer disease in a biracial community study. JAMA (2002) 3.19
Decision rules guiding the clinical diagnosis of Alzheimer's disease in two community-based cohort studies compared to standard practice in a clinic-based cohort study. Neuroepidemiology (2006) 3.00
Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis. Neuron (2008) 2.99
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
National Stroke Association guidelines for the management of transient ischemic attacks. Ann Neurol (2006) 2.82
White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study. Neurobiol Aging (2005) 2.79
Much of late life cognitive decline is not due to common neurodegenerative pathologies. Ann Neurol (2013) 2.78
A review of the evidence for the use of telemedicine within stroke systems of care: a scientific statement from the American Heart Association/American Stroke Association. Stroke (2009) 2.74
Markers of increased risk of intracerebral hemorrhage after intravenous recombinant tissue plasminogen activator therapy for acute ischemic stroke in clinical practice: the Multicenter rt-PA Stroke Survey. Circulation (2002) 2.71
Contribution of Alzheimer disease to mortality in the United States. Neurology (2014) 2.67
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science (2011) 2.66
Subcortical infarcts, Alzheimer's disease pathology, and memory function in older persons. Ann Neurol (2007) 2.66
Microinfarct pathology, dementia, and cognitive systems. Stroke (2011) 2.61
Life-span cognitive activity, neuropathologic burden, and cognitive aging. Neurology (2013) 2.59
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
The neuropathology of older persons with and without dementia from community versus clinic cohorts. J Alzheimers Dis (2009) 2.54
Nigral pathology and parkinsonian signs in elders without Parkinson disease. Ann Neurol (2012) 2.52
CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology. Nat Neurosci (2013) 2.51
Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet (2010) 2.51
Olfactory identification and incidence of mild cognitive impairment in older age. Arch Gen Psychiatry (2007) 2.41
Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. Arch Neurol (2005) 2.38
Plasma microRNAs as potential biomarkers for non-small-cell lung cancer. Lab Invest (2010) 2.37
Cerebral microinfarcts: the invisible lesions. Lancet Neurol (2012) 2.31
Tests of executive function predict instrumental activities of daily living in community-dwelling older individuals. Appl Neuropsychol (2002) 2.27
Frailty is associated with incident Alzheimer's disease and cognitive decline in the elderly. Psychosom Med (2007) 2.27
Association between late-life social activity and motor decline in older adults. Arch Intern Med (2009) 2.26
Recommendations for the implementation of telemedicine within stroke systems of care: a policy statement from the American Heart Association. Stroke (2009) 2.26
Repair of Stanford type A aortic dissection with ascending aorta and hemiarch replacement combined with stent-graft elephant trunk technique by using innominate cannulation. J Thorac Cardiovasc Surg (2011) 2.21
GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology. Neurology (2012) 2.19
Substantia nigra tangles are related to gait impairment in older persons. Ann Neurol (2006) 2.17
A TREM1 variant alters the accumulation of Alzheimer-related amyloid pathology. Ann Neurol (2015) 2.16
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron (2013) 2.13
Sex differences in the clinical manifestations of Alzheimer disease pathology. Arch Gen Psychiatry (2005) 2.08