Published in J Interferon Cytokine Res on June 01, 2010
Ontogeny of early life immunity. Trends Immunol (2014) 1.35
Influence of the tryptophan-indole-IFNγ axis on human genital Chlamydia trachomatis infection: role of vaginal co-infections. Front Cell Infect Microbiol (2014) 0.95
Contribution of interleukin-12 p35 (IL-12p35) and IL-12p40 to protective immunity and pathology in mice infected with Chlamydia muridarum. Infect Immun (2013) 0.86
Mechanism of T-cell mediated protection in newborn mice against a Chlamydia infection. Microbes Infect (2013) 0.77
Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med (1989) 10.60
Respiratory-tract colonization and a distinctive pneumonia syndrome in infants infected with Chlamydia trachomatis. N Engl J Med (1977) 6.23
Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways. J Immunol (1997) 3.66
Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice. Infect Immun (1997) 3.12
Chlamydial IFN-gamma immune evasion is linked to host infection tropism. Proc Natl Acad Sci U S A (2005) 2.34
Role in vivo for gamma interferon in control of pneumonia caused by Chlamydia trachomatis in mice. Infect Immun (1988) 2.30
Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response. J Exp Med (1995) 2.17
Natural killer cell stimulatory factor (NKSF) or interleukin-12 is a key regulator of immune response and inflammation. Prog Growth Factor Res (1992) 2.05
Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFN-gamma receptor-deficient mice. J Immunol (1997) 1.76
Role of endogenous gamma interferon in host defense against Chlamydia trachomatis infections. Infect Immun (1989) 1.74
Interleukin-12 promotes gamma interferon-dependent neutrophil recruitment in the lung and improves protection against respiratory Streptococcus pneumoniae infection. Infect Immun (2007) 1.64
Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production. Infect Immun (2006) 1.63
Mapping antigenic sites on the major outer membrane protein of Chlamydia trachomatis with synthetic peptides. Infect Immun (1990) 1.58
Gamma interferon-mediated cytotoxicity related to murine Chlamydia trachomatis infection. Infect Immun (1988) 1.56
Comparison of gamma interferon-mediated antichlamydial defense mechanisms in human and mouse cells. Infect Immun (2006) 1.54
Role of neutrophils in controlling early stages of a Chlamydia trachomatis infection. Infect Immun (1996) 1.53
IFN-gamma knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection. Eur J Immunol (1999) 1.48
Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1. Am J Physiol (1997) 1.35
Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice. Cell Immunol (2004) 1.34
Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect Immun (2006) 1.27
Roles of interleukin-12 and gamma interferon in murine Chlamydia pneumoniae infection. Infect Immun (2000) 1.18
IL-12 exacerbates helminth-mediated corneal pathology by augmenting inflammatory cell recruitment and chemokine expression. J Immunol (1997) 1.16
Chlamydia trachomatis infections in neonates and young children. Semin Pediatr Infect Dis (2005) 1.15
Pulmonary assessment of children after chlamydial pneumonia of infancy. J Pediatr (1986) 1.12
Treatment of chlamydial pneumonia of infancy. Pediatrics (1979) 1.05
IL-12 contributes to allergen-induced airway inflammation in experimental asthma. J Immunol (2006) 1.01
Endogenous IFN-gamma production is induced and required for protective immunity against pulmonary chlamydial infection in neonatal mice. J Immunol (2008) 0.97
Chemokine expression in Th1 cell-induced lung injury: prominence of IFN-gamma-inducible chemokines. Am J Physiol Lung Cell Mol Physiol (2000) 0.97
Interleukin-12-induced adhesion molecule expression in murine liver. Am J Pathol (1998) 0.89
Interleukin-12 and interferon-gamma. Do they always go together? Am J Pathol (1995) 0.88
MglA regulates transcription of virulence factors necessary for Francisella tularensis intraamoebae and intramacrophage survival. Proc Natl Acad Sci U S A (2004) 4.14
Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A (2003) 4.00
Prevention of Chlamydia-induced infertility by inhibition of local caspase activity. J Infect Dis (2013) 2.79
Allelic exchange in Francisella tularensis using PCR products. FEMS Microbiol Lett (2003) 2.29
Genome-wide identification of Chlamydia trachomatis antigens associated with trachomatous trichiasis. Invest Ophthalmol Vis Sci (2012) 2.13
In vivo whole animal body imaging reveals colonization of Chlamydia muridarum to the lower genital tract at early stages of infection. Mol Imaging Biol (2014) 2.03
The Francisella tularensis pathogenicity island encodes a secretion system that is required for phagosome escape and virulence. Mol Microbiol (2009) 2.02
Activation of Raf/MEK/ERK/cPLA2 signaling pathway is essential for chlamydial acquisition of host glycerophospholipids. J Biol Chem (2003) 1.97
The chlamydial plasmid-encoded protein pgp3 is secreted into the cytosol of Chlamydia-infected cells. Infect Immun (2008) 1.97
Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection. Infect Immun (2007) 1.85
Characterization of fifty putative inclusion membrane proteins encoded in the Chlamydia trachomatis genome. Infect Immun (2008) 1.77
Contribution of polymeric immunoglobulin receptor to regulation of intestinal inflammation in dextran sulfate sodium-induced colitis. J Gastroenterol Hepatol (2006) 1.73
A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates. J Exp Med (2011) 1.70
Profiling of human antibody responses to Chlamydia trachomatis urogenital tract infection using microplates arrayed with 156 chlamydial fusion proteins. Infect Immun (2006) 1.67
Cleavage of host keratin 8 by a Chlamydia-secreted protease. Infect Immun (2004) 1.64
Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production. Infect Immun (2006) 1.63
The secreted protease factor CPAF is responsible for degrading pro-apoptotic BH3-only proteins in Chlamydia trachomatis-infected cells. J Biol Chem (2006) 1.60
Chlamydia-infected cells continue to undergo mitosis and resist induction of apoptosis. Infect Immun (2004) 1.60
Human antibody responses to a Chlamydia-secreted protease factor. Infect Immun (2004) 1.59
A genome-wide profiling of the humoral immune response to Chlamydia trachomatis infection reveals vaccine candidate antigens expressed in humans. J Immunol (2010) 1.55
Mice deficient in MyD88 Develop a Th2-dominant response and severe pathology in the upper genital tract following Chlamydia muridarum infection. J Immunol (2010) 1.49
Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cells. Infect Immun (2005) 1.48
Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection. Infect Immun (2011) 1.48
The hypothetical protein CT813 is localized in the Chlamydia trachomatis inclusion membrane and is immunogenic in women urogenitally infected with C. trachomatis. Infect Immun (2006) 1.47
CT694 and pgp3 as serological tools for monitoring trachoma programs. PLoS Negl Trop Dis (2012) 1.40
A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum. J Immunol (2009) 1.39
Intracellular interleukin-1alpha mediates interleukin-8 production induced by Chlamydia trachomatis infection via a mechanism independent of type I interleukin-1 receptor. Infect Immun (2007) 1.37
Cleavage-dependent activation of a chlamydia-secreted protease. Mol Microbiol (2004) 1.37
Structural basis for activation and inhibition of the secreted chlamydia protease CPAF. Cell Host Microbe (2008) 1.36
Chlamydia trachomatis infection inhibits both Bax and Bak activation induced by staurosporine. Infect Immun (2004) 1.36
Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. J Immunol (2008) 1.34
Chlamydia trachomatis pulmonary infection induces greater inflammatory pathology in immunoglobulin A deficient mice. Cell Immunol (2004) 1.34
Chlamydia vaccine candidates and tools for chlamydial antigen discovery. Expert Rev Vaccines (2009) 1.34
Characterization of Chlamydia trachomatis plasmid-encoded open reading frames. J Bacteriol (2013) 1.31
Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection. Vaccine (2007) 1.28
Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect Immun (2006) 1.27
Intranasal vaccination with a defined attenuated Francisella novicida strain induces gamma interferon-dependent antibody-mediated protection against tularemia. Infect Immun (2006) 1.27
Production of a proteolytically active protein, chlamydial protease/proteasome-like activity factor, by five different Chlamydia species. Infect Immun (2005) 1.26
Intramolecular dimerization is required for the chlamydia-secreted protease CPAF to degrade host transcriptional factors. Infect Immun (2004) 1.25
Inhibition of host cell cytokinesis by Chlamydia trachomatis infection. J Infect (2003) 1.24
Influenza A (H3N2) outbreak, Nepal. Emerg Infect Dis (2005) 1.23
Targeted inactivation of francisella tularensis genes by group II introns. Appl Environ Microbiol (2008) 1.22
Next-generation ion torrent sequencing of drug resistance mutations in Mycobacterium tuberculosis strains. J Clin Microbiol (2012) 1.22
Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4. Proc Natl Acad Sci U S A (2008) 1.21
Genome-wide identification of Chlamydia trachomatis antigens associated with tubal factor infertility. Fertil Steril (2011) 1.21
Inhibition of proteolytic activity of a chlamydial proteasome/protease-like activity factor by antibodies from humans infected with Chlamydia trachomatis. Infect Immun (2005) 1.21
ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis. J Immunol (2005) 1.20
Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection. Antimicrob Agents Chemother (2004) 1.20
Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift. Proc Natl Acad Sci U S A (2011) 1.18
Multi-genome identification and characterization of chlamydiae-specific type III secretion substrates: the Inc proteins. BMC Genomics (2011) 1.18
Characterization of Pgp3, a Chlamydia trachomatis plasmid-encoded immunodominant antigen. J Bacteriol (2010) 1.18
The protective efficacy of chlamydial protease-like activity factor vaccination is dependent upon CD4+ T cells. Cell Immunol (2006) 1.16
Delivery of IL-12 intranasally leads to reduced IL-12-mediated toxicity. Int Immunopharmacol (2003) 1.16
NF-kappa B activation is not required for Chlamydia trachomatis inhibition of host epithelial cell apoptosis. J Immunol (2005) 1.14
Biosensor recognition elements. Curr Issues Mol Biol (2008) 1.13
Oral live vaccine strain-induced protective immunity against pulmonary Francisella tularensis challenge is mediated by CD4+ T cells and antibodies, including immunoglobulin A. Clin Vaccine Immunol (2009) 1.12
Production of tumor necrosis factor-alpha, interleukin 1-beta, interleukin 2, and interleukin 6 by rat leukocyte subpopulations after exposure to substance P. Neuropeptides (2003) 1.12
Chlamydia trachomatis antigens recognized in women with tubal factor infertility, normal fertility, and acute infection. Obstet Gynecol (2012) 1.10
Antibodies from women urogenitally infected with C. trachomatis predominantly recognized the plasmid protein pgp3 in a conformation-dependent manner. BMC Microbiol (2008) 1.10
Reduced live organism recovery and lack of hydrosalpinx in mice infected with plasmid-free Chlamydia muridarum. Infect Immun (2013) 1.10
Association of tubal factor infertility with elevated antibodies to Chlamydia trachomatis caseinolytic protease P. Am J Obstet Gynecol (2010) 1.09
Secretion of the chlamydial virulence factor CPAF requires the Sec-dependent pathway. Microbiology (2010) 1.08
Chlamydia trachomatis secretion of hypothetical protein CT622 into host cell cytoplasm via a secretion pathway that can be inhibited by the type III secretion system inhibitor compound 1. Microbiology (2011) 1.07
Chlamydia pneumoniae secretion of a protease-like activity factor for degrading host cell transcription factors required for [correction of factors is required for] major histocompatibility complex antigen expression. Infect Immun (2002) 1.06
Oviduct infection and hydrosalpinx in DBA1/j mice is induced by intracervical but not intravaginal inoculation with Chlamydia muridarum. PLoS One (2013) 1.06
Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium. J Biol Chem (2006) 1.06
A limited role for antibody in protective immunity induced by rCPAF and CpG vaccination against primary genital Chlamydia muridarum challenge. FEMS Immunol Med Microbiol (2009) 1.05
Identification of Chlamydia trachomatis outer membrane complex proteins by differential proteomics. J Bacteriol (2010) 1.05
OxLDL stimulates cell proliferation through a general induction of cell cycle proteins. Am J Physiol Heart Circ Physiol (2003) 1.05