Published in Am J Kidney Dis on March 01, 2010
Renal Fanconi syndrome secondary to deferasirox: where there is smoke there is fire. J Pediatr Hematol Oncol (2010) 0.94
A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. PLoS One (2015) 0.75
Fanconi syndrome due to deferasirox. Am J Kidney Dis (2009) 1.61
Identification of an intestinal heme transporter. Cell (2005) 3.05
The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment. Chem Biol (2007) 2.05
Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica (2009) 1.51
Release of redox-active iron by muscle crush trauma: no liberation into the circulation. Shock (2010) 1.44
The crucial role of metal ions in neurodegeneration: the basis for a promising therapeutic strategy. Br J Pharmacol (2005) 1.32
Iron chelators can protect against oxidative stress through ferryl heme reduction. Free Radic Biol Med (2007) 1.31
Metals ions and neurodegeneration. Biometals (2007) 1.24
Design of clinically useful iron(III)-selective chelators. Med Res Rev (2002) 1.21
Tyrosine as a redox-active center in electron transfer to ferryl heme in globins. Free Radic Biol Med (2007) 1.19
Nature of non-transferrin-bound iron: studies on iron citrate complexes and thalassemic sera. J Biol Inorg Chem (2007) 1.18
Results of an international round robin for the quantification of serum non-transferrin-bound iron: Need for defining standardization and a clinically relevant isoform. Anal Biochem (2005) 1.16
Design, synthesis, physicochemical properties, and evaluation of novel iron chelators with fluorescent sensors. J Med Chem (2004) 1.14
Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with beta-thalassaemia major: application of SQUID biomagnetic liver susceptometry. Br J Haematol (2003) 1.13
Feruloyl-CoA 6'-Hydroxylase1-dependent coumarins mediate iron acquisition from alkaline substrates in Arabidopsis. Plant Physiol (2013) 1.10
Iron(III) citrate speciation in aqueous solution. Dalton Trans (2009) 1.09
Current status of the measurement of blood hepcidin levels in chronic kidney disease. Clin J Am Soc Nephrol (2010) 1.08
Design of iron chelators with therapeutic application. Dalton Trans (2012) 1.06
Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1). Br J Nutr (2008) 1.04
Aceruloplasminemia: new clinical, pathophysiological and therapeutic insights. J Hepatol (2002) 1.04
Serum iron curves can be used to estimate dietary iron bioavailability in humans. J Nutr (2006) 1.03
Influence of non-enzymatic post-translation modifications on the ability of human serum albumin to bind iron. Implications for non-transferrin-bound iron speciation. Biochim Biophys Acta (2009) 1.01
Novel diterpenoid acetylcholinesterase inhibitors from Salvia miltiorhiza. Planta Med (2004) 1.00
Quantification of hepcidin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom (2009) 0.98
Tripodal tris(hydroxypyridinone) ligands for immunoconjugate PET imaging with (89)Zr(4+): comparison with desferrioxamine-B. Dalton Trans (2015) 0.97
Genetic epidemiology of induced CYP3A4 activity. Pharmacogenet Genomics (2011) 0.95
Quantitation of hepcidin in serum using ultra-high-pressure liquid chromatography and a linear ion trap mass spectrometer. Rapid Commun Mass Spectrom (2010) 0.94
Quantitation of hepcidin in human urine by liquid chromatography-mass spectrometry. Anal Biochem (2008) 0.93
Identification of a new hexadentate iron chelator capable of restricting the intramacrophagic growth of Mycobacterium avium. Microbes Infect (2010) 0.93
Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone) ligands. Chem Commun (Camb) (2011) 0.93
Iron binding dendrimers: a novel approach for the treatment of haemochromatosis. J Med Chem (2006) 0.93
Iron requirements based upon iron absorption tests are poorly predicted by haematological indices in patients with inactive inflammatory bowel disease. Br J Nutr (2011) 0.93
Common presence of non-transferrin-bound iron among patients with type 2 diabetes. Diabetes Care (2006) 0.92
Iron mobilization from transferrin by therapeutic iron chelating agents. Biochim Biophys Acta (2011) 0.90
Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone. Transl Res (2010) 0.90
Neuroprotective actions of deferiprone in cultured cortical neurones and SHSY-5Y cells. J Neurochem (2008) 0.89
Targeting the lysosome: fluorescent iron(III) chelators to selectively monitor endosomal/lysosomal labile iron pools. J Med Chem (2008) 0.88
Chelation and determination of labile iron in primary hepatocytes by pyridinone fluorescent probes. Biochem J (2006) 0.87
Basic 3-hydroxypyridin-4-ones: potential antimalarial agents. Eur J Med Chem (2007) 0.86
Relevant activities of extracts and constituents of animals used in traditional Chinese medicine for central nervous system effects associated with Alzheimer's disease. J Pharm Pharmacol (2006) 0.86
Design, synthesis, and evaluation of novel 2-substituted 3-hydroxypyridin-4-ones: structure-activity investigation of metalloenzyme inhibition by iron chelators. J Med Chem (2002) 0.86
Fenton chemistry and iron chelation under physiologically relevant conditions: Electrochemistry and kinetics. Chem Res Toxicol (2006) 0.84
Induction of hypoxia inducible factor (HIF-1α) in rat kidneys by iron chelation with the hydroxypyridinone, CP94. Biochim Biophys Acta (2011) 0.83
Incorporation of 2,3-diaminopropionic acid into linear cationic amphipathic peptides produces pH-sensitive vectors. Chembiochem (2010) 0.83
Amides from Piper nigrum L. with dissimilar effects on melanocyte proliferation in-vitro. J Pharm Pharmacol (2007) 0.82
Synthesis of double-clickable functionalised graphene oxide for biological applications. Chem Commun (Camb) (2015) 0.82
Synthesis and antiviral evaluation of 3-hydroxy-2-methylpyridin-4-one dideoxynucleoside derivatives. Bioorg Med Chem Lett (2003) 0.82
Non-transferrin-bound iron (NTBI) uptake by T lymphocytes: evidence for the selective acquisition of oligomeric ferric citrate species. PLoS One (2013) 0.81
Fluorescent 3-hydroxy-4-pyridinone hexadentate iron chelators: intracellular distribution and the relevance to antimycobacterial properties. J Biol Inorg Chem (2010) 0.81
The fenton activity of iron(III) in the presence of deferiprone. J Pharm Sci (2008) 0.80
Post-prandial iron absorption in humans: comparison between HFE genotypes and iron deficiency anaemia. Clin Nutr (2008) 0.80
Structural analysis of cytochrome P450 105N1 involved in the biosynthesis of the zincophore, coelibactin. Int J Mol Sci (2012) 0.80
The labile iron pool of hepatocytes in chronic and acute iron overload and chelator-induced iron deprivation. J Hepatol (2002) 0.80
Design, synthesis and properties of novel iron(III)-specific fluorescent probes. J Pharm Pharmacol (2004) 0.80
Conjugation to 4-aminoquinoline improves the anti-trypanosomal activity of Deferiprone-type iron chelators. Bioorg Med Chem (2012) 0.79
Novel iron-specific fluorescent probes. Bioorg Med Chem Lett (2005) 0.79
In vitro inhibition of bacterial growth by iron chelators. FEMS Microbiol Lett (2010) 0.79
Iron mobilization, cytoprotection, and inhibition of cell proliferation in normal and transformed rat hepatocyte cultures by the hydroxypyridinone CP411, compared to CP20: a biological and physicochemical study. Biochem Pharmacol (2004) 0.79
Functional characterization of fluorescent hepcidin. Bioconjug Chem (2013) 0.78
Chelator-facilitated removal of iron from transferrin: relevance to combined chelation therapy. Biochem J (2008) 0.78
Ga(III) complexes--the effect of metal coordination on potential systemic absorption after topical exposure. Toxicol Lett (2011) 0.78
Monitoring intracellular labile iron pools: A novel fluorescent iron(III) sensor as a potential non-invasive diagnosis tool. J Pharm Sci (2009) 0.78
Determination of the pKa value of the hydroxyl group in the alpha-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems. Biometals (2009) 0.78
Synthesis and iron(III)-chelating properties of novel 3-hydroxypyridin-4-one hexadentate ligand-containing copolymers. Biomacromolecules (2008) 0.77
Synthesis and in-vitro antimicrobial evaluation of a high-affinity iron chelator in combination with chloramphenicol. J Pharm Pharmacol (2012) 0.77
Synthesis, physical-chemical characterisation and biological evaluation of novel 2-amido-3-hydroxypyridin-4(1H)-ones: Iron chelators with the potential for treating Alzheimer's disease. Bioorg Med Chem (2010) 0.77
Oral iron chelators--development and application. Best Pract Res Clin Haematol (2002) 0.77
High affinity iron(III) scavenging by a novel hexadentate 3-hydroxypyridin-4-one-based dendrimer: synthesis and characterization. Bioorg Med Chem Lett (2005) 0.77
Design and synthesis of fluorinated iron chelators for metabolic study and brain uptake. J Med Chem (2012) 0.76
Design, synthesis and biological evaluation of peptide derivatives of L-dopa as anti-parkinsonian agents. Bioorg Med Chem Lett (2013) 0.76
Iron chelator chemistry. Adv Exp Med Biol (2002) 0.76
Amido-3-hydroxypyridin-4-ones as iron(III) ligands. Chemistry (2010) 0.76
Mode of iron(III) chelation by hexadentate hydroxypyridinones. Chem Commun (Camb) (2015) 0.76
Effects of piperine analogues on stimulation of melanocyte proliferation and melanocyte differentiation. Bioorg Med Chem (2004) 0.76
Characterisation of a novel oral iron chelator: 1-(N-Acetyl-6-Aminohexyl)-3-Hydroxy-2-Methylpyridin-4-one. J Pharm Pharmacol (2015) 0.76
Glucosylated deferiprone and its brain uptake: implications for developing glucosylated hydroxypyridinone analogues intended to cross the blood-brain barrier. J Med Chem (2010) 0.75
Design of clinically useful macromolecular iron chelators. J Pharm Pharmacol (2011) 0.75
Determination of the labile iron pool of human lymphocytes using the fluorescent probe, CP655. Anal Chem Insights (2007) 0.75
In vitro antimicrobial activity of hydroxypyridinone hexadentate-based dendrimeric chelators alone and in combination with norfloxacin. FEMS Microbiol Lett (2014) 0.75
pH indicator titration: a novel fast pKa determination method. J Pharm Sci (2007) 0.75
Synthesis and physicochemical assessment of novel 2-substituted 3-hydroxypyridin-4-ones, novel iron chelators. J Pharm Pharmacol (2002) 0.75
Design and synthesis of hydroxypyridinone-L-phenylalanine conjugates as potential tyrosinase inhibitors. J Agric Food Chem (2013) 0.75
3-Hydroxy-2-(5-hydroxypentyl)-4H-chromen-4-one: a bidentate or tridentate iron(III) ligand? J Med Chem (2006) 0.75
Structural characterization of chelator-terminated dendrimers and their synthetic intermediates by mass spectrometry. J Mass Spectrom (2005) 0.75
Synthesis and characterizations of pyridazine-based iron chelators. Dalton Trans (2014) 0.75
The binding of aluminum to mugineic acid and related compounds as studied by potentiometric titration. Biometals (2011) 0.75
Synthesis and antiviral evaluation of cyclic and acyclic 2-methyl-3-hydroxy-4-pyridinone nucleoside derivatives. J Med Chem (2006) 0.75
MALDI mass spectrometric determination of dendritic iron chelation stoichiometries and conditional affinity constants. J Mass Spectrom (2008) 0.75
Prediction of 3-hydroxypyridin-4-one (HPO) log K1 values for Fe(III). Dalton Trans (2012) 0.75
A novel fluorescence method for determination of pFe3+. Analyst (2012) 0.75
pFe(3+) determination of multidentate ligands by a fluorescence assay. Analyst (2015) 0.75
Prediction of 3-hydroxypyridin-4-one (HPO) hydroxyl pKa values. Dalton Trans (2012) 0.75
Design, synthesis, and antimicrobial evaluation of hexadentate hydroxypyridinones with high iron(III) affinity. Chem Biol Drug Des (2014) 0.75
Design, synthesis and biological evaluation of L-dopa amide derivatives as potential prodrugs for the treatment of Parkinson's disease. Eur J Med Chem (2010) 0.75
The selective quantification of iron by hexadentate fluorescent probes. Bioorg Med Chem (2009) 0.75
Synthesis, iron(III)-binding affinity and in vitro evaluation of 3-hydroxypyridin-4-one hexadentate ligands as potential antimicrobial agents. Bioorg Med Chem Lett (2011) 0.75
A manganese superoxide dismutase mimic based on cis,cis-1,3,5-triaminocyclohexane. Dalton Trans (2003) 0.75
UV irradiation affects melanocyte stimulatory activity and protein binding of piperine. Photochem Photobiol (2007) 0.75