A molecular dissociation between cued and contextual appetitive learning.

PubWeight™: 0.81‹?›

🔗 View Article (PMC 2832921)

Published in Learn Mem on February 26, 2010

Authors

Mazen A Kheirbek1, Jeff A Beeler, Wanhao Chi, Yoshihiro Ishikawa, Xiaoxi Zhuang

Author Affiliations

1: Committee on Neurobiology, The University of Chicago, Chicago, Illinois 60637, USA. mk3156@columbia.edu

Articles cited by this

A neural substrate of prediction and reward. Science (1997) 31.30

Emotion circuits in the brain. Annu Rev Neurosci (2000) 24.39

Predictive reward signal of dopamine neurons. J Neurophysiol (1998) 15.02

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning. Behav Neurosci (1992) 11.73

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell (2005) 5.60

Associative learning mediates dynamic shifts in dopamine signaling in the nucleus accumbens. Nat Neurosci (2007) 4.97

Conditioned place preference: what does it add to our preclinical understanding of drug reward? Psychopharmacology (Berl) (2000) 4.95

Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory. Cell (1997) 4.83

The control of firing pattern in nigral dopamine neurons: burst firing. J Neurosci (1984) 4.52

Temporally precise in vivo control of intracellular signalling. Nature (2009) 4.14

A cellular mechanism of reward-related learning. Nature (2001) 4.09

Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol (2001) 3.21

Convergence and segregation of ventral striatal inputs and outputs. Ann N Y Acad Sci (1999) 3.18

The role of the nucleus accumbens in instrumental conditioning: Evidence of a functional dissociation between accumbens core and shell. J Neurosci (2001) 3.15

Intra-accumbens amphetamine increases the conditioned incentive salience of sucrose reward: enhancement of reward "wanting" without enhanced "liking" or response reinforcement. J Neurosci (2000) 3.06

The control of firing pattern in nigral dopamine neurons: single spike firing. J Neurosci (1984) 2.99

Contextual fear, gestalt memories, and the hippocampus. Behav Brain Res (2000) 2.95

Dissociation in effects of lesions of the nucleus accumbens core and shell on appetitive pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by D-amphetamine. J Neurosci (1999) 2.81

Dopamine-dependent plasticity of corticostriatal synapses. Neural Netw (2002) 2.65

Burst firing in midbrain dopaminergic neurons. Brain Res Brain Res Rev (1997) 2.59

Anatomical and affinity state comparisons between dopamine D1 and D2 receptors in the rat central nervous system. Neuroscience (1989) 2.29

General and outcome-specific forms of Pavlovian-instrumental transfer: the effect of shifts in motivational state and inactivation of the ventral tegmental area. Eur J Neurosci (2007) 1.89

Limbic and cortical information processing in the nucleus accumbens. Trends Neurosci (2008) 1.73

Prolonged and extrasynaptic excitatory action of dopamine mediated by D1 receptors in the rat striatum in vivo. J Neurosci (1997) 1.59

Hippocampal and prefrontal cortical inputs monosynaptically converge with individual projection neurons of the nucleus accumbens. J Comp Neurol (2002) 1.57

Individual nucleus accumbens-projection neurons receive both basolateral amygdala and ventral subicular afferents in rats. Neuroscience (2003) 1.52

Hippocampal place cells, context, and episodic memory. Hippocampus (2006) 1.51

Configural association theory and the hippocampal formation: an appraisal and reconfiguration. Hippocampus (1995) 1.50

SKF83959 selectively regulates phosphatidylinositol-linked D1 dopamine receptors in rat brain. J Neurochem (2003) 1.46

Functional interaction between the hippocampus and nucleus accumbens shell is necessary for the acquisition of appetitive spatial context conditioning. J Neurosci (2008) 1.40

Why calcium-stimulated adenylyl cyclases? Physiology (Bethesda) (2004) 1.39

Regulation of adenylyl cyclase by protein kinase A. J Biol Chem (1995) 1.36

The phasic reward signal of primate dopamine neurons. Adv Pharmacol (1998) 1.33

Motor dysfunction in type 5 adenylyl cyclase-null mice. J Biol Chem (2003) 1.32

Instrumental learning in hyperdopaminergic mice. Neurobiol Learn Mem (2006) 1.22

Impaired bidirectional synaptic plasticity and procedural memory formation in striatum-specific cAMP response element-binding protein-deficient mice. J Neurosci (2006) 1.18

Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. J Neurosci (2009) 1.11

Selective excitotoxic lesions of the hippocampus and basolateral amygdala have dissociable effects on appetitive cue and place conditioning based on path integration in a novel Y-maze procedure. Eur J Neurosci (2006) 1.06

Pavlovian influences on goal-directed behavior in mice: the role of cue-reinforcer relations. Learn Mem (2008) 1.05

Opposing roles of D1 and D2 receptors in appetitive conditioning. J Neurosci (2003) 1.04

Neuropsychopharmacology of drug seeking: Insights from studies with second-order schedules of drug reinforcement. Eur J Pharmacol (2005) 1.04

A role for calmodulin-stimulated adenylyl cyclases in cocaine sensitization. J Neurosci (2009) 1.02

The hippocampus and appetitive Pavlovian conditioning: effects of excitotoxic hippocampal lesions on conditioned locomotor activity and autoshaping. Hippocampus (2005) 1.02

Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology (2007) 1.00

SCH 23390 blocks drug-conditioned place-preference and place-aversion: anhedonia (lack of reward) or apathy (lack of motivation) after dopamine-receptor blockade? Psychopharmacology (Berl) (1989) 0.96

A cAMP pathway underlying reward prediction in associative learning. J Neurosci (2008) 0.95

Dopamine, neuroleptics and reinforced behavior. Neurosci Biobehav Rev (1989) 0.91

Dopamine D1A receptor regulation of phospholipase C isoform. J Biol Chem (1996) 0.90

Ca2+-sensitive adenylyl cyclases, key integrators of cellular signalling. Life Sci (1998) 0.90

Loss of cocaine locomotor response in Pitx3-deficient mice lacking a nigrostriatal pathway. Neuropsychopharmacology (2008) 0.88

Nucleus accumbens PKA inhibition blocks acquisition but enhances expression of amphetamine-produced conditioned activity in rats. Psychopharmacology (Berl) (2006) 0.85

Articles by these authors

Retracted Expression of concern: Decline in NRF2-regulated antioxidants in chronic obstructive pulmonary disease lungs due to loss of its positive regulator, DJ-1. Am J Respir Crit Care Med (2008) 3.93

Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature (2002) 3.92

Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. J Clin Invest (2009) 3.17

Type 5 adenylyl cyclase disruption increases longevity and protects against stress. Cell (2007) 2.96

Dopamine neurons mediate a fast excitatory signal via their glutamatergic synapses. J Neurosci (2004) 2.45

Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards. J Neurosci (2003) 2.00

Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. J Biol Chem (2005) 1.75

Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system. PLoS Biol (2007) 1.72

Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun (2004) 1.69

A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Arch Gen Psychiatry (2009) 1.69

Disruption of type 5 adenylyl cyclase gene preserves cardiac function against pressure overload. Proc Natl Acad Sci U S A (2003) 1.64

Mice with chronically elevated dopamine exhibit enhanced motivation, but not learning, for a food reward. Neuropsychopharmacology (2005) 1.60

Cardiac-specific overexpression of caveolin-3 induces endogenous cardiac protection by mimicking ischemic preconditioning. Circulation (2008) 1.56

Epac increases melanoma cell migration by a heparan sulfate-related mechanism. Am J Physiol Cell Physiol (2009) 1.54

DNA microarray profiling identified a new role of growth hormone in vascular remodeling of rat ductus arteriosus. J Physiol Sci (2011) 1.49

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease. Lancet Neurol (2013) 1.48

Caveolin gene transfer improves glucose metabolism in diabetic mice. Am J Physiol Cell Physiol (2009) 1.45

Transgenic mouse models of dopamine deficiency. Ann Neurol (2003) 1.45

Atrial chamber-specific expression of sarcolipin is regulated during development and hypertrophic remodeling. J Biol Chem (2003) 1.44

Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice. J Neurosci (2008) 1.43

Disruption of type 5 adenylyl cyclase enhances desensitization of cyclic adenosine monophosphate signal and increases Akt signal with chronic catecholamine stress. Circulation (2007) 1.37

Dopamine scales performance in the absence of new learning. Neuron (2006) 1.35

Motor dysfunction in type 5 adenylyl cyclase-null mice. J Biol Chem (2003) 1.32

Direct inhibition of type 5 adenylyl cyclase prevents myocardial apoptosis without functional deterioration. J Biol Chem (2004) 1.31

Sequential super-stereotypy of an instinctive fixed action pattern in hyper-dopaminergic mutant mice: a model of obsessive compulsive disorder and Tourette's. BMC Biol (2005) 1.30

Chronic activation of the prostaglandin receptor EP4 promotes hyaluronan-mediated neointimal formation in the ductus arteriosus. J Clin Invest (2006) 1.29

Caveolin-3 expression and caveolae are required for isoflurane-induced cardiac protection from hypoxia and ischemia/reperfusion injury. J Mol Cell Cardiol (2007) 1.28

Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system. Biol Psychiatry (2003) 1.28

Type 5 adenylyl cyclase disruption alters not only sympathetic but also parasympathetic and calcium-mediated cardiac regulation. Circ Res (2003) 1.25

Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. Am J Physiol Heart Circ Physiol (2007) 1.23

Instrumental learning in hyperdopaminergic mice. Neurobiol Learn Mem (2006) 1.22

Serotonin transporter transgenic (SERTcre) mouse line reveals developmental targets of serotonin specific reuptake inhibitors (SSRIs). Neuropharmacology (2008) 1.18

Tonic dopamine modulates exploitation of reward learning. Front Behav Neurosci (2010) 1.17

Adenylyl cyclase type 5 protein expression during cardiac development and stress. Am J Physiol Heart Circ Physiol (2009) 1.16

Dopamine-dependent motor learning: insight into levodopa's long-duration response. Ann Neurol (2010) 1.12

Adenylyl cyclase type 5 contributes to corticostriatal plasticity and striatum-dependent learning. J Neurosci (2009) 1.11

Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression. BMC Neurosci (2007) 1.09

The prostanoid EP4 receptor and its signaling pathway. Pharmacol Rev (2013) 1.08

Congenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon. Mol Cell Biol (2005) 1.08

Insulin resistance in skeletal muscles of caveolin-3-null mice. Proc Natl Acad Sci U S A (2004) 1.07

Multiple transcripts of Ca2+ channel alpha1-subunits and a novel spliced variant of the alpha1C-subunit in rat ductus arteriosus. Am J Physiol Heart Circ Physiol (2005) 1.07

Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration. Am J Physiol Heart Circ Physiol (2008) 1.06

Prolyl 3-hydroxylase 1 null mice display abnormalities in fibrillar collagen-rich tissues such as tendons, skin, and bones. J Biol Chem (2010) 1.06

Impaired Ca2+ store functions in skeletal and cardiac muscle cells from sarcalumenin-deficient mice. J Biol Chem (2004) 1.05

Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice. Hum Mol Genet (2007) 1.05

Low amplitude entrainment of mice and the impact of circadian phase on behavior tests. Physiol Behav (2006) 1.04

Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain. J Clin Invest (2013) 1.02

Differential roles of Epac in regulating cell death in neuronal and myocardial cells. J Biol Chem (2010) 1.02

Taste uncoupled from nutrition fails to sustain the reinforcing properties of food. Eur J Neurosci (2012) 1.02

Sucrose-predictive cues evoke greater phasic dopamine release than saccharin-predictive cues. Synapse (2011) 1.01

Putting desire on a budget: dopamine and energy expenditure, reconciling reward and resources. Front Integr Neurosci (2012) 1.00

Chronic blockade or constitutive deletion of the serotonin transporter reduces operant responding for food reward. Neuropsychopharmacology (2007) 1.00

Translocation of caveolin regulates stretch-induced ERK activity in vascular smooth muscle cells. Am J Physiol Heart Circ Physiol (2004) 0.99

Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. Circulation (2013) 0.99

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43). J Biol Chem (2009) 0.98

T-type Ca2+ channels promote oxygenation-induced closure of the rat ductus arteriosus not only by vasoconstriction but also by neointima formation. J Biol Chem (2009) 0.98

Mice lacking hypertension candidate gene ATP2B1 in vascular smooth muscle cells show significant blood pressure elevation. Hypertension (2012) 0.98

Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation. J Biol Chem (2011) 0.97

Nicotinic acetylcholine receptor alpha 7 regulates cAMP signal within lipid rafts. Am J Physiol Cell Physiol (2003) 0.95

A cAMP pathway underlying reward prediction in associative learning. J Neurosci (2008) 0.95

A case of giant coronary artery aneurysm and literature review. J Cardiol (2008) 0.94

Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J Biol Chem (2013) 0.94

Mechanical stress-dependent transcriptional regulation of sarcolipin gene in the rodent atrium. Biochem Biophys Res Commun (2005) 0.94

The antioxidant Trolox helps recovery from the familial Parkinson's disease-specific mitochondrial deficits caused by PINK1- and DJ-1-deficiency in dopaminergic neuronal cells. Mitochondrion (2011) 0.94

Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase. Am J Physiol Heart Circ Physiol (2012) 0.93

Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A. J Biol Chem (2008) 0.93

Inhibition of EP4 signaling attenuates aortic aneurysm formation. PLoS One (2012) 0.93

Altered corticostriatal neurotransmission and modulation in dopamine transporter knock-down mice. J Neurophysiol (2007) 0.93

Role of the calcium modulated cyclases in the development of the retinal projections. Eur J Neurosci (2006) 0.92

Sarcalumenin alleviates stress-induced cardiac dysfunction by improving Ca2+ handling of the sarcoplasmic reticulum. Cardiovasc Res (2007) 0.91

Caveolin-3 inhibits growth signal in cardiac myoblasts in a Ca2+-dependent manner. J Cell Mol Med (2006) 0.90

Dopamine induces apoptosis in young, but not in neonatal, neurons via Ca2+-dependent signal. Am J Physiol Cell Physiol (2007) 0.90

Sucrose exposure in early life alters adult motivation and weight gain. PLoS One (2008) 0.89

Exendin-4 ameliorates cardiac ischemia/reperfusion injury via caveolae and caveolins-3. Cardiovasc Diabetol (2014) 0.89

Oxidized galectin-1 stimulates macrophages to promote axonal regeneration in peripheral nerves after axotomy. J Neurosci (2004) 0.89

Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses. J Clin Invest (2014) 0.89

A role for dopamine-mediated learning in the pathophysiology and treatment of Parkinson's disease. Cell Rep (2012) 0.88

Loss of cocaine locomotor response in Pitx3-deficient mice lacking a nigrostriatal pathway. Neuropsychopharmacology (2008) 0.88

Posttranslational modifications in type I collagen from different tissues extracted from wild type and prolyl 3-hydroxylase 1 null mice. J Biol Chem (2013) 0.88

Serial alterations of beta-adrenergic signaling in dilated cardiomyopathic hamsters: possible role of myocardial oxidative stress. Circ J (2004) 0.88

Apoptosis in heart failure. -The role of the β-adrenergic receptor-mediated signaling pathway and p53-mediated signaling pathway in the apoptosis of cardiomyocytes-. Circ J (2011) 0.88

Effect of ascorbic acid on reactive oxygen species production in chemotherapy and hyperthermia in prostate cancer cells. J Physiol Sci (2012) 0.87

Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia. J Neurosci (2014) 0.87

Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload. Am J Physiol Heart Circ Physiol (2010) 0.87

PINK1 deficiency attenuates astrocyte proliferation through mitochondrial dysfunction, reduced AKT and increased p38 MAPK activation, and downregulation of EGFR. Glia (2013) 0.86

Diabetes is not a potent inducer of neuronal cell death in mouse sensory ganglia, but it enhances neurite regeneration in vitro. Life Sci (2002) 0.86

Post-transcriptional downregulation of sarcolipin mRNA by triiodothyronine in the atrial myocardium. FEBS Lett (2006) 0.86

Drug therapy aimed at adenylyl cyclase to regulate cyclic nucleotide signaling. Endocr Metab Immune Disord Drug Targets (2006) 0.86

Brain-derived neurotrophic factor enhances neurite regeneration from retinal ganglion cells in aged human retina in vitro. Exp Eye Res (2002) 0.85

Dopaminergic enhancement of local food-seeking is under global homeostatic control. Eur J Neurosci (2011) 0.85

Accessory proteins for heterotrimeric G-protein: Implication in the cardiovascular system. Pathophysiology (2009) 0.85

Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator. J Biol Chem (2011) 0.85

Adenylyl cyclase type 5 disruption prolongs longevity and protects the heart against stress. Circ J (2008) 0.84