Elazer R Edelman

Author PubWeight™ 130.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Efficacy of a device to narrow the coronary sinus in refractory angina. N Engl J Med 2015 5.36
2 Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol 2007 4.62
3 Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings. Circulation 2011 3.16
4 Kruppel-like factor 4 regulates endothelial inflammation. J Biol Chem 2007 3.06
5 Luminal flow patterns dictate arterial drug deposition in stent-based delivery. J Control Release 2008 1.90
6 Tissue engineering therapy for cardiovascular disease. Circ Res 2003 1.87
7 Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study. Circulation 2008 1.74
8 Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice. Circulation 2003 1.72
9 Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor. Circulation 2012 1.70
10 Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Circ Res 2008 1.64
11 Stromal endothelial cells directly influence cancer progression. Sci Transl Med 2011 1.46
12 In vivo and in vitro tracking of erosion in biodegradable materials using non-invasive fluorescence imaging. Nat Mater 2011 1.46
13 Drug-eluting stents in preclinical studies: recommended evaluation from a consensus group. Circulation 2002 1.45
14 Ultrasound-guided percutaneous delivery of tissue-engineered endothelial cells to the adventitia of stented arteries controls the response to vascular injury in a porcine model. J Vasc Surg 2012 1.42
15 Vascular neointimal formation and signaling pathway activation in response to stent injury in insulin-resistant and diabetic animals. Circ Res 2005 1.32
16 Specific binding to intracellular proteins determines arterial transport properties for rapamycin and paclitaxel. Proc Natl Acad Sci U S A 2004 1.32
17 Aldehyde-amine chemistry enables modulated biosealants with tissue-specific adhesion. Adv Mater 2009 1.31
18 Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution. J Control Release 2007 1.29
19 Enhanced T-helper-1 lymphocyte activation patterns in acute coronary syndromes. J Am Coll Cardiol 2005 1.27
20 Strut position, blood flow, and drug deposition: implications for single and overlapping drug-eluting stents. Circulation 2005 1.26
21 Natural history of experimental coronary atherosclerosis and vascular remodeling in relation to endothelial shear stress: a serial, in vivo intravascular ultrasound study. Circulation 2010 1.19
22 Vascular bed origin dictates flow pattern regulation of endothelial adhesion molecule expression. Am J Physiol Heart Circ Physiol 2007 1.18
23 Characterization of star adhesive sealants based on PEG/dextran hydrogels. Macromol Biosci 2009 1.18
24 Luminal flow amplifies stent-based drug deposition in arterial bifurcations. PLoS One 2009 1.17
25 Perivascular endothelial implants inhibit intimal hyperplasia in a model of arteriovenous fistulae: a safety and efficacy study in the pig. J Vasc Res 2003 1.12
26 Arterial ultrastructure influences transport of locally delivered drugs. Circ Res 2002 1.11
27 Endothelial cells provide feedback control for vascular remodeling through a mechanosensitive autocrine TGF-beta signaling pathway. Circ Res 2008 1.11
28 Augmented expression and activity of extracellular matrix-degrading enzymes in regions of low endothelial shear stress colocalize with coronary atheromata with thin fibrous caps in pigs. Circulation 2011 1.11
29 Systemic inflammation induced by lipopolysaccharide increases neointimal formation after balloon and stent injury in rabbits. Circulation 2002 1.11
30 Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds? Circulation 2003 1.06
31 Glucose modulates basement membrane fibroblast growth factor-2 via alterations in endothelial cell permeability. J Biol Chem 2007 1.05
32 Cardiology is flow. Circulation 2006 1.04
33 Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts. J Vasc Surg 2007 1.04
34 Liposomal alendronate inhibits systemic innate immunity and reduces in-stent neointimal hyperplasia in rabbits. Circulation 2003 1.03
35 Impact of transport and drug properties on the local pharmacology of drug-eluting stents. Int J Cardiovasc Intervent 2003 1.02
36 Dynamic flow alterations dictate leukocyte adhesion and response to endovascular interventions. J Clin Invest 2004 1.02
37 Matrix embedding alters the immune response against endothelial cells in vitro and in vivo. Circulation 2005 1.02
38 Lesion complexity determines arterial drug distribution after local drug delivery. J Control Release 2009 1.00
39 Smooth muscle cells orchestrate the endothelial cell response to flow and injury. Circulation 2010 1.00
40 The role of low endothelial shear stress in the conversion of atherosclerotic lesions from stable to unstable plaque. Curr Opin Cardiol 2009 0.98
41 Dysfunctional endothelial cells directly stimulate cancer inflammation and metastasis. Int J Cancer 2013 0.98
42 Thrombosis modulates arterial drug distribution for drug-eluting stents. Circulation 2005 0.98
43 Viscoelastic adhesive mechanics of aldehyde-mediated soft tissue sealants. Biomaterials 2008 0.97
44 Natural tissue microenvironmental conditions modulate adhesive material performance. Langmuir 2012 0.97
45 Regulation of endothelial cell proliferation by primary monocytes. Arterioscler Thromb Vasc Biol 2007 0.96
46 Tissue-engineered endothelial and epithelial implants differentially and synergistically regulate airway repair. Proc Natl Acad Sci U S A 2008 0.96
47 Thrombus causes fluctuations in arterial drug delivery from intravascular stents. J Control Release 2008 0.95
48 Matrix adherence of endothelial cells attenuates immune reactivity: induction of hyporesponsiveness in allo- and xenogeneic models. FASEB J 2007 0.94
49 Syndecan-4 proteoliposomes enhance fibroblast growth factor-2 (FGF-2)-induced proliferation, migration, and neovascularization of ischemic muscle. Proc Natl Acad Sci U S A 2012 0.94
50 Role of fluid dynamics and inflammation in intracranial aneurysm formation. Circulation 2014 0.93
51 Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques. Atherosclerosis 2008 0.93
52 Preclinical evaluation of drug-eluting stents for peripheral applications: recommendations from an expert consensus group. Circulation 2004 0.93
53 Cells in fluidic environments are sensitive to flow frequency. J Cell Physiol 2005 0.92
54 Endothelial immunogenicity--a matter of matrix microarchitecture. Thromb Haemost 2007 0.91
55 Endothelial cell-matrix interactions determine maturation of dendritic cells. Eur J Immunol 2007 0.90
56 Quasi-steady-state kinetics at enzyme and substrate concentrations in excess of the Michaelis-Menten constant. J Theor Biol 2006 0.90
57 Revascularization for coronary artery disease in diabetes mellitus: angioplasty, stents and coronary artery bypass grafting. Rev Endocr Metab Disord 2010 0.90
58 The evolution of endothelial regulatory paradigms in cancer biology and vascular repair. Cancer Res 2011 0.90
59 Transgenic expression of human C-reactive protein suppresses endothelial nitric oxide synthase expression and bioactivity after vascular injury. Am J Physiol Heart Circ Physiol 2007 0.90
60 Cell-matrix contact prevents recognition and damage of endothelial cells in states of heightened immunity. Circulation 2006 0.90
61 Leukocyte recruitment and expression of chemokines following different forms of vascular injury. Vasc Med 2003 0.90
62 Analysis of compartmental models of ligand-induced endocytosis. J Theor Biol 2004 0.89
63 The effect of three-dimensional matrix-embedding of endothelial cells on the humoral and cellular immune response. Semin Immunol 2008 0.89
64 Regulation of heparanase expression in coronary artery disease in diabetic, hyperlipidemic swine. Atherosclerosis 2010 0.89
65 Endosomal receptor kinetics determine the stability of intracellular growth factor signalling complexes. Biochem J 2007 0.88
66 Embolic protection with filtering or occlusion balloons during saphenous vein graft stenting retrieves identical volumes and sizes of particulate debris. Circulation 2004 0.87
67 Low background, pulsatile, in vitro flow circuit for modeling coronary implant thrombosis. J Biomech Eng 2002 0.87
68 A structural model that explains the effects of hyperglycemia on collagenolysis. Biophys J 2003 0.87
69 Anti-atherosclerotic therapy based on botanicals. Recent Pat Cardiovasc Drug Discov 2013 0.87
70 Augmentation of postswelling surgical sealant potential of adhesive hydrogels. J Biomed Mater Res A 2010 0.86
71 Phosphorylation-induced conformational changes in a mitogen-activated protein kinase substrate. Implications for tyrosine hydroxylase activation. J Biol Chem 2002 0.86
72 Proangiogenic stimulation of bone marrow endothelium engages mTOR and is inhibited by simultaneous blockade of mTOR and NF-kappaB. Blood 2005 0.86
73 Effect of pre-adsorbed proteins on attachment, proliferation, and function of endothelial cells. J Cell Physiol 2002 0.86
74 Acute rejection in vascularized composite allotransplantation. Curr Opin Organ Transplant 2014 0.86
75 Heparanase regulates thrombosis in vascular injury and stent-induced flow disturbance. J Am Coll Cardiol 2012 0.86
76 Mechanisms of tissue uptake and retention in zotarolimus-coated balloon therapy. Circulation 2013 0.85
77 The effect of substrate modulus on the growth and function of matrix-embedded endothelial cells. Biomaterials 2012 0.85
78 Pushing drug-eluting stents into uncharted territory: simpler than you think--more complex than you imagine. Circulation 2006 0.85
79 Impact of flow pulsatility on arterial drug distribution in stent-based therapy. J Control Release 2013 0.85
80 Tubular bridges for bronchial epithelial cell migration and communication. PLoS One 2010 0.85
81 Thin-capped atheromata with reduced collagen content in pigs develop in coronary arterial regions exposed to persistently low endothelial shear stress. Arterioscler Thromb Vasc Biol 2013 0.85
82 Local and systemic drug competition in drug-eluting stent tissue deposition properties. J Control Release 2005 0.85
83 Environmental influences on endovascular stent platelet reactivity: an in vitro comparison of stainless steel and gold surfaces. J Biomed Mater Res A 2004 0.85
84 C-reactive protein promotes monocyte-platelet aggregation: an additional link to the inflammatory-thrombotic intricacy. Eur J Haematol 2007 0.84
85 Collagen fragments modulate innate immunity. Exp Biol Med (Maywood) 2007 0.84
86 Stent elution rate determines drug deposition and receptor-mediated effects. J Control Release 2012 0.84
87 Primary monocytes regulate endothelial cell survival through secretion of angiopoietin-1 and activation of endothelial Tie2. Arterioscler Thromb Vasc Biol 2011 0.84
88 The role of scaffold microarchitecture in engineering endothelial cell immunomodulation. Biomaterials 2012 0.84
89 Cellular bridges: Routes for intercellular communication and cell migration. Commun Integr Biol 2010 0.84
90 Engineered arterial models to correlate blood flow to tissue biological response. Ann N Y Acad Sci 2012 0.83
91 Delivery site of perivascular endothelial cell matrices determines control of stenosis in a porcine femoral stent model. J Vasc Interv Radiol 2009 0.83
92 Assessment of material by-product fate from bioresorbable vascular scaffolds. Ann Biomed Eng 2011 0.83
93 Monocyte activation state regulates monocyte-induced endothelial proliferation through Met signaling. Blood 2010 0.83
94 On the validity of the quasi-steady state approximation of bimolecular reactions in solution. J Theor Biol 2005 0.83
95 Neointimal formation is reduced after arterial injury in human crp transgenic mice. Atherosclerosis 2008 0.83
96 Optimal control of blood glucose: the diabetic patient or the machine? Sci Transl Med 2010 0.83
97 Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery disease. Curr Opin Cardiol 2007 0.82
98 NF-kappaB activity in endothelial cells is modulated by cell substratum interactions and influences chemokine-mediated adhesion of natural killer cells. Cell Transplant 2009 0.82
99 High concentrations of drug in target tissues following local controlled release are utilized for both drug distribution and biologic effect: an example with epicardial inotropic drug delivery. J Control Release 2013 0.81
100 Intramuscular drug transport under mechanical loading: resonance between tissue function and uptake. J Control Release 2009 0.81
101 Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors. Circ Heart Fail 2009 0.81
102 Matrix-embedded endothelial cells are protected from the uremic milieu. Nephrol Dial Transplant 2011 0.80
103 Elevated fibroblast growth factor-2 increases tumor necrosis factor-alpha induced endothelial cell death in high glucose. J Cell Physiol 2008 0.80
104 Vascular regeneration by local growth factor release is self-limited by microvascular clearance. Circulation 2009 0.80
105 Activation of EphB2 and its ligands promotes vascular smooth muscle cell proliferation. J Biol Chem 2001 0.80
106 Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug. J Control Release 2012 0.79
107 Local epicardial inotropic drug delivery allows targeted pharmacologic intervention with preservation of myocardial loading conditions. J Pharm Sci 2011 0.79
108 Tuning adhesion failure strength for tissue-specific applications. Acta Biomater 2010 0.79
109 Structural biomechanics modulate intramuscular distribution of locally delivered drugs. J Biomech 2008 0.79
110 Function and mode of regulation of endothelial major histocompatibility complex class II. Cell Transplant 2009 0.78
111 Resonance energy transfer for assessing the molecular integrity of proteins for local delivery. Biotechnol Bioeng 2004 0.77
112 Targeted anti-inflammatory systemic therapy for restenosis: the Biorest Liposomal Alendronate with Stenting sTudy (BLAST)-a double blind, randomized clinical trial. Am Heart J 2012 0.77
113 T-helper 2 cells are essential for modulation of vascular repair by allogeneic endothelial cells. J Heart Lung Transplant 2009 0.77
114 Amyloid beta toxicity dependent upon endothelial cell state. Neurosci Lett 2008 0.76
115 Synergistic effect of local endothelial shear stress and systemic hypercholesterolemia on coronary atherosclerotic plaque progression and composition in pigs. Int J Cardiol 2013 0.76
116 Modifications of microvascular EC surface modulate phototoxicity of a porphycene anti-ICAM-1 immunoconjugate; therapeutic implications. Langmuir 2013 0.75
117 [Models of human vascular disease: is there an animal of la mancha?]. Rev Esp Cardiol 2011 0.75
118 Role of CABG in the management of obstructive coronary arterial disease in patients with diabetes mellitus. Curr Opin Pharmacol 2012 0.75
119 Encapsulated pheochromocytoma cells secrete potent noncatecholamine factors. Tissue Eng Part A 2009 0.75
120 Importance of receptor-targeted systems in the battle against atherosclerosis. Curr Pharm Des 2013 0.75
121 Letter by Joynt and Edelman regarding article, "Iatrogenic giant Osborn waves". Circulation 2011 0.75
122 Cell matrix contact modifies endothelial major histocompatibility complex class II expression in high-glucose environment. Am J Physiol Heart Circ Physiol 2013 0.75
123 Particulates from hydrophilic-coated guiding sheaths embolise to the brain. EuroIntervention 2016 0.75
124 Renal denervation for treatment of hypertension - will 2017 be the year of enlightenment? EuroIntervention 2017 0.75
125 Dose model for stent-based delivery of a radioactive compound for the treatment of restenosis in coronary arteries. Med Phys 2003 0.75
126 Twenty-Four-Hour Ex Vivo Perfusion with Acellular Solution Enables Successful Replantation of Porcine Forelimbs. Plast Reconstr Surg 2019 0.75
127 Arterial Remodeling and Endothelial Shear Stress Exhibit Significant Longitudinal Heterogeneity Along the Length of Coronary Plaques. JACC Cardiovasc Imaging 2016 0.75
128 Images in cardiovascular medicine. Acute ST depressions in a patient with idiopathic hypertrophic subaortic stenosis and normal coronary arteries. Circulation 2002 0.75
129 Echocardiographic capture of right ventricular wall rupture during inferior wall acute myocardial infarction. Am J Cardiol 2009 0.75
130 Ultra-hydrophilic stent platforms promote early vascular healing and minimise late tissue response: a potential alternative to second-generation drug-eluting stents. EuroIntervention 2017 0.75
131 Finite element analysis of stent implantation in a three-dimensional reconstructed arterial segment. Conf Proc IEEE Eng Med Biol Soc 2014 0.75
132 A rattle bag of science and the art of translation. Sci Transl Med 2011 0.75