Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21.
|
Nat Genet
|
2008
|
6.75
|
2
|
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
|
Science
|
2013
|
4.71
|
3
|
The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947.
|
J Pers Soc Psychol
|
2004
|
4.09
|
4
|
Identification of common variants associated with human hippocampal and intracranial volumes.
|
Nat Genet
|
2012
|
3.73
|
5
|
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
Nat Genet
|
2011
|
3.40
|
6
|
The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond.
|
BMC Geriatr
|
2007
|
3.33
|
7
|
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.
|
Nat Genet
|
2012
|
3.19
|
8
|
New gene functions in megakaryopoiesis and platelet formation.
|
Nature
|
2011
|
3.14
|
9
|
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
Nat Genet
|
2011
|
3.03
|
10
|
Cohort profile: the Lothian Birth Cohorts of 1921 and 1936.
|
Int J Epidemiol
|
2011
|
2.78
|
11
|
Seventy-five genetic loci influencing the human red blood cell.
|
Nature
|
2012
|
2.77
|
12
|
Childhood IQ, social class, deprivation, and their relationships with mortality and morbidity risk in later life: prospective observational study linking the Scottish Mental Survey 1932 and the Midspan studies.
|
Psychosom Med
|
2003
|
2.69
|
13
|
Genetic contributions to stability and change in intelligence from childhood to old age.
|
Nature
|
2012
|
2.63
|
14
|
Association between psychological distress and mortality: individual participant pooled analysis of 10 prospective cohort studies.
|
BMJ
|
2012
|
2.56
|
15
|
Age-associated cognitive decline.
|
Br Med Bull
|
2009
|
2.26
|
16
|
The association between telomere length, physical health, cognitive ageing, and mortality in non-demented older people.
|
Neurosci Lett
|
2006
|
2.14
|
17
|
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
|
Nat Genet
|
2012
|
2.12
|
18
|
Cognitive change and the APOE epsilon 4 allele.
|
Nature
|
2002
|
2.01
|
19
|
Brain aging, cognition in youth and old age and vascular disease in the Lothian Birth Cohort 1936: rationale, design and methodology of the imaging protocol.
|
Int J Stroke
|
2011
|
1.98
|
20
|
The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
|
Brain Imaging Behav
|
2014
|
1.90
|
21
|
Cognitive reserve and the neurobiology of cognitive aging.
|
Ageing Res Rev
|
2004
|
1.79
|
22
|
Multi-site genetic analysis of diffusion images and voxelwise heritability analysis: a pilot project of the ENIGMA-DTI working group.
|
Neuroimage
|
2013
|
1.78
|
23
|
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
|
Circulation
|
2013
|
1.77
|
24
|
Birth weight and cognitive ability in childhood: a systematic review.
|
Psychol Bull
|
2004
|
1.75
|
25
|
Cognitive aging, childhood intelligence, and the use of food supplements: possible involvement of n-3 fatty acids.
|
Am J Clin Nutr
|
2004
|
1.67
|
26
|
A general factor of brain white matter integrity predicts information processing speed in healthy older people.
|
J Neurosci
|
2010
|
1.67
|
27
|
Brain white matter hyperintensities: relative importance of vascular risk factors in nondemented elderly people.
|
Radiology
|
2005
|
1.60
|
28
|
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
|
Am J Respir Crit Care Med
|
2012
|
1.49
|
29
|
Age and gender differences in physical capability levels from mid-life onwards: the harmonisation and meta-analysis of data from eight UK cohort studies.
|
PLoS One
|
2011
|
1.45
|
30
|
Childhood cognitive ability and risk of late-onset Alzheimer and vascular dementia.
|
Neurology
|
2008
|
1.40
|
31
|
Are processing speed tasks biomarkers of cognitive aging?
|
Psychol Aging
|
2010
|
1.40
|
32
|
Physical fitness and lifetime cognitive change.
|
Neurology
|
2006
|
1.38
|
33
|
Body mass index, muscle strength and physical performance in older adults from eight cohort studies: the HALCyon programme.
|
PLoS One
|
2013
|
1.32
|
34
|
Discovery and fine mapping of serum protein loci through transethnic meta-analysis.
|
Am J Hum Genet
|
2012
|
1.29
|
35
|
Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder.
|
PLoS One
|
2011
|
1.27
|
36
|
Cognitive ability at age 11 and 70 years, information processing speed, and APOE variation: the Lothian Birth Cohort 1936 study.
|
Psychol Aging
|
2009
|
1.26
|
37
|
Stability and change in intelligence from age 11 to ages 70, 79, and 87: the Lothian Birth Cohorts of 1921 and 1936.
|
Psychol Aging
|
2011
|
1.25
|
38
|
Neuroprotective lifestyles and the aging brain: activity, atrophy, and white matter integrity.
|
Neurology
|
2012
|
1.24
|
39
|
Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities.
|
Neurology
|
2014
|
1.22
|
40
|
Plasma cortisol levels, brain volumes and cognition in healthy elderly men.
|
Psychoneuroendocrinology
|
2005
|
1.21
|
41
|
Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies.
|
Int J Geriatr Psychiatry
|
2014
|
1.21
|
42
|
Polygenic risk for schizophrenia is associated with cognitive change between childhood and old age.
|
Biol Psychiatry
|
2013
|
1.20
|
43
|
The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence.
|
Hum Mol Genet
|
2007
|
1.16
|
44
|
Evidence of inbreeding depression on human height.
|
PLoS Genet
|
2012
|
1.16
|
45
|
Telomere length and aging biomarkers in 70-year-olds: the Lothian Birth Cohort 1936.
|
Neurobiol Aging
|
2010
|
1.15
|
46
|
Common variants of large effect in F12, KNG1, and HRG are associated with activated partial thromboplastin time.
|
Am J Hum Genet
|
2010
|
1.15
|
47
|
n-3 Fatty acid erythrocyte membrane content, APOE varepsilon4, and cognitive variation: an observational follow-up study in late adulthood.
|
Am J Clin Nutr
|
2008
|
1.14
|
48
|
KLOTHO genotype and cognitive ability in childhood and old age in the same individuals.
|
Neurosci Lett
|
2005
|
1.14
|
49
|
Magnetic resonance spectroscopy and cognitive function in healthy elderly men.
|
Brain
|
2002
|
1.13
|
50
|
Searching for genetic influences on normal cognitive ageing.
|
Trends Cogn Sci
|
2004
|
1.12
|
51
|
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.
|
PLoS Genet
|
2013
|
1.12
|
52
|
Coordinated analysis of age, sex, and education effects on change in MMSE scores.
|
J Gerontol B Psychol Sci Soc Sci
|
2012
|
1.10
|
53
|
ACTN3 genotype, athletic status, and life course physical capability: meta-analysis of the published literature and findings from nine studies.
|
Hum Mutat
|
2011
|
1.10
|
54
|
A cytogenetic abnormality and rare coding variants identify ABCA13 as a candidate gene in schizophrenia, bipolar disorder, and depression.
|
Am J Hum Genet
|
2009
|
1.08
|
55
|
The functional COMT polymorphism, Val 158 Met, is associated with logical memory and the personality trait intellect/imagination in a cohort of healthy 79 year olds.
|
Neurosci Lett
|
2005
|
1.08
|
56
|
Genome-wide association uncovers shared genetic effects among personality traits and mood states.
|
Am J Med Genet B Neuropsychiatr Genet
|
2012
|
1.08
|
57
|
Whole genome association scan for genetic polymorphisms influencing information processing speed.
|
Biol Psychol
|
2010
|
1.07
|
58
|
Smaller left anterior cingulate cortex volumes are associated with impaired hypothalamic-pituitary-adrenal axis regulation in healthy elderly men.
|
J Clin Endocrinol Metab
|
2006
|
1.06
|
59
|
Reverse causation in activity-cognitive ability associations: the Lothian Birth Cohort 1936.
|
Psychol Aging
|
2011
|
1.06
|
60
|
Higher systolic blood pressure is associated with increased water diffusivity in normal-appearing white matter.
|
Stroke
|
2009
|
1.06
|
61
|
Brain white matter damage in aging and cognitive ability in youth and older age.
|
Neurobiol Aging
|
2013
|
1.06
|
62
|
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.
|
Am J Hum Genet
|
2012
|
1.05
|
63
|
Brain iron deposits are associated with general cognitive ability and cognitive aging.
|
Neurobiol Aging
|
2010
|
1.05
|
64
|
Association of KIBRA and memory.
|
Neurosci Lett
|
2009
|
1.05
|
65
|
Genetic predictors of fibrin D-dimer levels in healthy adults.
|
Circulation
|
2011
|
1.05
|
66
|
The stability of intelligence from age 11 to age 90 years: the Lothian birth cohort of 1921.
|
Psychol Sci
|
2013
|
1.04
|
67
|
Psychosocial factors and health as determinants of quality of life in community-dwelling older adults.
|
Qual Life Res
|
2011
|
1.03
|
68
|
Education is associated with higher later life IQ scores, but not with faster cognitive processing speed.
|
Psychol Aging
|
2012
|
1.03
|
69
|
The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease.
|
J Alzheimers Dis
|
2012
|
1.02
|
70
|
Childhood IQ, smoking, and cognitive change from age 11 to 64 years.
|
Addict Behav
|
2005
|
1.02
|
71
|
Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.
|
PLoS Genet
|
2013
|
1.02
|
72
|
Apolipoprotein e gene variability and cognitive functions at age 79: a follow-up of the Scottish mental survey of 1932.
|
Psychol Aging
|
2004
|
1.02
|
73
|
How the 1932 and 1947 mental surveys of Aberdeen schoolchildren provide a framework to explore the childhood origins of late onset disease and disability.
|
Maturitas
|
2011
|
1.00
|
74
|
Alcohol intake and cognitive abilities in old age: the Lothian Birth Cohort 1936 study.
|
Neuropsychology
|
2011
|
1.00
|
75
|
Reverse causation in the association between C-reactive protein and fibrinogen levels and cognitive abilities in an aging sample.
|
Psychosom Med
|
2009
|
0.99
|
76
|
Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory.
|
Behav Genet
|
2014
|
0.99
|
77
|
Childhood and current cognitive function in healthy 80-year-olds: a DT-MRI study.
|
Neuroreport
|
2003
|
0.99
|
78
|
Calibrating ADL-IADL scales to improve measurement accuracy and to extend the disability construct into the preclinical range: a systematic review.
|
BMC Geriatr
|
2011
|
0.99
|
79
|
Losing one's grip: a bivariate growth curve model of grip strength and nonverbal reasoning from age 79 to 87 years in the Lothian Birth Cohort 1921.
|
J Gerontol B Psychol Sci Soc Sci
|
2011
|
0.98
|
80
|
Inter-individual differences in fMRI entropy measurements in old age.
|
IEEE Trans Biomed Eng
|
2011
|
0.98
|
81
|
Cognitive and behavioural predictors of survival in Alzheimer disease: results from a sample of treated patients in a tertiary-referral memory clinic.
|
Int J Geriatr Psychiatry
|
2011
|
0.97
|
82
|
Variation in the uric acid transporter gene (SLC2A9) and memory performance.
|
Hum Mol Genet
|
2010
|
0.97
|
83
|
Geographical variation in dementia: systematic review with meta-analysis.
|
Int J Epidemiol
|
2012
|
0.96
|
84
|
A genome-wide search for genetic influences and biological pathways related to the brain's white matter integrity.
|
Neurobiol Aging
|
2012
|
0.96
|
85
|
Diabetes and life-long cognitive ability.
|
J Psychosom Res
|
2013
|
0.95
|
86
|
Detecting deficits of sustained visual attention in delirium.
|
J Neurol Neurosurg Psychiatry
|
2010
|
0.95
|
87
|
The associations between personality, diet and body mass index in older people.
|
Health Psychol
|
2011
|
0.95
|
88
|
A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.
|
BMC Genet
|
2007
|
0.95
|
89
|
Sex differences in reaction time mean and intraindividual variability across the life span.
|
Dev Psychol
|
2012
|
0.94
|
90
|
Delirium should be included in guidelines and curriculums.
|
BMJ
|
2007
|
0.93
|
91
|
Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.
|
PLoS One
|
2009
|
0.92
|
92
|
Caffeine consumption and cognitive function at age 70: the Lothian Birth Cohort 1936 study.
|
Psychosom Med
|
2009
|
0.92
|
93
|
Brain white matter tract integrity and cognitive abilities in community-dwelling older people: the Lothian Birth Cohort, 1936.
|
Neuropsychology
|
2013
|
0.92
|
94
|
The association between retinal vascular network geometry and cognitive ability in an elderly population.
|
Invest Ophthalmol Vis Sci
|
2007
|
0.92
|
95
|
Telomere length and physical performance at older ages: an individual participant meta-analysis.
|
PLoS One
|
2013
|
0.92
|
96
|
Modeling multisystem biological risk in later life: allostatic load in the Lothian birth cohort study 1936.
|
Am J Hum Biol
|
2013
|
0.91
|
97
|
Genetic influences on oxidative stress and their association with normal cognitive ageing.
|
Neurosci Lett
|
2005
|
0.91
|
98
|
Pathways from childhood intelligence and socioeconomic status to late-life cardiovascular disease risk.
|
Health Psychol
|
2012
|
0.90
|
99
|
Socioeconomic status as a risk factor for dementia death: individual participant meta-analysis of 86 508 men and women from the UK.
|
Br J Psychiatry
|
2013
|
0.90
|
100
|
Cytomegalovirus infection and cognitive abilities in old age.
|
Neurobiol Aging
|
2013
|
0.90
|
101
|
Personality traits and inflammation in men and women in their early 70s: the Lothian Birth Cohort 1936 study of healthy aging.
|
Psychosom Med
|
2012
|
0.90
|
102
|
Psychological distress as a risk factor for dementia death.
|
Arch Intern Med
|
2011
|
0.90
|
103
|
Which social network or support factors are associated with cognitive abilities in old age?
|
Gerontology
|
2013
|
0.90
|
104
|
Psychological and physical health at age 70 in the Lothian Birth Cohort 1936: links with early life IQ, SES, and current cognitive function and neighborhood environment.
|
Health Psychol
|
2011
|
0.89
|
105
|
Does the Framingham cardiovascular disease risk score also have predictive utility for dementia death? An individual participant meta-analysis of 11,887 men and women.
|
Atherosclerosis
|
2013
|
0.89
|
106
|
Epigenetic Signatures of Cigarette Smoking.
|
Circ Cardiovasc Genet
|
2016
|
0.88
|
107
|
Apolipoprotein E is not related to memory abilities at 70 years of age.
|
Behav Genet
|
2008
|
0.88
|
108
|
Genetic enhancement of cognition in a kindred with cone-rod dystrophy due to RIMS1 mutation.
|
J Med Genet
|
2007
|
0.88
|
109
|
Nicastrin gene polymorphisms, cognitive ability level and cognitive ageing.
|
Neurosci Lett
|
2005
|
0.88
|
110
|
Differences in the haematological profile of healthy 70 year old men and women: normal ranges with confirmatory factor analysis.
|
BMC Blood Disord
|
2010
|
0.87
|
111
|
Age differences in intra-individual variability in simple and choice reaction time: systematic review and meta-analysis.
|
PLoS One
|
2012
|
0.87
|
112
|
Is body mass index in old age related to cognitive abilities? The Lothian Birth Cohort 1936 Study.
|
Psychol Aging
|
2010
|
0.87
|
113
|
Do dietary patterns influence cognitive function in old age?
|
Int Psychogeriatr
|
2013
|
0.87
|
114
|
Maximum (prior) brain size, not atrophy, correlates with cognition in community-dwelling older people: a cross-sectional neuroimaging study.
|
BMC Geriatr
|
2009
|
0.87
|
115
|
Changes in sensitivity patterns to selected antibiotics in Clostridium difficile in geriatric in-patients over an 18-month period.
|
J Med Microbiol
|
2003
|
0.86
|
116
|
The structure of the Hospital Anxiety and Depression Scale in four cohorts of community-based, healthy older people: the HALCyon program.
|
Int Psychogeriatr
|
2010
|
0.86
|
117
|
No association of CETP genotype with cognitive function or age-related cognitive change.
|
Neurosci Lett
|
2007
|
0.86
|
118
|
Associations between childhood intelligence (IQ), adult morbidity and mortality.
|
Maturitas
|
2009
|
0.86
|
119
|
Systemic antibody response to Clostridium difficile in colonized patients with and without symptoms and matched controls.
|
J Med Microbiol
|
2008
|
0.86
|
120
|
Alzheimer's disease genes are associated with measures of cognitive ageing in the lothian birth cohorts of 1921 and 1936.
|
Int J Alzheimers Dis
|
2011
|
0.86
|
121
|
ADRB2, brain white matter integrity and cognitive ageing in the Lothian Birth Cohort 1936.
|
Behav Genet
|
2012
|
0.86
|
122
|
Association of existing and new candidate genes for anxiety, depression and personality traits in older people.
|
Behav Genet
|
2010
|
0.86
|
123
|
Lack of association between polymorphisms in angiotensin-converting-enzyme and methylenetetrahydrofolate reductase genes and normal cognitive ageing in humans.
|
Neurosci Lett
|
2003
|
0.85
|
124
|
Dementia research--what do different public groups want? A survey by the Scottish Dementia Clinical Research Network.
|
Dementia (London)
|
2011
|
0.85
|
125
|
Predicting mortality from human faces.
|
Psychosom Med
|
2012
|
0.85
|
126
|
Quality of Life in healthy old age: relationships with childhood IQ, minor psychological symptoms and optimism.
|
Soc Psychiatry Psychiatr Epidemiol
|
2003
|
0.85
|
127
|
Depressive symptoms and diet: their effects on prospective inflammation levels in the elderly.
|
Brain Behav Immun
|
2011
|
0.85
|
128
|
Evolutionary conserved longevity genes and human cognitive abilities in elderly cohorts.
|
Eur J Hum Genet
|
2011
|
0.85
|
129
|
Brain lesions, hypertension and cognitive ageing in the 1921 and 1936 Aberdeen birth cohorts.
|
Age (Dordr)
|
2011
|
0.84
|
130
|
Alcohol consumption and lifetime change in cognitive ability: a gene × environment interaction study.
|
Age (Dordr)
|
2014
|
0.84
|
131
|
The ATXN1 and TRIM31 genes are related to intelligence in an ADHD background: evidence from a large collaborative study totaling 4,963 subjects.
|
Am J Med Genet B Neuropsychiatr Genet
|
2010
|
0.84
|
132
|
Age at natural menopause and cognition.
|
Maturitas
|
2004
|
0.84
|
133
|
Birth parameters and cognitive ability in older age: a follow-up study of people born 1921-1926.
|
Gerontology
|
2008
|
0.84
|
134
|
Seropositivity for CMV and IL-6 levels are associated with grip strength and muscle size in the elderly.
|
Immun Ageing
|
2013
|
0.83
|
135
|
Testing replication of a 5-SNP set for general cognitive ability in six population samples.
|
Eur J Hum Genet
|
2008
|
0.83
|
136
|
Glycosylated hemoglobin levels in healthy elderly nondiabetic men are negatively associated with verbal memory.
|
J Am Geriatr Soc
|
2004
|
0.83
|
137
|
Thyroid stimulating hormone, free thyroxine and cognitive ability in old age: the Lothian Birth Cohort Study 1936.
|
Psychoneuroendocrinology
|
2012
|
0.83
|
138
|
Modifiable cardiovascular disease risk factors as predictors of dementia death: pooling of ten general population-based cohort studies.
|
J Negat Results Biomed
|
2014
|
0.83
|
139
|
Brain volume and survival from age 78 to 85: the contribution of Alzheimer-type magnetic resonance imaging findings.
|
J Am Geriatr Soc
|
2010
|
0.83
|
140
|
Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking.
|
PLoS One
|
2010
|
0.83
|
141
|
Incidental findings on brain MR imaging in older community-dwelling subjects are common but serious medical consequences are rare: a cohort study.
|
PLoS One
|
2013
|
0.83
|
142
|
PPARG Pro12Ala genotype and risk of cognitive decline in elders? Maybe with diabetes.
|
Neurosci Lett
|
2008
|
0.83
|
143
|
Genetic copy number variation and general cognitive ability.
|
PLoS One
|
2012
|
0.83
|
144
|
11β-hydroxysteroid dehydrogenase type 1, brain atrophy and cognitive decline.
|
Neurobiol Aging
|
2010
|
0.83
|
145
|
Size of the neocerebellar vermis is associated with cognition in healthy elderly men.
|
Brain Cogn
|
2004
|
0.83
|
146
|
Birth parameters are associated with late-life white matter integrity in community-dwelling older people.
|
Stroke
|
2009
|
0.82
|
147
|
Cognitive function in childhood and lifetime cognitive change in relation to mental wellbeing in four cohorts of older people.
|
PLoS One
|
2012
|
0.82
|
148
|
Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme.
|
Aging Cell
|
2011
|
0.82
|
149
|
Design and validation of a novel method to measure cross-sectional area of neck muscles included during routine MR brain volume imaging.
|
PLoS One
|
2012
|
0.81
|
150
|
Profiles of physical, emotional and psychosocial wellbeing in the Lothian birth cohort 1936.
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