Published in J Am Chem Soc on March 31, 2010
Effects of curvature and composition on α-synuclein binding to lipid vesicles. Biophys J (2010) 1.71
Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins. J Biol Chem (2010) 1.69
Impact of N-terminal acetylation of α-synuclein on its random coil and lipid binding properties. Biochemistry (2012) 1.44
Alpha-synuclein populates both elongated and broken helix states on small unilamellar vesicles. J Biol Chem (2011) 1.31
Single molecule characterization of α-synuclein in aggregation-prone states. Biophys J (2010) 1.09
Biophysics of α-synuclein membrane interactions. Biochim Biophys Acta (2011) 1.08
Remodeling of lipid vesicles into cylindrical micelles by α-synuclein in an extended α-helical conformation. J Biol Chem (2012) 1.07
Soluble, prefibrillar α-synuclein oligomers promote complex I-dependent, Ca2+-induced mitochondrial dysfunction. J Biol Chem (2014) 1.00
Biophysical insights into how surfaces, including lipid membranes, modulate protein aggregation related to neurodegeneration. Front Neurol (2013) 0.96
α-Synuclein oligomers with broken helical conformation form lipoprotein nanoparticles. J Biol Chem (2013) 0.95
NMR determination of pKa values in α-synuclein. Protein Sci (2010) 0.94
Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state. Biophys J (2012) 0.87
Electron paramagnetic resonance spectroscopy measures the distance between the external β-strands of folded α-synuclein in amyloid fibrils. Biophys J (2011) 0.83
Characterization of a disordered protein during micellation: interactions of α-synuclein with sodium dodecyl sulfate. J Phys Chem B (2012) 0.83
Long-range distances in amyloid fibrils of α-synuclein from PELDOR spectroscopy. Angew Chem Int Ed Engl (2013) 0.81
Function and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescence. Mol Neurobiol (2012) 0.77
Membrane remodeling by amyloidogenic and non-amyloidogenic proteins studied by EPR. J Magn Reson (2017) 0.75
SNARE assembly and disassembly exhibit a pronounced hysteresis. Nat Struct Biol (2002) 2.40
Dependence of alpha-synuclein aggregate morphology on solution conditions. J Mol Biol (2002) 2.26
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio. EMBO J (2010) 2.26
Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro. Biochemistry (2004) 1.77
Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein. J Am Chem Soc (2008) 1.45
NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation. EMBO J (2004) 1.41
Micromechanical bending of single collagen fibrils using atomic force microscopy. J Biomed Mater Res A (2007) 1.38
Dynamic fluorescence anisotropy imaging microscopy in the frequency domain (rFLIM). Biophys J (2002) 1.34
Rapid self-assembly of alpha-synuclein observed by in situ atomic force microscopy. J Mol Biol (2004) 1.24
Cellular polyamines promote the aggregation of alpha-synuclein. J Biol Chem (2002) 1.21
Fast, ultrasensitive virus detection using a Young interferometer sensor. Nano Lett (2007) 1.21
Lipid bilayer disruption by oligomeric alpha-synuclein depends on bilayer charge and accessibility of the hydrophobic core. Biochim Biophys Acta (2009) 1.20
Nanomechanical properties of α-synuclein amyloid fibrils: a comparative study by nanoindentation, harmonic force microscopy, and Peakforce QNM. Nanoscale Res Lett (2011) 1.16
Refractive index sensing of green fluorescent proteins in living cells using fluorescence lifetime imaging microscopy. Biophys J (2008) 1.14
Covalent microcontact printing of proteins for cell patterning. Chemistry (2006) 1.12
Identifying protein construct variants with increased crystallization propensity--a case study. Protein Sci (2006) 1.12
Resonance energy transfer in a calcium concentration-dependent cameleon protein. Biophys J (2002) 1.12
Quantitative morphological analysis reveals ultrastructural diversity of amyloid fibrils from alpha-synuclein mutants. Biophys J (2006) 1.12
Direct evidence of coexisting horseshoe and extended helix conformations of membrane-bound alpha-synuclein. Chemphyschem (2010) 1.08
Spin-label EPR on alpha-synuclein reveals differences in the membrane binding affinity of the two antiparallel helices. Chembiochem (2008) 1.08
EPR characterization of the mononuclear Cu-containing Aspergillus japonicus quercetin 2,3-dioxygenase reveals dramatic changes upon anaerobic binding of substrates. Eur J Biochem (2002) 1.07
Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism. PLoS One (2010) 1.05
The ubiquitin-specific protease USP10 modulates androgen receptor function. Mol Cell Endocrinol (2005) 1.03
Structural basis for a high affinity inhibitor bound to protein kinase MK2. J Mol Biol (2007) 1.01
Direct observation of nanomechanical properties of chromatin in living cells. Nano Lett (2007) 0.99
Oligomerization of DsRed is required for the generation of a functional red fluorescent chromophore. FEBS Lett (2002) 0.99
Concentration dependence of alpha-synuclein fibril length assessed by quantitative atomic force microscopy and statistical-mechanical theory. Biophys J (2008) 0.98
Distances between the b-subunits in the tether domain of F(0)F(1)-ATP synthase from E. coli. Biochim Biophys Acta (2005) 0.98
Membrane binding of oligomeric alpha-synuclein depends on bilayer charge and packing. FEBS Lett (2008) 0.97
Distance between a native cofactor and a spin label in the reaction centre of Rhodobacter sphaeroides by a two-frequency pulsed electron paramagnetic resonance method and molecular dynamics simulations. J Magn Reson (2006) 0.94
Single-molecule FRET reveals structural heterogeneity of SDS-bound alpha-synuclein. Chembiochem (2009) 0.94
Nanometer arrays of functional light harvesting antenna complexes by nanoimprint lithography and host-guest interactions. J Am Chem Soc (2008) 0.94
Force spectroscopy and fluorescence microscopy of dsDNA-YOYO-1 complexes: implications for the structure of dsDNA in the overstretching region. Nucleic Acids Res (2010) 0.91
Molecular plasticity regulates oligomerization and cytotoxicity of the multipeptide-length amyloid-β peptide pool. J Biol Chem (2012) 0.90
Creating nanopatterns of His-tagged proteins on surfaces by nanoimprint lithography using specific NiNTA-histidine interactions. Small (2007) 0.90
Hunting the chameleon: structural conformations of the intrinsically disordered protein alpha-synuclein. Chembiochem (2012) 0.89
Accurate long-range distance measurements in a doubly spin-labeled protein by a four-pulse, double electron-electron resonance method. Magn Reson Chem (2008) 0.89
High-field (275 GHz) spin-label EPR for high-resolution polarity determination in proteins. J Magn Reson (2006) 0.89
Tissue transglutaminase modulates alpha-synuclein oligomerization. Protein Sci (2008) 0.88
Integrin-dependent activation of the JNK signaling pathway by mechanical stress. PLoS One (2011) 0.88
Molecular composition of sub-stoichiometrically labeled α-synuclein oligomers determined by single-molecule photobleaching. Angew Chem Int Ed Engl (2012) 0.87
Directed formation of micro- and nanoscale patterns of functional light-harvesting LH2 complexes. J Am Chem Soc (2007) 0.87
Spin-density distribution in the copper site of azurin. Chemphyschem (2006) 0.87
Long-range energy propagation in nanometer arrays of light harvesting antenna complexes. Nano Lett (2010) 0.87
Measurement of a Cu-Cu distance of 26 A by a pulsed EPR method. Angew Chem Int Ed Engl (2003) 0.87
Room temperature excitation spectroscopy of single quantum dots. Beilstein J Nanotechnol (2011) 0.86
Spatially resolved frequency-dependent elasticity measured with pulsed force microscopy and nanoindentation. Nanoscale (2012) 0.86
Inhibition of α-synuclein aggregation by small heat shock proteins. Proteins (2011) 0.86
Room temperature spectrally resolved single-molecule spectroscopy reveals new spectral forms and photophysical versatility of aequorea green fluorescent protein variants. Biophys J (2004) 0.86
α-Synuclein oligomers: an amyloid pore? Insights into mechanisms of α-synuclein oligomer-lipid interactions. Mol Neurobiol (2012) 0.86
Atomic force microscopy under controlled conditions reveals structure of C-terminal region of α-synuclein in amyloid fibrils. ACS Nano (2012) 0.86
Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability. Eur J Biochem (2003) 0.86
Alpha-synuclein binds to the inner membrane of mitochondria in an α-helical conformation. Chembiochem (2014) 0.85
Nanophotonic control of the Förster resonance energy transfer efficiency. Phys Rev Lett (2012) 0.85
Microbioreactors for Raman microscopy of stromal cell differentiation. Anal Chem (2010) 0.85
New insights into the photophysics of DsRed by multiparameter spectroscopy on single proteins. J Phys Chem B (2008) 0.85
Double-stranded DNA stimulates the fibrillation of alpha-synuclein in vitro and is associated with the mature fibrils: an electron microscopy study. J Mol Biol (2004) 0.84
Aggregation of transmembrane peptides studied by spin-label EPR. J Phys Chem B (2009) 0.84
Biofunctionalized lipid-polymer hybrid nanocontainers with controlled permeability. Nano Lett (2008) 0.84
Syntenin-1 and ezrin proteins link activated leukocyte cell adhesion molecule to the actin cytoskeleton. J Biol Chem (2014) 0.83
Single-molecule spectroscopy of fluorescent proteins. Anal Bioanal Chem (2008) 0.83
Membrane interactions of oligomeric alpha-synuclein: potential role in Parkinson's disease. Curr Protein Pept Sci (2010) 0.83
Strategies for patterning biomolecules with dip-pen nanolithography. Small (2011) 0.83
Membrane interactions and fibrillization of α-synuclein play an essential role in membrane disruption. FEBS Lett (2014) 0.82
Anchoring of histidine-tagged proteins to molecular printboards: self-assembly, thermodynamic modeling, and patterning. Chemistry (2008) 0.82
A comparative analysis of the aggregation behavior of amyloid-β peptide variants. FEBS Lett (2012) 0.82
A pulsed EPR method to determine distances between paramagnetic centers with strong spectral anisotropy and radicals: the dead-time free RIDME sequence. J Magn Reson (2009) 0.81
Intracellular manipulation of chromatin using magnetic nanoparticles. Chromosome Res (2008) 0.81
α-Synuclein oligomers distinctively permeabilize complex model membranes. FEBS J (2014) 0.81
An isolated nitridyl radical-bridged {Rh(N·)Rh} complex. Angew Chem Int Ed Engl (2014) 0.81
A molecular beacon strategy for real-time monitoring of triplex DNA formation kinetics. Antisense Nucleic Acid Drug Dev (2002) 0.81
Resonance CARS study of the structure of "green" and "red" chromophores within the red fluorescent protein DsRed. J Am Chem Soc (2002) 0.80
Amyloid fibrils from the mammalian protein prothymosin alpha. FEBS Lett (2002) 0.80
Single-crystal EPR study at 95 GHz of the type 2 copper site of the inhibitor-bound quercetin 2,3-dioxygenase. Biophys J (2003) 0.80
Manipulation of the local density of photonic states to elucidate fluorescent protein emission rates. Phys Chem Chem Phys (2009) 0.80
Directed assembly of functional light harvesting antenna complexes onto chemically patterned surfaces. Nanotechnology (2007) 0.80
Reconstitution of the type-1 active site of the H145G/A variants of nitrite reductase by ligand insertion. Biochemistry (2003) 0.80
Kinetic measurements give new insights into lipid membrane permeabilization by α-synuclein oligomers. Mol Biosyst (2011) 0.80
Oriented protein immobilization using covalent and noncovalent chemistry on a thiol-reactive self-reporting surface. J Am Chem Soc (2013) 0.80
In silico interpretation of cw-ESR at 9 and 95 GHz of mono- and bis- TOAC-labeled Aib-homopeptides in fluid and frozen acetonitrile. J Phys Chem B (2011) 0.79
Quantitative characterization of protein nanostructures using atomic force microscopy. Conf Proc IEEE Eng Med Biol Soc (2007) 0.79
Identification, cloning and characterization of a new DNA-binding protein from the hyperthermophilic methanogen Methanopyrus kandleri. Nucleic Acids Res (2002) 0.79
Patterning of peptide nucleic acids using reactive microcontact printing. Langmuir (2010) 0.79
Fibril breaking accelerates α-synuclein fibrillization. J Phys Chem B (2015) 0.78
Expression of sensitized Eu(3+) luminescence at a multivalent interface. J Am Chem Soc (2009) 0.78
The complex of cytochrome f and plastocyanin from Nostoc sp. PCC 7119 is highly dynamic. Chembiochem (2012) 0.78
Self-assembly of protein fibrils into suprafibrillar aggregates: bridging the nano- and mesoscale. ACS Nano (2014) 0.78
Assembly of bionanostructures onto beta-cyclodextrin molecular printboards for antibody recognition and lymphocyte cell counting. J Am Chem Soc (2008) 0.78
Fabrication of cell container arrays with overlaid surface topographies. Biomed Microdevices (2012) 0.78