Published in Eur J Biochem on June 01, 2002
Copper active sites in biology. Chem Rev (2014) 1.90
Anaerobic enzyme.substrate structures provide insight into the reaction mechanism of the copper-dependent quercetin 2,3-dioxygenase. Proc Natl Acad Sci U S A (2002) 1.18
Ring-cleaving dioxygenases with a cupin fold. Appl Environ Microbiol (2012) 1.06
O2-dependent aliphatic carbon-carbon bond cleavage reactivity in a Ni(II) enolate complex having a hydrogen bond donor microenvironment; comparison with a hydrophobic analogue. Inorg Chem (2010) 0.82
Single-crystal EPR study at 95 GHz of the type 2 copper site of the inhibitor-bound quercetin 2,3-dioxygenase. Biophys J (2003) 0.80
Structure and function of atypically coordinated enzymatic mononuclear non-heme-Fe(II) centers. Coord Chem Rev (2013) 0.79
Nickel quercetinase, a "promiscuous" metalloenzyme: metal incorporation and metal ligand substitution studies. BMC Biochem (2015) 0.78
Characterization of Cu(II)-ACC complexes and conversion of the bound ACC into ethylene in the presence of hydrogen peroxide. detection of a brown intermediate at low temperature. Bioinorg Chem Appl (2007) 0.75
Electron paramagnetic resonance spectroscopic study of copper hopping in doped bis(L-histidinato)cadmium dihydrate. J Phys Chem A (2013) 0.75
REFMAC5 for the refinement of macromolecular crystal structures. Acta Crystallogr D Biol Crystallogr (2011) 39.32
REFMAC5 dictionary: organization of prior chemical knowledge and guidelines for its use. Acta Crystallogr D Biol Crystallogr (2004) 14.28
Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins. J Biol Chem (2002) 1.71
Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations. J Mol Biol (2003) 1.59
Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39. J Biol Chem (2003) 1.56
Crystal structure of Agaricus bisporus mushroom tyrosinase: identity of the tetramer subunits and interaction with tropolone. Biochemistry (2011) 1.49
Antiparallel arrangement of the helices of vesicle-bound alpha-synuclein. J Am Chem Soc (2008) 1.45
Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice. Endocrinology (2011) 1.37
Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations. Proc Natl Acad Sci U S A (2010) 1.29
Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus. J Mol Biol (2003) 1.28
ABC lipid transporters: extruders, flippases, or flopless activators? FEBS Lett (2005) 1.27
Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus. Structure (2002) 1.22
Anaerobic enzyme.substrate structures provide insight into the reaction mechanism of the copper-dependent quercetin 2,3-dioxygenase. Proc Natl Acad Sci U S A (2002) 1.18
Cofactor-independent oxidases and oxygenases. Appl Microbiol Biotechnol (2010) 1.17
The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily. J Biol Chem (2003) 1.15
Crystal structure and catalytic mechanism of the LPS 3-O-deacylase PagL from Pseudomonas aeruginosa. Proc Natl Acad Sci U S A (2006) 1.15
Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes. Proc Natl Acad Sci U S A (2010) 1.12
Identifying protein construct variants with increased crystallization propensity--a case study. Protein Sci (2006) 1.12
Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate. J Biol Chem (2006) 1.12
Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase. J Biol Chem (2007) 1.12
Lipopolysaccharide regions involved in the activation of Escherichia coli outer membrane protease OmpT. Eur J Biochem (2002) 1.11
Glucansucrases: three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications. J Biotechnol (2012) 1.10
Novel Hsp90 partners discovered using complementary proteomic approaches. Cell Stress Chaperones (2009) 1.09
Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon-halogen bond. Curr Opin Struct Biol (2003) 1.08
Spin-label EPR on alpha-synuclein reveals differences in the membrane binding affinity of the two antiparallel helices. Chembiochem (2008) 1.08
Direct evidence of coexisting horseshoe and extended helix conformations of membrane-bound alpha-synuclein. Chemphyschem (2010) 1.08
Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis. Eur J Biochem (2002) 1.07
Functional analysis of the copper-dependent quercetin 2,3-dioxygenase. 1. Ligand-induced coordination changes probed by X-ray crystallography: inhibition, ordering effect, and mechanistic insights. Biochemistry (2002) 1.07
A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: structural determinants of redox potential. Protein Sci (2005) 1.06
Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage. J Biol Chem (2007) 1.05
The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases. J Biol Chem (2003) 1.04
Structure of Spa15, a type III secretion chaperone from Shigella flexneri with broad specificity. EMBO Rep (2004) 1.03
The ubiquitin-specific protease USP10 modulates androgen receptor function. Mol Cell Endocrinol (2005) 1.03
Crystal structure of MltA from Escherichia coli reveals a unique lytic transglycosylase fold. J Mol Biol (2005) 1.02
The quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket. Proc Natl Acad Sci U S A (2009) 1.02
A stable lipid-induced aggregate of alpha-synuclein. J Am Chem Soc (2010) 1.01
Structural basis for a high affinity inhibitor bound to protein kinase MK2. J Mol Biol (2007) 1.01
A functional screen identifies specific microRNAs capable of inhibiting human melanoma cell viability. PLoS One (2012) 1.00
Distances between the b-subunits in the tether domain of F(0)F(1)-ATP synthase from E. coli. Biochim Biophys Acta (2005) 0.98
Two major archaeal pseudomurein endoisopeptidases: PeiW and PeiP. Archaea (2010) 0.98
Structural insights into the processivity of endopolygalacturonase I from Aspergillus niger. FEBS Lett (2003) 0.97
Structural basis for kinesin-1:cargo recognition. Science (2013) 0.97
Mutations converting cyclodextrin glycosyltransferase from a transglycosylase into a starch hydrolase. FEBS Lett (2002) 0.97
Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution. Biochem J (2008) 0.96
Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex. Proc Natl Acad Sci U S A (2010) 0.95
Distance between a native cofactor and a spin label in the reaction centre of Rhodobacter sphaeroides by a two-frequency pulsed electron paramagnetic resonance method and molecular dynamics simulations. J Magn Reson (2006) 0.94
Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme. J Biol Chem (2005) 0.93
Functional and structural characterization of α-(1->2) branching sucrase derived from DSR-E glucansucrase. J Biol Chem (2012) 0.93
Structure of the α-1,6/α-1,4-specific glucansucrase GTFA from Lactobacillus reuteri 121. Acta Crystallogr Sect F Struct Biol Cryst Commun (2012) 0.92
Structural and mutational characterization of the catalytic A-module of the mannuronan C-5-epimerase AlgE4 from Azotobacter vinelandii. J Biol Chem (2008) 0.92
Murein and pseudomurein cell wall binding domains of bacteria and archaea--a comparative view. Appl Microbiol Biotechnol (2011) 0.91
Crystal structure of quinohemoprotein alcohol dehydrogenase from Comamonas testosteroni: structural basis for substrate oxidation and electron transfer. J Biol Chem (2001) 0.90
Active-site architecture and catalytic mechanism of the lipid A deacylase LpxR of Salmonella typhimurium. Proc Natl Acad Sci U S A (2009) 0.90
Hunting the chameleon: structural conformations of the intrinsically disordered protein alpha-synuclein. Chembiochem (2012) 0.89
Escherichia coli MltA: MAD phasing and refinement of a tetartohedrally twinned protein crystal structure. Acta Crystallogr D Biol Crystallogr (2005) 0.89
Accurate long-range distance measurements in a doubly spin-labeled protein by a four-pulse, double electron-electron resonance method. Magn Reson Chem (2008) 0.89
Acetobacter turbidans alpha-amino acid ester hydrolase: merohedral twinning in P21 obscured by pseudo-translational NCS. Acta Crystallogr D Biol Crystallogr (2003) 0.89
Identification of acceptor substrate binding subsites +2 and +3 in the amylomaltase from Thermus thermophilus HB8. Biochemistry (2007) 0.89
High-field (275 GHz) spin-label EPR for high-resolution polarity determination in proteins. J Magn Reson (2006) 0.89
Structures of an isopenicillin N converting Ntn-hydrolase reveal different catalytic roles for the active site residues of precursor and mature enzyme. Structure (2010) 0.88
AcmD, a homolog of the major autolysin AcmA of Lactococcus lactis, binds to the cell wall and contributes to cell separation and autolysis. PLoS One (2013) 0.88
Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site. Biochemistry (2005) 0.88
The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism. J Biol Chem (2001) 0.87
Measurement of a Cu-Cu distance of 26 A by a pulsed EPR method. Angew Chem Int Ed Engl (2003) 0.87
Spin-density distribution in the copper site of azurin. Chemphyschem (2006) 0.87
Conversion of cyclodextrin glycosyltransferase into a starch hydrolase by directed evolution: the role of alanine 230 in acceptor subsite +1. Biochemistry (2003) 0.87
The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. J Bacteriol (2006) 0.86
Structural basis of phospholipase activity of Staphylococcus hyicus lipase. J Mol Biol (2007) 0.86
Functional analysis of the copper-dependent quercetin 2,3-dioxygenase. 2. X-ray absorption studies of native enzyme and anaerobic complexes with the substrates quercetin and myricetin. Biochemistry (2002) 0.86
Origin of the proton-transfer step in the cofactor-free (1H)-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase: effect of the basicity of an active site His residue. J Biol Chem (2014) 0.86
Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain. J Mol Biol (2008) 0.86
Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri. EMBO Rep (2006) 0.86
Variable role of ions in two drug intercalation complexes of DNA. J Biol Inorg Chem (2005) 0.86
Fortuitous structure determination of 'as-isolated' Escherichia coli bacterioferritin in a novel crystal form. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.86
The use of in vitro peptide binding profiles and in silico ligand-receptor interaction profiles to describe ligand-induced conformations of the retinoid X receptor alpha ligand-binding domain. Mol Endocrinol (2006) 0.85
Improved thermostability of bacillus circulans cyclodextrin glycosyltransferase by the introduction of a salt bridge. Proteins (2004) 0.85
Engineering cyclodextrin glycosyltransferase into a starch hydrolase with a high exo-specificity. J Biotechnol (2003) 0.85
Synthesis of a novel fluorescent ceramide analogue and its use in the characterization of recombinant ceramidase from Pseudomonas aeruginosa PA01. Chem Phys Lipids (2002) 0.85
The fully conserved Asp residue in conserved sequence region I of the alpha-amylase family is crucial for the catalytic site architecture and activity. FEBS Lett (2003) 0.84
Reducing virulence of the human pathogen Burkholderia by altering the substrate specificity of the quorum-quenching acylase PvdQ. Proc Natl Acad Sci U S A (2014) 0.84
Structural basis for the enantioselectivity of an epoxide ring opening reaction catalyzed by halo alcohol dehalogenase HheC. J Am Chem Soc (2005) 0.84
Aggregation of transmembrane peptides studied by spin-label EPR. J Phys Chem B (2009) 0.84
Mechanism-inspired engineering of phenylalanine aminomutase for enhanced β-regioselective asymmetric amination of cinnamates. Angew Chem Int Ed Engl (2011) 0.83
Crystallization and preliminary X-ray crystallographic analysis of tyrosinase from the mushroom Agaricus bisporus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.83
A genetically engineered protein domain binding to bacterial murein, archaeal pseudomurein, and fungal chitin cell wall material. Appl Microbiol Biotechnol (2012) 0.83
Immediate protein targets of photodynamic treatment in carcinoma cells. J Proteome Res (2008) 0.83
A minimum of three motifs is essential for optimal binding of pseudomurein cell wall-binding domain of Methanothermobacter thermautotrophicus. PLoS One (2011) 0.83
Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases. Biochem J (2007) 0.82
Thermus thermophilus glycoside hydrolase family 57 branching enzyme: crystal structure, mechanism of action, and products formed. J Biol Chem (2010) 0.82
Glycolipid transfer protein: clear structure and activity, but enigmatic function. Adv Enzyme Regul (2007) 0.82
Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection. Chembiochem (2006) 0.82
Characterization of aptamer-protein complexes by X-ray crystallography and alternative approaches. Int J Mol Sci (2012) 0.82
Thermoanaerobacterium thermosulfurigenes cyclodextrin glycosyltransferase. Eur J Biochem (2003) 0.82
A pulsed EPR method to determine distances between paramagnetic centers with strong spectral anisotropy and radicals: the dead-time free RIDME sequence. J Magn Reson (2009) 0.81
An isolated nitridyl radical-bridged {Rh(N·)Rh} complex. Angew Chem Int Ed Engl (2014) 0.81
Crystal structure of inulosucrase from Lactobacillus: insights into the substrate specificity and product specificity of GH68 fructansucrases. J Mol Biol (2011) 0.81
The adsorption and unfolding kinetics determines the folding state of proteins at the air-water interface and thereby the equation of state. J Colloid Interface Sci (2006) 0.81