Published in BMC Biol on March 03, 2010
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A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors. Oncogene (2011) 1.00
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Rho family proteins and Ras transformation: the RHOad less traveled gets congested. Oncogene (1998) 1.99
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Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation. Blood (2001) 1.96
DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomas. Oncogene (2004) 1.90
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Rho-A is critical for osteoclast podosome organization, motility, and bone resorption. J Biol Chem (2000) 1.69
DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms. Mol Carcinog (2008) 1.67
Restoration of DLC-1 gene expression induces apoptosis and inhibits both cell growth and tumorigenicity in human hepatocellular carcinoma cells. Oncogene (2004) 1.65
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Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. DNA Res (2000) 1.33
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Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho. J Biol Chem (2003) 1.30
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Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho. J Biol Chem (1999) 1.14
A PLCdelta1-binding protein, p122/RhoGAP, is localized in caveolin-enriched membrane domains and regulates caveolin internalization. Genes Cells (2004) 1.14
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A PLCdelta1-binding protein, p122RhoGAP, is localized in focal adhesions. Biochem Soc Trans (2004) 1.06
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Analysis of promoter methylation and its role in silencing metallothionein I gene expression in tumor cells. Methods Enzymol (2002) 1.04
Unintentional miRNA ablation is a risk factor in gene knockout studies: a short report. PLoS Genet (2008) 1.03
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The SAM domain of the RhoGAP DLC1 binds EF1A1 to regulate cell migration. J Cell Sci (2009) 0.98
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Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma. Liver Int (2009) 0.88
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Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nat Neurosci (2012) 2.93
miR-34 miRNAs provide a barrier for somatic cell reprogramming. Nat Cell Biol (2011) 2.79
The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology. Curr Biol (2005) 2.53
TLS, EWS and TAF15: a model for transcriptional integration of gene expression. Brief Funct Genomic Proteomic (2006) 2.29
Delayed platelet engraftment in group O patients after autologous progenitor cell transplantation. Transfusion (2005) 1.39
Regulation of the cellular DNA double-strand break response. Biochem Cell Biol (2007) 1.31
The high-mobility-group box protein SSRP1/T160 is essential for cell viability in day 3.5 mouse embryos. Mol Cell Biol (2003) 1.21
Mechanisms of lung endothelial barrier disruption induced by cigarette smoke: role of oxidative stress and ceramides. Am J Physiol Lung Cell Mol Physiol (2011) 1.21
Superoxide dismutase protects against apoptosis and alveolar enlargement induced by ceramide. Am J Physiol Lung Cell Mol Physiol (2008) 1.17
A generalizable pre-clinical research approach for orphan disease therapy. Orphanet J Rare Dis (2012) 1.16
Lung endothelial monocyte-activating protein 2 is a mediator of cigarette smoke-induced emphysema in mice. J Clin Invest (2011) 1.10
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema. Am J Respir Crit Care Med (2009) 1.08
ALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation. PLoS Genet (2013) 1.07
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. J Biol Chem (2010) 1.04
Identification and characterization of protective epitope of Trichinella spiralis paramyosin. Vaccine (2011) 0.99
Demographic characteristics and risk behaviors associated with HIV positive injecting drug users in Xinjiang, China. J Infect (2006) 0.99
17-hydroxy-jolkinolide B inhibits signal transducers and activators of transcription 3 signaling by covalently cross-linking Janus kinases and induces apoptosis of human cancer cells. Cancer Res (2009) 0.98
Trichinella spiralis paramyosin binds to C8 and C9 and protects the tissue-dwelling nematode from being attacked by host complement. PLoS Negl Trop Dis (2011) 0.97
Molecular cloning and characterization of heat shock protein 70 from Trichinella spiralis. Acta Trop (2009) 0.97
Trichinella spiralis: immune response and protective immunity elicited by recombinant paramyosin formulated with different adjuvants. Exp Parasitol (2010) 0.95
Identification and characterization of a full-length cDNA encoding paramyosin of Trichinella spiralis. Biochem Biophys Res Commun (2007) 0.94
A Phase I study of an intravesically administered immunotoxin targeting EpCAM for the treatment of nonmuscle-invasive bladder cancer in BCGrefractory and BCG-intolerant patients. Drug Des Devel Ther (2010) 0.92
Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. Carcinogenesis (2008) 0.92
CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis. Am J Respir Cell Mol Biol (2009) 0.91
The emerging functions of the p53-miRNA network in stem cell biology. Cell Cycle (2012) 0.90
Insulin-like growth factor 3 regulates expression of genes encoding steroidogenic enzymes and key transcription factors in the Nile tilapia gonad. Biol Reprod (2012) 0.89
Mapping of the complement C9 binding domain on Trichinella spiralis paramyosin. Parasit Vectors (2014) 0.88
Activation of cryptic 3' splice sites within introns of cellular genes following gene entrapment. Nucleic Acids Res (2004) 0.86
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Monoclonal antibody targeting complement C9 binding domain of Trichinella spiralis paramyosin impairs the viability of Trichinella infective larvae in the presence of complement. Parasit Vectors (2014) 0.85
17-Acetoxyjolkinolide B irreversibly inhibits IkappaB kinase and induces apoptosis of tumor cells. Mol Cancer Ther (2008) 0.85
Duplication of Subcytoband 11E2 of Chromosome 11 Is Regularly Associated with Accelerated Tumor Development in v-abl/myc-Induced Mouse Plasmacytomas. Genes Cancer (2010) 0.84
Prenatal and postnatal expression of glutathione transferase ζ 1 in human liver and the roles of haplotype and subject age in determining activity with dichloroacetate. Drug Metab Dispos (2011) 0.84
Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress. Am J Respir Cell Mol Biol (2014) 0.84
Elevated 12-month and lifetime prevalence and comorbidity rates of mood, anxiety, and alcohol use disorders in Chinese men who have sex with men. PLoS One (2013) 0.84
Selective induction of tumor cell apoptosis by a novel P450-mediated reactive oxygen species (ROS) inducer methyl 3-(4-nitrophenyl) propiolate. J Biol Chem (2013) 0.83
Effect of cigarette smoke exposure and structural modifications on the α-1 Antitrypsin interaction with caspases. Mol Med (2012) 0.83
Negative regulation of interferon-γ/STAT1 signaling through cell adhesion and cell density-dependent STAT1 dephosphorylation. Cell Signal (2011) 0.80
Protective immune response induced by co-immunization with the Trichinella spiralis recombinant Ts87 protein and a Ts87 DNA vaccine. Vet Parasitol (2013) 0.79
Monoclonal and bispecific antibodies as novel therapeutics. Arch Immunol Ther Exp (Warsz) (2006) 0.78
The role of Dlc1 isoform 2 in K-Ras2(G12D) induced thymic cancer. PLoS One (2012) 0.78
The effect of climate on migration: United States, 1995-2000. Soc Sci Res (2009) 0.78
Development of an LC/MS/MS method in order to determine arctigenin in rat plasma: its application to a pharmacokinetic study. Biomed Chromatogr (2013) 0.77
[Effect of different adjuvant formulations on the induced protection of mice immunized with recombinant protein ts87 of Trichinella spiralis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2007) 0.77
Absence of an immediate G1/S checkpoint in primary MEFs following gamma-irradiation identifies a novel checkpoint switch. Cell Cycle (2006) 0.76
StARD13(Dlc-2) RhoGap mediates ceramide activation of phosphatidylglycerolphosphate synthase and drug response in Chinese hamster ovary cells. Mol Biol Cell (2007) 0.75
Identification of two new single-nucleotide polymorphisms in FUT3 associated with the Lewis-null phenotype. Transfusion (2003) 0.75
Expression and Clinical Significance of Sushi Domain- Containing Protein 3 (SUSD3) and Insulin-like Growth Factor-I Receptor (IGF-IR) in Breast Cancer. Asian Pac J Cancer Prev (2015) 0.75
[Construction and expression of the Ts87 gene of Trichinella spiralis in Pichia pastoris]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2005) 0.75
Ferromagnetism of 3He films in the low-field limit. Phys Rev Lett (2002) 0.75
Advanced functional luminogens in the solid-state: general discussion. Faraday Discuss (2017) 0.75
From fullerene-mixed peroxide to open-cage oxafulleroid C(59)(O)(3)(OH)(2)(OO(t)()Bu)(2) embedded with furan and lactone motifs. Org Lett (2007) 0.75
Theory and Application of Microdialysis in Pharmacokinetic Studies. Curr Drug Metab (2015) 0.75
[Intracellular calcium ion concentration in the prostate smooth muscle cells of chronic abacterial prostatitis rat models and normal controls]. Zhonghua Nan Ke Xue (2011) 0.75
[Simultaneous determination of clevidipine butyrate and its metabolite clevidipine acid in dog blood by liquid chromatography-tandem mass spectrometry]. Yao Xue Xue Bao (2015) 0.75
[Study on the factors influencing the quality of life among patients with malignant lymphoma]. Zhonghua Liu Xing Bing Xue Za Zhi (2006) 0.75
Quantitation of catalpol in rat plasma by liquid chromatography/electrospray ionization tandem mass spectrometry and its pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.75
Metabolism of aildenafil in vivo in rats and in vitro in mouse, rat, dog, and human liver microsomes. Drug Test Anal (2013) 0.75
[Determination of tamsulosin in dog plasma by a high sensitive liquid chromatography-tandem mass spectrometric method]. Yao Xue Xue Bao (2007) 0.75
Quantitation of bentysrepinine (Y101) in rat plasma by liquid chromatography tandem mass spectrometry: application to pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci (2012) 0.75