Published in Br J Gen Pract on March 01, 2010
Recent advances in the utility and use of the General Practice Research Database as an example of a UK Primary Care Data resource. Ther Adv Drug Saf (2012) 4.71
Antidepressant use and risk of adverse outcomes in older people: population based cohort study. BMJ (2011) 3.74
Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000 people. Diabetes Care (2013) 2.96
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Fam Pract (2010) 2.93
Pioglitazone use and risk of bladder cancer: population based cohort study. BMJ (2016) 2.37
Cause-specific mortality in patients with severe psoriasis: a population-based cohort study in the U.K. Br J Dermatol (2010) 2.37
Completeness and usability of ethnicity data in UK-based primary care and hospital databases. J Public Health (Oxf) (2013) 2.30
Validating the 8 CPCSSN case definitions for chronic disease surveillance in a primary care database of electronic health records. Ann Fam Med (2014) 2.23
UK stroke incidence, mortality and cardiovascular risk management 1999-2008: time-trend analysis from the General Practice Research Database. BMJ Open (2011) 2.09
Identifying women with suspected ovarian cancer in primary care: derivation and validation of algorithm. BMJ (2011) 2.03
Attributable risk estimate of severe psoriasis on major cardiovascular events. Am J Med (2011) 1.94
Symptoms and risk factors to identify men with suspected cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2013) 1.84
Mortality and other important diabetes-related outcomes with insulin vs other antihyperglycemic therapies in type 2 diabetes. J Clin Endocrinol Metab (2013) 1.83
Symptoms and risk factors to identify women with suspected cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2013) 1.82
Variation in recorded child maltreatment concerns in UK primary care records: a cohort study using The Health Improvement Network (THIN) database. PLoS One (2012) 1.80
Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study. BMJ (2014) 1.79
Influenza infection and risk of acute myocardial infarction in England and Wales: a CALIBER self-controlled case series study. J Infect Dis (2012) 1.73
Comparison of cancer diagnostic intervals before and after implementation of NICE guidelines: analysis of data from the UK General Practice Research Database. Br J Cancer (2013) 1.71
Association between longer therapy with thiazolidinediones and risk of bladder cancer: a cohort study. J Natl Cancer Inst (2012) 1.69
Identifying patients with suspected colorectal cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2012) 1.67
Identifying patients with suspected pancreatic cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2012) 1.63
Identifying patients with suspected gastro-oesophageal cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2011) 1.63
Serum uric acid and the risk of respiratory disease: a population-based cohort study. Thorax (2014) 1.62
Increased risk of vascular disease associated with gout: a retrospective, matched cohort study in the UK clinical practice research datalink. Ann Rheum Dis (2014) 1.54
Risk of vascular events in patients with polymyalgia rheumatica. CMAJ (2014) 1.54
Exploiting the potential of large databases of electronic health records for research using rapid search algorithms and an intuitive query interface. J Am Med Inform Assoc (2013) 1.52
Academic impact of a public electronic health database: bibliometric analysis of studies using the general practice research database. PLoS One (2011) 1.51
Long-term health outcomes in a British cohort of breast, colorectal and prostate cancer survivors: a database study. Br J Cancer (2011) 1.44
Metformin and low levels of thyroid-stimulating hormone in patients with type 2 diabetes mellitus. CMAJ (2014) 1.44
The use of metformin and the incidence of lung cancer in patients with type 2 diabetes. Diabetes Care (2012) 1.42
Identifying patients with suspected renal tract cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2012) 1.42
Coding, recording and incidence of different forms of coronary heart disease in primary care. PLoS One (2012) 1.39
The risk of pancreatic cancer in symptomatic patients in primary care: a large case-control study using electronic records. Br J Cancer (2012) 1.38
Identifying patients with suspected lung cancer in primary care: derivation and validation of an algorithm. Br J Gen Pract (2011) 1.35
The incidence of eating disorders in the UK in 2000-2009: findings from the General Practice Research Database. BMJ Open (2013) 1.34
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis. Gut (2013) 1.26
Features of childhood cancer in primary care: a population-based nested case-control study. Br J Cancer (2012) 1.23
Cancer screening and preventative care among long-term cancer survivors in the United Kingdom. Br J Cancer (2010) 1.22
Risk of childhood cancer with symptoms in primary care: a population-based case-control study. Br J Gen Pract (2013) 1.20
The risk of oesophago-gastric cancer in symptomatic patients in primary care: a large case-control study using electronic records. Br J Cancer (2012) 1.18
Risk of fracture after bariatric surgery in the United Kingdom: population based, retrospective cohort study. BMJ (2012) 1.17
Comorbidities in patients with gout prior to and following diagnosis: case-control study. Ann Rheum Dis (2014) 1.17
Prevalence and treatment patterns of psoriatic arthritis in the UK. Rheumatology (Oxford) (2012) 1.15
Trends in depression and antidepressant prescribing in children and adolescents: a cohort study in The Health Improvement Network (THIN). PLoS One (2012) 1.14
Is cancer associated with polymyalgia rheumatica? A cohort study in the General Practice Research Database. Ann Rheum Dis (2013) 1.13
Population based study of 12 autoimmune diseases in Sardinia, Italy: prevalence and comorbidity. PLoS One (2012) 1.12
From patient care to research: a validation study examining the factors contributing to data quality in a primary care electronic medical record database. BMC Fam Pract (2015) 1.11
Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink. BMC Cardiovasc Disord (2014) 1.10
Heterogeneous associations between smoking and a wide range of initial presentations of cardiovascular disease in 1937360 people in England: lifetime risks and implications for risk prediction. Int J Epidemiol (2014) 1.09
Clinical features of kidney cancer in primary care: a case-control study using primary care records. Br J Gen Pract (2013) 1.09
A retrospective cohort study assessing patient characteristics and the incidence of cardiovascular disease using linked routine primary and secondary care data. BMJ Open (2012) 1.08
Ischaemic cardiac events and use of strontium ranelate in postmenopausal osteoporosis: a nested case-control study in the CPRD. Osteoporos Int (2013) 1.06
Validation of diabetes mellitus and hypertension diagnosis in computerized medical records in primary health care. BMC Med Res Methodol (2011) 1.06
Defining upper gastrointestinal bleeding from linked primary and secondary care data and the effect on occurrence and 28 day mortality. BMC Health Serv Res (2012) 1.05
Risk of uterine cancer in symptomatic women in primary care: case-control study using electronic records. Br J Gen Pract (2013) 1.05
Implications of comorbidity for primary care costs in the UK: a retrospective observational study. Br J Gen Pract (2013) 1.04
Validity of diagnoses in the general practice research database. Br J Gen Pract (2011) 1.03
Physicians' prescribing preferences were a potential instrument for patients' actual prescriptions of antidepressants. J Clin Epidemiol (2013) 1.02
Much more medicine for the oldest old: trends in UK electronic clinical records. Age Ageing (2014) 0.98
Psoriasis and the Risk of Major Cardiovascular Events: Cohort Study Using the Clinical Practice Research Datalink. J Invest Dermatol (2015) 0.98
Bisphosphonates and risk of upper gastrointestinal cancer--a case control study using the General Practice Research Database (GPRD). PLoS One (2012) 0.96
Childhood nonspecific abdominal pain in family practice: incidence, associated factors, and management. Ann Fam Med (2011) 0.96
Delay in treatment intensification increases the risks of cardiovascular events in patients with type 2 diabetes. Cardiovasc Diabetol (2015) 0.95
Case validation in research using large databases. Br J Gen Pract (2010) 0.94
Distinguishing incident and prevalent diabetes in an electronic medical records database. Pharmacoepidemiol Drug Saf (2013) 0.93
Addressing the deficiencies in the evidence-base for primary practice in regional Australia - sentinel practices data sourcing (SPDS) project: a pilot study. BMC Fam Pract (2013) 0.93
Risk of breast cancer in symptomatic women in primary care: a case-control study using electronic records. Br J Gen Pract (2014) 0.93
Improvement in the management of gout is vital and overdue: an audit from a UK primary care medical practice. BMC Fam Pract (2013) 0.93
Adverse events recorded in English primary care: observational study using the General Practice Research Database. Br J Gen Pract (2013) 0.93
What does validation of cases in electronic record databases mean? The potential contribution of free text. Pharmacoepidemiol Drug Saf (2011) 0.92
Clinical management following self-harm in a UK-wide primary care cohort. J Affect Disord (2016) 0.91
Quantifying the risk of Hodgkin lymphoma in symptomatic primary care patients aged ≥40 years: a case-control study using electronic records. Br J Gen Pract (2015) 0.91
Helping everyone do better: a call for validation studies of routinely recorded health data. Clin Epidemiol (2016) 0.91
Risk of pneumonia in patients taking statins: population-based nested case-control study. Br J Gen Pract (2011) 0.90
Clinical inertia with regard to intensifying therapy in people with type 2 diabetes treated with basal insulin. Diabetes Obes Metab (2016) 0.89
Diagnostic intervals and its association with breast, prostate, lung and colorectal cancer survival in England: historical cohort study using the Clinical Practice Research Datalink. PLoS One (2015) 0.89
Using data from patient interactions in primary care for population level chronic disease surveillance: The Sentinel Practices Data Sourcing (SPDS) project. BMC Public Health (2014) 0.89
Use of Acid Suppression Medication is Associated With Risk for C. difficile Infection in Infants and Children: A Population-based Study. Clin Infect Dis (2015) 0.89
Benchmarking the burden of 100 diseases: results of a nationwide representative survey within general practices. BMJ Open (2011) 0.88
The prevalence and incidence, resource use and financial costs of treating people with attention deficit/hyperactivity disorder (ADHD) in the United Kingdom (1998 to 2010). Child Adolesc Psychiatry Ment Health (2013) 0.88
Diabetes, use of antidiabetic drugs, and the risk of glioma. Neuro Oncol (2015) 0.88
The freetext matching algorithm: a computer program to extract diagnoses and causes of death from unstructured text in electronic health records. BMC Med Inform Decis Mak (2012) 0.87
Calculating Total Health Service Utilisation and Costs from Routinely Collected Electronic Health Records Using the Example of Patients with Irritable Bowel Syndrome Before and After Their First Gastroenterology Appointment. Pharmacoeconomics (2016) 0.87
Palliative care among heart failure patients in primary care: a comparison to cancer patients using English family practice data. PLoS One (2014) 0.86
Recent HbA1c values and mortality risk in type 2 diabetes. population-based case-control study. PLoS One (2013) 0.86
Proactive and integrated primary care for frail older people: design and methodological challenges of the Utrecht primary care PROactive frailty intervention trial (U-PROFIT). BMC Geriatr (2012) 0.86
Quality of care for chronic diseases in a British cohort of long-term cancer survivors. Ann Fam Med (2010) 0.86
Impact of clinical trial findings on Bell's palsy management in general practice in the UK 2001-2012: interrupted time series regression analysis. BMJ Open (2013) 0.85
Quantifying the risk of multiple myeloma from symptoms reported in primary care patients: a large case-control study using electronic records. Br J Gen Pract (2015) 0.85
Mortality and medical care after bereavement: a general practice cohort study. PLoS One (2013) 0.85
Identifying influenza-like illness presentation from unstructured general practice clinical narrative using a text classifier rule-based expert system versus a clinical expert. BMC Med Inform Decis Mak (2015) 0.85
Accuracy of pneumonia hospital admissions in a primary care electronic medical record database. Pharmacoepidemiol Drug Saf (2012) 0.85
Accuracy of Electronic Health Record Data for Identifying Stroke Cases in Large-Scale Epidemiological Studies: A Systematic Review from the UK Biobank Stroke Outcomes Group. PLoS One (2015) 0.84
A case-control study comparing the incidence of early symptoms in pancreatic and biliary tract cancer. BMJ Open (2014) 0.84
Elevated risk of clinical fractures and associated risk factors in patients with systemic lupus erythematosus versus matched controls: a population-based study in the United Kingdom. Osteoporos Int (2013) 0.84
Identifying patients with undetected pancreatic cancer in primary care: an independent and external validation of QCancer(®) (Pancreas). Br J Gen Pract (2013) 0.83
Validation of information recorded on general practitioner based computerised data resource in the United Kingdom. BMJ (1991) 17.91
The UK General Practice Research Database. Lancet (1997) 10.62
Use of the UK General Practice Research Database for pharmacoepidemiology. Br J Clin Pharmacol (1998) 7.41
The General Practice Research Database: quality of morbidity data. Popul Trends (1997) 7.07
Accuracy of diagnosis of psychosis on general practice computer system. BMJ (1993) 4.88
Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: population based case-control study. BMJ (1999) 4.21
Systematic review of scope and quality of electronic patient record data in primary care. BMJ (2003) 4.02
Lower risk of thromboembolic cardiovascular events with naproxen among patients with rheumatoid arthritis. Arch Intern Med (2002) 3.24
Recombinant hepatitis B vaccine and the risk of multiple sclerosis: a prospective study. Neurology (2004) 3.21
Measuring disease prevalence: a comparison of musculoskeletal disease using four general practice consultation databases. Br J Gen Pract (2007) 3.16
Validation of the diagnosis of venous thromboembolism in general practice database studies. Br J Clin Pharmacol (2000) 3.05
Quality of morbidity coding in general practice computerized medical records: a systematic review. Fam Pract (2004) 2.92
Use of the General Practice Research Database (GPRD) for respiratory epidemiology: a comparison with the 4th Morbidity Survey in General Practice (MSGP4). Thorax (1999) 2.91
Registry evaluation methods: a review and case study. Epidemiol Rev (1980) 2.45
How accurate are diagnoses for rheumatoid arthritis and juvenile idiopathic arthritis in the general practice research database? Arthritis Rheum (2008) 2.27
Validation of the diagnosis of autism in general practitioner records. BMC Public Health (2004) 2.22
Venous leg ulcer: incidence and prevalence in the elderly. J Am Acad Dermatol (2002) 2.13
Validity and completeness of the General Practice Research Database for studies of inflammatory bowel disease. Pharmacoepidemiol Drug Saf (2002) 2.12
Incidence and risk factors for psoriasis in the general population. Arch Dermatol (2007) 2.12
Acute and clinically relevant drug-induced liver injury: a population based case-control study. Br J Clin Pharmacol (2004) 1.95
Incidence of chronic atrial fibrillation in general practice and its treatment pattern. J Clin Epidemiol (2002) 1.92
Nonsteroidal anti-inflammatory drugs and risk of ARF in the general population. Am J Kidney Dis (2005) 1.89
Developing a large electronic primary care database (Doctors' Independent Network) for research. Int J Med Inform (2004) 1.88
Determining the predictive value of Read/OXMIS codes to identify incident acute myocardial infarction in the General Practice Research Database. Pharmacoepidemiol Drug Saf (2008) 1.85
Antidepressant drugs and suicide. J Clin Psychopharmacol (1992) 1.80
Validation of general practitioner-diagnosed COPD in the UK General Practice Research Database. Eur J Epidemiol (2001) 1.78
The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results. Pharmacoepidemiol Drug Saf (2000) 1.70
Relation of childhood gastrointestinal disorders to autism: nested case-control study using data from the UK General Practice Research Database. BMJ (2002) 1.69
The demand for eating disorder care. An epidemiological study using the general practice research database. Br J Psychiatry (1996) 1.63
Agreement between GPRD smoking data: a survey of general practitioners and a population-based survey. Pharmacoepidemiol Drug Saf (2004) 1.61
Investigation of the temporal association of Guillain-Barre syndrome with influenza vaccine and influenzalike illness using the United Kingdom General Practice Research Database. Am J Epidemiol (2008) 1.58
The incidence and prevalence of pressure ulcers among elderly patients in general medical practice. Ann Epidemiol (2002) 1.57
The utility of the general practice research database to examine selected congenital heart defects: a validation study. Pharmacoepidemiol Drug Saf (2007) 1.52
Risk of ventricular arrhythmias associated with nonsedating antihistamine drugs. Br J Clin Pharmacol (1999) 1.49
Incidence and natural history of Paget's disease of bone in England and Wales. J Bone Miner Res (2002) 1.37
Hormone replacement therapy and incidence of acute myocardial infarction. A population-based nested case-control study. Circulation (2000) 1.35
Association between dementia and infectious disease: evidence from a case-control study. Alzheimer Dis Assoc Disord (2005) 1.29
Recent use of oral contraceptives and the risk of multiple sclerosis. Arch Neurol (2005) 1.27
A cohort study on the risk of acute liver injury among users of ketoconazole and other antifungal drugs. Br J Clin Pharmacol (1999) 1.26
Risk of cataract among users of intranasal corticosteroids. J Allergy Clin Immunol (2000) 1.15
Appendectomy protects against ulcerative colitis. Epidemiology (1998) 1.15
The risk of acute pancreatitis associated with acid-suppressing drugs. Br J Clin Pharmacol (2000) 1.13
Diagnostic codes for sudden cardiac death and ventricular arrhythmia functioned poorly to identify outpatient events in EPIC's General Practice Research Database. Pharmacoepidemiol Drug Saf (2008) 1.09
A comparison of the recording of 30 common childhood conditions in the Doctor's Independent Network and General Practice Research Databases. Health Stat Q (2004) 1.09
The use of general practice consultation databases in rheumatology research. Rheumatology (Oxford) (2005) 1.05
Respiratory medications and the risk of cardiac arrhythmias. Epidemiology (2005) 1.05
A comparison of trends in problematic drug misuse from two reporting systems. J Public Health Med (2000) 1.02
Oral contraceptives and venous thromboembolic disease. Analyses of the UK General Practice Research Database and the UK Mediplus database. Hum Reprod Update (2000) 1.00
Is hormone replacement therapy associated with an increased risk of irritable bowel syndrome? Maturitas (2003) 1.00
Implications of the problem orientated medical record (POMR) for research using electronic GP databases: a comparison of the Doctors Independent Network Database (DIN) and the General Practice Research Database (GPRD). BMC Fam Pract (2003) 0.98
Risk of acute liver injury in patients with diabetes. Pharmacotherapy (2002) 0.95
Evaluation of the General Practice Research Database congenital heart defects prevalence: comparison to United Kingdom national systems. Birth Defects Res A Clin Mol Teratol (2007) 0.90
Validation of neural tube defects in the full featured--general practice research database. Pharmacoepidemiol Drug Saf (2008) 0.90
BioJava: an open-source framework for bioinformatics in 2012. Bioinformatics (2012) 2.94
Adaptation and validation of the Charlson Index for Read/OXMIS coded databases. BMC Fam Pract (2010) 2.93
Pre-calculated protein structure alignments at the RCSB PDB website. Bioinformatics (2010) 2.28
Views of primary care physicians and oncologists on cancer follow-up initiatives in primary care: an online survey. J Cancer Surviv (2010) 1.33
Primary health and supportive care needs of long-term cancer survivors: a questionnaire survey. J Clin Oncol (2011) 1.29
Integration of open access literature into the RCSB Protein Data Bank using BioLit. BMC Bioinformatics (2010) 1.22
Trendspotting in the Protein Data Bank. FEBS Lett (2013) 1.19
Complexity and simplicity of ligand-macromolecule interactions: the energy landscape perspective. Curr Opin Struct Biol (2002) 1.18
Economic and quality-of-life impact of seasonal allergic conjunctivitis in Oxfordshire. Ophthalmic Epidemiol (2004) 1.17
Primary care consultation behaviours of long-term, adult survivors of cancer in the UK. Br J Gen Pract (2011) 1.15
Long-term survivors of adult cancers and uptake of primary health services: a systematic review. Eur J Cancer (2007) 1.15
Simulating disorder-order transitions in molecular recognition of unstructured proteins: where folding meets binding. Proc Natl Acad Sci U S A (2003) 1.06
Experiences of follow-up after treatment in patients with prostate cancer: a qualitative study. BJU Int (2010) 1.02
Relative impact of clinical evidence and over-the-counter prescribing on topical antibiotic use for acute infective conjunctivitis. Br J Gen Pract (2009) 0.99
Design, synthesis, and biological evaluation of novel human 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP) substrates. Bioorg Med Chem Lett (2005) 0.96
Consulting and prescribing behaviour for anxiety and depression in long-term survivors of cancer in the UK. Eur J Cancer (2010) 0.93
Views of health professionals on the role of primary care in the follow-up of men with prostate cancer. Fam Pract (2011) 0.89
Defining cancer survivorship: a more transparent approach is needed. J Cancer Surviv (2011) 0.89
Quality of care for chronic diseases in a British cohort of long-term cancer survivors. Ann Fam Med (2010) 0.86
Optimal loading dose of warfarin for the initiation of oral anticoagulation. Cochrane Database Syst Rev (2012) 0.86
Computational detection of the binding-site hot spot at the remodeled human growth hormone-receptor interface. Proteins (2003) 0.85
Educational interventions for primary healthcare professionals to promote the early diagnosis of cancer: a systematic review. Educ Prim Care (2013) 0.83
Cancer survivorship: the impact on primary care. Br J Gen Pract (2011) 0.82
A qualitative study exploring the experience of the partners of cancer survivors and their views on the role of primary care. Support Care Cancer (2012) 0.79
Hierarchy of simulation models in predicting structure and energetics of the Src SH2 domain binding to tyrosyl phosphopeptides. J Med Chem (2002) 0.78
Quality assurance for the query and distribution systems of the RCSB Protein Data Bank. Database (Oxford) (2011) 0.77
Colorectal cancer. Secondary care data may mislead. BMJ (2010) 0.75
What is the value of routine follow-up after diagnosis and treatment of cancer? Br J Gen Pract (2009) 0.75
Implementing evidence in practice: do action lists work? Educ Prim Care (2012) 0.75
Microscopic colitis in primary care. BMJ (2010) 0.75