Published in J Biomed Opt on March 09, 2010
Point-of-care pathology with miniature microscopes. Anal Cell Pathol (Amst) (2011) 1.11
Current and future clinical applications for optical imaging of cancer: from intraoperative surgical guidance to cancer screening. Semin Oncol (2011) 1.07
ABCG2 transporter inhibitor restores the sensitivity of triple negative breast cancer cells to aminolevulinic acid-mediated photodynamic therapy. Sci Rep (2015) 0.84
Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay. Free Radic Biol Med (2011) 0.81
Her2 oncogene transformation enhances 5-aminolevulinic acid-mediated protoporphyrin IX production and photodynamic therapy response. Oncotarget (2016) 0.75
MDA-MB-435 cells are derived from M14 melanoma cells--a loss for breast cancer, but a boon for melanoma research. Breast Cancer Res Treat (2006) 4.04
MDA-MB-435 and M14 cell lines: identical but not M14 melanoma? Cancer Res (2009) 3.74
Tumor paint: a chlorotoxin:Cy5.5 bioconjugate for intraoperative visualization of cancer foci. Cancer Res (2007) 3.25
Predictors of re-excision among women undergoing breast-conserving surgery for cancer. Ann Surg Oncol (2008) 2.14
Predictors of surgical margin status in breast-conserving surgery within a breast screening program. Ann Surg Oncol (2008) 1.93
Role for intraoperative margin assessment in patients undergoing breast-conserving surgery. Ann Surg Oncol (2007) 1.92
The consequence of multiple re-excisions to obtain clear lumpectomy margins in breast cancer patients. Ann Surg Oncol (2005) 1.87
ALA and its clinical impact, from bench to bedside. Photochem Photobiol Sci (2007) 1.54
Influence of frozen-section analysis of sentinel lymph node and lumpectomy margin status on reoperation rates in patients undergoing breast-conservation therapy. J Am Coll Surg (2007) 1.48
Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. Gastrointest Endosc (1999) 1.45
Factors correlating with reexcision after breast-conserving therapy. Eur J Surg Oncol (2008) 1.37
The influence of additional surgical margins on the total specimen volume excised and the reoperative rate after breast-conserving surgery. Am J Surg (2006) 1.22
A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis. Int J Cancer (2002) 1.18
Factors affecting successful breast conservation for ductal carcinoma in situ. Ann Surg Oncol (2007) 1.18
Optically tunable nanoparticle contrast agents for early cancer detection: model-based analysis of gold nanoshells. J Biomed Opt (2006) 1.14
Molecular fluorescence excitation-emission matrices relevant to tissue spectroscopy. Photochem Photobiol (2003) 1.12
Influence of breast cancer margin assessment method on the rates of positive margins and residual carcinoma. Am J Surg (2006) 1.09
Protoporphyrin IX level correlates with number of mitochondria, but increase in production correlates with tumor cell size. Photochem Photobiol (2007) 1.08
5-Aminolevulinic acid derivatives in photomedicine: Characteristics, application and perspectives. Photochem Photobiol (2007) 1.07
Metabolic characterization of tumor cell-specific protoporphyrin IX accumulation after exposure to 5-aminolevulinic acid in human colonic cells. Photochem Photobiol (2002) 1.03
Preliminary evaluation of two fluorescence imaging methods for the detection and the delineation of basal cell carcinomas of the skin. Lasers Surg Med (2000) 0.98
Heme biosynthesis in human breast cancer--mimetic "in vitro" studies and some heme enzymic activity levels. Int J Biochem (1990) 0.97
ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells. Lasers Surg Med (2009) 0.96
Protoporphyrin IX occurs naturally in colorectal cancers and their metastases. Cancer Res (2001) 0.93
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines. J Photochem Photobiol B (2006) 0.93
Can autofluorescence demarcate basal cell carcinoma from normal skin? A comparison with protoporphyrin IX fluorescence. Acta Derm Venereol (2001) 0.92
A multimodal contrast agent for preoperative MR Imaging and intraoperative tumor margin delineation. Technol Cancer Res Treat (2006) 0.91
Photodynamic diagnosis of breast tumours after oral application of aminolevulinic acid. Br J Cancer (2001) 0.90
Molecular optical imaging of therapeutic targets of cancer. Adv Cancer Res (2007) 0.88
Noninvasive measurement of aminolevulinic acid-induced protoporphyrin IX fluorescence allowing detection of murine glioma in vivo. J Biomed Opt (2009) 0.87
Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity. Am J Surg (1996) 0.86
Photodynamic detection of diseased axillary sentinel lymph node after oral application of aminolevulinic acid in patients with breast cancer. Br J Cancer (2004) 0.86
In vitro study of biosynthesis of protoporphyrin IX induced by delta-aminolevulinic acid in normal and cancerous cells of the human cervix. Arch Med Res (1999) 0.86
Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation. Br J Cancer (2005) 0.84
Repetitive photodynamic therapy of malignant brain tumors. J Environ Pathol Toxicol Oncol (2006) 0.84
Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. J Photochem Photobiol B (2006) 0.84
Variant estrogen receptor alpha mRNAs in human breast cancer specimens. Int J Cancer (2000) 0.82
Relation between intracellular location and photodynamic efficacy of 5-aminolevulinic acid-induced protoporphyrin IX in vitro. Comparison between human glioblastoma cells and other cancer cell lines. Photochem Photobiol Sci (2006) 0.82
Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity. Oncogene (2004) 0.80
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells. J Environ Pathol Toxicol Oncol (2007) 0.79
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor. Respiration (2002) 0.79
Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. J Urol (2001) 0.78
Response to ALA-based PDT in an immortalised normal breast cell line and its counterpart transformed with the Ras oncogene. Photochem Photobiol Sci (2007) 0.78
Endogenous production of protoporphyrin IX induced by 5-aminolevulinic acid in leukemia cells. Acta Pharmacol Sin (2001) 0.78
Kinetic fluorescence studies of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation in basal cell carcinomas. J Photochem Photobiol B (1999) 0.78
Breast-conservation treatment outcomes: a community hospital's experience. Breast J (2008) 0.77
Fluorescence diagnostics and kinetic studies in the head and neck region utilizing low-dose delta-aminolevulinic acid sensitization. Cancer Lett (1999) 0.77
Photodynamic effects of 5-aminolevulinic acid and its hexylester on several cell lines. Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai) (2003) 0.77
Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system. Chem Biol (2005) 0.76
In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia. Proc Natl Acad Sci U S A (2007) 4.53
Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms. Appl Opt (2006) 3.17
Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues. Cancer Res (2005) 2.28
Metabolic mapping of MCF10A human breast cells via multiphoton fluorescence lifetime imaging of the coenzyme NADH. Cancer Res (2005) 2.15
In vivo multiphoton fluorescence lifetime imaging of protein-bound and free nicotinamide adenine dinucleotide in normal and precancerous epithelia. J Biomed Opt (2007) 2.09
Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis. Appl Opt (2006) 1.64
Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo. Cancer Res (2009) 1.47
Diagnosis of breast cancer using diffuse reflectance spectroscopy: Comparison of a Monte Carlo versus partial least squares analysis based feature extraction technique. Lasers Surg Med (2006) 1.46
Investigation of fiber-optic probe designs for optical spectroscopic diagnosis of epithelial pre-cancers. Lasers Surg Med (2004) 1.46
Advances in quantitative UV-visible spectroscopy for clinical and pre-clinical application in cancer. Curr Opin Biotechnol (2009) 1.44
Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins. Opt Express (2010) 1.43
Real-time, high velocity-resolution color Doppler optical coherence tomography. Opt Lett (2002) 1.37
Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003). IEEE Trans Biomed Eng (2003) 1.35
Rapid noninvasive optical imaging of tissue composition in breast tumor margins. Am J Surg (2009) 1.33
Optical redox ratio differentiates breast cancer cell lines based on estrogen receptor status. Cancer Res (2010) 1.28
Quantitative physiology of the precancerous cervix in vivo through optical spectroscopy. Neoplasia (2009) 1.28
Use of a multiseparation fiber optic probe for the optical diagnosis of breast cancer. J Biomed Opt (2005) 1.28
Frequency estimation precision in Doppler optical coherence tomography using the Cramer-Rao lower bound. Opt Express (2005) 1.26
Diagnosis of breast cancer using fluorescence and diffuse reflectance spectroscopy: a Monte-Carlo-model-based approach. J Biomed Opt (2008) 1.26
A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo. IEEE Trans Biomed Eng (2009) 1.24
Experimental validation of Monte Carlo modeling of fluorescence in tissues in the UV-visible spectrum. J Biomed Opt (2003) 1.20
Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues. Ann Surg Oncol (2004) 1.19
Molecular contrast in optical coherence tomography by use of a pump-probe technique. Opt Lett (2003) 1.19
Compact instrument for fluorescence image-guided surgery. J Biomed Opt (2010) 1.18
Monte-Carlo-based model for the extraction of intrinsic fluorescence from turbid media. J Biomed Opt (2008) 1.15
Doppler flow imaging of cytoplasmic streaming using spectral domain phase microscopy. J Biomed Opt (2006) 1.15
Experimental proof of the feasibility of using an angled fiber-optic probe for depth-sensitive fluorescence spectroscopy of turbid media. Opt Lett (2004) 1.15
Effect of fiber optic probe geometry on depth-resolved fluorescence measurements from epithelial tissues: a Monte Carlo simulation. J Biomed Opt (2003) 1.12
Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines. Breast Cancer Res Treat (2011) 1.12
Dual-mode laparoscopic fluorescence image-guided surgery using a single camera. Biomed Opt Express (2012) 1.10
Scaling method for fast Monte Carlo simulation of diffuse reflectance spectra from multilayered turbid media. J Opt Soc Am A Opt Image Sci Vis (2007) 1.09
Autofluorescence spectroscopy of normal and malignant human breast cell lines. Photochem Photobiol (2003) 1.09
Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast. Breast Cancer Res (2010) 1.08
Diffuse reflectance spectroscopy with a self-calibrating fiber optic probe. Opt Lett (2008) 1.07
The type III TGF-beta receptor signals through both Smad3 and the p38 MAP kinase pathways to contribute to inhibition of cell proliferation. Carcinogenesis (2007) 1.06
Multiphoton microscopy with near infrared contrast agents. J Biomed Opt (2010) 1.05
A strategy for quantitative spectral imaging of tissue absorption and scattering using light emitting diodes and photodiodes. Opt Express (2009) 1.05
Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast. PLoS One (2012) 1.04
Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo. J Biomed Opt (2009) 1.03
Sequential estimation of optical properties of a two-layered epithelial tissue model from depth-resolved ultraviolet-visible diffuse reflectance spectra. Appl Opt (2006) 1.03
Monitoring of receptor dimerization using plasmonic coupling of gold nanoparticles. ACS Nano (2011) 1.03
Relationship between collagen autofluorescence of the human cervix and menopausal status. Photochem Photobiol (2003) 1.03
Optimal methods for fluorescence and diffuse reflectance measurements of tissue biopsy samples. Lasers Surg Med (2002) 1.02
Real-time in vivo color Doppler optical coherence tomography. J Biomed Opt (2002) 1.02
Fluorescence spectroscopy: an adjunct diagnostic tool to image-guided core needle biopsy of the breast. IEEE Trans Biomed Eng (2009) 1.02
Instrument independent diffuse reflectance spectroscopy. J Biomed Opt (2011) 1.02
A small animal Raman instrument for rapid, wide-area, spectroscopic imaging. Proc Natl Acad Sci U S A (2013) 1.02
Optimization of a widefield structured illumination microscope for non-destructive assessment and quantification of nuclear features in tumor margins of a primary mouse model of sarcoma. PLoS One (2013) 1.01
Cost-effective diffuse reflectance spectroscopy device for quantifying tissue absorption and scattering in vivo. J Biomed Opt (2009) 1.01
Application of the T-matrix method to determine the structure of spheroidal cell nuclei with angle-resolved light scattering. Opt Lett (2008) 1.00
Comparison of a physical model and principal component analysis for the diagnosis of epithelial neoplasias in vivo using diffuse reflectance spectroscopy. Opt Express (2007) 1.00
CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. Cancer Epidemiol Biomarkers Prev (2009) 0.99
Intraoperative fluorescence imaging of peripheral and central nerves through a myelin-selective contrast agent. Mol Imaging Biol (2012) 0.96
Combined physical and chemical immobilization of glucose oxidase in alginate microspheres improves stability of encapsulation and activity. Bioconjug Chem (2005) 0.95
Wavelength optimization for quantitative spectral imaging of breast tumor margins. PLoS One (2013) 0.94
A diffuse reflectance spectral imaging system for tumor margin assessment using custom annular photodiode arrays. Biomed Opt Express (2012) 0.93
Visualization of subsurface blood vessels by color Doppler optical coherence tomography in rats: before and after hemostatic therapy. Gastrointest Endosc (2002) 0.93
Ultrafast optical pulse delivery with fibers for nonlinear microscopy. Microsc Res Tech (2008) 0.92
Model based and empirical spectral analysis for the diagnosis of breast cancer. Opt Express (2008) 0.92
Stabilization of glucose oxidase in alginate microspheres with photoreactive diazoresin nanofilm coatings. Biotechnol Bioeng (2005) 0.92
PELP1: a review of PELP1 interactions, signaling, and biology. Mol Cell Endocrinol (2013) 0.92
Mammary gland specific expression of Brk/PTK6 promotes delayed involution and tumor formation associated with activation of p38 MAPK. Breast Cancer Res (2011) 0.90
Whole-body, real-time preclinical imaging of quantum dot fluorescence with time-gated detection. J Biomed Opt (2010) 0.89
Multiphoton redox ratio imaging for metabolic monitoring in vivo. Methods Mol Biol (2010) 0.88
Visible light optical spectroscopy is sensitive to neovascularization in the dysplastic cervix. J Biomed Opt (2010) 0.88
Noninvasive monitoring of tissue hemoglobin using UV-VIS diffuse reflectance spectroscopy: a pilot study. Opt Express (2009) 0.88
Effect of optical clearing agents on the in vivo optical properties of squamous epithelial tissue. Lasers Surg Med (2006) 0.87
Rapid ratiometric determination of hemoglobin concentration using UV-VIS diffuse reflectance at isosbestic wavelengths. Opt Express (2010) 0.87
Experimental validation of an inverse fluorescence Monte Carlo model to extract concentrations of metabolically relevant fluorophores from turbid phantoms and a murine tumor model. J Biomed Opt (2012) 0.86
Relationship between depth of a target in a turbid medium and fluorescence measured by a variable-aperture method. Opt Lett (2002) 0.86
Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins. PLoS One (2013) 0.86
Radiation induces aerobic glycolysis through reactive oxygen species. Radiother Oncol (2013) 0.85
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system. PLoS One (2012) 0.85
Towards a field-compatible optical spectroscopic device for cervical cancer screening in resource-limited settings: effects of calibration and pressure. Opt Express (2011) 0.85
ESR1 promoter hypermethylation does not predict atypia in RPFNA nor persistent atypia after 12 months tamoxifen chemoprevention. Cancer Epidemiol Biomarkers Prev (2008) 0.85
Interferometric second harmonic generation microscopy. Opt Express (2004) 0.85
Feasibility of near-infrared diffuse optical spectroscopy on patients undergoing imageguided core-needle biopsy. Opt Express (2007) 0.84
Electromagnetic spectroscopy of normal breast tissue specimens obtained from reduction surgeries: comparison of optical and microwave properties. IEEE Trans Biomed Eng (2008) 0.84
Autoconfocal transmission microscopy based on two-photon-induced photocurrent of Si photodiodes. Opt Lett (2010) 0.83
Delivery rate affects uptake of a fluorescent glucose analog in murine metastatic breast cancer. PLoS One (2013) 0.82
Polyelectrolyte microshells as carriers for fluorescent sensors: loading and sensing properties of a ruthenium-based oxygen indicator. J Nanosci Nanotechnol (2003) 0.82
Introduction to neutron stimulated emission computed tomography. Phys Med Biol (2006) 0.81
Two-photon optical properties of near-infrared dyes at 1.55 μm excitation. J Phys Chem B (2011) 0.81
Endoscopically compatible near-infrared photon migration probe. Opt Lett (2004) 0.80
Use of genetic algorithms to optimize fiber optic probe design for the extraction of tissue optical properties. IEEE Trans Biomed Eng (2007) 0.80
Steady-state fluorescence imaging of neoplasia. Methods Enzymol (2003) 0.78
Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero. Proc Natl Acad Sci U S A (2003) 0.77
Self-referenced Doppler optical coherence tomography. Opt Lett (2002) 0.77
Measuring tumor cycling hypoxia and angiogenesis using a side-firing fiber optic probe. J Biophotonics (2012) 0.76
Visualization of morphological and molecular features associated with chronic ischemia in bioengineered human skin. Microsc Microanal (2010) 0.75
All-near-infrared multiphoton microscopy interrogates intact tissues at deeper imaging depths than conventional single- and two-photon near-infrared excitation microscopes. J Biomed Opt (2013) 0.75
Neutron-stimulated emission computed tomography of a multi-element phantom. Phys Med Biol (2008) 0.75
Phase-referenced Doppler optical coherence tomography in scattering media. Opt Lett (2005) 0.75