Published in Cancer Res on May 11, 2010
Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer. Cancer Res (2013) 1.50
Quantitative optical imaging of primary tumor organoid metabolism predicts drug response in breast cancer. Cancer Res (2014) 1.13
SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents. Cell Metab (2015) 1.06
Characterization of metabolic changes associated with the functional development of 3D engineered tissues by non-invasive, dynamic measurement of individual cell redox ratios. Biomaterials (2012) 1.05
Ex vivo optical metabolic measurements from cultured tissue reflect in vivo tissue status. J Biomed Opt (2012) 0.99
Optical imaging of metabolism in HER2 overexpressing breast cancer cells. Biomed Opt Express (2011) 0.98
Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells. BMC Genomics (2014) 0.94
Breast cancer redox heterogeneity detectable with chemical exchange saturation transfer (CEST) MRI. Mol Imaging Biol (2014) 0.93
Optical metabolic imaging of treatment response in human head and neck squamous cell carcinoma. PLoS One (2014) 0.86
Compact point-detection fluorescence spectroscopy system for quantifying intrinsic fluorescence redox ratio in brain cancer diagnostics. J Biomed Opt (2011) 0.83
High-throughput measurements of the optical redox ratio using a commercial microplate reader. J Biomed Opt (2015) 0.79
Monitoring of tumor response to Cisplatin using optical spectroscopy. Transl Oncol (2014) 0.79
Cytoplasmic PELP1 and ERRgamma protect human mammary epithelial cells from Tam-induced cell death. PLoS One (2015) 0.79
Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism. Biomed Opt Express (2016) 0.78
In Vivo Visualization of Stromal Macrophages via label-free FLIM-based metabolite imaging. Sci Rep (2016) 0.78
Head and neck squamous cell carcinoma in pregnant women. Head Neck (2012) 0.78
Detection of urinary bladder cancer cells using redox ratio and double excitation wavelengths autofluorescence. Biomed Opt Express (2015) 0.78
Quantification of the Metabolic State in Cell-Model of Parkinson's Disease by Fluorescence Lifetime Imaging Microscopy. Sci Rep (2016) 0.78
In Vivo Autofluorescence Imaging of Tumor Heterogeneity in Response to Treatment. Neoplasia (2015) 0.78
Correlating two-photon excited fluorescence imaging of breast cancer cellular redox state with seahorse flux analysis of normalized cellular oxygen consumption. J Biomed Opt (2016) 0.77
Optical imaging of mitochondrial redox state in rodent models with 3-iodothyronamine. Exp Biol Med (Maywood) (2013) 0.76
Changes in autofluorescence based organoid model of muscle invasive urinary bladder cancer. Biomed Opt Express (2016) 0.75
The metabolic interaction of cancer cells and fibroblasts - coupling between NAD(P)H and FAD, intracellular pH and hydrogen peroxide. Cell Cycle (2016) 0.75
Spectrum of spontaneous photon emission as a promising biophysical indicator for breast cancer research. Sci Rep (2017) 0.75
Two-Photon Intravital Fluorescence Lifetime Imaging of the Kidney Reveals Cell-Type Specific Metabolic Signatures. J Am Soc Nephrol (2017) 0.75
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Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature (2006) 8.16
In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia. Proc Natl Acad Sci U S A (2007) 4.53
Molecular and cellular regulation of glucose transporter (GLUT) proteins in cancer. J Cell Physiol (2005) 4.37
Mitochondrial mutations in cancer. Oncogene (2006) 3.86
Oxidation-reduction ratio studies of mitochondria in freeze-trapped samples. NADH and flavoprotein fluorescence signals. J Biol Chem (1979) 3.26
High lactate levels predict likelihood of metastases, tumor recurrence, and restricted patient survival in human cervical cancers. Cancer Res (2000) 3.04
NAD(P)H and collagen as in vivo quantitative fluorescent biomarkers of epithelial precancerous changes. Cancer Res (2002) 1.88
Two-photon autofluorescence dynamics imaging reveals sensitivity of intracellular NADH concentration and conformation to cell physiology at the single-cell level. J Photochem Photobiol B (2008) 1.78
Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. Cancer Treat Rev (2003) 1.76
Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels. Mol Pharmacol (2005) 1.75
MCF7/LCC9: an antiestrogen-resistant MCF-7 variant in which acquired resistance to the steroidal antiestrogen ICI 182,780 confers an early cross-resistance to the nonsteroidal antiestrogen tamoxifen. Cancer Res (1997) 1.74
Estrogen augments glucose transporter and IGF1 expression in primate cerebral cortex. FASEB J (2001) 1.22
Autofluorescence and diffuse reflectance properties of malignant and benign breast tissues. Ann Surg Oncol (2004) 1.19
Regulation of energy metabolism pathways by estrogens and estrogenic chemicals and potential implications in obesity associated with increased exposure to endocrine disruptors. Biochim Biophys Acta (2009) 1.17
Endogenous optical biomarkers of normal and human papillomavirus immortalized epithelial cells. Int J Cancer (2008) 1.16
Estrogen and mitochondria: a new paradigm for vascular protection? Mol Interv (2006) 1.13
Autofluorescence spectroscopy of normal and malignant human breast cell lines. Photochem Photobiol (2003) 1.09
Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring. Photochem Photobiol (2005) 1.05
Proteome analysis for the identification of in vivo estrogen-regulated proteins in bone. Proteomics (2005) 1.04
Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo. J Biomed Opt (2009) 1.03
Measurement of NADH concentration in normal and malignant human tissues from breast and oral cavity. Biotechnol Appl Biochem (2003) 1.00
Rat brain glycolysis regulation by estradiol-17 beta. Biochim Biophys Acta (1992) 0.97
Tamoxifen induced changes in MCF7 human breast cancer: in vitro and in vivo studies using nuclear magnetic resonance spectroscopy and imaging. J Steroid Biochem Mol Biol (1992) 0.96
Regulation of glucose transporters by estradiol in the immature rat uterus. Endocrinology (1999) 0.88
Effect of ovariectomy and estradiol replacement on skeletal muscle enzyme activity in female rats. Metabolism (2002) 0.86
Isocitrate dehydrogenase activity and its regulation by estradiol in tissues of rats of various ages. Cell Biochem Funct (1988) 0.83
14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell (2009) 2.09
Yoga of Awareness program for menopausal symptoms in breast cancer survivors: results from a randomized trial. Support Care Cancer (2009) 1.95
Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins. Opt Express (2010) 1.43
Rapid noninvasive optical imaging of tissue composition in breast tumor margins. Am J Surg (2009) 1.33
A robust Monte Carlo model for the extraction of biological absorption and scattering in vivo. IEEE Trans Biomed Eng (2009) 1.24
Interferon-regulatory factor-1 is critical for tamoxifen-mediated apoptosis in human mammary epithelial cells. Oncogene (2004) 1.13
Uptake of 2-NBDG as a method to monitor therapy response in breast cancer cell lines. Breast Cancer Res Treat (2011) 1.12
Optical assessment of tumor resection margins in the breast. IEEE J Sel Top Quantum Electron (2010) 1.10
Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast. Breast Cancer Res (2010) 1.08
Morphologically normal-appearing mammary epithelial cells obtained from high-risk women exhibit methylation silencing of INK4a/ARF. Clin Cancer Res (2007) 1.05
Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast. PLoS One (2012) 1.04
Optical spectral surveillance of breast tissue landscapes for detection of residual disease in breast tumor margins. PLoS One (2013) 1.03
Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts. J Biomed Opt (2009) 1.03
Optimization of a widefield structured illumination microscope for non-destructive assessment and quantification of nuclear features in tumor margins of a primary mouse model of sarcoma. PLoS One (2013) 1.01
CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis. Cancer Epidemiol Biomarkers Prev (2009) 0.99
Re: Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine. J Natl Cancer Inst (2004) 0.96
Using optical spectroscopy to longitudinally monitor physiological changes within solid tumors. Neoplasia (2009) 0.96
Portable, Fiber-Based, Diffuse Reflection Spectroscopy (DRS) Systems for Estimating Tissue Optical Properties. Appl Spectrosc (2011) 0.95
Hypermethylation of the breast cancer-associated gene 1 promoter does not predict cytologic atypia or correlate with surrogate end points of breast cancer risk. Cancer Epidemiol Biomarkers Prev (2007) 0.95
A low-cost, portable, and quantitative spectral imaging system for application to biological tissues. Opt Express (2010) 0.95
Combined physical and chemical immobilization of glucose oxidase in alginate microspheres improves stability of encapsulation and activity. Bioconjug Chem (2005) 0.95
CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells. Biochem Biophys Res Commun (2003) 0.94
Wavelength optimization for quantitative spectral imaging of breast tumor margins. PLoS One (2013) 0.94
Breast cancer as heterogeneous disease: contributing factors and carcinogenesis mechanisms. Breast Cancer Res Treat (2011) 0.94
Atypia in random periareolar fine-needle aspiration affects the decision of women at high risk to take tamoxifen for breast cancer chemoprevention. Cancer Epidemiol Biomarkers Prev (2007) 0.92
Retinoic acid receptor-beta2 promoter methylation in random periareolar fine needle aspiration. Cancer Epidemiol Biomarkers Prev (2005) 0.92
Stabilization of glucose oxidase in alginate microspheres with photoreactive diazoresin nanofilm coatings. Biotechnol Bioeng (2005) 0.92
Reproducibility of random periareolar fine needle aspiration in a multi-institutional Cancer and Leukemia Group B (CALGB) cross-sectional study. Cancer Epidemiol Biomarkers Prev (2009) 0.90
The antiproliferative effects of PPARgamma ligands in normal human mammary epithelial cells. Breast Cancer Res Treat (2003) 0.89
Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins. PLoS One (2013) 0.86
Pilot and feasibility study: prospective proteomic profiling of mammary epithelial cells from high-risk women provides evidence of activation of pro-survival pathways. Breast Cancer Res Treat (2011) 0.86
Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data. Cancer Epidemiol Biomarkers Prev (2011) 0.86
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system. PLoS One (2012) 0.85
ESR1 promoter hypermethylation does not predict atypia in RPFNA nor persistent atypia after 12 months tamoxifen chemoprevention. Cancer Epidemiol Biomarkers Prev (2008) 0.85
Retinoic acid receptor beta2 inhibition of metastasis in mouse mammary gland xenografts. Breast Cancer Res Treat (2002) 0.85
Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells. Chem Biol (2013) 0.84
CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5. J Cell Sci (2005) 0.83
Preferential accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in breast cancer: a comprehensive study on six breast cell lines with varying phenotypes. J Biomed Opt (2010) 0.82
Polyelectrolyte microshells as carriers for fluorescent sensors: loading and sensing properties of a ruthenium-based oxygen indicator. J Nanosci Nanotechnol (2003) 0.82
Long-term raloxifene in a woman at high risk for breast cancer. N Engl J Med (2006) 0.81
Chromophore based analyses of steady-state diffuse reflectance spectroscopy: current status and perspectives for clinical adoption. J Biophotonics (2014) 0.81
Cancer: Destiny from density. Nature (2012) 0.80
Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300. Microsc Res Tech (2002) 0.80
Tamoxifen and tamoxifen ethyl bromide induce apoptosis in acutely damaged mammary epithelial cells through modulation of AKT activity. Oncogene (2004) 0.80
Metabolic Syndrome and Breast Cancer Risk: Is There a Role for Metformin? Curr Breast Cancer Rep (2011) 0.79
Detection of squamous cell carcinoma and corresponding biomarkers using optical spectroscopy. Otolaryngol Head Neck Surg (2011) 0.78
Delayed-type hypersensitivity reaction with iscador M given in combination with cytotoxic chemotherapy. J Clin Oncol (2004) 0.76
Tumor progression and metastasis from genetic to microenvironmental determinants: a workshop of the tumor progression and metastasis NIH study section in honor of Dr. Martin L. Padarathsingh, May 31, 2006, Georgetown, Washington, DC. Cancer Biol Ther (2006) 0.76
Comments and response on the USPSTF recommendation on screening for breast cancer. Ann Intern Med (2010) 0.75
International Image Concordance Study to Compare a Point-of-Care Tampon Colposcope With a Standard-of-Care Colposcope. J Low Genit Tract Dis (2017) 0.75
Light for Life: International Year of Light 2015. J Biomed Opt (2015) 0.75