Published in Hum Gene Ther on August 01, 2010
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation. Retrovirology (2015) 1.43
Immunization delivered by lentiviral vectors for cancer and infectious diseases. Immunol Rev (2011) 1.18
The inside out of lentiviral vectors. Viruses (2011) 0.85
New approaches to the development of adenoviral dendritic cell vaccines in melanoma. Curr Opin Investig Drugs (2010) 0.83
Development of safer gene delivery systems to minimize the risk of insertional mutagenesis-related malignancies: a critical issue for the field of gene therapy. ISRN Oncol (2012) 0.82
Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines. Retrovirology (2012) 0.81
Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques. Mol Ther (2016) 0.81
Retroviral and lentiviral vectors for the induction of immunological tolerance. Scientifica (Cairo) (2012) 0.80
Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response. EMBO Mol Med (2015) 0.80
Mucosal immunization with integrase-defective lentiviral vectors protects against influenza virus challenge in mice. PLoS One (2014) 0.79
Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors. Mol Ther Methods Clin Dev (2015) 0.79
Optimization of mucosal responses after intramuscular immunization with integrase defective lentiviral vector. PLoS One (2014) 0.79
Recent Advances in Lentiviral Vaccines for HIV-1 Infection. Front Immunol (2016) 0.75
Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2. Nature (1987) 4.66
Engineered lentivector targeting of dendritic cells for in vivo immunization. Nat Biotechnol (2008) 2.05
Targeting dendritic cell signaling to regulate the response to immunization. Blood (2008) 1.50
Integration-deficient lentiviral vectors: a slow coming of age. Mol Ther (2009) 1.47
Human macrophages support persistent transcription from unintegrated HIV-1 DNA. Virology (2007) 1.46
Both dendritic cells and macrophages can stimulate naive CD8 T cells in vivo to proliferate, develop effector function, and differentiate into memory cells. J Immunol (2005) 1.43
Integrase-defective lentiviral vectors: progress and applications. Gene Ther (2009) 1.41
Successful immunization with a single injection of non-integrating lentiviral vector. Mol Ther (2007) 1.31
Self-limiting, cell type-dependent replication of an integrase-defective human immunodeficiency virus type 1 in human primary macrophages but not T lymphocytes. Virology (1995) 1.25
Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy. J Virol (2009) 1.24
Protective antiviral immunity conferred by a nonintegrative lentiviral vector-based vaccine. PLoS One (2008) 1.16
HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages. Viral Immunol (2005) 1.15
Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system. Mol Ther (2000) 1.11
SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors. Gene Ther (2008) 1.03
Lentiviral vector-based prime/boost vaccination against AIDS: pilot study shows protection against Simian immunodeficiency virus SIVmac251 challenge in macaques. J Virol (2009) 1.02
Lentivirus as a potent and mechanistically distinct vector for genetic immunization. Curr Opin Mol Ther (2007) 0.97
Retroviral E-DNA: persistence and gene expression in nondividing immune cells. J Leukoc Biol (2006) 0.95
Development of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compounds. Antimicrob Agents Chemother (2006) 0.94
Persistent transcription of a nonintegrating mutant of simian immunodeficiency virus in rhesus macrophages. Virology (2007) 0.93
Development and use of SIV-based Integrase defective lentiviral vector for immunization. Vaccine (2009) 0.92
Nonintegrating lentiviral vectors can effectively deliver ovalbumin antigen for induction of antitumor immunity. Hum Gene Ther (2009) 0.90
Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc Natl Acad Sci U S A (2002) 4.26
Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease. Nat Genet (2003) 2.88
Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality. AIDS (2006) 2.28
Slower fibrosis progression in HIV/HCV-coinfected patients with successful HIV suppression using antiretroviral therapy. J Hepatol (2005) 2.27
Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat Med (2002) 2.10
Chronic kidney disease in HIV infection: an urban epidemic. AIDS (2007) 1.97
Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease. J Am Soc Nephrol (2005) 1.94
HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. J Am Soc Nephrol (2002) 1.79
Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. J Clin Invest (2004) 1.71
Candidate topical microbicides bind herpes simplex virus glycoprotein B and prevent viral entry and cell-to-cell spread. Antimicrob Agents Chemother (2004) 1.69
APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. J Am Soc Nephrol (2011) 1.67
Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. J Am Soc Nephrol (2011) 1.66
Human immunodeficiency virus (HIV) infects human arterial smooth muscle cells in vivo and in vitro: implications for the pathogenesis of HIV-mediated vascular disease. Am J Pathol (2008) 1.60
PRO 2000 gel inhibits HIV and herpes simplex virus infection following vaginal application: a double-blind placebo-controlled trial. J Infect Dis (2005) 1.54
Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. J Clin Invest (2005) 1.47
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation. Retrovirology (2015) 1.43
HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells. J Acquir Immune Defic Syndr (2006) 1.37
HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. AIDS (2005) 1.36
The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy. Kidney Int (2008) 1.33
Candidate sulfonated and sulfated topical microbicides: comparison of anti-human immunodeficiency virus activities and mechanisms of action. Antimicrob Agents Chemother (2005) 1.31
Successful immunization with a single injection of non-integrating lentiviral vector. Mol Ther (2007) 1.31
Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infection. J Infect Dis (2005) 1.29
Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages. J Virol (2003) 1.26
Career outcomes of the graduates of the American Board of Internal Medicine Research Pathway, 1995-2007. Acad Med (2013) 1.24
CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition. J Virol (2003) 1.17
Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. J Am Soc Nephrol (2006) 1.17
HIV-1 extrachromosomal 2-LTR circular DNA is long-lived in human macrophages. Viral Immunol (2005) 1.15
alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s). J Infect Dis (2007) 1.14
Unraveling cancer chemoimmunotherapy mechanisms by gene and protein expression profiling of responses to cyclophosphamide. Cancer Res (2011) 1.13
Persulfated molecular umbrellas as anti-HIV and anti-HSV agents. J Am Chem Soc (2004) 1.07
Virological consequences of early events following cell-cell contact between human immunodeficiency virus type 1-infected and uninfected CD4+ cells. J Virol (2008) 1.06
HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. Kidney Int (2008) 1.05
The Contribution of Agriculture, Forestry and other Land Use activities to Global Warming, 1990-2012. Glob Chang Biol (2015) 1.03
A soluble factor(s) secreted from CD8(+) T lymphocytes inhibits human immunodeficiency virus type 1 replication through STAT1 activation. J Virol (2002) 1.03
ACIDFORM inactivates herpes simplex virus and prevents genital herpes in a mouse model: optimal candidate for microbicide combinations. J Infect Dis (2006) 1.02
The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome. Mech Ageing Dev (2005) 1.01
Long-term protection against SHIV89.6P replication in HIV-1 Tat vaccinated cynomolgus monkeys. Vaccine (2004) 1.01
Neisseria gonorrhoeae enhances HIV-1 infection of primary resting CD4+ T cells through TLR2 activation. J Immunol (2010) 1.01
Acetylcholinesterase inhibitors effects on oncostatin-M, interleukin-1 beta and interleukin-6 release from lymphocytes of Alzheimer's disease patients. Exp Gerontol (2005) 1.00
HIV-1 Tat addresses dendritic cells to induce a predominant Th1-type adaptive immune response that appears prevalent in the asymptomatic stage of infection. J Immunol (2009) 1.00
FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy. J Virol (2009) 1.00
Macaca mulatta, fascicularis and nemestrina in AIDS vaccine development. Expert Rev Vaccines (2008) 1.00
Defensins: natural anti-HIV peptides. AIDS Rev (2004) 0.99
Nef expressed from human immunodeficiency virus type 1 extrachromosomal DNA downregulates CD4 on primary CD4+ T lymphocytes: implications for integrase inhibitors. J Gen Virol (2005) 0.97
HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein. Retrovirology (2007) 0.96
Protective efficacy of a multicomponent vector vaccine in cynomolgus monkeys after intrarectal simian immunodeficiency virus challenge. J Gen Virol (2004) 0.96
Treatment with an acetylcholinesterase inhibitor in Alzheimer patients modulates the expression and production of the pro-inflammatory and anti-inflammatory cytokines. J Neuroimmunol (2004) 0.96
Retroviral E-DNA: persistence and gene expression in nondividing immune cells. J Leukoc Biol (2006) 0.95
Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction. Proc Natl Acad Sci U S A (2010) 0.95
Development of a human immunodeficiency virus vector-based, single-cycle assay for evaluation of anti-integrase compounds. Antimicrob Agents Chemother (2006) 0.94
Evaluation of a self-inactivating lentiviral vector expressing simian immunodeficiency virus gag for induction of specific immune responses in vitro and in vivo. Viral Immunol (2006) 0.92
Lentiviral gene transduction of kidney. Hum Gene Ther (2002) 0.92
Development and use of SIV-based Integrase defective lentiviral vector for immunization. Vaccine (2009) 0.92
HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. AIDS (2010) 0.92
Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. J Biol Chem (2003) 0.92
A single administration of lentiviral vectors expressing either full-length human immunodeficiency virus 1 (HIV-1)(HXB2) Rev/Env or codon-optimized HIV-1(JR-FL) gp120 generates durable immune responses in mice. J Gen Virol (2006) 0.91
HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies. PLoS One (2012) 0.91
HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells. AIDS (2009) 0.90
Successful therapeutic vaccination with integrase defective lentiviral vector expressing nononcogenic human papillomavirus E7 protein. Int J Cancer (2012) 0.90
Kidney and central nervous system as reservoirs of HIV infection. Curr Opin HIV AIDS (2006) 0.89
Gonococcal lipooligosaccharide suppresses HIV infection in human primary macrophages through induction of innate immunity. J Infect Dis (2006) 0.89
Multicolor bioluminescence boosts malaria research: quantitative dual-color assay and single-cell imaging in Plasmodium falciparum parasites. Anal Chem (2014) 0.88
Nonintegrating Lentiviral Vector-Based Vaccine Efficiently Induces Functional and Persistent CD8+ T Cell Responses in Mice. J Biomed Biotechnol (2010) 0.87
Topical microbicides: the time has come. AIDS Read (2006) 0.86
The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy. FASEB J (2007) 0.86
Identification of a cytotoxic T-lymphocyte (CTL) epitope recognized by Gag-specific CTLs in cynomolgus monkeys infected with simian/human immunodeficiency virus. J Gen Virol (2006) 0.86