Published in Apoptosis on July 01, 2010
Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II. J Biol Chem (2010) 1.16
Mitochondrial permeability transition pore as a selective target for anti-cancer therapy. Front Oncol (2013) 0.89
Mitochondrially targeted α-tocopheryl succinate is antiangiogenic: potential benefit against tumor angiogenesis but caution against wound healing. Antioxid Redox Signal (2011) 0.82
Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death. PLoS One (2012) 0.81
Use of anti-cancer drugs, mitocans, to enhance the immune responses against tumors. Curr Pharm Biotechnol (2013) 0.78
Mitochondrial Pathway of α-Tocopheryl Succinate-Induced Apoptosis in Human Epidermoid Carcinoma A431 Cells. Acta Naturae (2012) 0.75
Conjugated equine estrogens and global cognitive function in postmenopausal women: Women's Health Initiative Memory Study. JAMA (2004) 3.85
HIV infection and bone mineral density in middle-aged women. Clin Infect Dis (2006) 2.67
Decreased bone mineral density and increased fracture risk in aging men with or at risk for HIV infection. AIDS (2007) 1.95
HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms. Mini Rev Med Chem (2009) 1.85
The causes of cancer revisited: "mitochondrial malignancy" and ROS-induced oncogenic transformation - why mitochondria are targets for cancer therapy. Mol Aspects Med (2010) 1.84
Familial and cultural perceptions and beliefs of oral hygiene and dietary practices among ethnically and socio-economicall diverse groups. Community Dent Health (2004) 1.78
Obesity and dental caries in children: a systematic review and meta-analysis. Community Dent Oral Epidemiol (2012) 1.71
Oral health-related quality of life for 8-10-year-old children: an assessment of a new measure. Community Dent Oral Epidemiol (2005) 1.60
Tumour-initiating cells vs. cancer 'stem' cells and CD133: what's in the name? Biochem Biophys Res Commun (2007) 1.57
The European perspective on vitamin E: current knowledge and future research. Am J Clin Nutr (2002) 1.57
Empirical evidence of the relationship between parental and child dental fear: a structured review and meta-analysis. Int J Paediatr Dent (2010) 1.49
Association of pelvic organ prolapse and fractures in postmenopausal women: analysis of baseline data from the Women's Health Initiative Estrogen Plus Progestin trial. Menopause (2008) 1.47
Reliability and validity of a faces version of the Modified Child Dental Anxiety Scale. Int J Paediatr Dent (2007) 1.37
Reforming NHS dentistry. BMJ (2008) 1.35
International comparisons of health inequalities in childhood dental caries. Community Dent Health (2004) 1.34
Psychological stress in undergraduate dental students: baseline results from seven European dental schools. Eur J Dent Educ (2002) 1.34
Recognizing and reporting child physical abuse: a survey of primary healthcare professionals. J Adv Nurs (2006) 1.33
Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1. J Biol Chem (2002) 1.26
MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells. Cancer Res (2012) 1.21
Fat distribution in HIV-infected women in the United States: DEXA substudy in the Women's Interagency HIV Study. J Acquir Immune Defic Syndr (2005) 1.20
HIF expression and the role of hypoxic microenvironments within primary tumours as protective sites driving cancer stem cell renewal and metastatic progression. Carcinogenesis (2013) 1.19
Aging of cardiac myocytes in culture: oxidative stress, lipofuscin accumulation, and mitochondrial turnover. Ann N Y Acad Sci (2004) 1.17
Molecular mechanism of 'mitocan'-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins. FEBS Lett (2006) 1.16
Mitochondrial targeting of vitamin E succinate enhances its pro-apoptotic and anti-cancer activity via mitochondrial complex II. J Biol Chem (2010) 1.16
The association of bone mineral density with HIV infection and antiretroviral treatment in women. Antivir Ther (2007) 1.13
Sleep Complaints of Postmenopausal Women. Clin J Womens Health (2001) 1.13
Mitochondrial recycling and aging of cardiac myocytes: the role of autophagocytosis. Exp Gerontol (2003) 1.13
Bioenergetic pathways in tumor mitochondria as targets for cancer therapy and the importance of the ROS-induced apoptotic trigger. Mol Aspects Med (2009) 1.12
Vitamin E analogs, a novel group of "mitocans," as anticancer agents: the importance of being redox-silent. Mol Pharmacol (2007) 1.11
Galectin-1 as a potent target for cancer therapy: role in the tumor microenvironment. Cancer Metastasis Rev (2012) 1.10
Classification of mitocans, anti-cancer drugs acting on mitochondria. Mitochondrion (2012) 1.10
Developing explanatory models of health inequalities in childhood dental caries. Community Dent Health (2004) 1.10
Suppression of tumor growth in vivo by the mitocan alpha-tocopheryl succinate requires respiratory complex II. Clin Cancer Res (2009) 1.09
Variations in hip fracture hospitalization rates among different race/ethnicity groups in New York City. Ethn Dis (2004) 1.08
Mitocans as anti-cancer agents targeting mitochondria: lessons from studies with vitamin E analogues, inhibitors of complex II. J Bioenerg Biomembr (2007) 1.08
Mitochondria as targets for cancer therapy. Mol Nutr Food Res (2009) 1.08
Mitochondrially targeted anti-cancer agents. Mitochondrion (2010) 1.08
Vitamin E analogues as a novel group of mitocans: anti-cancer agents that act by targeting mitochondria. Mol Aspects Med (2007) 1.07
Vitamin E succinate is a potent novel antineoplastic agent with high selectivity and cooperativity with tumor necrosis factor-related apoptosis-inducing ligand (Apo2 ligand) in vivo. Clin Cancer Res (2002) 1.07
Clinical significance of circulating miR-126 quantification in malignant mesothelioma patients. Clin Biochem (2012) 1.06
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model. Cancer Lett (2010) 1.04
Anticancer drugs targeting the mitochondrial electron transport chain. Antioxid Redox Signal (2011) 1.04
Vitamin E analogues inhibit angiogenesis by selective induction of apoptosis in proliferating endothelial cells: the role of oxidative stress. Cancer Res (2007) 1.04
Mitochondrial complex II, a novel target for anti-cancer agents. Biochim Biophys Acta (2012) 1.03
Mitochondria play a central role in apoptosis induced by alpha-tocopheryl succinate, an agent with antineoplastic activity: comparison with receptor-mediated pro-apoptotic signaling. Biochemistry (2003) 1.02
Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma. PLoS One (2011) 1.01
UK population norms for the modified dental anxiety scale with percentile calculator: adult dental health survey 2009 results. BMC Oral Health (2013) 1.00
A systematic review and meta-analysis of face-to-face communication of tailored health messages: implications for practice. Patient Educ Couns (2011) 0.99
Remembering and repeating childhood dental treatment experiences: parents, their children, and barriers to dental care. Int J Paediatr Dent (2009) 0.99
alpha-Lipoic acid supplementation inhibits oxidative damage, accelerating chronic wound healing in patients undergoing hyperbaric oxygen therapy. Biochem Biophys Res Commun (2005) 0.99
Low-fat, increased fruit, vegetable, and grain dietary pattern, fractures, and bone mineral density: the Women's Health Initiative Dietary Modification Trial. Am J Clin Nutr (2009) 0.98
Vitamin E analogues as anticancer agents: lessons from studies with alpha-tocopheryl succinate. Mol Nutr Food Res (2006) 0.98
Some psychometric properties of the Chinese version of the Modified Dental Anxiety Scale with cross validation. Health Qual Life Outcomes (2008) 0.96
CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP. Biochem Biophys Res Commun (2008) 0.95
Alpha-tocopheryl succinate inhibits malignant mesothelioma by disrupting the fibroblast growth factor autocrine loop: mechanism and the role of oxidative stress. J Biol Chem (2005) 0.93
A peptide conjugate of vitamin E succinate targets breast cancer cells with high ErbB2 expression. Cancer Res (2007) 0.92
Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner. Cancer Res (2011) 0.92
Elevated levels of Factor XI are associated with cardiovascular disease in women. Thromb Res (2002) 0.92
Inhibiting galectin-1 reduces murine lung metastasis with increased CD4(+) and CD8 (+) T cells and reduced cancer cell adherence. Clin Exp Metastasis (2012) 0.91
Thiodigalactoside inhibits murine cancers by concurrently blocking effects of galectin-1 on immune dysregulation, angiogenesis and protection against oxidative stress. Angiogenesis (2011) 0.91
Reactive oxygen species are generated by the respiratory complex II--evidence for lack of contribution of the reverse electron flow in complex I. FEBS J (2013) 0.91
Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties. Biochem Pharmacol (2003) 0.91
Mitochondria transmit apoptosis signalling in cardiomyocyte-like cells and isolated hearts exposed to experimental ischemia-reperfusion injury. Redox Rep (2007) 0.90
Alpha-tocopheryl succinate induces DR4 and DR5 expression by a p53-dependent route: implication for sensitisation of resistant cancer cells to TRAIL apoptosis. FEBS Lett (2006) 0.90
Mitocans: mitochondrial targeted anti-cancer drugs as improved therapies and related patent documents. Recent Pat Anticancer Drug Discov (2006) 0.89
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: a new paradigm for effective cancer therapy. Free Radic Biol Med (2011) 0.88
Vulnerability and presenting symptoms in burning mouth syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2005) 0.88
Targeting the mitochondrial electron transport chain complexes for the induction of apoptosis and cancer treatment. Curr Pharm Biotechnol (2013) 0.87
Profiling tumor-associated markers for early detection of malignant mesothelioma: an epidemiologic study. Cancer Epidemiol Biomarkers Prev (2008) 0.87
Evaluating a single dental anxiety question in Finnish adults. Acta Odontol Scand (2007) 0.87