Published in FASEB J on March 10, 2010
Dietary and genetic evidence for enhancing glucose metabolism and reducing obesity by inhibiting klotho functions. FASEB J (2011) 0.95
Metallothionein and the biology of aging. Ageing Res Rev (2010) 0.91
Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome. PLoS One (2013) 0.91
Characterization of MtnE, the fifth metallothionein member in Drosophila. J Biol Inorg Chem (2011) 0.90
Zinc transporter Slc39a14 regulates inflammatory signaling associated with hypertrophic adiposity. Am J Physiol Endocrinol Metab (2015) 0.87
The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective. Int J Mol Sci (2016) 0.81
Modeling partial monosomy for human chromosome 21q11.2-q21.1 reveals haploinsufficient genes influencing behavior and fat deposition. PLoS One (2012) 0.80
Social overcrowding as a chronic stress model that increases adiposity in mice. Psychoneuroendocrinology (2014) 0.76
Metallothioneins 1 and 2, but not 3, are regulated by nutritional status in rat white adipose tissue. Genes Nutr (2016) 0.76
Metallothioneins regulate the adipogenic differentiation of 3T3-L1 cells via the insulin signaling pathway. PLoS One (2017) 0.75
WTC rat has unique characteristics such as resistant to streptozotocin. Biochem Biophys Rep (2016) 0.75
Obesity paradox in Japanese patients after percutaneous coronary intervention: an observation cohort study. J Cardiol (2013) 3.36
Requirement of arsenic biomethylation for oxidative DNA damage. J Natl Cancer Inst (2009) 1.96
The anticancer natural product pironetin selectively targets Lys352 of alpha-tubulin. Chem Biol (2004) 1.59
Progression to the persistent form in asymptomatic paroxysmal atrial fibrillation. Circ J (2014) 1.44
An expiratory assist during spontaneous breathing can compensate for endotracheal tube resistance. Anesth Analg (2009) 1.41
Impact of early statin initiation on secondary prevention in Japanese patients with coronary artery disease. J Cardiol (2010) 1.41
Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals. Tohoku J Exp Med (2002) 1.24
Characteristics of congestive heart failure accompanied by atrial fibrillation with special reference to tachycardia-induced cardiomyopathy. Circ J (2007) 1.22
Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2. J Cell Physiol (2005) 1.21
Silica nanoparticles as hepatotoxicants. Eur J Pharm Biopharm (2009) 1.20
miR-122a-regulated expression of a suicide gene prevents hepatotoxicity without altering antitumor effects in suicide gene therapy. Mol Ther (2008) 1.13
Cadmium induces apoptosis partly via caspase-9 activation in HL-60 cells. Toxicology (2002) 1.12
Enzymatic activity of lysosomal carboxypeptidase (cathepsin) A is required for proper elastic fiber formation and inactivation of endothelin-1. Circulation (2008) 1.10
Histological analysis of 70-nm silica particles-induced chronic toxicity in mice. Eur J Pharm Biopharm (2009) 1.07
Domain mapping of a claudin-4 modulator, the C-terminal region of C-terminal fragment of Clostridium perfringens enterotoxin, by site-directed mutagenesis. Biochem Pharmacol (2008) 1.05
Hepatoprotective effect of syringic acid and vanillic acid on concanavalin a-induced liver injury. Biol Pharm Bull (2009) 1.05
Medium (DMEM/F12)-containing chitosan hydrogel as adhesive and dressing in autologous skin grafts and accelerator in the healing process. J Biomed Mater Res B Appl Biomater (2006) 1.03
Androgen-dependent gene expression of prostate-specific antigen is enhanced synergistically by hypoxia in human prostate cancer cells. Mol Cancer Res (2007) 1.02
Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure. Nanotechnology (2012) 1.02
Role of tyrosine residues in modulation of claudin-4 by the C-terminal fragment of Clostridium perfringens enterotoxin. Biochem Pharmacol (2006) 1.02
An integrative study of the genetic, social and environmental determinants of chronic kidney disease characterized by tubulointerstitial damages in the North Central Region of Sri Lanka. J Occup Health (2013) 1.01
Hepatoprotective effect of syringic acid and vanillic acid on CCl4-induced liver injury. Biol Pharm Bull (2010) 1.00
Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh. Environ Health (2011) 1.00
A novel method for predicting disintegration time in the mouth of rapidly disintegrating tablet by compaction analysis using TabAll. Chem Pharm Bull (Tokyo) (2004) 0.99
Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells. Eur J Biochem (2002) 0.99
Non-contact respiratory monitoring system using a ceiling-attached microwave antenna. Med Biol Eng Comput (2006) 0.99
Multipotent cells from the human third molar: feasibility of cell-based therapy for liver disease. Differentiation (2007) 0.98
A novel tumor-targeted therapy using a claudin-4-targeting molecule. Mol Pharmacol (2009) 0.98
Effects of statin treatment in patients with coronary artery disease and chronic kidney disease. Heart Vessels (2013) 0.97
Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells. Metallomics (2012) 0.97
Role of C-terminal regions of the C-terminal fragment of Clostridium perfringens enterotoxin in its interaction with claudin-4. J Control Release (2005) 0.97
Long-term incidence and prognostic factors of the progression of new coronary lesions in Japanese coronary artery disease patients after percutaneous coronary intervention. Heart Vessels (2013) 0.95
Metallothionein is a crucial protective factor against Helicobacter pylori-induced gastric erosive lesions in a mouse model. Am J Physiol Gastrointest Liver Physiol (2008) 0.94
Preparation of a claudin-targeting molecule using a C-terminal fragment of Clostridium perfringens enterotoxin. J Pharmacol Exp Ther (2005) 0.93
Use of human hepatocyte-like cells derived from induced pluripotent stem cells as a model for hepatocytes in hepatitis C virus infection. Biochem Biophys Res Commun (2011) 0.93
Overexpression of thioredoxin reductase 1 regulates NF-kappa B activation. J Cell Physiol (2004) 0.93
Impact of aging on the clinical outcomes of Japanese patients with coronary artery disease after percutaneous coronary intervention. Heart Vessels (2013) 0.93
Preparation, characterization, and tableting of a solid dispersion of indomethacin with crospovidone. Int J Pharm (2005) 0.92
The effect of chitosan hydrogel containing DMEM/F12 medium on full-thickness skin defects after deep dermal burn. Burns (2007) 0.92
Increases in oxidized low-density lipoprotein and other inflammatory and adhesion molecules with a concomitant decrease in high-density lipoprotein in the individuals exposed to arsenic in Bangladesh. Toxicol Sci (2013) 0.90
Effect of powder characteristics on oral tablet disintegration. Int J Pharm (2008) 0.90
A claudin-targeting molecule as an inhibitor of tumor metastasis. J Pharmacol Exp Ther (2010) 0.89
Reduction of drug leakage by negative-balance isolated pelvic perfusion: correlation between leakage and in-out flow rate in a pig model. J Cancer Res Clin Oncol (2005) 0.88
Effect of N-methyl-2-pyrrolidone on skin permeation of estradiol. Eur J Pharm Biopharm (2004) 0.88
In vivo estrogenic potential of 4-methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene, an active metabolite of bisphenol A, in uterus of ovariectomized rat. Toxicol Lett (2010) 0.88
Chronic exposure to methylated arsenicals stimulates arsenic excretion pathways and induces arsenic tolerance in rat liver cells. Toxicol Sci (2006) 0.88
A claudin-4 modulator enhances the mucosal absorption of a biologically active peptide. Biochem Pharmacol (2010) 0.88
Altered protein profile and possible hypoxia in the placenta of 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed rats. Toxicol Appl Pharmacol (2002) 0.88
Novel chronotherapeutic rectal aminophylline delivery system for therapy of asthma. Int J Pharm (2009) 0.88
Association between arsenic exposure and plasma cholinesterase activity: a population based study in Bangladesh. Environ Health (2010) 0.87
Suppressive effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on vascular remodeling that takes place in the normal labyrinth zone of rat placenta during late gestation. Toxicol Sci (2006) 0.87
Role of Tyr306 in the C-terminal fragment of Clostridium perfringens enterotoxin for modulation of tight junction. Biochem Pharmacol (2006) 0.87
Proof of concept for claudin-targeted drug development. Ann N Y Acad Sci (2012) 0.86
Effects of vinclozolin administration on sperm production and testosterone biosynthetic pathway in adult male rat. J Reprod Dev (2003) 0.86
Role of N-terminal amino acids in the absorption-enhancing effects of the c-terminal fragment of Clostridium perfringens enterotoxin. J Pharmacol Exp Ther (2005) 0.86
Dioxin-induced toxicity on vascular remodeling of the placenta. Biochem Pharmacol (2008) 0.86
Mercuric chloride induces apoptosis via a mitochondrial-dependent pathway in human leukemia cells. Toxicology (2003) 0.86
Increased expression of matrix metalloproteinase-2 in nasal polyps. Acta Otolaryngol (2004) 0.86
Prevalence and the long-term prognosis of functional mitral regurgitation in Japanese patients with symptomatic heart failure. Heart Vessels (2013) 0.85
Effect of thrombin on permeability of human epithelial cell monolayers. Pharmacology (2005) 0.85
Tissue-dependent preventive effect of metallothionein against DNA damage in dyslipidemic mice under repeated stresses of fasting or restraint. Life Sci (2009) 0.85
Selected ventriculoplasty for idiopathic dilated cardiomyopathy with advanced congestive heart failure: midterm results and risk analysis. Eur J Cardiothorac Surg (2007) 0.85
Acute and chronic nephrotoxicity of platinum nanoparticles in mice. Nanoscale Res Lett (2013) 0.85
Cytolethality of glutathione conjugates with monomethylarsenic or dimethylarsenic compounds. Biol Pharm Bull (2005) 0.84
Fucoidan partly prevents CCl4-induced liver fibrosis. Eur J Pharmacol (2007) 0.84
Prevalence and prognosis of patients with heart failure in Tokyo: a prospective cohort of Shinken Database 2004-5. Int Heart J (2009) 0.84
Prevention of hepatic ischemia-reperfusion injury by pre-administration of catalase-expressing adenovirus vectors. J Control Release (2009) 0.83
Effect of pH on 1H-NMR spectroscopy of mouse urine. Biol Pharm Bull (2007) 0.83
Involvement of DNA hypermethylation in down-regulation of the zinc transporter ZIP8 in cadmium-resistant metallothionein-null cells. Toxicol Appl Pharmacol (2009) 0.83
Proteomic alteration in gastic adenocarcinomas from Japanese patients. Mol Cancer (2006) 0.83
Protective effects of the dietary supplementation of turmeric (Curcuma longa L.) on sodium arsenite-induced biochemical perturbation in mice. Bangladesh Med Res Counc Bull (2010) 0.83
Effects of nicorandil on cardiovascular events in patients with coronary artery disease in the Japanese Coronary Artery Disease (JCAD) study. Circ J (2010) 0.83
Induction of metallothionein by manganese is completely dependent on interleukin-6 production. J Pharmacol Exp Ther (2006) 0.82
Gene expression of mesoderm-specific transcript is upregulated as preadipocytes differentiate to adipocytes in vitro. J Physiol Sci (2012) 0.82
Clinical outcome after acute coronary syndrome in Japanese patients: an observational cohort study. J Cardiol (2009) 0.82
Protection against D-galactosamine-induced acute liver injury by oral administration of extracts from Lentinus edodes mycelia. Biol Pharm Bull (2006) 0.82
Nonviral retrograde gene transfer of human hepatocyte growth factor improves neuropathic pain-related phenomena in rats. Mol Ther (2008) 0.82
Elevated levels of plasma Big endothelin-1 and its relation to hypertension and skin lesions in individuals exposed to arsenic. Toxicol Appl Pharmacol (2012) 0.82
Preventive mechanism of cellular glutathione in monomethylarsonic acid-induced cytolethality. Toxicol Appl Pharmacol (2004) 0.82
A comparison of apoptosis and necrosis induced by ent-kaurene-type diterpenoids in HL-60 cells. Planta Med (2004) 0.82
Activation of caspase-3 in HL-60 cells treated with pyrithione and zinc. Biol Pharm Bull (2005) 0.82
Rat H9c2 cardiac myocytes are sensitive to arsenite due to a modest activation of transcription factor Nrf2. Arch Toxicol (2011) 0.82
Visualization of conformational distribution of short to medium size segments in globular proteins and identification of local structural motifs. Protein Sci (2005) 0.82
[Application of mesenchymal stem cells to liver regenerative medicine]. Yakugaku Zasshi (2008) 0.82
[Apoptosis-inducing properties of ent-kaurene-type diterpenoids from the liverwort Jungermannia truncata]. Planta Med (2003) 0.82
Interaction between chronic arsenic exposure via drinking water and plasma lactate dehydrogenase activity. Sci Total Environ (2010) 0.81
High sensitivity of RBL-2H3 cells to cadmium and manganese: an implication of the role of ZIP8. Metallomics (2011) 0.81
Role of arsenic (+3 oxidation state) methyltransferase in arsenic metabolism and toxicity. Biol Pharm Bull (2012) 0.81
Novel pathway of metabolic activation of bisphenol A-related compounds for estrogenic activity. Drug Metab Dispos (2011) 0.81
Comparative contribution of the aryl hydrocarbon receptor gene to perinatal stage development and dioxin-induced toxicity between the urogenital complex and testis in the mouse. Biol Reprod (2009) 0.81
Claudin-4-targeting of diphtheria toxin fragment A using a C-terminal fragment of Clostridium perfringens enterotoxin. Eur J Pharm Biopharm (2010) 0.81
Effect of characteristics of compounds on maintenance of an amorphous state in solid dispersion with crospovidone. J Pharm Sci (2007) 0.81
Whole-cell arsenite biosensor using photosynthetic bacterium Rhodovulum sulfidophilum. Rhodovulum sulfidophilum as an arsenite biosensor. Appl Microbiol Biotechnol (2006) 0.81
Mutated C-terminal fragments of Clostridium perfringens enterotoxin have increased affinity to claudin-4 and reversibly modulate tight junctions in vitro. Biochem Biophys Res Commun (2011) 0.80
Interleukin-6 enhances manganese accumulation in SH-SY5Y cells: implications of the up-regulation of ZIP14 and the down-regulation of ZnT10. Metallomics (2014) 0.80
Development of vizantin, a safe immunostimulant, based on the structure-activity relationship of trehalose-6,6'-dicorynomycolate. J Med Chem (2012) 0.80
Cross-resistance of cadmium-resistant cells to manganese is associated with reduced accumulation of both cadmium and manganese. Toxicology (2010) 0.80