1
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Triple-negative breast cancer: clinical features and patterns of recurrence.
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Clin Cancer Res
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2007
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16.79
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2
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Twenty five year follow-up for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial.
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BMJ
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2014
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8.49
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3
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Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations.
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N Engl J Med
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2002
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8.09
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4
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Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada.
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J Natl Cancer Inst
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2006
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6.73
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5
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Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy.
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J Urol
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6.01
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6
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Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography, and clinical breast examination.
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JAMA
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2004
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5.85
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7
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Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.
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J Clin Oncol
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2004
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5.38
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8
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Common variants at 19p13 are associated with susceptibility to ovarian cancer.
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Nat Genet
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2010
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4.51
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9
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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
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Nat Genet
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2013
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4.35
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10
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Clinical outcomes of breast cancer in carriers of BRCA1 and BRCA2 mutations.
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N Engl J Med
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2007
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4.25
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11
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Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation.
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JAMA
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2006
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4.09
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12
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Improved survival in women with BRCA-associated ovarian carcinoma.
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2003
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3.96
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13
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A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.
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Nat Genet
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2010
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3.86
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14
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Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers.
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3.86
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15
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RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies.
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Am J Hum Genet
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2007
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3.63
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16
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Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.
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J Clin Oncol
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2005
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3.44
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17
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GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.
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Nat Genet
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3.42
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18
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Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers.
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Gynecol Oncol
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2005
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3.26
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19
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PPM1D mutations in circulating white blood cells and the risk for ovarian cancer.
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J Natl Cancer Inst
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2013
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3.15
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20
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Expression of TMPRSS2:ERG gene fusion in prostate cancer cells is an important prognostic factor for cancer progression.
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Cancer Biol Ther
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2007
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2.97
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21
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Satisfaction with breast reconstruction in women with bilateral prophylactic mastectomy: a descriptive study.
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2.88
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22
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Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers.
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J Natl Cancer Inst
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2008
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2.78
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23
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Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.
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J Clin Oncol
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2005
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2.70
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24
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Pattern of metastatic spread in triple-negative breast cancer.
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Breast Cancer Res Treat
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2008
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2.65
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25
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Contralateral mastectomy and survival after breast cancer in carriers of BRCA1 and BRCA2 mutations: retrospective analysis.
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BMJ
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2014
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2.60
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26
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Increasing hospital admission rates for urological complications after transrectal ultrasound guided prostate biopsy.
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J Urol
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2013
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2.53
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27
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Estrogen receptor status in BRCA1- and BRCA2-related breast cancer: the influence of age, grade, and histological type.
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Clin Cancer Res
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2004
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2.51
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28
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Ten-year multi-institutional results of breast-conserving surgery and radiotherapy in BRCA1/2-associated stage I/II breast cancer.
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J Clin Oncol
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2006
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2.49
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29
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A range of cancers is associated with the rs6983267 marker on chromosome 8.
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Cancer Res
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2008
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2.43
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30
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Tamoxifen and contralateral breast cancer in BRCA1 and BRCA2 carriers: an update.
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Int J Cancer
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2006
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2.41
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31
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Analysis of PALB2/FANCN-associated breast cancer families.
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Proc Natl Acad Sci U S A
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2007
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2.41
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32
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Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
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PLoS Genet
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2013
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2.39
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33
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Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature.
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J Clin Oncol
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2004
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2.25
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34
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Prospective multi-institutional study evaluating the performance of prostate cancer risk calculators.
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J Clin Oncol
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2011
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2.21
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35
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Screening for founder mutations in BRCA1 and BRCA2 in unselected Jewish women.
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J Clin Oncol
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2009
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2.20
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36
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Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer.
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Gynecol Oncol
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2011
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2.19
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37
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Prospective study of breast cancer incidence in women with a BRCA1 or BRCA2 mutation under surveillance with and without magnetic resonance imaging.
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J Clin Oncol
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2011
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2.17
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38
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Assessing individual risk for prostate cancer.
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J Clin Oncol
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2.13
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39
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International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers.
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Int J Cancer
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2008
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2.13
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40
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The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.
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Clin Cancer Res
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2011
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2.09
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41
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Association between germline HOXB13 G84E mutation and risk of prostate cancer.
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J Natl Cancer Inst
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2.06
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42
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The prevalence of BRCA1 mutations among young women with triple-negative breast cancer.
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BMC Cancer
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2.01
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43
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Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women.
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Breast Cancer Res
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2007
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2.00
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44
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Risk of breast cancer in women with a CHEK2 mutation with and without a family history of breast cancer.
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J Clin Oncol
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1.94
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45
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Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study.
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Lancet Oncol
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2007
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1.89
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46
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Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer.
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Breast Cancer Res
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2012
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1.81
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47
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Oophorectomy after menopause and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
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Cancer Epidemiol Biomarkers Prev
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2012
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1.78
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48
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Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.
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Hum Mol Genet
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2012
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1.77
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49
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Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.
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Nat Commun
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1.73
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50
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A novel serum marker, total prostate secretory protein of 94 amino acids, improves prostate cancer detection and helps identify high grade cancers at diagnosis.
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1.71
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51
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Tumor size and survival in breast cancer--a reappraisal.
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1.70
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52
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Population based study of long-term rates of surgery for urinary incontinence after radical prostatectomy for prostate cancer.
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1.66
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53
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LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.
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Cancer Res
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2011
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1.64
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54
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A novel founder CHEK2 mutation is associated with increased prostate cancer risk.
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Cancer Res
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2004
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1.60
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55
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Early radiation exposures and BRCA1-associated breast cancer in young women from Poland.
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Breast Cancer Res Treat
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2008
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1.59
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56
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Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.
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1.57
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57
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Hereditary breast and ovarian cancer in Asia: genetic epidemiology of BRCA1 and BRCA2.
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Hum Mutat
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2002
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1.57
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58
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Coffee consumption and breast cancer risk among BRCA1 and BRCA2 mutation carriers.
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2006
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1.53
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59
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Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation.
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J Clin Oncol
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2013
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1.52
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60
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Intra-abdominal carcinomatosis after prophylactic oophorectomy in women of hereditary breast ovarian cancer syndrome kindreds associated with BRCA1 and BRCA2 mutations.
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Gynecol Oncol
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2005
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1.50
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61
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Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers.
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1.48
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62
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1.48
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63
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Breast Cancer Res Treat
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2012
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1.46
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64
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Utility of incorporating genetic variants for the early detection of prostate cancer.
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Clin Cancer Res
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1.39
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65
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Disruption of the expected positive correlation between breast tumor size and lymph node status in BRCA1-related breast carcinoma.
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2003
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1.38
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66
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Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer Consortium.
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Cancer Epidemiol Biomarkers Prev
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1.37
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67
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Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.
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1.36
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68
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A deletion in CHEK2 of 5,395 bp predisposes to breast cancer in Poland.
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Breast Cancer Res Treat
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2006
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1.34
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69
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Hereditary ovarian cancer in Poland.
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Int J Cancer
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2003
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1.30
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70
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Cancer incidence in a population of Jewish women at risk of ovarian cancer.
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J Clin Oncol
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2002
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1.27
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71
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The risk of ovarian cancer after breast cancer in BRCA1 and BRCA2 carriers.
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Gynecol Oncol
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2005
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1.27
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72
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A comparison of bilateral breast cancers in BRCA carriers.
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Cancer Epidemiol Biomarkers Prev
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1.27
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73
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1.26
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74
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The role of reexcision for positive margins in optimizing local disease control after breast-conserving surgery for cancer.
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Breast J
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2006
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1.25
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75
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Cancer variation associated with the position of the mutation in the BRCA2 gene.
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Fam Cancer
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1.25
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76
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Patterns of recurrence in the basal and non-basal subtypes of triple-negative breast cancers.
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Breast Cancer Res Treat
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2009
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1.25
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77
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Patient responses to the disclosure of BRCA mutation tests in hereditary breast-ovarian cancer families.
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Cancer Genet Cytogenet
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2006
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1.25
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78
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Time to disease recurrence in basal-type breast cancers: effects of tumor size and lymph node status.
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2009
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1.24
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79
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Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium.
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Proc Natl Acad Sci U S A
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2002
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1.23
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80
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Family history of cancer and cancer risks in women with BRCA1 or BRCA2 mutations.
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J Natl Cancer Inst
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1.21
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81
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A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer.
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Cancer Res
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2005
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1.21
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82
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Breast-cancer risk in families with mutations in PALB2.
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N Engl J Med
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1.20
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83
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RAD51C germline mutations in breast and ovarian cancer patients.
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Breast Cancer Res
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2010
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1.20
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84
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Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
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Cancer Causes Control
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2005
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1.20
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85
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Uptake of clinical genetic testing for ovarian cancer in Ontario: a population-based study.
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Gynecol Oncol
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2008
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1.19
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86
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Contribution of BRCA1 and BRCA2 mutations to breast and ovarian cancer in Pakistan.
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Am J Hum Genet
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2002
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1.17
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87
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On the origin and diffusion of BRCA1 c.5266dupC (5382insC) in European populations.
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Eur J Hum Genet
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2010
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1.17
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88
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Mammographic density and the risk of breast cancer recurrence after breast-conserving surgery.
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1.17
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89
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Single nucleotide polymorphism of the human kallikrein-2 gene highly correlates with serum human kallikrein-2 levels and in combination enhances prostate cancer detection.
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J Clin Oncol
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2003
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1.16
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90
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Familial risks of esophageal cancer among the Turkmen population of the Caspian littoral of Iran.
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Int J Cancer
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1.15
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91
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Significant proportion of breast and/or ovarian cancer families of French Canadian descent harbor 1 of 5 BRCA1 and BRCA2 mutations.
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1.14
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92
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Phenocopies in breast cancer 1 (BRCA1) families: implications for genetic counselling.
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1.14
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The risk of endometrial cancer in women with BRCA1 and BRCA2 mutations. A prospective study.
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Alcohol and risk of breast cancer.
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Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk.
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Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.
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Breast Cancer Res
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BRCA1 and pancreatic cancer: pedigree findings and their causal relationships.
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100
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Re: Survival outcomes after contralateral prophylactic mastectomy: a decision analysis.
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Significance of lymph vessel invasion identified by the endothelial lymphatic marker D2-40 in node negative breast cancer.
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Mod Pathol
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102
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BRCA1 and BRCA2 mutations among breast cancer patients from the Philippines.
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1.06
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103
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The risk of breast cancer in women with a BRCA1 mutation from North America and Poland.
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104
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Genome-wide loss of heterozygosity and uniparental disomy in BRCA1/2-associated ovarian carcinomas.
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Clin Cancer Res
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1.06
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105
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Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes.
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106
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Influence of selected lifestyle factors on breast and ovarian cancer risk in BRCA1 mutation carriers from Poland.
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107
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A high prevalence of BRCA1 mutations among breast cancer patients from the Bahamas.
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Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers.
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Breast Cancer Res
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109
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Constitutional CHEK2 mutations are associated with a decreased risk of lung and laryngeal cancers.
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The 3020insC Allele of NOD2 Predisposes to Cancers of Multiple Organs.
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Endometrial cancer risk is associated with variants of the mismatch repair genes MLH1 and MSH2.
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The obesity-associated polymorphisms FTO rs9939609 and MC4R rs17782313 and endometrial cancer risk in non-Hispanic white women.
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PLoS One
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Germline CHEK2 mutations and colorectal cancer risk: different effects of a missense and truncating mutations?
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Mutations of the MYH gene do not substantially contribute to the risk of breast cancer.
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116
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The use of genetic markers to determine risk for prostate cancer at prostate biopsy.
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Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers.
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Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers.
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ARHGDIA: a novel gene implicated in nephrotic syndrome.
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Risk of pancreatic cancer among individuals with a family history of cancer of the pancreas.
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A low selenium level is associated with lung and laryngeal cancers.
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PLoS One
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Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.
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Changes in psychosocial functioning 1 year after mastectomy alone, delayed breast reconstruction, or immediate breast reconstruction.
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Comprehensive assessment of candidate genes and serological markers for the detection of prostate cancer.
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Androgens and breast cancer.
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Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations.
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Routine TP53 testing for breast cancer under age 30: ready for prime time?
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Understanding the development of human bladder cancer by using a whole-organ genomic mapping strategy.
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Smoking and the risk of breast cancer among carriers of BRCA mutations.
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A polymorphic locus in the promoter region of the IGFBP3 gene is related to mammographic breast density.
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Variation in rates of uptake of preventive options by Canadian women carrying the BRCA1 or BRCA2 genetic mutation.
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Towards a dietary prevention of hereditary breast cancer.
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Serum insulin-like growth factor I (IGF-I) concentration in men is not associated with the cytosine-adenosine repeat polymorphism of the IGF-I gene.
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