John D Sutherland

Author PubWeight™ 30.49‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions. Nature 2009 4.49
2 Antimalarial tetranortriterpenoids from the seeds of Lansium domesticum Corr. Phytochemistry 2006 1.30
3 Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation. Nat Chem 2013 1.28
4 Prebiotic synthesis of simple sugars by photoredox systems chemistry. Nat Chem 2012 1.28
5 Direct assembly of nucleoside precursors from two- and three-carbon units. Angew Chem Int Ed Engl 2006 1.19
6 Chemoselective multicomponent one-pot assembly of purine precursors in water. J Am Chem Soc 2010 1.17
7 Towards an evolutionary theory of the origin of life based on kinetics and thermodynamics. Open Biol 2013 1.07
8 A stereoelectronic effect in prebiotic nucleotide synthesis. ACS Chem Biol 2010 1.06
9 RNA: prebiotic product, or biotic invention? Chem Biodivers 2007 1.03
10 Phosphate-mediated interconversion of ribo- and arabino-configured prebiotic nucleotide intermediates. Angew Chem Int Ed Engl 2010 0.97
11 On the prebiotic synthesis of ribonucleotides: photoanomerisation of cytosine nucleosides and nucleotides revisited. Chembiochem 2007 0.97
12 Synthesis of aldehydic ribonucleotide and amino acid precursors by photoredox chemistry. Angew Chem Int Ed Engl 2013 0.95
13 Simultaneous nucleotide activation and synthesis of amino acid amides by a potentially prebiotic multi-component reaction. Angew Chem Int Ed Engl 2007 0.91
14 Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. Chem Biodivers 2004 0.91
15 The search for a potentially prebiotic synthesis of nucleotides via arabinose-3-phosphate and its cyanamide derivative. Chemistry 2008 0.88
16 Structures of an isopenicillin N converting Ntn-hydrolase reveal different catalytic roles for the active site residues of precursor and mature enzyme. Structure 2010 0.88
17 Prebiotic chemistry: a new modus operandi. Philos Trans R Soc Lond B Biol Sci 2011 0.85
18 Expeditious, potentially primordial, aminoacylation of nucleotides. Angew Chem Int Ed Engl 2005 0.84
19 Potentially prebiotic synthesis of pyrimidine beta-D-ribonucleotides by photoanomerization/hydrolysis of alpha-D-cytidine-2'-phosphate. Chembiochem 2008 0.83
20 Formation of potentially prebiotic amphiphiles by reaction of beta-hydroxy-n-alkylamines with cyclotriphosphate. Angew Chem Int Ed Engl 2007 0.81
21 Reaction of cytidine nucleotides with cyanoacetylene: support for the intermediacy of nucleoside-2',3'-cyclic phosphates in the prebiotic synthesis of RNA. Chembiochem 2006 0.80
22 Two-step potentially prebiotic synthesis of alpha-d-cytidine-5'-phosphate from d-glyceraldehyde-3-phosphate. J Am Chem Soc 2007 0.79
23 Detection of potential TNA and RNA nucleoside precursors in a prebiotic mixture by pure shift diffusion-ordered NMR spectroscopy. Chemistry 2013 0.79
24 Conversion of biosynthetic precursors of RNA to those of DNA by photoredox chemistry. J Mol Evol 2014 0.79
25 Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 4th Communication. Further observations concerning pyrimidine nucleoside synthesis by stepwise nucleobase assembly. Chem Biodivers 2005 0.79
26 Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 2nd communication. Derivation and reactivity of xylose phosphates. Chem Biodivers 2004 0.78
27 Synthesis of cytidine ribonucleotides by stepwise assembly of the heterocycle on a sugar phosphate. Chembiochem 2003 0.78
28 Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 3rd communication. Behaviour of 5-amino-1H-imidazole-4-carbonitrile derivatives. Chem Biodivers 2004 0.77
29 Aldolisation of bis(glycolaldehyde) phosphate and formaldehyde. Chembiochem 2005 0.76
30 Purification, crystallization and preliminary X-ray diffraction of Cys103Ala acyl coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum. Acta Crystallogr D Biol Crystallogr 2002 0.76
31 An approach to prevent aggregation during the purification and crystallization of wild type acyl coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum. Protein Expr Purif 2005 0.76
32 Solid-phase synthesis and hybrization behavior of partially 2'/3'-O-acetylated RNA oligonucleotides. J Org Chem 2014 0.75
33 Substrate ambiguity and catalytic promiscuity within a bacterial proteome probed by an easy phenotypic screen for aldehydes. Angew Chem Int Ed Engl 2005 0.75