Published in J Biol Chem on March 15, 2010
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. Genetics (2012) 1.98
Packaging of fat: an evolving model of lipid droplet assembly and expansion. J Biol Chem (2011) 1.73
Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae. Annu Rev Biochem (2011) 1.51
The yeast lipin orthologue Pah1p is important for biogenesis of lipid droplets. J Cell Biol (2011) 1.51
Flexibility of a eukaryotic lipidome--insights from yeast lipidomics. PLoS One (2012) 1.26
DGK1-encoded diacylglycerol kinase activity is required for phospholipid synthesis during growth resumption from stationary phase in Saccharomyces cerevisiae. J Biol Chem (2010) 1.15
Phosphatidate phosphatase activity plays key role in protection against fatty acid-induced toxicity in yeast. J Biol Chem (2011) 1.13
Lipid droplets and peroxisomes: key players in cellular lipid homeostasis or a matter of fat--store 'em up or burn 'em down. Genetics (2013) 1.13
Phosphatidate phosphatase, a key regulator of lipid homeostasis. Biochim Biophys Acta (2012) 1.13
Arabidopsis lipins, PDAT1 acyltransferase, and SDP1 triacylglycerol lipase synergistically direct fatty acids toward β-oxidation, thereby maintaining membrane lipid homeostasis. Plant Cell (2014) 1.10
Lipid droplet autophagy in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2013) 1.09
A versatile ultra-high performance LC-MS method for lipid profiling. J Chromatogr B Analyt Technol Biomed Life Sci (2014) 1.07
Putting the pH into phosphatidic acid signaling. BMC Biol (2011) 1.05
Identification and characterization of DGA2, an acyltransferase of the DGAT1 acyl-CoA:diacylglycerol acyltransferase family in the oleaginous yeast Yarrowia lipolytica. New insights into the storage lipid metabolism of oleaginous yeasts. Appl Microbiol Biotechnol (2011) 1.03
ABI4 activates DGAT1 expression in Arabidopsis seedlings during nitrogen deficiency. Plant Physiol (2011) 1.02
Reliable Drosophila body fat quantification by a coupled colorimetric assay. PLoS One (2011) 1.00
Dual role for phospholipid:diacylglycerol acyltransferase: enhancing fatty acid synthesis and diverting fatty acids from membrane lipids to triacylglycerol in Arabidopsis leaves. Plant Cell (2013) 0.99
Coordination of storage lipid synthesis and membrane biogenesis: evidence for cross-talk between triacylglycerol metabolism and phosphatidylinositol synthesis. J Biol Chem (2010) 0.95
Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast. Yeast (2012) 0.95
Integration of peroxisomes into an endomembrane system that governs cellular aging. Front Physiol (2012) 0.93
The emergence of lipid droplets in yeast: current status and experimental approaches. Curr Genet (2013) 0.90
A conserved family of proteins facilitates nascent lipid droplet budding from the ER. J Cell Biol (2015) 0.88
SCS3 and YFT2 link transcription of phospholipid biosynthetic genes to ER stress and the UPR. PLoS Genet (2012) 0.87
The central clock neurons regulate lipid storage in Drosophila. PLoS One (2011) 0.86
Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae. PLoS One (2013) 0.86
Morphogenesis checkpoint kinase Swe1 is the executor of lipolysis-dependent cell-cycle progression. Proc Natl Acad Sci U S A (2015) 0.85
The response to inositol: regulation of glycerolipid metabolism and stress response signaling in yeast. Chem Phys Lipids (2014) 0.85
PAH1-encoded phosphatidate phosphatase plays a role in the growth phase- and inositol-mediated regulation of lipid synthesis in Saccharomyces cerevisiae. J Biol Chem (2013) 0.84
Lipid droplet-mediated ER homeostasis regulates autophagy and cell survival during starvation. J Cell Biol (2016) 0.84
Controlling lipid fluxes at glycerol-3-phosphate acyltransferase step in yeast: unique contribution of Gat1p to oleic acid-induced lipid particle formation. J Biol Chem (2012) 0.83
Increase of eicosapentaenoic acid in thraustochytrids through thraustochytrid ubiquitin promoter-driven expression of a fatty acid {delta}5 desaturase gene. Appl Environ Microbiol (2011) 0.82
Involvement of the Saccharomyces cerevisiae hydrolase Ldh1p in lipid homeostasis. Eukaryot Cell (2011) 0.82
TORC1 regulates Pah1 phosphatidate phosphatase activity via the Nem1/Spo7 protein phosphatase complex. PLoS One (2014) 0.81
Ectopic Expression of WRINKLED1 Affects Fatty Acid Homeostasis in Brachypodium distachyon Vegetative Tissues. Plant Physiol (2015) 0.79
Lipids and cell death in yeast. FEMS Yeast Res (2013) 0.79
Lipids as conductors in the orchestra of life. F1000 Biol Rep (2012) 0.78
The Relationship of Triacylglycerol and Starch Accumulation to Carbon and Energy Flows during Nutrient Deprivation in Chlamydomonas reinhardtii. Plant Physiol (2016) 0.77
Lipid Droplets Form from Distinct Regions of the Cell in the Fission Yeast Schizosaccharomyces pombe. Traffic (2016) 0.77
Experimental and computational analysis of a large protein network that controls fat storage reveals the design principles of a signaling network. PLoS Comput Biol (2015) 0.76
Lipid droplets maintain lipid homeostasis during anaphase for efficient cell separation in budding yeast. Mol Biol Cell (2016) 0.76
Transcription factor Reb1p regulates DGK1-encoded diacylglycerol kinase and lipid metabolism in Saccharomyces cerevisiae. J Biol Chem (2013) 0.76
Nitrogen deficiency system is helpful in characterizing regulation mechanisms of ectopic triacylglycerol accumulation in Arabidopsis seedlings. Plant Signal Behav (2011) 0.75
The Phospholipid:Diacylglycerol Acyltransferase Lro1 Is Responsible for Hepatitis C Virus Core-Induced Lipid Droplet Formation in a Yeast Model System. PLoS One (2016) 0.75
Lipidomics-Reshaping the Analysis and Perception of Type 2 Diabetes. Int J Mol Sci (2016) 0.75
C1 Metabolism Inhibition and Nitrogen Deprivation Trigger Triacylglycerol Accumulation in Arabidopsis thaliana Cell Cultures and Highlight a Role of NPC in Phosphatidylcholine-to-Triacylglycerol Pathway. Front Plant Sci (2017) 0.75
Cloning and functional analysis of three diacylglycerol acyltransferase genes from peanut (Arachis hypogaea L.). PLoS One (2014) 0.75
The slim, the fat, and the obese: guess who lives the longest? Curr Genet (2016) 0.75
Global analysis of protein localization in budding yeast. Nature (2003) 33.22
Triglyceride accumulation protects against fatty acid-induced lipotoxicity. Proc Natl Acad Sci U S A (2003) 6.46
Functional genomic screen reveals genes involved in lipid-droplet formation and utilization. Nature (2008) 4.70
Lipid droplets finally get a little R-E-S-P-E-C-T. Cell (2009) 4.58
The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme. J Biol Chem (2006) 4.37
The lipodystrophy protein seipin is found at endoplasmic reticulum lipid droplet junctions and is important for droplet morphology. Proc Natl Acad Sci U S A (2007) 3.11
The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth. EMBO J (2005) 3.02
Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast. J Cell Biol (2008) 2.85
The life of lipid droplets. Biochim Biophys Acta (2008) 2.75
Adoption of PERILIPIN as a unifying nomenclature for the mammalian PAT-family of intracellular lipid storage droplet proteins. J Lipid Res (2009) 2.55
Cdk1/Cdc28-dependent activation of the major triacylglycerol lipase Tgl4 in yeast links lipolysis to cell-cycle progression. Mol Cell (2009) 2.46
Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiae. J Bacteriol (1999) 2.31
Intracellular lipid particles of eukaryotic cells. Biochim Biophys Acta (2000) 2.28
The DGA1 gene determines a second triglyceride synthetic pathway in yeast. J Biol Chem (2001) 2.22
Obese yeast: triglyceride lipolysis is functionally conserved from mammals to yeast. J Biol Chem (2005) 2.11
The gregarious lipid droplet. J Biol Chem (2008) 2.10
A lecithin cholesterol acyltransferase-like gene mediates diacylglycerol esterification in yeast. J Biol Chem (2000) 2.04
Roles of phosphatidate phosphatase enzymes in lipid metabolism. Trends Biochem Sci (2006) 2.03
Control of phospholipid synthesis by phosphorylation of the yeast lipin Pah1p/Smp2p Mg2+-dependent phosphatidate phosphatase. J Biol Chem (2006) 1.99
Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome. Mol Microbiol (2004) 1.90
Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism. J Biol Chem (1993) 1.86
As a matter of fat. Cell Metab (2009) 1.85
The cellular functions of the yeast lipin homolog PAH1p are dependent on its phosphatidate phosphatase activity. J Biol Chem (2007) 1.68
Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2. J Biol Chem (2008) 1.68
Synthesis of triacylglycerols by the acyl-coenzyme A:diacyl-glycerol acyltransferase Dga1p in lipid particles of the yeast Saccharomyces cerevisiae. J Bacteriol (2002) 1.66
Synthesis, storage and degradation of neutral lipids in yeast. Biochim Biophys Acta (2006) 1.64
The life cycle of neutral lipids: synthesis, storage and degradation. Cell Mol Life Sci (2006) 1.47
The spatial organization of lipid synthesis in the yeast Saccharomyces cerevisiae derived from large scale green fluorescent protein tagging and high resolution microscopy. Mol Cell Proteomics (2005) 1.38
The lipin family: mutations and metabolism. Curr Opin Lipidol (2009) 1.35
Dual localization of squalene epoxidase, Erg1p, in yeast reflects a relationship between the endoplasmic reticulum and lipid particles. Mol Biol Cell (1998) 1.35
Yeast acyl-CoA synthetases at the crossroads of fatty acid metabolism and regulation. Biochim Biophys Acta (2006) 1.34
Good fat, essential cellular requirements for triacylglycerol synthesis to maintain membrane homeostasis in yeast. J Biol Chem (2009) 1.34
Structural and biochemical properties of lipid particles from the yeast Saccharomyces cerevisiae. J Biol Chem (2008) 1.31
Synthesis and turnover of non-polar lipids in yeast. Prog Lipid Res (2008) 1.27
Janus-faced enzymes yeast Tgl3p and Tgl5p catalyze lipase and acyltransferase reactions. Mol Biol Cell (2009) 1.19
Sterol and diacylglycerol acyltransferase deficiency triggers fatty acid-mediated cell death. J Biol Chem (2009) 1.16
Ypr140wp, 'the yeast tafazzin', displays a mitochondrial lysophosphatidylcholine (lyso-PC) acyltransferase activity related to triacylglycerol and mitochondrial lipid synthesis. Biochem J (2005) 1.15
Inhibition of acetyl coenzyme A carboxylase activity restores expression of the INO1 gene in a snf1 mutant strain of Saccharomyces cerevisiae. Mol Cell Biol (2001) 1.15
Comparative biochemical studies of the murine fatty acid transport proteins (FATP) expressed in yeast. J Biol Chem (2005) 1.15
A block in endoplasmic reticulum-to-Golgi trafficking inhibits phospholipid synthesis and induces neutral lipid accumulation. J Biol Chem (2008) 1.11
Cell biology. Great balls of fat. Science (2006) 1.10
Dynamics of neutral lipid storage and mobilization in yeast. Biochimie (2006) 1.03
Quantitative modeling of triacylglycerol homeostasis in yeast--metabolic requirement for lipolysis to promote membrane lipid synthesis and cellular growth. FEBS J (2008) 0.99
Targeting of proteins involved in sterol biosynthesis to lipid particles of the yeast Saccharomyces cerevisiae. Biochim Biophys Acta (2004) 0.95
Identification of genes affecting lipid content using transposon mutagenesis in Saccharomyces cerevisiae. Biosci Biotechnol Biochem (2006) 0.90
Obese and anorexic yeasts: experimental models to understand the metabolic syndrome and lipotoxicity. Biochim Biophys Acta (2010) 0.89
Glycerol-3-phosphate acyltransferases gat1p and gat2p are microsomal phosphoproteins with differential contributions to polarized cell growth. Eukaryot Cell (2009) 0.88
SLipid-induced cell dysfunction and cell death: lessons from yeast. Curr Hypertens Rep (2007) 0.88
Lipid storage and mobilization pathways in yeast. Novartis Found Symp (2007) 0.78