Angela M Gronenborn

Author PubWeight™ 129.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams. 1991. J Magn Reson 2011 3.69
2 Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics. Nature 2013 2.98
3 Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism. Nat Struct Mol Biol 2009 2.77
4 Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G. Nucleic Acids Res 2007 2.49
5 Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function. Cell 2009 2.32
6 HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1. J Biol Chem 2012 1.86
7 Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection. J Biol Chem 2013 1.76
8 Insights into equilibrium dynamics of proteins from comparison of NMR and X-ray data with computational predictions. Structure 2007 1.66
9 Structural basis of the anti-HIV activity of the cyanobacterial Oscillatoria Agardhii agglutinin. Structure 2011 1.57
10 HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation. J Biol Chem 2010 1.49
11 Mechanism of allosteric activation of SAMHD1 by dGTP. Nat Struct Mol Biol 2013 1.49
12 Solid-state NMR studies of HIV-1 capsid protein assemblies. J Am Chem Soc 2010 1.49
13 Novel 2D triple-resonance NMR experiments for sequential resonance assignments of proteins. J Magn Reson 2002 1.43
14 The structure of a replication initiator unites diverse aspects of nucleic acid metabolism. Proc Natl Acad Sci U S A 2002 1.41
15 A solution NMR study of the binding kinetics and the internal dynamics of an HIV-1 protease-substrate complex. Protein Sci 2003 1.39
16 The domain-swapped dimer of cyanovirin-N is in a metastable folded state: reconciliation of X-ray and NMR structures. Structure 2002 1.37
17 NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity. Nat Commun 2013 1.36
18 Multisite and multivalent binding between cyanovirin-N and branched oligomannosides: calorimetric and NMR characterization. Chem Biol 2002 1.32
19 Cyanovirin-N binds to the viral surface glycoprotein, GP1,2 and inhibits infectivity of Ebola virus. Antiviral Res 2003 1.29
20 Motions on the millisecond time scale and multiple conformations of HIV-1 capsid protein: implications for structural polymorphism of CA assemblies. J Am Chem Soc 2012 1.28
21 Solution structure of the mature HIV-1 protease monomer: insight into the tertiary fold and stability of a precursor. J Biol Chem 2003 1.25
22 The structure of the cataract-causing P23T mutant of human gammaD-crystallin exhibits distinctive local conformational and dynamic changes. Biochemistry 2009 1.25
23 The highly specific carbohydrate-binding protein cyanovirin-N: structure, anti-HIV/Ebola activity and possibilities for therapy. Mini Rev Med Chem 2005 1.24
24 The solution NMR structure of Antheraea polyphemus PBP provides new insight into pheromone recognition by pheromone-binding proteins. J Mol Biol 2004 1.20
25 Posttranscriptional activation of the transcriptional activator Rob by dipyridyl in Escherichia coli. J Bacteriol 2002 1.19
26 Dissecting carbohydrate-Cyanovirin-N binding by structure-guided mutagenesis: functional implications for viral entry inhibition. Protein Eng Des Sel 2006 1.19
27 Core mutations switch monomeric protein GB1 into an intertwined tetramer. Nat Struct Biol 2002 1.16
28 Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces. PLoS Pathog 2011 1.15
29 1H-13C/1H-15N heteronuclear dipolar recoupling by R-symmetry sequences under fast magic angle spinning for dynamics analysis of biological and organic solids. J Am Chem Soc 2011 1.14
30 Spin diffusion driven by R-symmetry sequences: applications to homonuclear correlation spectroscopy in MAS NMR of biological and organic solids. J Am Chem Soc 2011 1.13
31 Solution and crystal structures of a sugar binding site mutant of cyanovirin-N: no evidence of domain swapping. Structure 2008 1.13
32 Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67. Nat Struct Mol Biol 2005 1.11
33 Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Mol Biol Cell 2010 1.10
34 Effective lattice behavior of fluorescence energy transfer at lamellar macromolecular interfaces. Biophys J 2002 1.09
35 In support of the BMRB. Nat Struct Mol Biol 2012 1.09
36 A protein contortionist: core mutations of GB1 that induce dimerization and domain swapping. J Mol Biol 2003 1.09
37 Insight into the structural basis of pro- and antiapoptotic p53 modulation by ASPP proteins. J Biol Chem 2009 1.09
38 Sensitivity-enhanced 2D IPAP, TROSY-anti-TROSY, and E.COSY experiments: alternatives for measuring dipolar 15N-1HN couplings. J Magn Reson 2003 1.08
39 A short recollection on the paper entitled "A common sense approach to peak picking in two-, three-, and four-dimensional spectra using automatic computer analysis of contour diagrams" by D.S. Garrett, R. Powers, A.M. Gronenborn, and G.M. Clore [J. Magn. Reson. 95 (1991) 214-220]. J Magn Reson 2011 1.08
40 Protease cleavage leads to formation of mature trimer interface in HIV-1 capsid. PLoS Pathog 2012 1.07
41 Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects. Retrovirology 2012 1.06
42 HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain. Proc Natl Acad Sci U S A 2009 1.06
43 Novel fold and carbohydrate specificity of the potent anti-HIV cyanobacterial lectin from Oscillatoria agardhii. J Biol Chem 2010 1.06
44 Determination of relative tensor orientations by γ-encoded chemical shift anisotropy/heteronuclear dipolar coupling 3D NMR spectroscopy in biological solids. Phys Chem Chem Phys 2010 1.05
45 The evolutionarily conserved family of cyanovirin-N homologs: structures and carbohydrate specificity. Structure 2008 1.04
46 Structural insight into HIV-1 capsid recognition by rhesus TRIM5α. Proc Natl Acad Sci U S A 2012 1.03
47 Solution structure, divalent metal and DNA binding of the endonuclease domain from the replication initiation protein from porcine circovirus 2. J Mol Biol 2007 1.02
48 Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties. Nucleic Acids Res 2013 1.01
49 Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization. J Biol Chem 2010 1.01
50 Revisiting monomeric HIV-1 protease. Characterization and redesign for improved properties. J Biol Chem 2002 1.01
51 Structural consequences of the pH-induced conformational switch in A.polyphemus pheromone-binding protein: mechanisms of ligand release. J Mol Biol 2005 1.01
52 Versatility of the carboxy-terminal domain of the alpha subunit of RNA polymerase in transcriptional activation: use of the DNA contact site as a protein contact site for MarA. Mol Microbiol 2004 1.00
53 Recoupling of chemical shift anisotropy by R-symmetry sequences in magic angle spinning NMR spectroscopy. J Chem Phys 2012 1.00
54 Magic angle spinning NMR reveals sequence-dependent structural plasticity, dynamics, and the spacer peptide 1 conformation in HIV-1 capsid protein assemblies. J Am Chem Soc 2013 0.99
55 Cyclopentenone prostaglandin-induced unfolding and aggregation of the Parkinson disease-associated UCH-L1. Proc Natl Acad Sci U S A 2010 0.99
56 Insights into conformation and dynamics of protein GB1 during folding and unfolding by NMR. J Mol Biol 2004 0.99
57 Nanosecond relaxation dynamics of protein GB1 identified by the time-dependent red shift in the fluorescence of tryptophan and 5-fluorotryptophan. J Phys Chem B 2006 0.98
58 Flipping the switch from monomeric to dimeric CV-N has little effect on antiviral activity. Structure 2004 0.97
59 Structure-function analysis of a CVNH-LysM lectin expressed during plant infection by the rice blast fungus Magnaporthe oryzae. Structure 2011 0.97
60 The domain-swapped dimer of cyanovirin-N contains two sets of oligosaccharide binding sites in solution. Biochem Biophys Res Commun 2002 0.95
61 NMR studies on domain diffusion and alignment in modular GB1 repeats. Biophys J 2010 0.95
62 Filtering and selection of structural models: combining docking and NMR. Proteins 2003 0.94
63 Kinetically competing huntingtin aggregation pathways control amyloid polymorphism and properties. Biochemistry 2012 0.94
64 Structural insights into the anti-HIV activity of the Oscillatoria agardhii agglutinin homolog lectin family. J Biol Chem 2012 0.94
65 Protein Backbone 1H(N)-13Calpha and 15N-13Calpha residual dipolar and J couplings: new constraints for NMR structure determination. J Am Chem Soc 2004 0.94
66 A captured folding intermediate involved in dimerization and domain-swapping of GB1. J Mol Biol 2004 0.93
67 APOBEC2 is a monomer in solution: implications for APOBEC3G models. Biochemistry 2012 0.93
68 Determination of multicomponent protein structures in solution using global orientation and shape restraints. J Am Chem Soc 2009 0.93
69 Multivalent glyconanoparticles with enhanced affinity to the anti-viral lectin Cyanovirin-N. Chem Commun (Camb) 2011 0.92
70 Solution structure of the endonuclease domain from the master replication initiator protein of the nanovirus faba bean necrotic yellows virus and comparison with the corresponding geminivirus and circovirus structures. Biochemistry 2007 0.92
71 The phox domain of sorting nexin 5 lacks phosphatidylinositol 3-phosphate (PtdIns(3)P) specificity and preferentially binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). J Biol Chem 2009 0.92
72 Domain swapping proceeds via complete unfolding: a 19F- and 1H-NMR study of the Cyanovirin-N protein. J Am Chem Soc 2012 0.92
73 Solid-state NMR spectroscopy of protein complexes. Methods Mol Biol 2012 0.91
74 The Cullin-RING E3 ubiquitin ligase CRL4-DCAF1 complex dimerizes via a short helical region in DCAF1. Biochemistry 2011 0.91
75 Atomic mapping of the interactions between the antiviral agent cyanovirin-N and oligomannosides by saturation-transfer difference NMR. Biochemistry 2004 0.91
76 Functional homologs of cyanovirin-N amenable to mass production in prokaryotic and eukaryotic hosts. Protein Expr Purif 2002 0.91
77 Structural and biochemical characterization of the childhood cataract-associated R76S mutant of human γD-crystallin. Biochemistry 2012 0.90
78 Atomic mapping of the sugar interactions in one-site and two-site mutants of cyanovirin-N by NMR spectroscopy. Biochemistry 2008 0.90
79 Direct measurement of glyconanoparticles and lectin interactions by isothermal titration calorimetry. Anal Chem 2012 0.89
80 Placement of 19F into the center of GB1: effects on structure and stability. FEBS Lett 2002 0.89
81 The GB1 amyloid fibril: recruitment of the peripheral beta-strands of the domain swapped dimer into the polymeric interface. J Mol Biol 2005 0.89
82 A comparative analysis of the equilibrium dynamics of a designed protein inferred from NMR, X-ray, and computations. Proteins 2009 0.89
83 Evaluating the strength of salt bridges: a comparison of current biomolecular force fields. J Phys Chem B 2014 0.88
84 The human W42R γD-crystallin mutant structure provides a link between congenital and age-related cataracts. J Biol Chem 2012 0.87
85 A designed chimeric cyanovirin-N homolog lectin: structure and molecular basis of sucrose binding. Proteins 2009 0.86
86 1H, 15N and 13C assignments of the dimeric C-terminal domain of HIV-1 capsid protein. Biomol NMR Assign 2009 0.85
87 Structure, dynamics, and Hck interaction of full-length HIV-1 Nef. Proteins 2011 0.85
88 The p66 immature precursor of HIV-1 reverse transcriptase. Proteins 2014 0.84
89 The point mutation A34F causes dimerization of GB1. Proteins 2008 0.84
90 Longer simulations sample larger subspaces of conformations while maintaining robust mechanisms of motion. Proteins 2011 0.83
91 Allosteric communication between cAMP binding sites in the RI subunit of protein kinase A revealed by NMR. J Biol Chem 2010 0.83
92 Hydrophobic interactions at the Ccap position of the C-capping motif of alpha-helices. J Mol Biol 2002 0.83
93 Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity. Biochemistry 2016 0.82
94 Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates. Proc Natl Acad Sci U S A 2013 0.82
95 Characterization of specific protein association by 15N CPMG relaxation dispersion NMR: the GB1(A34F) monomer-dimer equilibrium. J Phys Chem B 2007 0.82
96 NMR solution structure of a cyanovirin homolog from wheat head blight fungus. Proteins 2011 0.82
97 Elimination of the C-cap in ubiquitin - structure, dynamics and thermodynamic consequences. Biophys Chem 2006 0.82
98 Sensing lectin-glycan interactions using lectin super-microarrays and glycans labeled with dye-doped silica nanoparticles. Biosens Bioelectron 2013 0.82
99 Burkholderia oklahomensis agglutinin is a canonical two-domain OAA-family lectin: structures, carbohydrate binding and anti-HIV activity. FEBS J 2013 0.82
100 A NMR guided approach for CsrA-RNA crystallization. J Biomol NMR 2013 0.82
101 Solution structure of a circular-permuted variant of the potent HIV-inactivating protein cyanovirin-N: structural basis for protein stability and oligosaccharide interaction. J Mol Biol 2003 0.81
102 Sequence and structural determinants of human APOBEC3H deaminase and anti-HIV-1 activities. Retrovirology 2015 0.80
103 Cyanovirin-N binding to Manalpha1-2Man functionalized dendrimers. Org Biomol Chem 2005 0.80
104 Crystal structure of the cataract-causing P23T γD-crystallin mutant. Proteins 2013 0.80
105 The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro. Retrovirology 2010 0.79
106 Design and initial characterization of a circular permuted variant of the potent HIV-inactivating protein cyanovirin-N. Proteins 2002 0.79
107 Structural and binding studies of the C-terminal domains of yeast TFIIF subunits Tfg1 and Tfg2. Proteins 2011 0.79
108 Enhanced accuracy of kinetic information from CT-CPMG experiments by transverse rotating-frame spectroscopy. J Biomol NMR 2013 0.78
109 1H, 13C, and 15N NMR assignment of the master Rep protein nuclease domain from the nanovirus FBNYV. J Biomol NMR 2006 0.78
110 The regulatory subunit of PKA-I remains partially structured and undergoes β-aggregation upon thermal denaturation. PLoS One 2011 0.78
111 Sensitivity-enhanced IPAP experiments for measuring one-bond 13C'-13Calpha and 13Calpha-1Halpha residual dipolar couplings in proteins. J Magn Reson 2004 0.78
112 Weak protein complexes: challenging to study but essential for life. FEBS J 2014 0.78
113 Binding of HIV-1 Vpr protein to the human homolog of the yeast DNA repair protein RAD23 (hHR23A) requires its xeroderma pigmentosum complementation group C binding (XPCB) domain as well as the ubiquitin-associated 2 (UBA2) domain. J Biol Chem 2013 0.78
114 Expression and purification of human tryptophan hydroxylase from Escherichia coli and Pichia pastoris. Protein Expr Purif 2004 0.77
115 1H, 13C, and 15N assignment of the N-terminal, catalytic domain of the replication initiation protein from the geminivirus TYLCV. J Biomol NMR 2002 0.77
116 Fluorinated carbohydrates as lectin ligands: dissecting glycan-cyanovirin interactions by using 19F NMR spectroscopy. Chemistry 2013 0.77
117 Dynamic Nuclear Polarization Enhanced MAS NMR Spectroscopy for Structural Analysis of HIV-1 Protein Assemblies. J Phys Chem B 2016 0.77
118 Sweet entanglements--protein:glycan interactions in two HIV-inactivating lectin families. Biopolymers 2012 0.76
119 Unified biogenesis of ambiguine, fischerindole, hapalindole and welwitindolinone: identification of a monogeranylated indolenine as a cryptic common biosynthetic intermediate by an unusual magnesium-dependent aromatic prenyltransferase. Chem Commun (Camb) 2016 0.76
120 Solution structure and dynamics of the human-Escherichia coli thioredoxin chimera: insights into thermodynamic stability. Biochemistry 2002 0.75
121 Excluded volume effect within the continuous model for the fluorescence energy transfer. Biophys J 2002 0.75
122 HIV-1 Capsid Function is Regulated by Dynamics: Quantitative Atomic-Resolution Insights by Integrating Magic-Angle-Spinning NMR, QM/MM, and MD. J Am Chem Soc 2016 0.75
123 Sensitivity-enhanced E.COSY-type HSQC experiments for accurate measurements of one-bond 15N-1H(N) and 15N-13C' and two-bond 13C'-1H(N) residual dipolar couplings in proteins. J Magn Reson 2002 0.75
124 Direct Observation of Carbohydrate Hydroxyl Protons in Hydrogen Bonds with a Protein. J Am Chem Soc 2017 0.75
125 Assessment of solvent effects: do weak alignment media affect the structure of the solute? Magn Reson Chem 2007 0.75
126 Simultaneous and accurate determination of one-bond (15)N-(13)C' and two-bond (1)H(N)--(13)C' dipolar couplings. J Am Chem Soc 2003 0.75