PubRank

Howard J Edenberg

Author PubWeight™ 212.42‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet 2013 8.02
2 Variants in nicotinic receptors and risk for nicotine dependence. Am J Psychiatry 2008 6.73
3 A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A 2010 4.94
4 Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol 2010 4.83
5 Effects of filtering by Present call on analysis of microarray experiments. BMC Bioinformatics 2006 3.86
6 Splicing factor SFRS1 recognizes a functionally diverse landscape of RNA transcripts. Genome Res 2008 3.33
7 Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet 2005 3.24
8 Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet 2003 3.02
9 Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A 2002 2.47
10 Evidence of common and specific genetic effects: association of the muscarinic acetylcholine receptor M2 (CHRM2) gene with alcohol dependence and major depressive syndrome. Hum Mol Genet 2004 2.47
11 Changes in gene expression during pegylated interferon and ribavirin therapy of chronic hepatitis C virus distinguish responders from nonresponders to antiviral therapy. J Virol 2007 2.45
12 Murine embryonic stem cell differentiation is promoted by SOCS-3 and inhibited by the zinc finger transcription factor Klf4. Blood 2004 2.35
13 The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across developmental stages. Behav Genet 2006 2.26
14 Linkage and linkage disequilibrium mapping of ERP and EEG phenotypes. Biol Psychol 2002 2.08
15 Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A 2011 2.01
16 Global effect of PEG-IFN-alpha and ribavirin on gene expression in PBMC in vitro. J Interferon Cytokine Res 2004 1.98
17 A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. Am J Med Genet A 2004 1.88
18 A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence. Biol Psychiatry 2008 1.88
19 Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behav Genet 2006 1.87
20 Linkage and linkage disequilibrium of evoked EEG oscillations with CHRM2 receptor gene polymorphisms: implications for human brain dynamics and cognition. Int J Psychophysiol 2004 1.79
21 Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychol Sci 2010 1.78
22 Reproducibility of oligonucleotide arrays using small samples. BMC Genomics 2003 1.75
23 Using dimensional models of externalizing psychopathology to aid in gene identification. Arch Gen Psychiatry 2008 1.73
24 Differential gene induction by type I and type II interferons and their combination. J Interferon Cytokine Res 2006 1.61
25 A new statistic to evaluate imputation reliability. PLoS One 2010 1.50
26 Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. Alcohol Clin Exp Res 2012 1.50
27 Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. Am J Hum Genet 2005 1.49
28 Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees. Biol Psychiatry 2003 1.49
29 Coordinate repression of regulators of embryonic identity by PICKLE during germination in Arabidopsis. Plant J 2003 1.49
30 Association of GABA(A) receptors and alcohol dependence and the effects of genetic imprinting. Am J Med Genet B Neuropsychiatr Genet 2003 1.47
31 Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. Alcohol Clin Exp Res 2007 1.47
32 Linkage mapping of beta 2 EEG waves via non-parametric regression. Am J Med Genet B Neuropsychiatr Genet 2003 1.45
33 An evaluation of the full level of response to alcohol model of heavy drinking and problems in COGA offspring. J Stud Alcohol Drugs 2009 1.41
34 Alcohol dependence with comorbid drug dependence: genetic and phenotypic associations suggest a more severe form of the disorder with stronger genetic contribution to risk. Addiction 2007 1.40
35 Differential gene expression in the nucleus accumbens with ethanol self-administration in inbred alcohol-preferring rats. Pharmacol Biochem Behav 2008 1.39
36 Association between GABRA1 and drinking behaviors in the collaborative study on the genetics of alcoholism sample. Alcohol Clin Exp Res 2006 1.39
37 Isolation of mRNA from specific tissues of Drosophila by mRNA tagging. Nucleic Acids Res 2005 1.34
38 Association of alcohol craving with alpha-synuclein (SNCA). Alcohol Clin Exp Res 2007 1.33
39 Genome-wide association study of bone mineral density in premenopausal European-American women and replication in African-American women. J Clin Endocrinol Metab 2010 1.30
40 Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. Alcohol Clin Exp Res 2002 1.29
41 Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. Alcohol Clin Exp Res 2007 1.29
42 Association of GABRG3 with alcohol dependence. Alcohol Clin Exp Res 2004 1.28
43 Functional gene expression differences between inbred alcohol-preferring and -non-preferring rats in five brain regions. Alcohol 2007 1.28
44 POZ domain transcription factor, FBI-1, represses transcription of ADH5/FDH by interacting with the zinc finger and interfering with DNA binding activity of Sp1. J Biol Chem 2002 1.27
45 Teenagers are right--parents do not know much: an analysis of adolescent-parent agreement on reports of adolescent substance use, abuse, and dependence. Alcohol Clin Exp Res 2006 1.26
46 Contribution of the LRP5 gene to normal variation in peak BMD in women. J Bone Miner Res 2004 1.26
47 Global transcriptional profiling demonstrates the combination of type I and type II interferon enhances antiviral and immune responses at clinically relevant doses. J Interferon Cytokine Res 2005 1.26
48 Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample. Drug Alcohol Depend 2007 1.23
49 Genome-wide association of bipolar disorder suggests an enrichment of replicable associations in regions near genes. PLoS Genet 2011 1.23
50 The CHD3 remodeler PICKLE promotes trimethylation of histone H3 lysine 27. J Biol Chem 2008 1.22
51 Epigenetics of gene expression in human hepatoma cells: expression profiling the response to inhibition of DNA methylation and histone deacetylation. BMC Genomics 2006 1.20
52 Integration of general amino acid control and target of rapamycin (TOR) regulatory pathways in nitrogen assimilation in yeast. J Biol Chem 2010 1.20
53 Gene expression changes in the nucleus accumbens of alcohol-preferring rats following chronic ethanol consumption. Pharmacol Biochem Behav 2009 1.17
54 Meta-analysis of genome-wide studies identifies WNT16 and ESR1 SNPs associated with bone mineral density in premenopausal women. J Bone Miner Res 2013 1.16
55 Drosophila homer is required in a small set of neurons including the ellipsoid body for normal ethanol sensitivity and tolerance. J Neurosci 2007 1.15
56 The opioid system in alcohol and drug dependence: family-based association study. Am J Med Genet B Neuropsychiatr Genet 2007 1.14
57 CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results. Addiction 2012 1.14
58 Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. Am J Med Genet B Neuropsychiatr Genet 2009 1.12
59 A genome-wide association study of DSM-IV cannabis dependence. Addict Biol 2010 1.12
60 Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment. J Transl Med 2008 1.11
61 Predictors of sexual debut at age 16 or younger. Arch Sex Behav 2008 1.11
62 A cholinergic receptor gene (CHRM2) affects event-related oscillations. Behav Genet 2006 1.09
63 Genes encoding enzymes involved in ethanol metabolism. Alcohol Res 2012 1.09
64 Alteration of gene expression by alcohol exposure at early neurulation. BMC Genomics 2011 1.08
65 Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers. Arch Gen Psychiatry 2012 1.08
66 The tachykinin receptor 3 is associated with alcohol and cocaine dependence. Alcohol Clin Exp Res 2008 1.08
67 Loss of metabotropic glutamate receptor 2 escalates alcohol consumption. Proc Natl Acad Sci U S A 2013 1.07
68 Gene expression profiling of Caco-2 BBe cells suggests a role for specific signaling pathways during intestinal differentiation. Physiol Genomics 2003 1.07
69 The prognostic implications of DSM-IV abuse criteria in drinking adolescents. Drug Alcohol Depend 2008 1.06
70 Augmentation of UVB radiation-mediated early gene expression by the epidermal platelet-activating factor receptor. J Invest Dermatol 2007 1.06
71 A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks. Hum Genet 2013 1.06
72 Pharmacogenetics of alcohol and alcohol dependence treatment. Curr Pharm Des 2010 1.05
73 Effects of glucose metabolism on the regulation of genes of fatty acid synthesis and triglyceride secretion in the liver. J Lipid Res 2007 1.05
74 Laboratory methods for high-throughput genotyping. Cold Spring Harb Protoc 2009 1.04
75 Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence. Alcohol Clin Exp Res 2008 1.04
76 Global effects of vitamin A deficiency on gene expression in rat liver: evidence for hypoandrogenism. J Nutr Biochem 2005 1.04
77 A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers. Oncotarget 2010 1.03
78 Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. Am J Med Genet B Neuropsychiatr Genet 2010 1.03
79 Model-based identification of cis-acting elements from microarray data. Genomics 2006 1.03
80 Alternative splicing and promoter use in the human GABRA2 gene. Brain Res Mol Brain Res 2005 1.03
81 Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome. BMC Genomics 2008 1.02
82 The AVPR1A gene and substance use disorders: association, replication, and functional evidence. Biol Psychiatry 2011 1.02
83 Changes in gene expression in regions of the extended amygdala of alcohol-preferring rats after binge-like alcohol drinking. Alcohol 2010 1.02
84 Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. Am J Med Genet B Neuropsychiatr Genet 2010 1.01
85 Influence of ADH1B polymorphism on alcohol use and its subjective effects in a Jewish population. Am J Med Genet 2002 1.01
86 Human ALOX12, but not ALOX15, is associated with BMD in white men and women. J Bone Miner Res 2006 1.00
87 Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. Am J Clin Nutr 2012 0.99
88 Association of CHRM2 with IQ: converging evidence for a gene influencing intelligence. Behav Genet 2006 0.99
89 Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. Alcohol Clin Exp Res 2010 0.99
90 Alcohol criteria endorsement and psychiatric and drug use disorders among DUI offenders: greater severity among women and multiple offenders. Addict Behav 2008 0.98
91 Evidence of association between brain-derived neurotrophic factor gene and bipolar disorder. Psychiatr Genet 2008 0.97
92 Alt Event Finder: a tool for extracting alternative splicing events from RNA-seq data. BMC Genomics 2012 0.96
93 No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample. Am J Med Genet B Neuropsychiatr Genet 2005 0.96
94 Candidate genes for alcohol preference identified by expression profiling in alcohol-preferring and -nonpreferring reciprocal congenic rats. Genome Biol 2010 0.96
95 Natural haplotypes in the regulatory sequences affect human alcohol dehydrogenase 1C (ADH1C) gene expression. Hum Mutat 2005 0.95
96 Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcohol Clin Exp Res 2014 0.95
97 Association of alcohol dehydrogenase genes with alcohol-related phenotypes in a Native American community sample. Alcohol Clin Exp Res 2011 0.95
98 Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. Addict Biol 2013 0.95
99 Identification of candidate genes for alcohol preference by expression profiling of congenic rat strains. Alcohol Clin Exp Res 2007 0.95
100 A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9. Biol Psychiatry 2007 0.95
101 Chronic alcohol exposure alters gene expression in HepG2 cells. Alcohol Clin Exp Res 2011 0.95
102 A proline-threonine substitution in codon 351 of ADH1C is common in Native Americans. Alcohol Clin Exp Res 2002 0.94
103 Toxoplasma gondii lysine acetyltransferase GCN5-A functions in the cellular response to alkaline stress and expression of cyst genes. PLoS Pathog 2010 0.94
104 Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm. PLoS One 2009 0.94
105 Multiple-domain predictors of problematic alcohol use in young adulthood. J Stud Alcohol Drugs 2008 0.92
106 Apparent replication of suggestive linkage on chromosome 16 in the NIMH genetics initiative bipolar pedigrees. Am J Med Genet 2002 0.92
107 Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers. Infect Immun 2007 0.92
108 Genetic influences on craving for alcohol. Addict Behav 2012 0.91
109 Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence. Am J Med Genet B Neuropsychiatr Genet 2009 0.91
110 Stress-response pathways are altered in the hippocampus of chronic alcoholics. Alcohol 2013 0.91
111 Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers. Addict Biol 2013 0.91
112 Variants located upstream of CHRNB4 on chromosome 15q25.1 are associated with age at onset of daily smoking and habitual smoking. PLoS One 2012 0.91
113 Association analysis of genes encoding the nociceptin receptor (OPRL1) and its endogenous ligand (PNOC) with alcohol or illicit drug dependence. Addict Biol 2007 0.90
114 Copy number variation accuracy in genome-wide association studies. Hum Hered 2011 0.90
115 A comparison of diagnoses obtained from in-person and telephone interviews, using the semi-structured assessment for the genetics of alcoholism (SSAGA). J Stud Alcohol Drugs 2009 0.89
116 Gene expression in the ventral tegmental area of 5 pairs of rat lines selectively bred for high or low ethanol consumption. Pharmacol Biochem Behav 2012 0.88
117 Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study. BMC Genomics 2012 0.88
118 Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking. Genet Epidemiol 2013 0.87
119 Variations in the potassium channel genes KCNK3 and KCNK9 in relation to blood pressure and aldosterone production: an exploratory study. J Clin Endocrinol Metab 2012 0.87
120 Voluntary intravenous self-administration of alcohol detects an interaction between GABAergic manipulation and GABRG1 polymorphism genotype: a pilot study. Alcohol Clin Exp Res 2012 0.86
121 Family-based association analysis of alcohol dependence criteria and severity. Alcohol Clin Exp Res 2013 0.86
122 Changes in gene expression within the ventral tegmental area following repeated excessive binge-like alcohol drinking by alcohol-preferring (P) rats. Alcohol 2013 0.86
123 On the association of common and rare genetic variation influencing body mass index: a combined SNP and CNV analysis. BMC Genomics 2014 0.86
124 Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood. Addict Biol 2013 0.86
125 Genetic research: who is at risk for alcoholism. Alcohol Res Health 2010 0.85
126 Cis-regulatory variants affect CHRNA5 mRNA expression in populations of African and European ancestry. PLoS One 2013 0.85
127 Genomic expression analysis of rat chromosome 4 for skeletal traits at femoral neck. Physiol Genomics 2008 0.85
128 Gene expression in brain: a window on ethanol dependence, neuroadaptation, and preference. Alcohol Clin Exp Res 2003 0.85
129 Association of substance dependence phenotypes in the COGA sample. Addict Biol 2014 0.85
130 Genes influencing spinal bone mineral density in inbred F344, LEW, COP, and DA rats. Funct Integr Genomics 2009 0.84
131 Gene expression within the extended amygdala of 5 pairs of rat lines selectively bred for high or low ethanol consumption. Alcohol 2013 0.84
132 An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction. Alcohol Clin Exp Res 2014 0.84
133 Alcohol-metabolizing genes and alcohol phenotypes in an Israeli household sample. Alcohol Clin Exp Res 2013 0.84
134 A novel non-parametric regression reveals linkage on chromosome 4 for the number of externalizing symptoms in sib-pairs. Am J Med Genet B Neuropsychiatr Genet 2008 0.84
135 Differential regulation of the alcohol dehydrogenase 1B (ADH1B) and ADH1C genes by DNA methylation and histone deacetylation. Alcohol Clin Exp Res 2006 0.84
136 Association of the calcium-sensing receptor gene with blood pressure and urinary calcium in African-Americans. J Clin Endocrinol Metab 2008 0.84
137 The aggregate effect of dopamine genes on dependence symptoms among cocaine users: cross-validation of a candidate system scoring approach. Behav Genet 2012 0.83
138 Linkage for platelet monoamine oxidase (MAO) activity: results from a replication sample. Alcohol Clin Exp Res 2002 0.83
139 Evidence for association of bipolar disorder to haplotypes in the 22q12.3 region near the genes stargazin, IFT27 and parvalbumin. Am J Med Genet B Neuropsychiatr Genet 2012 0.83
140 Differentially expressed genes strongly correlated with femur strength in rats. Genomics 2009 0.83
141 Prediction of postoperative recurrence-free survival in non-small cell lung cancer by using an internationally validated gene expression model. Clin Cancer Res 2011 0.82
142 Identification of a FOXA-dependent enhancer of human alcohol dehydrogenase 4 (ADH4). Gene 2010 0.82
143 A retroviral repetitive element confers tissue-specificity to the human alcohol dehydrogenase 1C (ADH1C) gene. DNA Cell Biol 2002 0.82
144 Variation in the ADH1B proximal promoter affects expression. Chem Biol Interact 2010 0.82
145 Using RNase sequence specificity to refine the identification of RNA-protein binding regions. BMC Genomics 2008 0.82
146 Negative regulation of MHC class II gene expression by CXCR4. Exp Hematol 2006 0.81
147 Prioritizing single-nucleotide variations that potentially regulate alternative splicing. BMC Proc 2011 0.81
148 Lack of association of alcohol dependence and habitual smoking with catechol-O-methyltransferase. Alcohol Clin Exp Res 2007 0.81
149 A principal components analysis of the abbreviated Desires for Alcohol Questionnaire (DAQ). J Stud Alcohol Drugs 2010 0.81
150 Alcohol effects on central nervous system gene expression in genetic animal models. Alcohol Clin Exp Res 2005 0.81
151 Genetic association of bipolar disorder with the β(3) nicotinic receptor subunit gene. Psychiatr Genet 2011 0.81
152 Association of adenylate cyclase 10 (ADCY10) polymorphisms and bone mineral density in healthy adults. Calcif Tissue Int 2008 0.81
153 Pathway analysis of smoking quantity in multiple GWAS identifies cholinergic and sensory pathways. PLoS One 2012 0.80
154 Altering the relative abundance of GABA A receptor subunits changes GABA- and ethanol-responses in Xenopus oocytes. Alcohol Clin Exp Res 2009 0.79
155 regSNPs: a strategy for prioritizing regulatory single nucleotide substitutions. Bioinformatics 2012 0.79
156 Genetic and neurophysiological correlates of the age of onset of alcohol use disorders in adolescents and young adults. Behav Genet 2013 0.79
157 GATA-2 and HNF-3beta regulate the human alcohol dehydrogenase 1A (ADH1A) gene. DNA Cell Biol 2005 0.79
158 Characterization of a transgenic mouse line lacking photoreceptor development within the ventral retina. Exp Eye Res 2005 0.79
159 Single-nucleotide polymorphisms interact to affect ADH7 transcription. Alcohol Clin Exp Res 2014 0.79
160 Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol. Alcohol Clin Exp Res 2011 0.78
161 Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects. Biol Open 2013 0.78
162 Identification of genes influencing skeletal phenotypes in congenic P/NP rats. J Bone Miner Res 2010 0.78
163 Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1. Transl Psychiatry 2012 0.78
164 Identification of a linkage disequilibrium block in chromosome 1q associated with BMD in premenopausal white women. J Bone Miner Res 2008 0.78
165 Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample. Alcohol Clin Exp Res 2014 0.78
166 Nonreplication of an association of SGIP1 SNPs with alcohol dependence and resting theta EEG power. Psychiatr Genet 2011 0.77
167 Expression Profiling in Alcoholism Research. Alcohol Clin Exp Res 2005 0.76
168 CLCN7 polymorphisms and bone mineral density in healthy premenopausal white women and in white men. Bone 2008 0.75
169 Dosage transmission disequilibrium test (dTDT) for linkage and association detection. PLoS One 2013 0.75
170 Transcriptional changes in alveolar macrophages during Pneumocystis pneumonia. J Eukaryot Microbiol 2003 0.75
171 High-throughput quantitation of double-stranded DNA using the ABI Prism 7700 sequence detection system. Anal Biochem 2004 0.75