Published in Age Ageing on March 15, 2010
Effects of resistance training with and without caloric restriction on physical function and mobility in overweight and obese older adults: a randomized controlled trial. Am J Clin Nutr (2015) 0.93
Adiposity attenuates muscle quality and the adaptive response to resistance exercise in non-obese, healthy adults. Int J Obes (Lond) (2010) 0.86
Prevalence of overweight and obesity in the United States, 1999-2004. JAMA (2006) 72.59
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93
Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr (2004) 6.31
Serum IL-6 level and the development of disability in older persons. J Am Geriatr Soc (1999) 4.84
Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 3.96
Relationship between adipocyte size and adipokine expression and secretion. J Clin Endocrinol Metab (2006) 3.72
Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci (2000) 3.45
Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study. Diabetes (2006) 3.02
Associations of body composition with physical performance and self-reported functional limitation in elderly men and women. Am J Epidemiol (2002) 2.76
Coagulation and activation of inflammatory pathways in the development of functional decline and mortality in the elderly. Am J Med (2003) 2.41
Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc (2004) 2.29
The association of plasma IL-6 levels with functional disability in community-dwelling elderly. J Gerontol A Biol Sci Med Sci (1997) 2.27
Physical disability and muscular strength in relation to obesity and different body composition indexes in a sample of healthy elderly women. Int J Obes Relat Metab Disord (2004) 2.05
Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons. J Am Geriatr Soc (2002) 2.04
Morbidity and mortality risk associated with an overweight BMI in older men and women. Obesity (Silver Spring) (2007) 1.86
High body fatness, but not low fat-free mass, predicts disability in older men and women: the Cardiovascular Health Study. Am J Clin Nutr (1998) 1.82
Musculoskeletal disorders associated with obesity: a biomechanical perspective. Obes Rev (2006) 1.79
Effect of exercise intensity on abdominal fat loss during calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial. Am J Clin Nutr (2009) 1.77
Muscle strength as a predictor of onset of ADL dependence in people aged 75 years. Aging Clin Exp Res (2002) 1.65
The impact of obesity on the musculoskeletal system. Int J Obes (Lond) (2007) 1.57
Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation. Am J Physiol Endocrinol Metab (2004) 1.42
Protein metabolism in rheumatoid arthritis and aging. Effects of muscle strength training and tumor necrosis factor alpha. Arthritis Rheum (1996) 1.02
The relationship between body composition and physical performance in older women. J Am Geriatr Soc (1999) 0.98
Fat as an endocrine organ: influence of exercise. J Appl Physiol (1985) (2005) 0.90
Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54
Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67
Fish intake and risk of incident atrial fibrillation. Circulation (2004) 2.82
Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr (2008) 2.81
Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study). Am J Cardiol (2003) 2.49
Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action. Am J Physiol Endocrinol Metab (2006) 2.47
Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc (2004) 2.29
The effect of randomization to weight loss on total mortality in older overweight and obese adults: the ADAPT Study. J Gerontol A Biol Sci Med Sci (2010) 2.12
Chronic inflammation is associated with low physical function in older adults across multiple comorbidities. J Gerontol A Biol Sci Med Sci (2009) 2.02
Omentin plasma levels and gene expression are decreased in obesity. Diabetes (2007) 1.98
Heritability of body composition measured by DXA in the diabetes heart study. Obes Res (2005) 1.94
Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ (2005) 1.90
Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications. PLoS Med (2006) 1.81
Effect of exercise intensity on abdominal fat loss during calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial. Am J Clin Nutr (2009) 1.77
Intensive weight loss program improves physical function in older obese adults with knee osteoarthritis. Obesity (Silver Spring) (2006) 1.72
Body fat distribution and inflammation among obese older adults with and without metabolic syndrome. Obesity (Silver Spring) (2010) 1.71
Effects of birth cohort and age on body composition in a sample of community-based elderly. Am J Clin Nutr (2007) 1.65
Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance. Diabetes (2008) 1.65
Long-term physical activity and inflammatory biomarkers in older adults. Med Sci Sports Exerc (2010) 1.59
Comparative studies of resistin expression and phylogenomics in human and mouse. Biochem Biophys Res Commun (2003) 1.59
Racial differences in insulin resistance and mid-thigh fat deposition in postmenopausal women. Obes Res (2002) 1.55
Serial changes in inflammatory biomarkers after Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis (2011) 1.54
Weight loss, muscle strength, and angiotensin-converting enzyme inhibitors in older adults with congestive heart failure or hypertension. J Am Geriatr Soc (2005) 1.54
The effect of intentional weight loss on all-cause mortality in older adults: results of a randomized controlled weight-loss trial. Am J Clin Nutr (2011) 1.54
Effect of exercise training on chronic inflammation. Clin Chim Acta (2010) 1.52
Overweight and obesity over the adult life course and incident mobility limitation in older adults: the health, aging and body composition study. Am J Epidemiol (2009) 1.52
Physical function improvements after laparoscopic Roux-en-Y gastric bypass surgery. Surg Obes Relat Dis (2008) 1.50
Weighty concerns: the growing prevalence of obesity among older adults. J Am Diet Assoc (2009) 1.46
Skeletal muscle abnormalities and exercise intolerance in older patients with heart failure and preserved ejection fraction. Am J Physiol Heart Circ Physiol (2014) 1.43
Effects of hypocaloric diet and exercise training on inflammation and adipocyte lipolysis in obese postmenopausal women. J Clin Endocrinol Metab (2004) 1.40
Serum alanine aminotransferase is correlated with hematocrit in healthy human subjects. Scand J Clin Lab Invest (2012) 1.39
Plasma adiponectin and leptin levels, body composition, and glucose utilization in adult women with wide ranges of age and obesity. Diabetes Care (2003) 1.37
Metabolic syndrome and physical decline in older persons: results from the Health, Aging And Body Composition Study. J Gerontol A Biol Sci Med Sci (2009) 1.37
The metabolic syndrome in obese postmenopausal women: relationship to body composition, visceral fat, and inflammation. J Clin Endocrinol Metab (2004) 1.35
Association between inflammatory components and physical function in the health, aging, and body composition study: a principal component analysis approach. J Gerontol A Biol Sci Med Sci (2009) 1.34
Correlates of aortic stiffness in elderly individuals: a subgroup of the Cardiovascular Health Study. Am J Hypertens (2002) 1.33
Hospitalization for pneumonia in the Cardiovascular Health Study: incidence, mortality, and influence on longer-term survival. J Am Geriatr Soc (2005) 1.33
Variability of serum soluble intercellular adhesion molecule-1 measurements attributable to a common polymorphism. Clin Chem (2004) 1.33
The metabolic syndrome is associated with circulating adipokines in older adults across a wide range of adiposity. J Gerontol A Biol Sci Med Sci (2008) 1.33
Associations between body composition and gait-speed decline: results from the Health, Aging, and Body Composition study. Am J Clin Nutr (2013) 1.32
Does the amount of fat mass predict age-related loss of lean mass, muscle strength, and muscle quality in older adults? J Gerontol A Biol Sci Med Sci (2011) 1.30
The Intensive Diet and Exercise for Arthritis (IDEA) trial: design and rationale. BMC Musculoskelet Disord (2009) 1.29
Inflammatory markers and physical function among older adults with knee osteoarthritis. J Rheumatol (2004) 1.29
Abdominal adipose tissue cytokine gene expression: relationship to obesity and metabolic risk factors. Am J Physiol Endocrinol Metab (2004) 1.27
cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. Genomics (2002) 1.25
Reductions in plasma cytokine levels with weight loss improve insulin sensitivity in overweight and obese postmenopausal women. Diabetes Care (2004) 1.22
Effects of exercise on adipokines and the metabolic syndrome. Curr Diab Rep (2008) 1.21
Knee strength maintained despite loss of lean body mass during weight loss in older obese adults with knee osteoarthritis. J Gerontol A Biol Sci Med Sci (2007) 1.19
Is lost lean mass from intentional weight loss recovered during weight regain in postmenopausal women? Am J Clin Nutr (2011) 1.18
Genetic variation at NCAN locus is associated with inflammation and fibrosis in non-alcoholic fatty liver disease in morbid obesity. Hum Hered (2013) 1.17
Associations between sex steroid hormone levels and depressive symptoms in elderly men and women: results from the Health ABC study. Psychoneuroendocrinology (2007) 1.16
Cardiomyocyte-specific perilipin 5 overexpression leads to myocardial steatosis and modest cardiac dysfunction. J Lipid Res (2013) 1.12
Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study. Am J Physiol Endocrinol Metab (2010) 1.11
Chronic inflammation: role of adipose tissue and modulation by weight loss. Curr Diabetes Rev (2006) 1.11
Aerobic exercise is necessary to improve glucose utilization with moderate weight loss in women. Obesity (Silver Spring) (2006) 1.11
Fat mass loss predicts gain in physical function with intentional weight loss in older adults. J Gerontol A Biol Sci Med Sci (2012) 1.09
Differences in adipose tissue metabolism between postmenopausal and perimenopausal women. J Clin Endocrinol Metab (2002) 1.09
Hormone replacement therapy, insulin sensitivity, and abdominal obesity in postmenopausal women. Diabetes Care (2002) 1.09
Alanine aminotransferase isoenzymes: molecular cloning and quantitative analysis of tissue expression in rats and serum elevation in liver toxicity. Hepatology (2009) 1.08
Murine alanine aminotransferase: cDNA cloning, functional expression, and differential gene regulation in mouse fatty liver. Hepatology (2004) 1.06
Sex differences in insulin action and body fat distribution in overweight and obese middle-aged and older men and women. Appl Physiol Nutr Metab (2008) 1.05
Inflammatory biomarkers and physical function in older, obese adults with knee pain and self-reported osteoarthritis after intensive weight-loss therapy. J Am Geriatr Soc (2008) 1.05
Interaction between body mass index and central adiposity and risk of incident cognitive impairment and dementia: results from the Women's Health Initiative Memory Study. J Am Geriatr Soc (2011) 1.03
Angiotensin-converting enzyme insertion/deletion genotype, exercise, and physical decline. JAMA (2005) 1.01
Weight regain is related to decreases in physical activity during weight loss. Med Sci Sports Exerc (2008) 1.01
Anti-inflammatory effects of simvastatin on adipokines in type 2 diabetic patients with carotid atherosclerosis. Diab Vasc Dis Res (2009) 1.00
The role of metabolic syndrome, adiposity, and inflammation in physical performance in the Health ABC Study. J Gerontol A Biol Sci Med Sci (2012) 0.99
Feeding and insulin increase leptin translation. Importance of the leptin mRNA untranslated regions. J Biol Chem (2006) 0.98
Low testosterone levels and decline in physical performance and muscle strength in older men: findings from two prospective cohort studies. Clin Endocrinol (Oxf) (2007) 0.97
Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults. J Am Geriatr Soc (2013) 0.96
Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study. Arch Intern Med (2005) 0.96
Genetic influence on exercise-induced changes in physical function among mobility-limited older adults. Physiol Genomics (2014) 0.95
Relationship of physical function to vastus lateralis capillary density and metabolic enzyme activity in elderly men and women. Aging Clin Exp Res (2008) 0.95
Lipopolysaccharide-binding protein, a surrogate marker of microbial translocation, is associated with physical function in healthy older adults. J Gerontol A Biol Sci Med Sci (2012) 0.94
Cognition and the risk of hospitalization for serious falls in the elderly: results from the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci (2010) 0.94
Loss of function mutation in glutamic pyruvate transaminase 2 (GPT2) causes developmental encephalopathy. J Inherit Metab Dis (2015) 0.93
Heterogeneity of physical function responses to exercise training in older adults. J Am Geriatr Soc (2015) 0.93
Strength Training for Arthritis Trial (START): design and rationale. BMC Musculoskelet Disord (2013) 0.93
Plasma oxidized low-density lipoprotein levels and arterial stiffness in older adults: the health, aging, and body composition study. Hypertension (2009) 0.93
Effect of an 18-month physical activity and weight loss intervention on body composition in overweight and obese older adults. Obesity (Silver Spring) (2013) 0.91
Addition of aerobic exercise to a weight loss program increases BMD, with an associated reduction in inflammation in overweight postmenopausal women. Calcif Tissue Int (2009) 0.90
Plasminogen activator inhibitor type 1 gene polymorphisms and haplotypes are associated with plasma plasminogen activator inhibitor type 1 levels but not with myocardial infarction or stroke. Am Heart J (2006) 0.90
Racial differences in adipocyte size and relationship to the metabolic syndrome in obese women. Obes Res (2004) 0.90
Effects of lifestyle interventions on inflammatory markers in the metabolic syndrome. Front Biosci (Schol Ed) (2011) 0.89