Long-term physical activity and inflammatory biomarkers in older adults.

PubWeight™: 1.59‹?› | Rank: Top 4%

🔗 View Article (PMC 2964389)

Published in Med Sci Sports Exerc on December 01, 2010

Authors

Kristen M Beavers1, Fang-Chi Hsu, Scott Isom, Stephen B Kritchevsky, Timothy Church, Bret Goodpaster, Marco Pahor, Barbara J Nicklas

Author Affiliations

1: Section on Gerontology and Geriatric Medicine, J. Paul Sticht Center on Aging, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA. kbeavers@wfubmc.edu

Articles citing this

Effect of exercise training on chronic inflammation. Clin Chim Acta (2010) 1.52

Impact of physical activity on inflammation: effects on cardiovascular disease risk and other inflammatory conditions. Arch Med Sci (2012) 1.13

Effects of Exercise Training on Cardiorespiratory Fitness and Biomarkers of Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Am Heart Assoc (2015) 1.10

Exercise, inflammation and aging. Aging Dis (2011) 1.02

Effects of total and regional fat loss on plasma CRP and IL-6 in overweight and obese, older adults with knee osteoarthritis. Osteoarthritis Cartilage (2014) 1.01

Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults. J Am Geriatr Soc (2013) 0.96

Treating depression and depression-like behavior with physical activity: an immune perspective. Front Psychiatry (2013) 0.95

Interleukin-15, IL-15 Receptor-Alpha, and Obesity: Concordance of Laboratory Animal and Human Genetic Studies. J Obes (2011) 0.89

The effect of aerobic training on serum adiponectin and leptin levels and inflammatory markers of coronary heart disease in obese men. Biol Sport (2013) 0.87

Long-term training induces a healthy inflammatory and endocrine emergent biomarker profile in elderly men. Age (Dordr) (2011) 0.86

Total and abdominal adiposity are associated with inflammation in older adults using a factor analysis approach. J Gerontol A Biol Sci Med Sci (2012) 0.86

Inflammatory cytokine responses to progressive resistance training and supplementation with fortified milk in men aged 50+ years: an 18-month randomized controlled trial. Eur J Appl Physiol (2011) 0.82

Physical activity and inflammatory biomarkers in older adults. Med Sci Sports Exerc (2011) 0.75

Effect of interval training program on white blood cell count in the management of hypertension: A randomized controlled study. Niger Med J (2011) 0.75

Physical activity and endometriosis risk in women with infertility or pain: Systematic review and meta-analysis. Medicine (Baltimore) (2016) 0.75

Postprandial lipemic and inflammatory responses to high-fat meals: a review of the roles of acute and chronic exercise. Nutr Metab (Lond) (2016) 0.75

Aerobic Exercise for Reducing Migraine Burden: Mechanisms, Markers, and Models of Change Processes. Headache (2015) 0.75

Strength Training Decreases Inflammation and Increases Cognition and Physical Fitness in Older Women with Cognitive Impairment. Front Physiol (2017) 0.75

Articles cited by this

Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. J Gerontol A Biol Sci Med Sci (2000) 15.54

AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association Science Advisory and Coordinating Committee. Circulation (2002) 9.04

Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly. Am J Med (1999) 6.92

Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses. J Clin Invest (1998) 4.77

Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial. JAMA (2003) 4.76

Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67

The origins of age-related proinflammatory state. Blood (2004) 4.15

Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 3.96

Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci (2000) 3.45

Stabilization of the bioactivity of tumor necrosis factor by its soluble receptors. J Exp Med (1992) 3.37

Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes (2003) 3.23

The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods. Contemp Clin Trials (2005) 2.79

Association between physical activity and markers of inflammation in a healthy elderly population. Am J Epidemiol (2001) 2.68

Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure. J Am Coll Cardiol (2003) 2.35

Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study. Circulation (2001) 2.29

Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc (2004) 2.29

Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2004) 2.21

Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci (2009) 2.03

Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training. CMAJ (2005) 1.90

Combined endurance/resistance training reduces plasma TNF-alpha receptor levels in patients with chronic heart failure and coronary artery disease. Eur Heart J (2002) 1.83

Monocyte cytokine production in an elderly population: effect of age and inflammation. J Gerontol A Biol Sci Med Sci (1998) 1.79

Inflammatory markers and cardiovascular health in older adults. Cardiovasc Res (2005) 1.71

Catabolism of aging: is it an inflammatory process? Curr Opin Clin Nutr Metab Care (2003) 1.64

Exercise training as a treatment for chronic inflammation in the elderly. Exerc Sport Sci Rev (2009) 1.59

Exercise training and plasma C-reactive protein and interleukin-6 in elderly people. J Am Geriatr Soc (2008) 1.55

Association between physical activity, physical performance, and inflammatory biomarkers in an elderly population: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2005) 1.46

Plasma cytokine changes in relation to exercise intensity and muscle damage. Eur J Appl Physiol (2005) 1.33

Serum interleukin-6, soluble interleukin-6 receptor and soluble gp130 exhibit different patterns of age- and menopause-related changes. Exp Gerontol (2001) 1.31

Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians. Mech Ageing Dev (2000) 1.17

Change in circulating cytokines after 2 forms of exercise training in chronic stable heart failure. Am Heart J (2004) 1.06

Effects of resistance and multicomponent exercise on lipid profiles of older women. Maturitas (2009) 1.03

Ischemic stroke is associated with a systemic increase of blood mononuclear cells expressing interleukin-8 mRNA. Stroke (1998) 1.02

Effect of aerobic exercise training on plasma levels of tumor necrosis factor alpha in patients with heart failure. Am J Cardiol (2001) 1.01

Can adoption of regular exercise later in life prevent metabolic risk for cardiovascular disease? Diabetes Care (2005) 0.98

Effects of progressive resistance training on immune response in aging and chronic inflammation. Med Sci Sports Exerc (1996) 0.90

Effects of an exercise intervention on immunologic parameters in frail elderly nursing home residents. J Gerontol A Biol Sci Med Sci (2003) 0.90

The immune system in critical illness. Clin Chest Med (2008) 0.89

Exercise and cardiovascular outcomes in hypertensive patients in relation to structure and function of left ventricular hypertrophy: the LIFE study. Eur J Cardiovasc Prev Rehabil (2009) 0.84

1996 Remington lecture: modeling multivariate longitudinal data that are incomplete. Ann Epidemiol (1999) 0.82

Articles by these authors

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. Nature (2009) 19.56

Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34

Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy. N Engl J Med (2012) 11.48

Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet (2010) 8.89

Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis. JAMA (2003) 7.42

Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. JAMA (2006) 6.93

Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation (2005) 6.89

Effects of Testosterone Treatment in Older Men. N Engl J Med (2016) 6.66

Effects of a physical activity intervention on measures of physical performance: Results of the lifestyle interventions and independence for Elders Pilot (LIFE-P) study. J Gerontol A Biol Sci Med Sci (2006) 6.61

Prognostic value of usual gait speed in well-functioning older people--results from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2005) 6.54

Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial. Arthritis Rheum (2004) 6.46

Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons. J Gerontol A Biol Sci Med Sci (2005) 6.42

Strength, but not muscle mass, is associated with mortality in the health, aging and body composition study cohort. J Gerontol A Biol Sci Med Sci (2006) 6.08

Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation (2007) 5.87

Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation (2003) 4.67

Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study. J Am Geriatr Soc (2002) 4.55

Association between two unlinked loci at 8q24 and prostate cancer risk among European Americans. J Natl Cancer Inst (2007) 4.24

Sarcopenia: alternative definitions and associations with lower extremity function. J Am Geriatr Soc (2003) 4.02

Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci (2002) 4.00

Inflammatory markers and physical performance in older persons: the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 3.96

Walking performance and cardiovascular response: associations with age and morbidity--the Health, Aging and Body Composition Study. J Gerontol A Biol Sci Med Sci (2003) 3.95

Relation between use of angiotensin-converting enzyme inhibitors and muscle strength and physical function in older women: an observational study. Lancet (2002) 3.88

Results of repeat sigmoidoscopy 3 years after a negative examination. JAMA (2003) 3.82

Cognitive function, gait speed decline, and comorbidities: the health, aging and body composition study. J Gerontol A Biol Sci Med Sci (2007) 3.61

Sarcopenic obesity: definition, cause and consequences. Curr Opin Clin Nutr Metab Care (2008) 3.54

Anemia is associated with disability and decreased physical performance and muscle strength in the elderly. J Am Geriatr Soc (2004) 3.48

Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue. Am J Clin Nutr (2005) 3.40

Effects of intensive diet and exercise on knee joint loads, inflammation, and clinical outcomes among overweight and obese adults with knee osteoarthritis: the IDEA randomized clinical trial. JAMA (2013) 3.38

Utilization of surveillance colonoscopy in community practice. Gastroenterology (2009) 3.33

Genetic ancestry in lung-function predictions. N Engl J Med (2010) 3.30

Circulating levels of inflammatory markers and cancer risk in the health aging and body composition cohort. Cancer Epidemiol Biomarkers Prev (2005) 3.20

Hepatic steatosis and subclinical cardiovascular disease in a cohort enriched for type 2 diabetes: the Diabetes Heart Study. Am J Gastroenterol (2008) 3.16

Evidence for two independent prostate cancer risk-associated loci in the HNF1B gene at 17q12. Nat Genet (2008) 3.14

Added value of physical performance measures in predicting adverse health-related events: results from the Health, Aging And Body Composition Study. J Am Geriatr Soc (2009) 3.12

Genetic variants and associations of 25-hydroxyvitamin D concentrations with major clinical outcomes. JAMA (2012) 3.10

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. PLoS Genet (2011) 3.07

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03

Alternative definitions of sarcopenia, lower extremity performance, and functional impairment with aging in older men and women. J Am Geriatr Soc (2007) 2.94

The association of pericardial fat with calcified coronary plaque. Obesity (Silver Spring) (2008) 2.93

The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci (2014) 2.84

The effects of cognitive impairment on mortality among hospitalized patients with heart failure. Am J Med (2003) 2.83

Angiotensin-converting enzyme inhibitors and cognitive decline in older adults with hypertension: results from the Cardiovascular Health Study. Arch Intern Med (2009) 2.82

Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. Am J Clin Nutr (2008) 2.81

The lifestyle interventions and independence for elders (LIFE) pilot study: design and methods. Contemp Clin Trials (2005) 2.79

Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer. Lung Cancer (2005) 2.79

Inflammatory markers and depressed mood in older persons: results from the Health, Aging and Body Composition study. Biol Psychiatry (2003) 2.77

Strength and muscle quality in a well-functioning cohort of older adults: the Health, Aging and Body Composition Study. J Am Geriatr Soc (2003) 2.76

Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med (2013) 2.73

Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition Study. Am J Clin Nutr (2005) 2.67

Measures of physical performance and risk for progressive and catastrophic disability: results from the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci (2005) 2.59

Cystatin C and mortality risk in the elderly: the health, aging, and body composition study. J Am Soc Nephrol (2005) 2.55

The association of pericardial fat with incident coronary heart disease: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr (2009) 2.53

Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study. Am J Epidemiol (2004) 2.49

Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study). Am J Cardiol (2003) 2.49

Sarcopenia, obesity, and inflammation--results from the Trial of Angiotensin Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors study. Am J Clin Nutr (2005) 2.44

Inflammatory markers and incident heart failure risk in older adults: the Health ABC (Health, Aging, and Body Composition) study. J Am Coll Cardiol (2010) 2.43

Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial. Am J Clin Nutr (2004) 2.37

Potential impact of adding genetic markers to clinical parameters in predicting prostate biopsy outcomes in men following an initial negative biopsy: findings from the REDUCE trial. Eur Urol (2012) 2.34

Incident heart failure prediction in the elderly: the health ABC heart failure score. Circ Heart Fail (2008) 2.33

Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc (2004) 2.29

Hemoglobin levels and skeletal muscle: results from the InCHIANTI study. J Gerontol A Biol Sci Med Sci (2004) 2.28

Sequence variants at 22q13 are associated with prostate cancer risk. Cancer Res (2009) 2.27

Flexible sigmoidoscopy in the PLCO cancer screening trial: results from the baseline screening examination of a randomized trial. J Natl Cancer Inst (2005) 2.27

The Lifestyle Interventions and Independence for Elders Study: design and methods. J Gerontol A Biol Sci Med Sci (2011) 2.26

Exercise and depressive symptoms: a comparison of aerobic and resistance exercise effects on emotional and physical function in older persons with high and low depressive symptomatology. J Gerontol B Psychol Sci Soc Sci (2002) 2.22

The relationship of antiresorptive drug use to structural findings and symptoms of knee osteoarthritis. Arthritis Rheum (2004) 2.22

Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study. J Am Geriatr Soc (2004) 2.21

Association of inflammatory markers with socioeconomic status. J Gerontol A Biol Sci Med Sci (2006) 2.20

Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care (2010) 2.14

Change in physical performance over time in older women: the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci (2002) 2.13

The effect of randomization to weight loss on total mortality in older overweight and obese adults: the ADAPT Study. J Gerontol A Biol Sci Med Sci (2010) 2.12

Physical function and self-rated health status as predictors of mortality: results from longitudinal analysis in the ilSIRENTE study. BMC Geriatr (2008) 2.08

NIH working group report: Innovative research to improve maintenance of weight loss. Obesity (Silver Spring) (2014) 2.08

Effects of physical activity on strength and skeletal muscle fat infiltration in older adults: a randomized controlled trial. J Appl Physiol (1985) (2008) 2.06

Do muscle mass, muscle density, strength, and physical function similarly influence risk of hospitalization in older adults? J Am Geriatr Soc (2009) 2.04

Muscle mass predicts outcomes following liver transplantation. Liver Transpl (2013) 2.04

Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci (2009) 2.03