Paul M Kaye

Author PubWeight™ 58.21‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med 2002 1.86
2 Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses. Nat Med 2003 1.75
3 Posttranscriptional regulation of II10 gene expression allows natural killer cells to express immunoregulatory function. Immunity 2008 1.65
4 Stromal cells direct local differentiation of regulatory dendritic cells. Immunity 2004 1.58
5 CD11b regulates recruitment of alveolar macrophages but not pulmonary dendritic cells after pneumococcal challenge. J Infect Dis 2005 1.52
6 Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis. Nat Immunol 2002 1.44
7 Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells. Eur J Immunol 2006 1.44
8 Alveolar macrophages transport pathogens to lung draining lymph nodes. J Immunol 2009 1.33
9 Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis. Trends Parasitol 2004 1.32
10 Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. PLoS Pathog 2010 1.32
11 A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection. Am J Pathol 2002 1.32
12 Dendritic cells at the host-pathogen interface. Nat Immunol 2002 1.30
13 Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity. Infect Immun 2003 1.28
14 Immunotherapy with OX40L-Fc or anti-CTLA-4 enhances local tissue responses and killing of Leishmania donovani. Eur J Immunol 2004 1.19
15 Loss of dendritic cell migration and impaired resistance to Leishmania donovani infection in mice deficient in CCL19 and CCL21. J Immunol 2006 1.19
16 Distinct roles for lymphotoxin-alpha and tumor necrosis factor in the control of Leishmania donovani infection. Am J Pathol 2004 1.17
17 Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. PLoS Negl Trop Dis 2009 1.14
18 Localization of marginal zone macrophages is regulated by C-C chemokine ligands 21/19. J Immunol 2004 1.09
19 The role played by tumor necrosis factor during localized and systemic infection with Streptococcus pneumoniae. J Infect Dis 2005 1.09
20 Stromal-cell regulation of dendritic-cell differentiation and function. Trends Immunol 2006 1.01
21 IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis. PLoS Pathog 2012 1.00
22 CD8+ T-cell priming regulated by cytokines of the innate immune system. Trends Mol Med 2004 0.99
23 Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. Infect Immun 2006 0.98
24 Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7. PLoS Pathog 2010 0.98
25 Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis. J Infect Dis 2012 0.98
26 Expression of vFLIP in a lentiviral vaccine vector activates NF-{kappa}B, matures dendritic cells, and increases CD8+ T-cell responses. J Virol 2008 0.97
27 The Schistosoma mansoni hepatic egg granuloma provides a favorable microenvironment for sustained growth of Leishmania donovani. Am J Pathol 2006 0.95
28 Functional complexity of the Leishmania granuloma and the potential of in silico modeling. Front Immunol 2013 0.95
29 Temporal regulation of interleukin-12p70 (IL-12p70) and IL-12-related cytokines in splenic dendritic cell subsets during Leishmania donovani infection. Infect Immun 2007 0.94
30 VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis. PLoS Pathog 2008 0.94
31 Compartment-specific remodeling of splenic micro-architecture during experimental visceral leishmaniasis. Am J Pathol 2011 0.92
32 Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice. J Clin Invest 2010 0.92
33 Invariant NKT cells are essential for the regulation of hepatic CXCL10 gene expression during Leishmania donovani infection. Infect Immun 2005 0.91
34 Functional analysis of Leishmania cyclopropane fatty acid synthetase. PLoS One 2012 0.91
35 Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major. J Immunol 2006 0.89
36 Endogenous IL-13 plays a crucial role in liver granuloma maturation during Leishmania donovani infection, independent of IL-4Rα-responsive macrophages and neutrophils. J Infect Dis 2011 0.89
37 Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. J Immunol 2009 0.89
38 Chronic Leishmania donovani infection promotes bystander CD8+-T-cell expansion and heterologous immunity. Infect Immun 2005 0.87
39 Evidence for the involvement of lung-specific gammadelta T cell subsets in local responses to Streptococcus pneumoniae infection. Eur J Immunol 2007 0.87
40 Stromal cell-derived CXCL12 and CCL8 cooperate to support increased development of regulatory dendritic cells following Leishmania infection. J Immunol 2010 0.86
41 A transcriptomic network identified in uninfected macrophages responding to inflammation controls intracellular pathogen survival. Cell Host Microbe 2013 0.86
42 Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activation. Eur J Immunol 2010 0.86
43 SIGNR1-negative red pulp macrophages protect against acute streptococcal sepsis after Leishmania donovani-induced loss of marginal zone macrophages. Am J Pathol 2009 0.85
44 Immunomodulators: use in combined therapy against leishmaniasis. Expert Rev Anti Infect Ther 2010 0.85
45 In vivo recognition of ovalbumin expressed by transgenic Leishmania is determined by its subcellular localization. J Immunol 2006 0.85
46 B cell: T cell interactions occur within hepatic granulomas during experimental visceral leishmaniasis. PLoS One 2012 0.85
47 The fate of heterologous CD4+ T cells during Leishmania donovani infection. Eur J Immunol 2005 0.84
48 Interferon regulatory factor 7 contributes to the control of Leishmania donovani in the mouse liver. Infect Immun 2010 0.82
49 Leishmania-induced inhibition of macrophage antigen presentation analyzed at the single-cell level. J Immunol 2003 0.81
50 Critical roles for LIGHT and its receptors in generating T cell-mediated immunity during Leishmania donovani infection. PLoS Pathog 2011 0.81
51 Tissue requirements for establishing long-term CD4+ T cell-mediated immunity following Leishmania donovani infection. J Immunol 2014 0.81
52 Leishmania-host interactions: what has imaging taught us? Cell Microbiol 2011 0.81
53 Stromal cell induction of regulatory dendritic cells. Front Immunol 2012 0.79
54 IRF7 regulates TLR2-mediated activation of splenic CD11c(hi) dendritic cells. PLoS One 2012 0.78
55 Regiospecific methylation of a dietary flavonoid scaffold selectively enhances IL-1β production following Toll-like receptor 2 stimulation in THP-1 monocytes. J Biol Chem 2013 0.77
56 Oral activated charcoal prevents experimental cerebral malaria in mice and in a randomized controlled clinical trial in man did not interfere with the pharmacokinetics of parenteral artesunate. PLoS One 2010 0.76