Published in J Clin Invest on March 15, 2010
The secret ally: immunostimulation by anticancer drugs. Nat Rev Drug Discov (2012) 3.60
Leishmaniasis: complexity at the host-pathogen interface. Nat Rev Microbiol (2011) 2.93
Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology. PLoS Pathog (2016) 1.44
Toll-like receptors in leishmania infections: guardians or promoters? J Parasitol Res (2012) 1.03
IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis. PLoS Pathog (2012) 1.00
Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis. J Infect Dis (2012) 0.98
Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis. Semin Immunopathol (2012) 0.98
Regulation of immunity during visceral Leishmania infection. Parasit Vectors (2016) 0.92
Compartment-specific remodeling of splenic micro-architecture during experimental visceral leishmaniasis. Am J Pathol (2011) 0.92
Immune regulation during chronic visceral leishmaniasis. PLoS Negl Trop Dis (2014) 0.88
Growth factor and Th2 cytokine signaling pathways converge at STAT6 to promote arginase expression in progressive experimental visceral leishmaniasis. PLoS Pathog (2014) 0.87
Lessons from other diseases: granulomatous inflammation in leishmaniasis. Semin Immunopathol (2015) 0.85
Differential Regulation of the Immune Response in the Spleen and Liver of Mice Infected with Leishmania donovani. J Trop Med (2011) 0.84
Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis. Immunology (2013) 0.81
The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis. Front Immunol (2016) 0.79
The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection. PLoS Pathog (2015) 0.78
FasL and TRAIL signaling in the skin during cutaneous leishmaniasis - implications for tissue immunopathology and infectious control. Front Immunol (2012) 0.77
Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages. Sci Rep (2016) 0.76
Angiogenesis in health and disease. Nat Med (2003) 14.02
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell (2007) 12.52
IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol (1991) 11.04
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship. Clin Cancer Res (2003) 9.92
An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol (2003) 8.23
Visceral leishmaniasis: what are the needs for diagnosis, treatment and control? Nat Rev Microbiol (2007) 7.36
Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes. Immunity (2006) 7.22
Structure and function of the spleen. Nat Rev Immunol (2005) 6.38
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med (2002) 5.50
Trophic macrophages in development and disease. Nat Rev Immunol (2009) 5.37
Leishmaniasis and poverty. Trends Parasitol (2006) 4.25
Interferon-gamma, the activated macrophage, and host defense against microbial challenge. Ann Intern Med (1988) 3.43
The role of IL-10 in promoting disease progression in leishmaniasis. J Immunol (2001) 3.21
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone. Nat Immunol (2008) 2.93
Phase 4 trial of miltefosine for the treatment of Indian visceral leishmaniasis. J Infect Dis (2007) 2.74
Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens. Immunity (2009) 2.68
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature (2007) 2.65
Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection. Proc Natl Acad Sci U S A (2007) 2.39
Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence. Nat Rev Immunol (2008) 2.30
M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J Exp Med (2009) 2.29
Ectopic lymphoid tissues and local immunity. Semin Immunol (2008) 2.18
Sorafenib, but not sunitinib, affects function of dendritic cells and induction of primary immune responses. Blood (2008) 2.09
Pancreatitis induced by pentavalent antimonial agents during treatment of leishmaniasis. Clin Infect Dis (1994) 2.02
Leishmaniasis in Sudan. Visceral leishmaniasis. Trans R Soc Trop Med Hyg (2001) 2.00
Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats. Hepatology (2007) 1.88
Fibroblastic reticular cells guide T lymphocyte entry into and migration within the splenic T cell zone. J Immunol (2008) 1.75
Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination. J Leukoc Biol (1989) 1.71
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies. Cancer Res (2008) 1.69
Morphology of the spleen and lymph nodes in fatal visceral leishmaniasis. Immunology (1977) 1.68
Efficacy of liposomal amphotericin B for secondary prophylaxis of visceral leishmaniasis in HIV-infected patients. J Antimicrob Chemother (2007) 1.66
Neutralization of IL-12 demonstrates the existence of discrete organ-specific phases in the control of Leishmania donovani. Eur J Immunol (1998) 1.65
The immunopathology of experimental visceral leishmaniasis. Immunol Rev (2004) 1.64
Chemotherapy in the treatment and control of leishmaniasis. Adv Parasitol (2006) 1.56
Balancing immunity and pathology in visceral leishmaniasis. Immunol Cell Biol (2006) 1.55
IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani. J Clin Invest (2009) 1.53
New treatment approach in Indian visceral leishmaniasis: single-dose liposomal amphotericin B followed by short-course oral miltefosine. Clin Infect Dis (2008) 1.51
Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis. Infect Immun (2000) 1.44
Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis. Nat Immunol (2002) 1.44
Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells. Eur J Immunol (2006) 1.44
Specific remodeling of splenic architecture by cytomegalovirus. PLoS Pathog (2006) 1.43
Hepatotoxicity of sodium stibogluconate in leishmaniasis. Lancet (1993) 1.42
Amphotericin B treatment for Indian visceral leishmaniasis: response to 15 daily versus alternate-day infusions. Clin Infect Dis (2007) 1.39
Organ-specific immune responses associated with infectious disease. Immunol Today (2000) 1.39
Blockade of CTLA-4 enhances host resistance to the intracellular pathogen, Leishmania donovani. J Immunol (1998) 1.38
Chronic inflammation: links with angiogenesis and wound healing. Am J Pathol (1998) 1.37
Sunitinib-induced myeloid lineage redistribution in renal cell cancer patients: CD1c+ dendritic cell frequency predicts progression-free survival. Clin Cancer Res (2008) 1.36
Destruction of follicular dendritic cells during chronic visceral leishmaniasis. J Immunol (1997) 1.36
Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis. Eur J Immunol (2000) 1.32
A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection. Am J Pathol (2002) 1.32
Acquired resistance and granuloma formation in experimental visceral leishmaniasis. Differential T cell and lymphokine roles in initial versus established immunity. J Immunol (1992) 1.31
Contribution of neural crest-derived cells in the embryonic and adult thymus. J Immunol (2008) 1.30
Phase 2 trial of WR6026, an orally administered 8-aminoquinoline, in the treatment of visceral leishmaniasis caused by Leishmania chagasi. Am J Trop Med Hyg (2001) 1.27
Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis. Am J Pathol (2009) 1.27
Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses. PLoS Pathog (2008) 1.27
Macrophage-derived angiogenesis factors. Pharmacol Ther (1991) 1.26
Manipulating angiogenesis in medicine. J Intern Med (2004) 1.22
Immunotherapy with OX40L-Fc or anti-CTLA-4 enhances local tissue responses and killing of Leishmania donovani. Eur J Immunol (2004) 1.19
HIV-1 immune suppression and antimalarial treatment outcome in Zambian adults with uncomplicated malaria. J Infect Dis (2006) 1.17
Assessment of vascular remodeling under antiangiogenic therapy using DCE-MRI and vessel size imaging. J Magn Reson Imaging (2009) 1.15
Immunotherapy for drug-refractory mucosal leishmaniasis. J Infect Dis (2006) 1.12
Magnitude of unresponsiveness to sodium stibogluconate in the treatment of visceral leishmaniasis in Bihar. Natl Med J India (2005) 1.11
Shaping the immune response to parasites: role of dendritic cells. Curr Opin Immunol (2003) 1.06
Cure of antimony-unresponsive Indian visceral leishmaniasis with amphotericin B lipid complex. J Infect Dis (1996) 1.03
Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses. Semin Immunol (2008) 1.03
Angiogenesis in rheumatoid arthritis. Front Biosci (2005) 1.03
Modulation of T-cell costimulation as immunotherapy or immunochemotherapy in experimental visceral leishmaniasis. Infect Immun (2003) 1.02
The role of angiogenesis in rheumatoid arthritis: recent developments. Ann Rheum Dis (2000) 1.02
Short-course paromomycin treatment of visceral leishmaniasis in India: 14-day vs 21-day treatment. Clin Infect Dis (2009) 0.99
Alterations of splenic architecture in malaria are induced independently of Toll-like receptors 2, 4, and 9 or MyD88 and may affect antibody affinity. Infect Immun (2008) 0.98
Successful treatment of refractory visceral leishmaniasis in India using antimony plus interferon-gamma. J Infect Dis (1994) 0.96
Visceral leishmaniasis in the German shepherd dog. II. Pathology. Vet Pathol (1984) 0.95
The extracellular matrix of the spleen as a potential organizer of immune cell compartments. Semin Immunol (2008) 0.95
Long term failure of miltefosine in the treatment of refractory visceral leishmaniasis in AIDS patients. Scand J Infect Dis (2007) 0.94
CD8+ T lymphocyte-mediated loss of marginal metallophilic macrophages following infection with Plasmodium chabaudi chabaudi AS. J Immunol (2006) 0.92
Angiogenesis in inflammation. Autoimmun Rev (2004) 0.86
Consultation meeting on the development of therapeutic vaccines for post kala azar dermal leishmaniasis. Kinetoplastid Biol Dis (2007) 0.83
Leishmaniosis--a report about the microvascular and cellular architecture of the infected spleen in Canis familiaris. Microsc Res Tech (2006) 0.81
Immunochemotherapy for visceral leishmaniasis: a controlled pilot trial of antimony versus antimony plus interferon-gamma. Am J Trop Med Hyg (1993) 0.81
Interleukin 10 receptor blockade--pentavalent antimony treatment in experimental visceral leishmaniasis. Acta Trop (2005) 0.78
Clinical and fundamental aspects of angiogenesis and anti-angiogenesis. Acta Clin Belg (2007) 0.77
Introduction: FDC in health and disease. Semin Immunol (2002) 0.76
Transgenic mice with hematopoietic and lymphoid specific expression of Cre. Eur J Immunol (2003) 5.73
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol (2009) 3.27
The importance of the spleen in malaria. Trends Parasitol (2005) 2.23
Mental health and quality of life of gay men and lesbians in England and Wales: controlled, cross-sectional study. Br J Psychiatry (2003) 2.20
Toll-like receptor 4 expression is required to control chronic Mycobacterium tuberculosis infection in mice. J Immunol (2002) 2.17
Attention network hypoconnectivity with default and affective network hyperconnectivity in adults diagnosed with attention-deficit/hyperactivity disorder in childhood. JAMA Psychiatry (2013) 2.11
Locally up-regulated lymphotoxin alpha, not systemic tumor necrosis factor alpha, is the principle mediator of murine cerebral malaria. J Exp Med (2002) 1.86
Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses. Nat Med (2003) 1.75
Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Antimicrob Agents Chemother (2006) 1.72
Posttranscriptional regulation of II10 gene expression allows natural killer cells to express immunoregulatory function. Immunity (2008) 1.65
The immunopathology of experimental visceral leishmaniasis. Immunol Rev (2004) 1.64
Stromal cells direct local differentiation of regulatory dendritic cells. Immunity (2004) 1.58
CD11b regulates recruitment of alveolar macrophages but not pulmonary dendritic cells after pneumococcal challenge. J Infect Dis (2005) 1.52
Serodiagnosis of dengue during an outbreak at a tertiary care hospital in Delhi. Indian J Med Res (2005) 1.51
Determining disease intervention strategies using spatially resolved simulations. PLoS One (2013) 1.49
Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis. Nat Immunol (2002) 1.44
Distinct roles for IL-6 and IL-12p40 in mediating protection against Leishmania donovani and the expansion of IL-10+ CD4+ T cells. Eur J Immunol (2006) 1.44
Cocirculation of dengue serotypes, Delhi, India, 2003. Emerg Infect Dis (2006) 1.41
Adherence with topical treatment is poor compared with adherence with oral agents: implications for effective clinical use of topical agents. J Am Acad Dermatol (2006) 1.40
Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences. Immunity (2002) 1.40
Environmental dimensionality controls the interaction of phagocytes with the pathogenic fungi Aspergillus fumigatus and Candida albicans. PLoS Pathog (2007) 1.39
Rates and predictors of mental illness in gay men, lesbians and bisexual men and women: Results from a survey based in England and Wales. Br J Psychiatry (2004) 1.36
Alveolar macrophages transport pathogens to lung draining lymph nodes. J Immunol (2009) 1.33
Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis. Trends Parasitol (2004) 1.32
Dynamic imaging of experimental Leishmania donovani-induced hepatic granulomas detects Kupffer cell-restricted antigen presentation to antigen-specific CD8 T cells. PLoS Pathog (2010) 1.32
A role for tumor necrosis factor-alpha in remodeling the splenic marginal zone during Leishmania donovani infection. Am J Pathol (2002) 1.32
Dendritic cells at the host-pathogen interface. Nat Immunol (2002) 1.30
Contribution of neural crest-derived cells in the embryonic and adult thymus. J Immunol (2008) 1.30
N-myristoyltransferase from Leishmania donovani: structural and functional characterisation of a potential drug target for visceral leishmaniasis. J Mol Biol (2009) 1.28
Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity. Infect Immun (2003) 1.28
IL-7-producing stromal cells are critical for lymph node remodeling. Blood (2012) 1.22
The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release. Immunity (2013) 1.21
Immunotherapy with OX40L-Fc or anti-CTLA-4 enhances local tissue responses and killing of Leishmania donovani. Eur J Immunol (2004) 1.19
Loss of dendritic cell migration and impaired resistance to Leishmania donovani infection in mice deficient in CCL19 and CCL21. J Immunol (2006) 1.19
Distinct roles for lymphotoxin-alpha and tumor necrosis factor in the control of Leishmania donovani infection. Am J Pathol (2004) 1.17
Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. PLoS Negl Trop Dis (2009) 1.14
IL7-hCD25 and IL7-Cre BAC transgenic mouse lines: new tools for analysis of IL-7 expressing cells. Genesis (2009) 1.12
Plasmodium strain determines dendritic cell function essential for survival from malaria. PLoS Pathog (2007) 1.12
Localization of marginal zone macrophages is regulated by C-C chemokine ligands 21/19. J Immunol (2004) 1.09
The role played by tumor necrosis factor during localized and systemic infection with Streptococcus pneumoniae. J Infect Dis (2005) 1.09
Spartan: a comprehensive tool for understanding uncertainty in simulations of biological systems. PLoS Comput Biol (2013) 1.09
Stromal-cell regulation of dendritic-cell differentiation and function. Trends Immunol (2006) 1.01
The hidden infertile: infertile women without pregnancy intent in the United States. Fertil Steril (2009) 1.01
Galectin-1-expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow. Blood (2011) 1.00
IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis. PLoS Pathog (2012) 1.00
CD8+ T-cell priming regulated by cytokines of the innate immune system. Trends Mol Med (2004) 0.99
Therapeutic vaccination with recombinant adenovirus reduces splenic parasite burden in experimental visceral leishmaniasis. J Infect Dis (2012) 0.98
Natural killer receptors: the burden of a name. J Exp Med (2010) 0.98
Vision-related quality of life in patients with complete homonymous hemianopia post stroke. Top Stroke Rehabil (2010) 0.98
Adoptive immunotherapy against experimental visceral leishmaniasis with CD8+ T cells requires the presence of cognate antigen. Infect Immun (2006) 0.98
Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7. PLoS Pathog (2010) 0.98
Expression of vFLIP in a lentiviral vaccine vector activates NF-{kappa}B, matures dendritic cells, and increases CD8+ T-cell responses. J Virol (2008) 0.97
The Schistosoma mansoni hepatic egg granuloma provides a favorable microenvironment for sustained growth of Leishmania donovani. Am J Pathol (2006) 0.95
Functional complexity of the Leishmania granuloma and the potential of in silico modeling. Front Immunol (2013) 0.95
IL-7: the global builder of the innate lymphoid network and beyond, one niche at a time. Semin Immunol (2012) 0.94
Temporal regulation of interleukin-12p70 (IL-12p70) and IL-12-related cytokines in splenic dendritic cell subsets during Leishmania donovani infection. Infect Immun (2007) 0.94
VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis. PLoS Pathog (2008) 0.94
Compartment-specific remodeling of splenic micro-architecture during experimental visceral leishmaniasis. Am J Pathol (2011) 0.92
Invariant NKT cells are essential for the regulation of hepatic CXCL10 gene expression during Leishmania donovani infection. Infect Immun (2005) 0.91
Dendritic cell functional properties in a three-dimensional tissue model of human lung mucosa. Am J Physiol Lung Cell Mol Physiol (2011) 0.91
Functional analysis of Leishmania cyclopropane fatty acid synthetase. PLoS One (2012) 0.91
Enhanced immune response in Mycobacterium bovis bacille calmette guerin (BCG)-infected IL-10-deficient mice. Clin Chem Lab Med (2002) 0.90
Antigen-experienced T cells limit the priming of naive T cells during infection with Leishmania major. J Immunol (2006) 0.89
Endogenous IL-13 plays a crucial role in liver granuloma maturation during Leishmania donovani infection, independent of IL-4Rα-responsive macrophages and neutrophils. J Infect Dis (2011) 0.89
Dendritic cells matured by inflammation induce CD86-dependent priming of naive CD8+ T cells in the absence of their cognate peptide antigen. J Immunol (2009) 0.89
Chronic Leishmania donovani infection promotes bystander CD8+-T-cell expansion and heterologous immunity. Infect Immun (2005) 0.87
Evidence for the involvement of lung-specific gammadelta T cell subsets in local responses to Streptococcus pneumoniae infection. Eur J Immunol (2007) 0.87
Blood flukes exploit Peyer's Patch lymphoid tissue to facilitate transmission from the mammalian host. PLoS Pathog (2012) 0.87
A transcriptomic network identified in uninfected macrophages responding to inflammation controls intracellular pathogen survival. Cell Host Microbe (2013) 0.86
Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activation. Eur J Immunol (2010) 0.86